ZA200904916B - N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase - Google Patents
N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenaseInfo
- Publication number
- ZA200904916B ZA200904916B ZA200904916A ZA200904916A ZA200904916B ZA 200904916 B ZA200904916 B ZA 200904916B ZA 200904916 A ZA200904916 A ZA 200904916A ZA 200904916 A ZA200904916 A ZA 200904916A ZA 200904916 B ZA200904916 B ZA 200904916B
- Authority
- ZA
- South Africa
- Prior art keywords
- inhibitors
- beta
- hydroxysteroid dehydrogenase
- benzamides
- adamantyl
- Prior art date
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- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/74—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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ES2393230T3 (es) * | 2007-04-24 | 2012-12-19 | High Point Pharmaceuticals, Llc | Uso farmacéutico de amidas sustituidas |
US8927549B2 (en) * | 2008-11-21 | 2015-01-06 | High Point Pharmaceuticals, Llc | Adamantyl benzamide derivatives |
-
2008
- 2008-02-19 EP EP08709090.8A patent/EP2150526B1/de active Active
- 2008-02-19 EA EA200970791A patent/EA016951B1/ru not_active IP Right Cessation
- 2008-02-19 CA CA2675669A patent/CA2675669C/en not_active Expired - Fee Related
- 2008-02-19 CN CN200880005896A patent/CN101679217A/zh active Pending
- 2008-02-19 US US12/528,229 patent/US8383820B2/en active Active
- 2008-02-19 WO PCT/EP2008/051971 patent/WO2008101914A2/en active Application Filing
- 2008-02-19 ZA ZA200904916A patent/ZA200904916B/xx unknown
- 2008-02-19 AU AU2008219326A patent/AU2008219326B2/en not_active Ceased
- 2008-02-19 MX MX2009008228A patent/MX2009008228A/es active IP Right Grant
- 2008-02-19 KR KR1020097017160A patent/KR101487813B1/ko active IP Right Grant
- 2008-02-19 BR BRPI0806847-0A patent/BRPI0806847A2/pt not_active IP Right Cessation
- 2008-02-19 JP JP2009550278A patent/JP5243455B2/ja not_active Expired - Fee Related
-
2009
- 2009-07-14 IL IL199853A patent/IL199853A/en active IP Right Grant
-
2013
- 2013-01-11 US US13/739,408 patent/US8809540B2/en not_active Expired - Fee Related
-
2014
- 2014-07-02 US US14/321,884 patent/US8907096B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2150526B1 (de) | 2017-09-20 |
MX2009008228A (es) | 2009-08-12 |
US8809540B2 (en) | 2014-08-19 |
US8383820B2 (en) | 2013-02-26 |
WO2008101914A3 (en) | 2009-01-15 |
KR101487813B1 (ko) | 2015-01-30 |
US20140315905A1 (en) | 2014-10-23 |
KR20090115730A (ko) | 2009-11-05 |
CA2675669C (en) | 2015-05-26 |
EA016951B1 (ru) | 2012-08-30 |
BRPI0806847A2 (pt) | 2014-04-29 |
CN101679217A (zh) | 2010-03-24 |
JP2010519243A (ja) | 2010-06-03 |
AU2008219326B2 (en) | 2012-12-13 |
WO2008101914A2 (en) | 2008-08-28 |
US20110039853A1 (en) | 2011-02-17 |
IL199853A (en) | 2015-02-26 |
CA2675669A1 (en) | 2008-08-28 |
EA200970791A1 (ru) | 2010-04-30 |
JP5243455B2 (ja) | 2013-07-24 |
EP2150526A2 (de) | 2010-02-10 |
AU2008219326A1 (en) | 2008-08-28 |
US20130231341A1 (en) | 2013-09-05 |
US8907096B2 (en) | 2014-12-09 |
IL199853A0 (en) | 2010-04-15 |
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