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ZA200801854B - Method of preparing esomeprazole and salts thereof - Google Patents

Method of preparing esomeprazole and salts thereof

Info

Publication number
ZA200801854B
ZA200801854B ZA200801854A ZA200801854A ZA200801854B ZA 200801854 B ZA200801854 B ZA 200801854B ZA 200801854 A ZA200801854 A ZA 200801854A ZA 200801854 A ZA200801854 A ZA 200801854A ZA 200801854 B ZA200801854 B ZA 200801854B
Authority
ZA
South Africa
Prior art keywords
salts
preparing esomeprazole
esomeprazole
preparing
Prior art date
Application number
ZA200801854A
Other languages
English (en)
Inventor
Ha Tae Hee
Kim Won Jeong
Oh Hee Sook
Park Chang Hee
Lee Jae Chul
Kim Han Kyong
Suh Kwee-Hyun
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of ZA200801854B publication Critical patent/ZA200801854B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200801854A 2005-07-28 2006-07-11 Method of preparing esomeprazole and salts thereof ZA200801854B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020050068761A KR100641534B1 (ko) 2005-07-28 2005-07-28 에스오메프라졸 및 그의 염의 제조방법

Publications (1)

Publication Number Publication Date
ZA200801854B true ZA200801854B (en) 2009-08-26

Family

ID=37621395

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200801854A ZA200801854B (en) 2005-07-28 2006-07-11 Method of preparing esomeprazole and salts thereof

Country Status (14)

Country Link
US (1) US7888511B2 (ja)
EP (1) EP1919897B1 (ja)
JP (1) JP4795435B2 (ja)
KR (1) KR100641534B1 (ja)
CN (1) CN101208330B (ja)
AU (1) AU2006273050B2 (ja)
BR (1) BRPI0613945A8 (ja)
CA (1) CA2616119C (ja)
IL (1) IL188600A (ja)
MX (1) MX2008000431A (ja)
NZ (1) NZ566271A (ja)
RU (1) RU2382777C2 (ja)
WO (1) WO2007013743A1 (ja)
ZA (1) ZA200801854B (ja)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2259269B1 (es) 2005-03-03 2007-11-01 Esteve Quimica, S.A. Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos.
CN101321746A (zh) * 2005-12-05 2008-12-10 阿斯利康(瑞典)有限公司 制备艾美拉唑非盐形式的新方法
AU2006331373B2 (en) 2005-12-28 2011-06-02 Union Quimico Farmaceutica, S.A. A process for the preparation of the (S)-enantiomer of omeprazole
AU2006345861B2 (en) * 2006-07-05 2012-07-12 Lupin Limited Process for the preparation of optically pure or optically enriched enantiomers of sulphoxide compounds
EP2152691B1 (en) * 2007-06-07 2011-11-23 Aurobindo Pharma Limited An improved process for preparing an optically active proton pump inhibitor
WO2009040825A1 (en) * 2007-09-25 2009-04-02 Hetero Drugs Limited A process for preparation of enantiomerically pure esomeprazole
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
CN101391993B (zh) * 2008-10-28 2012-07-04 安徽美诺华药物化学有限公司 通过与(s)-(-)-1,1'-联萘-2,2'-二酚形成包合配合物制备s-奥美拉唑及其盐的方法
WO2010058409A2 (en) 2008-11-18 2010-05-27 Hetero Research Foundation Optical purification of esomeprazole
WO2010072759A1 (en) * 2008-12-24 2010-07-01 Krka, Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of esomeprazole
WO2010097583A1 (en) 2009-02-24 2010-09-02 Cipla Limited Esomeprazole potassium polymorph and its preparation
WO2010118575A1 (en) * 2009-04-16 2010-10-21 Chengdu Organic Chemicals Co., Ltd, Chinese Academy Of Science Racemic enantiomers resoluting
WO2010148314A2 (en) * 2009-06-19 2010-12-23 Dr. Reddy's Laboratories Ltd. Preparation of esomeprazole and its pharmaceutically acceptable salts
CN101648943B (zh) * 2009-09-11 2013-05-15 南京工业大学 一种分离制备包结拆分后主客体中(s)-奥美拉唑的方法
US8420822B2 (en) * 2009-10-09 2013-04-16 Hetero Research Foundation Optical resolution of substituted 2-(2-pyridinylmethylsulphinyl)-1H-benzimidazoles
US8748619B2 (en) 2009-11-12 2014-06-10 Hetero Research Foundation Process for the resolution of omeprazole
EP2534144B1 (en) 2010-02-12 2014-09-03 Esteve Química, S.A. Preparation process of the sodium salt of Esomeprazole
CN104887673B (zh) * 2011-06-07 2017-12-29 成都国为生物医药有限公司 一种含埃索美拉唑钠的药物组合物及其制备方法
CN102850323A (zh) * 2011-06-30 2013-01-02 秦引林 一种埃索美拉唑钠的精制方法
CN102321072B (zh) * 2011-08-08 2013-07-03 天津市汉康医药生物技术有限公司 埃索美拉唑钠半水化合物
CN103145694B (zh) * 2011-12-06 2016-01-20 重庆煜澍丰医药有限公司 埃索美拉唑钠盐的晶体r及其制备方法和用途
CN103420979B (zh) * 2012-05-17 2016-04-20 广州莱泰制药有限公司 埃索美拉唑钠的精制方法
EP2980086B1 (en) 2014-07-29 2016-06-15 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Efficient process for the preparation of esomeprazole (S)-binol complex
CN104447737A (zh) * 2014-11-05 2015-03-25 沈阳化工大学 一种泰妥拉唑的手性拆分分离方法
CN107698515A (zh) * 2017-09-07 2018-02-16 拉萨泰达医药科技有限公司 一种苯并咪唑类络合物的制备方法
CN110526899A (zh) * 2018-05-24 2019-12-03 刘力 埃索美拉唑锶新化合物及其药物组合物和用途
WO2021039800A1 (ja) * 2019-08-29 2021-03-04 学校法人東京理科大学 スルホキシド化合物のエナンチオマー調製方法及びエナンチオマー調製システム

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002043D0 (sv) 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
SE510650C2 (sv) 1997-05-30 1999-06-14 Astra Ab Ny förening
CN1087739C (zh) * 1998-12-28 2002-07-17 中国科学院成都有机化学研究所 光学纯的苯并咪唑类抗消化性溃疡药物的包结拆分制备法
DE19951960C2 (de) 1999-10-28 2002-06-27 Gruenenthal Gmbh Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
WO2004002982A2 (en) * 2002-06-27 2004-01-08 Dr. Reddy's Laboratories Limited A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
ES2259269B1 (es) 2005-03-03 2007-11-01 Esteve Quimica, S.A. Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos.

Also Published As

Publication number Publication date
HK1118553A1 (en) 2009-02-13
EP1919897B1 (en) 2014-07-02
NZ566271A (en) 2010-01-29
EP1919897A4 (en) 2009-12-09
US20080194828A1 (en) 2008-08-14
BRPI0613945A8 (pt) 2016-06-07
RU2382777C2 (ru) 2010-02-27
WO2007013743A1 (en) 2007-02-01
CA2616119A1 (en) 2007-02-01
AU2006273050B2 (en) 2009-08-27
US7888511B2 (en) 2011-02-15
MX2008000431A (es) 2008-03-10
JP2009502906A (ja) 2009-01-29
IL188600A0 (en) 2008-04-13
IL188600A (en) 2011-12-29
KR100641534B1 (ko) 2006-11-01
EP1919897A1 (en) 2008-05-14
AU2006273050A1 (en) 2007-02-01
CA2616119C (en) 2010-05-18
CN101208330A (zh) 2008-06-25
CN101208330B (zh) 2010-12-22
JP4795435B2 (ja) 2011-10-19
BRPI0613945A2 (pt) 2011-02-22
RU2008107599A (ru) 2009-09-10

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