ZA927500B - Substituted imidazolyl-propenoic acid derivatives. - Google Patents

Substituted imidazolyl-propenoic acid derivatives.

Info

Publication number: ZA927500B
Authority: ZA; South Africa
Prior art keywords: acid derivatives; propenoic acid; substituted imidazolyl; imidazolyl; substituted
Prior art date: 1991-10-01

Application number

ZA927500A

Inventor

Thomas Kraemer

Juergen Dressel

Rudolf Hanko

Walter Huebsch

Ulrich Mueller

Matthias Mueller-Gliemann

Martin Beuck

Stanislav Kazda

Johannes-Peter Stasch

Andreas Knorr

Stefan Wohlfeil

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-01

Filing date

1992-09-30

Publication date

1993-05-03

1992-09-30 Application filed by Bayer Ag filed Critical Bayer Ag

1993-05-03 Publication of ZA927500B publication Critical patent/ZA927500B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA927500A 1991-10-01 1992-09-30 Substituted imidazolyl-propenoic acid derivatives. ZA927500B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4132632A DE4132632A1 (en)	1991-10-01	1991-10-01	SUBSTITUTED IMIDAZOLYL-PROPENSAEUREDERIVATE

Publications (1)

Publication Number	Publication Date
ZA927500B true ZA927500B (en)	1993-05-03

Family

ID=6441874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA927500A ZA927500B (en)	1991-10-01	1992-09-30	Substituted imidazolyl-propenoic acid derivatives.

Country Status (15)

Country	Link
EP (1)	EP0539713A1 (en)
JP (1)	JPH05213939A (en)
KR (1)	KR930007937A (en)
AU (1)	AU646596B2 (en)
CA (1)	CA2079268A1 (en)
CZ (1)	CZ297692A3 (en)
DE (1)	DE4132632A1 (en)
FI (1)	FI924355A (en)
HU (1)	HUT62576A (en)
IL (1)	IL103293A0 (en)
MX (1)	MX9205435A (en)
NO (1)	NO923580L (en)
SK (1)	SK297692A3 (en)
TW (1)	TW206223B (en)
ZA (1)	ZA927500B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4132633A1 (en) *	1991-10-01	1993-04-08	Bayer Ag	CYCLICALLY SUBSTITUTED IMIDAZOLYL-PROPENEASE DERIVATIVES
DE4132631A1 (en) *	1991-10-01	1993-04-08	Bayer Ag	IMIDAZOLYL-propenoic acid derivatives
AT398202B (en) *	1991-10-04	1994-10-25	Chem Pharm Forsch Gmbh	NEW IMIDAZOLE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
GB9218449D0 (en)	1992-08-29	1992-10-14	Boots Co Plc	Therapeutic agents
PT668272E (en) *	1994-01-28	2000-10-31	Takeda Chemical Industries Ltd	PROCESS FOR THE PRODUCTION OF TETRAZOLYL COMPOUNDS
EP0754042A4 (en) *	1994-03-29	2004-06-23	Merck & Co Inc	Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
TR200805275T2 (en) *	1998-12-23	2008-09-22	Novartis Ag	Use of the AT-1 receptor antagonist or AT-2 receptor modulator for the treatment of diseases caused by increased AT-1 or AT-2 receptors.
EP1013273A1 (en) *	1998-12-23	2000-06-28	Novartis AG	Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors
US6465502B1 (en) *	1998-12-23	2002-10-15	Novartis Ag	Additional therapeutic use
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP5546451B2 (en)	2007-06-04	2014-07-09	シナジーファーマシューティカルズインコーポレイテッド	Agonyl cyclase agonists useful in the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2810951B1 (en)	2008-06-04	2017-03-15	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
JP2016514671A (en)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	Guanylate cyclase agonists and uses thereof
EP2968439A2 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
EP4424697A2 (en)	2013-06-05	2024-09-04	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG52330A1 (en) *	1989-06-14	1998-09-28	Smithkline Beecham Corp	Imidazolyl-alkenoic acids
EP0403158A3 (en) *	1989-06-14	1991-12-18	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids
GB9017482D0 (en) *	1990-08-09	1990-09-26	Ici Plc	Manufacturing process

1991
- 1991-10-01 DE DE4132632A patent/DE4132632A1/en not_active Withdrawn
1992
- 1992-09-14 TW TW081107194A patent/TW206223B/zh active
- 1992-09-15 NO NO92923580A patent/NO923580L/en unknown
- 1992-09-18 EP EP92115969A patent/EP0539713A1/en not_active Withdrawn
- 1992-09-24 MX MX9205435A patent/MX9205435A/en unknown
- 1992-09-25 IL IL103293A patent/IL103293A0/en unknown
- 1992-09-25 JP JP4279241A patent/JPH05213939A/en active Pending
- 1992-09-28 CA CA002079268A patent/CA2079268A1/en not_active Abandoned
- 1992-09-29 CZ CS922976A patent/CZ297692A3/en unknown
- 1992-09-29 FI FI924355A patent/FI924355A/en not_active Application Discontinuation
- 1992-09-29 SK SK2976-92A patent/SK297692A3/en unknown
- 1992-09-29 AU AU26024/92A patent/AU646596B2/en not_active Expired - Fee Related
- 1992-09-30 KR KR1019920017892A patent/KR930007937A/en not_active Application Discontinuation
- 1992-09-30 ZA ZA927500A patent/ZA927500B/en unknown
- 1992-10-01 HU HU9203123A patent/HUT62576A/en unknown

Also Published As

Publication number	Publication date
CZ297692A3 (en)	1993-04-14
IL103293A0 (en)	1993-02-21
TW206223B (en)	1993-05-21
DE4132632A1 (en)	1993-04-08
FI924355A (en)	1993-04-02
JPH05213939A (en)	1993-08-24
KR930007937A (en)	1993-05-20
CA2079268A1 (en)	1993-04-02
AU646596B2 (en)	1994-02-24
HUT62576A (en)	1993-05-28
AU2602492A (en)	1993-04-08
MX9205435A (en)	1993-04-01
NO923580L (en)	1993-04-02
NO923580D0 (en)	1992-09-15
FI924355A0 (en)	1992-09-29
HU9203123D0 (en)	1992-12-28
EP0539713A1 (en)	1993-05-05
SK297692A3 (en)	1995-09-13

Publication	Publication Date	Title
ZA924743B (en)	1993-03-31	7-azaisoindolinyl-quinolone-and-naphthyrindonecarboxylic acid derivatives
EP0641203A4 (en)	1994-06-09	Imidazolyl-alkenoic acids.
ZA92908B (en)	1993-08-09	Compounds.
ZA934603B (en)	1994-01-05	thiazolylvinylphenyl derivatives.
GR3017462T3 (en)	1995-12-31	2-Hydroxy-2-phenylethylamine derivatives as beta-3-adrenoceptor agonists.
PH30227A (en)	1997-02-05	7-Isoindolinyl-quinolone-carboxylic acid derivatives
IL103538A0 (en)	1993-03-15	Quinoxaline-carboxylic and-phosphonic acid derivatives
ZA927955B (en)	1993-08-13	Cyclohexaneacetic acid derivatives.
ZA927500B (en)	1993-05-03	Substituted imidazolyl-propenoic acid derivatives.
ZA927499B (en)	1993-05-03	Cyclic-substituted imidazolyl-propenoic acid derivatives.
ZA927501B (en)	1993-05-03	Imidazolyl-propenoic acid derivatives.
ZA929330B (en)	1993-06-04	Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivatives.
OA09716A (en)	1993-08-30	Benzoxaiole derivatives.
EP0593464A4 (en)	1993-02-12	Benzoic acid derivatives.
ZA925081B (en)	1993-04-28	Substituted carboxymethoxysuccinic acid.
HU9400745D0 (en)	1994-06-28	2,4-diamino-3-hydroxy-carboxylic acid derivatives
HU9302728D0 (en)	1993-12-28	Pyridazinone-acetic acid derivatives
ZA928275B (en)	1993-05-04	Quinoxaline-carboxylic and -phosphonic acid derivatives.
ATE121078T1 (en)	1995-04-15	PROPENEIC ACID DERIVATIVES.
HU9202296D0 (en)	1992-10-28	3,4-dehydro-piperidine derivatives
ZA922831B (en)	1993-01-27	Novel thienyl-nonatetraenoic acid derivatives
ZA93737B (en)	1993-09-06	Aminobenzoic acid derivatives.
ZA924932B (en)	1994-01-03	4-amino-3-hydroxycarboxylic acid derivatives
ZA924515B (en)	1993-03-31	7-isoindolinyl-quinolone-and naphthyridonecarboxylic acid derivatives
ZA922022B (en)	1992-11-25	N-acyl-alpha-amino acid derivatives