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ZA915727B - Quinuclidine derivatives - Google Patents

Quinuclidine derivatives

Info

Publication number
ZA915727B
ZA915727B ZA915727A ZA915727A ZA915727B ZA 915727 B ZA915727 B ZA 915727B ZA 915727 A ZA915727 A ZA 915727A ZA 915727 A ZA915727 A ZA 915727A ZA 915727 B ZA915727 B ZA 915727B
Authority
ZA
South Africa
Prior art keywords
quinuclidine derivatives
quinuclidine
derivatives
migraine
antagonists
Prior art date
Application number
ZA915727A
Other languages
English (en)
Inventor
John A Lowe Iii
A Lowe John Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA915727B publication Critical patent/ZA915727B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Soft Magnetic Materials (AREA)
  • Paper (AREA)
  • Control Of Electric Motors In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA915727A 1990-07-23 1991-07-22 Quinuclidine derivatives ZA915727B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55744290A 1990-07-23 1990-07-23

Publications (1)

Publication Number Publication Date
ZA915727B true ZA915727B (en) 1993-02-24

Family

ID=24225412

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA915727A ZA915727B (en) 1990-07-23 1991-07-22 Quinuclidine derivatives

Country Status (25)

Country Link
US (5) US5422354A (xx)
EP (1) EP0540526B1 (xx)
JP (1) JP2514137B2 (xx)
CN (1) CN1058405A (xx)
AT (1) ATE116317T1 (xx)
AU (1) AU660416B2 (xx)
BR (1) BR9106665A (xx)
CA (1) CA2086434C (xx)
DE (1) DE69106365T2 (xx)
DK (1) DK0540526T3 (xx)
ES (1) ES2065691T3 (xx)
FI (1) FI114473B (xx)
GR (1) GR3015144T3 (xx)
HU (1) HUT62584A (xx)
IE (1) IE65000B1 (xx)
IL (1) IL98860A (xx)
MX (1) MX9100308A (xx)
MY (1) MY107157A (xx)
NO (1) NO302172B1 (xx)
NZ (1) NZ239063A (xx)
PL (1) PL167568B1 (xx)
PT (1) PT98393B (xx)
WO (1) WO1992001688A1 (xx)
YU (1) YU128091A (xx)
ZA (1) ZA915727B (xx)

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AU4396193A (en) * 1992-08-04 1994-03-03 Pfizer Inc. 3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
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US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
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FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
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GB9502582D0 (en) * 1995-02-10 1995-03-29 Smithkline Beecham Plc Novel process
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WO1997043286A1 (en) * 1996-05-13 1997-11-20 Zeneca Limited Bicyclic amines as insecticides
WO1998006720A1 (fr) * 1996-08-09 1998-02-19 Eisai Co., Ltd. Derives de benzopiperidine
GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
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US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
GB1527489A (en) * 1976-08-05 1978-10-04 Andreu Sa Dr Amine compound
US4246201A (en) * 1979-06-11 1981-01-20 Alfa Farmaceutici, S.P.A. Substituted N-(3-phenylthiopropyl)-3,3-diphenyl-propylamines possessing pharmacological activity
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
UA41251C2 (uk) * 1990-01-04 2001-09-17 Пфайзер, Інк. Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
CA2084193C (en) * 1990-06-01 1998-04-07 John A. Lowe, Iii 3-amino-2-aryl quinuclidines
US5422354A (en) * 1990-07-23 1995-06-06 Pfizer Inc Quinuclidine derivatives

Also Published As

Publication number Publication date
PT98393A (pt) 1992-05-29
IE65000B1 (en) 1995-10-04
IL98860A0 (en) 1992-07-15
DK0540526T3 (da) 1995-04-18
GR3015144T3 (en) 1995-05-31
PT98393B (pt) 1999-01-29
CN1058405A (zh) 1992-02-05
US5641786A (en) 1997-06-24
JP2514137B2 (ja) 1996-07-10
MX9100308A (es) 1992-02-28
WO1992001688A1 (en) 1992-02-06
JPH05507687A (ja) 1993-11-04
CA2086434A1 (en) 1992-01-24
ES2065691T3 (es) 1995-02-16
MY107157A (en) 1995-09-30
US5821248A (en) 1998-10-13
US5854256A (en) 1998-12-29
DE69106365D1 (de) 1995-02-09
AU660416B2 (en) 1995-06-29
AU7894891A (en) 1992-02-18
US5422354A (en) 1995-06-06
NO930222L (no) 1993-01-22
US5698568A (en) 1997-12-16
NO302172B1 (no) 1998-02-02
FI114473B (fi) 2004-10-29
IE912560A1 (en) 1992-01-29
YU128091A (sh) 1994-01-20
EP0540526A1 (en) 1993-05-12
PL167568B1 (pl) 1995-09-30
IL98860A (en) 1995-11-27
HUT62584A (en) 1993-05-28
BR9106665A (pt) 1993-06-08
EP0540526B1 (en) 1994-12-28
DE69106365T2 (de) 1995-05-04
CA2086434C (en) 1998-09-22
FI930262A (fi) 1993-01-22
FI930262A0 (fi) 1993-01-22
NO930222D0 (no) 1993-01-22
NZ239063A (en) 1995-09-26
HU9300188D0 (en) 1993-04-28
ATE116317T1 (de) 1995-01-15

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