ZA200302633B - 2-Guianidino-4-arylquinazolines. - Google Patents
2-Guianidino-4-arylquinazolines. Download PDFInfo
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- ZA200302633B ZA200302633B ZA200302633A ZA200302633A ZA200302633B ZA 200302633 B ZA200302633 B ZA 200302633B ZA 200302633 A ZA200302633 A ZA 200302633A ZA 200302633 A ZA200302633 A ZA 200302633A ZA 200302633 B ZA200302633 B ZA 200302633B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10043667A DE10043667A1 (de) | 2000-09-05 | 2000-09-05 | 2-Guanidino-4-aryl-chinazoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200302633B true ZA200302633B (en) | 2004-09-08 |
Family
ID=7655015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200302633A ZA200302633B (en) | 2000-09-05 | 2003-04-03 | 2-Guianidino-4-arylquinazolines. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20040039001A1 (ko) |
| EP (1) | EP1315704A1 (ko) |
| JP (1) | JP2004508360A (ko) |
| KR (1) | KR20030062404A (ko) |
| CN (1) | CN1450996A (ko) |
| AU (1) | AU2001285886A1 (ko) |
| BR (1) | BR0113583A (ko) |
| CA (1) | CA2421222A1 (ko) |
| CZ (1) | CZ2003858A3 (ko) |
| DE (1) | DE10043667A1 (ko) |
| MX (1) | MXPA03001877A (ko) |
| NO (1) | NO20030999D0 (ko) |
| PL (1) | PL360391A1 (ko) |
| RU (1) | RU2003108861A (ko) |
| WO (1) | WO2002020496A1 (ko) |
| ZA (1) | ZA200302633B (ko) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10163992A1 (de) * | 2001-12-24 | 2003-07-03 | Merck Patent Gmbh | 4-Aryl-chinazoline |
| DE10304374A1 (de) | 2003-02-04 | 2004-08-05 | Aventis Pharma Deutschland Gmbh | Neue substituierte 2-Aminoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US20050054705A1 (en) | 2003-02-04 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
| WO2009046448A1 (en) * | 2007-10-04 | 2009-04-09 | Intellikine, Inc. | Chemical entities and therapeutic uses thereof |
| JP5502106B2 (ja) | 2008-12-31 | 2014-05-28 | アーデリクス，インコーポレーテッド | 体液貯留または塩分過負荷と関連する障害および消化管障害の治療におけるｎｈｅ媒介性アンチポートを阻害するための組成物および方法 |
| WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| US20120088737A2 (en) * | 2009-10-02 | 2012-04-12 | Ajinomoto Co., Inc | Novel acyl guanidine derivatives |
| AP3849A (en) | 2011-12-15 | 2016-09-30 | Novartis Ag | Use of inhibitors of the activity or function of pi3k |
| US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| KR102138390B1 (ko) | 2012-08-21 | 2020-07-27 | 알데릭스, 인코포레이티드 | 체액 저류 또는 염 과부하와 연관된 장애 및 위장관 장애의 치료에서 ｎｈｅ-매개된 역수송 저해를 위한 화합물 및 방법 |
| RS58969B1 (sr) | 2013-04-12 | 2019-08-30 | Ardelyx Inc | Jedinjenja koja se vezuju za nhe3 i postupci za inhibiranje transporta fosfata |
| BR112019013956A2 (pt) | 2017-01-09 | 2020-02-11 | Ardelyx, Inc. | Compostos úteis para tratar distúrbios do trato gastrointestinal |
| MA47203A (fr) | 2017-01-09 | 2019-11-13 | Ardelyx Inc | Inhibiteurs d'antiport à médiation par nhe |
| SG11202000950TA (en) | 2017-08-04 | 2020-02-27 | Ardelyx Inc | Glycyrrhetinic acid derivatives for treating hyperkalemia |
| EP4234016A3 (en) | 2019-02-07 | 2023-10-18 | Ardelyx, Inc. | Glycyrrhetinic acid derivatives for use in treating hyperkalemia |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3131187A (en) * | 1964-04-28 | Certain z-guantoino-x-aryl-quinazolines | ||
| JPH11209350A (ja) * | 1998-01-26 | 1999-08-03 | Eisai Co Ltd | 含窒素複素環誘導体およびその医薬 |
| DE10019062A1 (de) * | 2000-04-18 | 2001-10-25 | Merck Patent Gmbh | 2-Guanidino-4-aryl-chinazoline als NHE-3 Inhibitoren |
| US20030139431A1 (en) * | 2001-09-24 | 2003-07-24 | Kawakami Joel K. | Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors |
| DE10163992A1 (de) * | 2001-12-24 | 2003-07-03 | Merck Patent Gmbh | 4-Aryl-chinazoline |
-
2000
- 2000-09-05 DE DE10043667A patent/DE10043667A1/de not_active Withdrawn
-
2001
- 2001-08-13 MX MXPA03001877A patent/MXPA03001877A/es unknown
- 2001-08-13 WO PCT/EP2001/009325 patent/WO2002020496A1/de not_active Application Discontinuation
- 2001-08-13 CN CN01815093A patent/CN1450996A/zh active Pending
- 2001-08-13 CA CA002421222A patent/CA2421222A1/en not_active Abandoned
- 2001-08-13 RU RU2003108861/04A patent/RU2003108861A/ru not_active Application Discontinuation
- 2001-08-13 US US10/363,169 patent/US20040039001A1/en not_active Abandoned
- 2001-08-13 KR KR10-2003-7002570A patent/KR20030062404A/ko not_active Application Discontinuation
- 2001-08-13 EP EP01965191A patent/EP1315704A1/de not_active Withdrawn
- 2001-08-13 AU AU2001285886A patent/AU2001285886A1/en not_active Abandoned
- 2001-08-13 PL PL36039101A patent/PL360391A1/xx unknown
- 2001-08-13 JP JP2002525118A patent/JP2004508360A/ja active Pending
- 2001-08-13 BR BR0113583-0A patent/BR0113583A/pt not_active Application Discontinuation
- 2001-08-13 CZ CZ2003858A patent/CZ2003858A3/cs unknown
-
2003
- 2003-03-04 NO NO20030999A patent/NO20030999D0/no not_active Application Discontinuation
- 2003-04-03 ZA ZA200302633A patent/ZA200302633B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE10043667A1 (de) | 2002-03-14 |
| KR20030062404A (ko) | 2003-07-25 |
| CA2421222A1 (en) | 2003-03-03 |
| NO20030999D0 (no) | 2003-03-04 |
| BR0113583A (pt) | 2003-07-15 |
| US20040039001A1 (en) | 2004-02-26 |
| RU2003108861A (ru) | 2004-09-20 |
| CZ2003858A3 (cs) | 2003-06-18 |
| EP1315704A1 (de) | 2003-06-04 |
| CN1450996A (zh) | 2003-10-22 |
| MXPA03001877A (es) | 2003-06-24 |
| WO2002020496A1 (de) | 2002-03-14 |
| JP2004508360A (ja) | 2004-03-18 |
| AU2001285886A1 (en) | 2002-03-22 |
| PL360391A1 (en) | 2004-09-06 |
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