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UY30220A1 - Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo - Google Patents

Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo

Info

Publication number
UY30220A1
UY30220A1 UY30220A UY30220A UY30220A1 UY 30220 A1 UY30220 A1 UY 30220A1 UY 30220 A UY30220 A UY 30220A UY 30220 A UY30220 A UY 30220A UY 30220 A1 UY30220 A1 UY 30220A1
Authority
UY
Uruguay
Prior art keywords
compounds
methods
tetrahydropiridotienopirimidina
pharmaceutical compositions
disorders
Prior art date
Application number
UY30220A
Other languages
English (en)
Inventor
Chetan Darne
Kristin Allegue
Kanwar Sidhu
Zheng Liu
Jason Newcom
Dr Mario Lobell
Qian Zhao
Gaetan H Ladouceur
Chengzhi Zhang
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of UY30220A1 publication Critical patent/UY30220A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invencion se relaciona con compuestos de la formula (I) en la cual las variables son las descriptas en la memoria descriptiva, con composiciones farmacéuticas que los contienen, con métodos para la preparacion de los compuestos y composiciones farmacéuticas para el tratamiento o prevencion de trastornos, en particular el cáncer.
UY30220A 2006-03-20 2007-03-19 Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo UY30220A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78414606P 2006-03-20 2006-03-20

Publications (1)

Publication Number Publication Date
UY30220A1 true UY30220A1 (es) 2007-10-31

Family

ID=38523058

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30220A UY30220A1 (es) 2006-03-20 2007-03-19 Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo

Country Status (29)

Country Link
US (1) US8501755B2 (es)
EP (1) EP2001890B1 (es)
JP (1) JP5282026B2 (es)
KR (1) KR20080110834A (es)
CN (1) CN101448840B (es)
AR (1) AR059901A1 (es)
AT (1) ATE495179T1 (es)
AU (1) AU2007227317A1 (es)
BR (1) BRPI0711045A2 (es)
CA (1) CA2647036C (es)
CR (1) CR10304A (es)
DE (1) DE602007011906D1 (es)
DO (1) DOP2007000053A (es)
EC (1) ECSP088749A (es)
ES (1) ES2357654T3 (es)
GT (1) GT200800187A (es)
IL (1) IL194028A0 (es)
MA (1) MA30351B1 (es)
MX (1) MX2008012006A (es)
NZ (1) NZ571326A (es)
PA (1) PA8719401A1 (es)
PE (1) PE20080144A1 (es)
RU (1) RU2008141239A (es)
SV (1) SV2008003032A (es)
TN (1) TNSN08370A1 (es)
TW (1) TW200804397A (es)
UY (1) UY30220A1 (es)
WO (1) WO2007109279A2 (es)
ZA (1) ZA200808017B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US8524722B2 (en) * 2007-09-14 2013-09-03 Bayer Intellectual Property Gmbh Substituted tricyclic compounds and methods of use thereof
EA019819B1 (ru) 2008-05-23 2014-06-30 ПАНМИРА ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Кристаллическая полиморфная форма с ингибитора белка, активирующего 5-липоксигеназу, фармацевтическая композиция на ее основе и применение в лечении
KR101703941B1 (ko) 2008-11-10 2017-02-07 내셔날 헬스 리서치 인스티튜트 티로신 키나아제 억제제로서의 접합 이환 및 삼환 피리미딘 화합물
EP2806876A4 (en) * 2012-01-25 2016-03-02 Proteostasis Therapeutics Inc COMPOUNDS ENHANCING THE ACTIVITY OF PROTEASOMES
JP2017519737A (ja) * 2014-05-26 2017-07-20 バイエル・ファルマ・アクティエンゲゼルシャフト 置換テトラヒドロピリドチエノピリミジン
EP3111960B1 (en) * 2015-07-03 2019-12-11 Kyoto University Nuclear medicine diagnostic imaging agent
EP4186910A1 (en) 2016-06-22 2023-05-31 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m4
BR112018013879A2 (pt) 2016-11-07 2018-12-11 Univ Vanderbilt moduladores alostéricos positivos do receptor muscarínico de acetilcolina m4
MA46722A (fr) 2016-11-07 2019-09-11 Univ Vanderbilt Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4
CN109862893B (zh) 2016-11-07 2023-02-17 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
US11376254B2 (en) 2017-12-05 2022-07-05 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
US20220177488A1 (en) * 2019-03-19 2022-06-09 Suvalent Therapeutics, Inc. Sumo inhibitor compounds and uses thereof
WO2023015240A1 (en) * 2021-08-05 2023-02-09 Bristol-Myers Squibb Company Tricyclic fused pyrimidine compounds for use as her2 inhibitors
CN114736154B (zh) * 2022-03-15 2023-07-21 安庆朗坤药业有限公司 N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1323719A1 (en) * 1999-03-30 2003-07-02 Nippon Soda Co., Ltd. Thienopyrimidine compounds and salts thereof and process for the preparation of the same
DE19944604A1 (de) 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
WO2003035653A1 (fr) * 2001-10-26 2003-05-01 Nippon Soda Co.,Ltd. Compose pyridothienopyrimidine et son sel
EP1651652B1 (en) 2003-07-24 2006-12-27 Bayer Pharmaceuticals Corporation Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders

Also Published As

Publication number Publication date
TW200804397A (en) 2008-01-16
RU2008141239A (ru) 2010-04-27
DE602007011906D1 (de) 2011-02-24
NZ571326A (en) 2011-07-29
ES2357654T3 (es) 2011-04-28
CN101448840B (zh) 2011-12-14
GT200800187A (es) 2009-04-07
US8501755B2 (en) 2013-08-06
PE20080144A1 (es) 2008-04-06
EP2001890A2 (en) 2008-12-17
DOP2007000053A (es) 2007-09-30
BRPI0711045A2 (pt) 2012-06-26
AR059901A1 (es) 2008-05-07
ZA200808017B (en) 2009-11-25
US20100298297A1 (en) 2010-11-25
MX2008012006A (es) 2008-10-03
ATE495179T1 (de) 2011-01-15
CA2647036A1 (en) 2007-09-27
JP2009530387A (ja) 2009-08-27
IL194028A0 (en) 2009-09-22
ECSP088749A (es) 2008-10-31
EP2001890B1 (en) 2011-01-12
KR20080110834A (ko) 2008-12-19
CA2647036C (en) 2015-06-23
AU2007227317A1 (en) 2007-09-27
JP5282026B2 (ja) 2013-09-04
MA30351B1 (fr) 2009-04-01
WO2007109279A3 (en) 2007-12-21
CR10304A (es) 2009-01-27
CN101448840A (zh) 2009-06-03
PA8719401A1 (es) 2009-02-09
WO2007109279A2 (en) 2007-09-27
SV2008003032A (es) 2009-11-26
TNSN08370A1 (en) 2009-12-29

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170608