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ZA200808017B - Tetrahydropyridothienopyrimidine compounds and methods of use thereof - Google Patents

Tetrahydropyridothienopyrimidine compounds and methods of use thereof

Info

Publication number
ZA200808017B
ZA200808017B ZA200808017A ZA200808017A ZA200808017B ZA 200808017 B ZA200808017 B ZA 200808017B ZA 200808017 A ZA200808017 A ZA 200808017A ZA 200808017 A ZA200808017 A ZA 200808017A ZA 200808017 B ZA200808017 B ZA 200808017B
Authority
ZA
South Africa
Prior art keywords
tetrahydropyridothienopyrimidine
compounds
methods
tetrahydropyridothienopyrimidine compounds
Prior art date
Application number
ZA200808017A
Other languages
English (en)
Inventor
Zhang Chengzhi
Sidhu Kanwar
Lobell Mario
Ladouceur Gaetan
Zhao Qian
Liu Zheng
Kristen M Allegue
Chetan P Darne
Newcom Jason
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of ZA200808017B publication Critical patent/ZA200808017B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
ZA200808017A 2006-03-20 2008-09-18 Tetrahydropyridothienopyrimidine compounds and methods of use thereof ZA200808017B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78414606P 2006-03-20 2006-03-20

Publications (1)

Publication Number Publication Date
ZA200808017B true ZA200808017B (en) 2009-11-25

Family

ID=38523058

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200808017A ZA200808017B (en) 2006-03-20 2008-09-18 Tetrahydropyridothienopyrimidine compounds and methods of use thereof

Country Status (29)

Country Link
US (1) US8501755B2 (xx)
EP (1) EP2001890B1 (xx)
JP (1) JP5282026B2 (xx)
KR (1) KR20080110834A (xx)
CN (1) CN101448840B (xx)
AR (1) AR059901A1 (xx)
AT (1) ATE495179T1 (xx)
AU (1) AU2007227317A1 (xx)
BR (1) BRPI0711045A2 (xx)
CA (1) CA2647036C (xx)
CR (1) CR10304A (xx)
DE (1) DE602007011906D1 (xx)
DO (1) DOP2007000053A (xx)
EC (1) ECSP088749A (xx)
ES (1) ES2357654T3 (xx)
GT (1) GT200800187A (xx)
IL (1) IL194028A0 (xx)
MA (1) MA30351B1 (xx)
MX (1) MX2008012006A (xx)
NZ (1) NZ571326A (xx)
PA (1) PA8719401A1 (xx)
PE (1) PE20080144A1 (xx)
RU (1) RU2008141239A (xx)
SV (1) SV2008003032A (xx)
TN (1) TNSN08370A1 (xx)
TW (1) TW200804397A (xx)
UY (1) UY30220A1 (xx)
WO (1) WO2007109279A2 (xx)
ZA (1) ZA200808017B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
EP2212332B1 (en) * 2007-09-14 2012-10-24 Bayer Intellectual Property GmbH Substituted tricyclic compounds and methods of use thereof
CA2724726C (en) 2008-05-23 2018-02-27 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein inhibitor
JP5781934B2 (ja) * 2008-11-10 2015-09-24 ナショナル ヘルス リサーチ インスティテューツ チロシンキナーゼ阻害剤としての融合２環および３環ピリミジン化合物
JP2015513317A (ja) * 2012-01-25 2015-05-07 プロテオステイシス セラピューティクス，インコーポレイテッド プロテアソーム活性を増強する化合物
EP3149004A1 (en) * 2014-05-26 2017-04-05 Bayer Pharma Aktiengesellschaft Substituted tetrahydropyridothienopyrimidines
EP3111960B1 (en) * 2015-07-03 2019-12-11 Kyoto University Nuclear medicine diagnostic imaging agent
PE20190446A1 (es) 2016-06-22 2019-03-29 Univ Vanderbilt Moduladores alostericos positivos del receptor muscarinico de acetilcolina m4
US11008335B2 (en) 2016-11-07 2021-05-18 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
ES2892956T3 (es) 2016-11-07 2022-02-07 Univ Vanderbilt Moduladores alostéricos positivos del receptor muscarínico de acetilcolina M4
CN109862893B (zh) 2016-11-07 2023-02-17 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
CN111406058A (zh) 2017-12-05 2020-07-10 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
US20220177488A1 (en) * 2019-03-19 2022-06-09 Suvalent Therapeutics, Inc. Sumo inhibitor compounds and uses thereof
CN117980309A (zh) * 2021-08-05 2024-05-03 百时美施贵宝公司 用作her2抑制剂的三环稠合嘧啶化合物
CN114736154B (zh) * 2022-03-15 2023-07-21 安庆朗坤药业有限公司 N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3453900A (en) * 1999-03-30 2000-10-23 Nippon Soda Co., Ltd. Thienopyrimidine compounds and salts thereof and process for the preparation of the same
DE19944604A1 (de) * 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
US6608053B2 (en) 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
WO2003035653A1 (fr) * 2001-10-26 2003-05-01 Nippon Soda Co.,Ltd. Compose pyridothienopyrimidine et son sel
ES2280040T3 (es) * 2003-07-24 2007-09-01 Bayer Pharmaceuticals Corporation Compuestos de tetrahidrobenzotienopirimidinamina sustituidos utiles para tratar trastornos hiperproliferativos.

Also Published As

Publication number Publication date
JP5282026B2 (ja) 2013-09-04
EP2001890B1 (en) 2011-01-12
CR10304A (es) 2009-01-27
IL194028A0 (en) 2009-09-22
MX2008012006A (es) 2008-10-03
WO2007109279A2 (en) 2007-09-27
EP2001890A2 (en) 2008-12-17
WO2007109279A3 (en) 2007-12-21
ATE495179T1 (de) 2011-01-15
DE602007011906D1 (de) 2011-02-24
TW200804397A (en) 2008-01-16
CA2647036C (en) 2015-06-23
CA2647036A1 (en) 2007-09-27
NZ571326A (en) 2011-07-29
RU2008141239A (ru) 2010-04-27
GT200800187A (es) 2009-04-07
KR20080110834A (ko) 2008-12-19
DOP2007000053A (es) 2007-09-30
US20100298297A1 (en) 2010-11-25
TNSN08370A1 (en) 2009-12-29
PE20080144A1 (es) 2008-04-06
JP2009530387A (ja) 2009-08-27
AU2007227317A1 (en) 2007-09-27
CN101448840B (zh) 2011-12-14
UY30220A1 (es) 2007-10-31
SV2008003032A (es) 2009-11-26
CN101448840A (zh) 2009-06-03
ES2357654T3 (es) 2011-04-28
US8501755B2 (en) 2013-08-06
AR059901A1 (es) 2008-05-07
ECSP088749A (es) 2008-10-31
PA8719401A1 (es) 2009-02-09
MA30351B1 (fr) 2009-04-01
BRPI0711045A2 (pt) 2012-06-26

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