ZA200905590B - Pleuromutilin derivatives for the treatment of diseases mediated by microbes - Google Patents
Pleuromutilin derivatives for the treatment of diseases mediated by microbesInfo
- Publication number
- ZA200905590B ZA200905590B ZA200905590A ZA200905590A ZA200905590B ZA 200905590 B ZA200905590 B ZA 200905590B ZA 200905590 A ZA200905590 A ZA 200905590A ZA 200905590 A ZA200905590 A ZA 200905590A ZA 200905590 B ZA200905590 B ZA 200905590B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- microbes
- treatment
- cycloalkyl
- diseases mediated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/61—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/93—Spiro compounds
- C07C2603/95—Spiro compounds containing "not free" spiro atoms
- C07C2603/98—Spiro compounds containing "not free" spiro atoms containing at least one ring with more than six ring members
- C07C2603/99—Spiro compounds containing "not free" spiro atoms containing at least one ring with more than six ring members containing eight-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07450053A EP1972618A1 (fr) | 2007-03-20 | 2007-03-20 | Dérivés de pleuromutilin pour le traitement des maladies médiées par des microbes |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200905590B true ZA200905590B (en) | 2010-10-27 |
Family
ID=38668870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200905590A ZA200905590B (en) | 2007-03-20 | 2008-03-19 | Pleuromutilin derivatives for the treatment of diseases mediated by microbes |
Country Status (32)
Country | Link |
---|---|
US (12) | US20090118366A1 (fr) |
EP (3) | EP1972618A1 (fr) |
JP (2) | JP5479114B2 (fr) |
KR (1) | KR101478593B1 (fr) |
CN (2) | CN101668738B (fr) |
AT (1) | ATE523486T1 (fr) |
AU (1) | AU2008229609B2 (fr) |
BR (1) | BRPI0809023B8 (fr) |
CA (1) | CA2678795C (fr) |
CY (2) | CY1117482T1 (fr) |
DK (2) | DK2380874T3 (fr) |
EA (1) | EA018707B1 (fr) |
ES (2) | ES2375503T3 (fr) |
FI (1) | FIC20200038I1 (fr) |
HK (1) | HK1140185A1 (fr) |
HR (1) | HRP20110869T1 (fr) |
HU (1) | HUS2100001I1 (fr) |
IL (1) | IL200440A (fr) |
LT (1) | LTPA2020531I1 (fr) |
MA (1) | MA31314B1 (fr) |
MY (1) | MY148916A (fr) |
NL (1) | NL301086I2 (fr) |
NO (1) | NO2021002I1 (fr) |
NZ (1) | NZ579011A (fr) |
PL (1) | PL2137143T3 (fr) |
PT (2) | PT2380874T (fr) |
SI (1) | SI2137143T1 (fr) |
TN (1) | TN2009000347A1 (fr) |
TW (1) | TWI406657B (fr) |
UA (1) | UA97836C2 (fr) |
WO (1) | WO2008113089A1 (fr) |
ZA (1) | ZA200905590B (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8092329B2 (en) | 2005-08-31 | 2012-01-10 | Wick Werks, LLC | Bicycle chain rings with ramps |
US8617015B2 (en) | 2005-09-27 | 2013-12-31 | Wick Werks, LLC | Bicycle chain rings |
EP1808431A1 (fr) * | 2006-01-16 | 2007-07-18 | Nabriva Therapeutics Forschungs GmbH | Dérivés de mutiline et leur utilisation en tant que composé pharmaceutique |
EP1972618A1 (fr) | 2007-03-20 | 2008-09-24 | Nabriva Therapeutics AG | Dérivés de pleuromutilin pour le traitement des maladies médiées par des microbes |
EP2159220A1 (fr) * | 2008-09-02 | 2010-03-03 | Nabriva Therapeutics AG | Composés organiques |
WO2010056855A1 (fr) * | 2008-11-13 | 2010-05-20 | Teva Pharmaceutical Industries Ltd. | Préparation de rétapamuline par l'intermédiaire de son précurseur pleuromutiline-thiol |
EP2399904A1 (fr) * | 2010-05-26 | 2011-12-28 | Nabriva Therapeutics AG | Procédé de préparation de pleuromutilines |
EP2390245A1 (fr) * | 2010-05-26 | 2011-11-30 | Nabriva Therapeutics AG | Amines énantiomériquement pures |
EP2433926A1 (fr) | 2010-09-09 | 2012-03-28 | Nabriva Therapeutics AG | Dérivés de pleuromutilin pour le traitement des maladies médiées par des microbes |
JP5906314B2 (ja) | 2011-07-15 | 2016-04-20 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | 2,3−ジフェニル−バレロニトリル誘導体、それらを製造する方法並びに除草剤及び植物成長調節剤としてのそれらの使用 |
CN103265487A (zh) * | 2013-06-05 | 2013-08-28 | 北京理工大学 | 截短侧耳素扩环衍生物及其制备方法和用途 |
CN104803911B (zh) * | 2014-01-23 | 2018-01-05 | 中国科学院上海药物研究所 | 一类截短侧耳素化合物、其药物组合物、合成方法与用途 |
ES2553929B1 (es) * | 2014-06-11 | 2016-09-26 | Antonio Javier MORENO CASTRO | Dispositivo de modificación/destrucción selectiva de tejidos orgánicos |
PL3310331T3 (pl) | 2015-06-17 | 2021-04-19 | Nabriva Therapeutics GmbH | Farmaceutyczne formulacje lefamuliny do iniekcji |
EA035651B1 (ru) | 2015-06-18 | 2020-07-22 | Эстетра Спрл | Диспергируемая в полости рта единица дозирования, содержащая эстетрольный компонент |
HUE049232T2 (hu) | 2015-06-18 | 2020-10-28 | Estetra Sprl | Esztetrol komponenst tartalmazó szájban diszpergálódó dózisegység |
TWI762573B (zh) | 2017-02-10 | 2022-05-01 | 奧地利商納畢瓦治療有限責任公司 | 截短側耳素之純化 |
JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
CN111170911A (zh) * | 2019-09-29 | 2020-05-19 | 安帝康(无锡)生物科技有限公司 | 用于治疗细菌感染性疾病的截短侧耳素类化合物 |
CN111170893B (zh) * | 2020-01-19 | 2022-04-26 | 郑州依米花手性药物研究有限公司 | Lefamulin的中间体化合物及其在Lefamulin制备中的应用 |
WO2021209173A1 (fr) | 2020-04-17 | 2021-10-21 | Nabriva Therapeutics GmbH | Nouvelle utilisation thérapeutique de pleuromutilines |
EP4135682A1 (fr) * | 2020-04-17 | 2023-02-22 | Nabriva Therapeutics GMBH | Utilisation thérapeutique de pleuromutilines |
EP4135683A1 (fr) | 2020-04-17 | 2023-02-22 | Nabriva Therapeutics GMBH | Utilisation thérapeutique de pleuromutilines |
EP4475834A1 (fr) | 2022-02-09 | 2024-12-18 | Nabriva Therapeutics GMBH | Léfamuline et ses dérivés pour utilisation dans le traitement contre une bactérie en forme de spirale |
EP4338732A1 (fr) | 2022-09-16 | 2024-03-20 | Nabriva Therapeutics GMBH | Lefamulin et ses dérivés pour leur utilisation dans le traitement de la tularémie |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4130709A (en) * | 1977-12-08 | 1978-12-19 | Eli Lilly And Company | Pleuromutilin glycoside derivatives |
DE4023848C2 (de) | 1990-07-27 | 1994-04-21 | Huels Chemische Werke Ag | Verfahren zur Herstellung von 3-C¶1¶- bis C¶6¶-Alkoxycarbonylcyclohexanpropionsäureestern |
GB9918037D0 (en) * | 1999-07-30 | 1999-09-29 | Biochemie Gmbh | Organic compounds |
GB0017031D0 (en) * | 2000-07-11 | 2000-08-30 | Biochemie Gmbh | Antimicrobials |
GB0207495D0 (en) | 2002-03-28 | 2002-05-08 | Biochemie Gmbh | Organic compounds |
GB0209262D0 (en) | 2002-04-23 | 2002-06-05 | Biochemie Gmbh | Organic compounds |
AU2003257493A1 (en) * | 2002-07-24 | 2004-02-16 | Sandoz Ag | Pleuromutilin derivatives as antimicrobbials |
GB0513058D0 (en) * | 2005-06-27 | 2005-08-03 | Sandoz Ag | Organic compounds |
EP1896404B1 (fr) * | 2005-06-27 | 2014-09-17 | Nabriva Therapeutics AG | Derives de la pleuromutiline contenant un groupe hydroxyamino- ou acyloxyaminocycloalkyle |
GB0515995D0 (en) * | 2005-08-03 | 2005-09-07 | Sandoz Ag | Organic compounds |
EP1972618A1 (fr) | 2007-03-20 | 2008-09-24 | Nabriva Therapeutics AG | Dérivés de pleuromutilin pour le traitement des maladies médiées par des microbes |
-
2007
- 2007-03-20 EP EP07450053A patent/EP1972618A1/fr not_active Withdrawn
- 2007-07-25 US US11/828,224 patent/US20090118366A1/en not_active Abandoned
-
2008
- 2008-03-19 CN CN200880007780.5A patent/CN101668738B/zh active Active
- 2008-03-19 EA EA200970868A patent/EA018707B1/ru unknown
- 2008-03-19 EP EP08714294A patent/EP2137143B1/fr active Active
- 2008-03-19 AT AT08714294T patent/ATE523486T1/de active
- 2008-03-19 CN CN201410406131.XA patent/CN104211624B/zh active Active
- 2008-03-19 WO PCT/AT2008/000097 patent/WO2008113089A1/fr active Application Filing
- 2008-03-19 NZ NZ579011A patent/NZ579011A/en unknown
- 2008-03-19 CA CA2678795A patent/CA2678795C/fr active Active
- 2008-03-19 PL PL08714294T patent/PL2137143T3/pl unknown
- 2008-03-19 PT PT110058633T patent/PT2380874T/pt unknown
- 2008-03-19 PT PT08714294T patent/PT2137143E/pt unknown
- 2008-03-19 ES ES08714294T patent/ES2375503T3/es active Active
- 2008-03-19 KR KR1020097018920A patent/KR101478593B1/ko active IP Right Grant
- 2008-03-19 JP JP2009553863A patent/JP5479114B2/ja active Active
- 2008-03-19 DK DK11005863.3T patent/DK2380874T3/en active
- 2008-03-19 MY MYPI20093722A patent/MY148916A/en unknown
- 2008-03-19 AU AU2008229609A patent/AU2008229609B2/en active Active
- 2008-03-19 UA UAA200910582A patent/UA97836C2/ru unknown
- 2008-03-19 DK DK08714294.9T patent/DK2137143T3/da active
- 2008-03-19 US US12/531,839 patent/US8071643B2/en active Active
- 2008-03-19 EP EP11005863.3A patent/EP2380874B1/fr active Active
- 2008-03-19 SI SI200830451T patent/SI2137143T1/sl unknown
- 2008-03-19 ES ES11005863.3T patent/ES2620459T3/es active Active
- 2008-03-19 BR BRPI0809023A patent/BRPI0809023B8/pt active IP Right Grant
- 2008-03-19 ZA ZA200905590A patent/ZA200905590B/xx unknown
- 2008-03-20 TW TW097109871A patent/TWI406657B/zh active
-
2009
- 2009-08-17 IL IL200440A patent/IL200440A/en active IP Right Grant
- 2009-08-19 TN TNP2009000347A patent/TN2009000347A1/fr unknown
- 2009-10-15 MA MA32283A patent/MA31314B1/fr unknown
-
2010
- 2010-06-25 HK HK10106270.6A patent/HK1140185A1/xx unknown
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2011
- 2011-10-04 US US13/252,732 patent/US8153689B2/en active Active
- 2011-11-22 HR HR20110869T patent/HRP20110869T1/hr unknown
- 2011-12-02 CY CY20111101198T patent/CY1117482T1/el unknown
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2012
- 2012-04-03 US US13/438,160 patent/US20130040954A1/en not_active Abandoned
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2014
- 2014-02-12 JP JP2014024500A patent/JP5893651B2/ja active Active
- 2014-05-21 US US14/283,734 patent/US20140256731A1/en not_active Abandoned
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2017
- 2017-04-06 US US15/480,756 patent/US20170266194A1/en not_active Abandoned
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2018
- 2018-06-29 US US16/023,880 patent/US20180303842A1/en not_active Abandoned
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2019
- 2019-02-15 US US16/277,143 patent/US20190175603A1/en not_active Abandoned
- 2019-10-04 US US16/593,449 patent/US20200030335A1/en not_active Abandoned
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2020
- 2020-05-22 US US16/881,117 patent/US20200281933A1/en not_active Abandoned
- 2020-09-16 CY CY2020032C patent/CY2020032I1/el unknown
- 2020-10-01 FI FIC20200038C patent/FIC20200038I1/fi unknown
- 2020-10-22 LT LTPA2020531C patent/LTPA2020531I1/lt unknown
- 2020-12-30 US US17/138,097 patent/US20210113571A1/en not_active Abandoned
-
2021
- 2021-01-04 NL NL301086C patent/NL301086I2/nl unknown
- 2021-01-12 HU HUS2100001C patent/HUS2100001I1/hu unknown
- 2021-01-15 NO NO2021002C patent/NO2021002I1/no unknown
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2022
- 2022-03-23 US US17/702,304 patent/US20220218713A1/en not_active Abandoned
Also Published As
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