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ZA200606724B - Derivatives of heteroaryl-alkylcarbamates, preparation method thereof and use of same as FAAH enzyme inhibitors - Google Patents

Derivatives of heteroaryl-alkylcarbamates, preparation method thereof and use of same as FAAH enzyme inhibitors

Info

Publication number
ZA200606724B
ZA200606724B ZA200606724A ZA200606724A ZA200606724B ZA 200606724 B ZA200606724 B ZA 200606724B ZA 200606724 A ZA200606724 A ZA 200606724A ZA 200606724 A ZA200606724 A ZA 200606724A ZA 200606724 B ZA200606724 B ZA 200606724B
Authority
ZA
South Africa
Prior art keywords
alkylcarbamates
heteroaryl
derivatives
preparation
same
Prior art date
Application number
ZA200606724A
Other languages
English (en)
Inventor
Abouabdellah Ahmed
Bartsch-Li Rugine
Hoornaert Christian
Ravet Antoine
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ZA200606724B publication Critical patent/ZA200606724B/xx

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
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ZA200606724A 2004-02-26 2005-02-25 Derivatives of heteroaryl-alkylcarbamates, preparation method thereof and use of same as FAAH enzyme inhibitors ZA200606724B (en)

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KR101799429B1 (ko) * 2010-05-03 2017-11-21 에스케이바이오팜 주식회사 신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물

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FR2866886B1 (fr) 2007-08-31
AR047973A1 (es) 2006-03-15
US20070021426A1 (en) 2007-01-25
CN1926097B (zh) 2011-06-08
TW200533637A (en) 2005-10-16
IL177329A0 (en) 2006-12-10
US20110237595A1 (en) 2011-09-29
BRPI0508193A (pt) 2007-08-14
SI1720829T1 (sl) 2010-02-26
US7645757B2 (en) 2010-01-12
ATE445592T1 (de) 2009-10-15
NZ550008A (en) 2010-06-25
IL177329A (en) 2012-01-31
ES2334449T3 (es) 2010-03-10
FR2866886A1 (fr) 2005-09-02
DE602005017122D1 (de) 2009-11-26
NO20064329L (no) 2006-09-25
PL1720829T3 (pl) 2010-03-31
CA2554609A1 (fr) 2005-09-29
EP2251324A1 (fr) 2010-11-17
KR20070011297A (ko) 2007-01-24
WO2005090292A1 (fr) 2005-09-29
JP4824668B2 (ja) 2011-11-30
EP1720829A1 (fr) 2006-11-15
AU2005223423A1 (en) 2005-09-29
RU2006134026A (ru) 2008-04-10
PT1720829E (pt) 2010-01-13
HK1101759A1 (en) 2007-10-26
HRP20100017T1 (hr) 2010-02-28
AU2005223423B2 (en) 2011-04-14
RU2364586C2 (ru) 2009-08-20
DK1720829T3 (da) 2010-03-01
CY1109716T1 (el) 2014-08-13
RS51246B (sr) 2010-12-31
JP2007524705A (ja) 2007-08-30
CN1926097A (zh) 2007-03-07
US20100069405A1 (en) 2010-03-18
MA28367A1 (fr) 2006-12-01
EP1720829B1 (fr) 2009-10-14

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