ZA200108905B - Use of macrolide compounds for the treatment of dry eye. - Google Patents
Use of macrolide compounds for the treatment of dry eye.Info
- Publication number
- ZA200108905B ZA200108905B ZA200108905A ZA200108905A ZA200108905B ZA 200108905 B ZA200108905 B ZA 200108905B ZA 200108905 A ZA200108905 A ZA 200108905A ZA 200108905 A ZA200108905 A ZA 200108905A ZA 200108905 B ZA200108905 B ZA 200108905B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- dry eye
- macrolide compounds
- macrolide
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13200999P | 1999-04-30 | 1999-04-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200108905B true ZA200108905B (en) | 2002-12-24 |
Family
ID=22452015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200108905A ZA200108905B (en) | 1999-04-30 | 2001-10-29 | Use of macrolide compounds for the treatment of dry eye. |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1173177B2 (xx) |
JP (2) | JP5036934B2 (xx) |
KR (1) | KR20020015316A (xx) |
CN (1) | CN1190194C (xx) |
AR (1) | AR023807A1 (xx) |
AT (1) | ATE281167T1 (xx) |
AU (1) | AU777915B2 (xx) |
BR (1) | BR0011225A (xx) |
CA (1) | CA2372448A1 (xx) |
CZ (1) | CZ20013769A3 (xx) |
DE (1) | DE60015516T2 (xx) |
ES (1) | ES2232439T3 (xx) |
HK (2) | HK1043321B (xx) |
HU (1) | HUP0200864A3 (xx) |
IL (1) | IL146162A0 (xx) |
MX (1) | MXPA01010988A (xx) |
NO (1) | NO20015288D0 (xx) |
NZ (1) | NZ515339A (xx) |
PT (1) | PT1173177E (xx) |
TR (1) | TR200103119T2 (xx) |
TW (1) | TWI230066B (xx) |
WO (1) | WO2000066122A1 (xx) |
ZA (1) | ZA200108905B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60015516T2 (de) * | 1999-04-30 | 2005-12-01 | Sucampo Ag | Verwendung von makroliden zur behandlung von trockenen augen |
US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
JP2005502621A (ja) | 2001-07-06 | 2005-01-27 | スキャンポ アーゲー | インターロイキン2阻害剤および抗菌剤を含む局所投与用組成物 |
AR038628A1 (es) * | 2002-03-04 | 2005-01-19 | Novartis Ag | Composicion oftalmica |
CA2495103A1 (en) * | 2002-08-09 | 2004-02-19 | Sucampo Pharmaceuticals, Inc. | Pharmaceutical compositions comprising fk506 derivatives and their use for the treatment of allergic diseases |
US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US20040198763A1 (en) * | 2003-01-16 | 2004-10-07 | Sucampo Ag | Method of treating dry eye with a macrolide compound |
US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
US7083802B2 (en) * | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US7083803B2 (en) | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
WO2005032534A1 (ja) | 2003-10-06 | 2005-04-14 | Ophtecs Corporation | 涙液異常の治療のための眼科用組成物 |
EP3025713A1 (en) | 2005-02-09 | 2016-06-01 | Santen Pharmaceutical Co., Ltd | Liquid formulations for treatment of diseases or conditions |
WO2007011880A2 (en) | 2005-07-18 | 2007-01-25 | Minu, L.L.C. | Enhanced ocular neuroprotection/neurostimulation |
BRPI0707612B8 (pt) | 2006-02-09 | 2021-05-25 | Macusight Inc | vaso lacrado e formulações líquidas contidas no mesmo |
CA2645488C (en) | 2006-03-23 | 2014-09-02 | Macusight, Inc. | Formulations comprising rapamycin and methods using same for vascular permeability-related diseases or conditions |
EP2335735A1 (en) * | 2009-12-14 | 2011-06-22 | Novaliq GmbH | Pharmaceutical composition for treatment of dry eye syndrome |
KR20200069261A (ko) * | 2017-05-30 | 2020-06-16 | 엑시모어 엘티디. | 항생제 마크로라이드를 전달하는 안구건조증을 치료하기 위한 조성물 및 방법 |
WO2019060696A1 (en) | 2017-09-25 | 2019-03-28 | Surface Pharmaceuticals, Inc. | OPTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR SURFACE DISEASE |
US12070442B2 (en) | 2018-12-27 | 2024-08-27 | Surface Ophthalmics, Inc. | Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA905202B (en) * | 1989-07-05 | 1991-04-24 | Fujisawa Pharmaceutical Co | Aqueous liquid composition for external use |
US5514686A (en) * | 1991-04-26 | 1996-05-07 | Fujisawa Pharmaceutical Co., Ltd. | Use of macrolide compounds for eye diseases |
ZA924953B (en) * | 1991-07-25 | 1993-04-28 | Univ Louisville Res Found | Method of treating ocular inflammation |
AR004480A1 (es) * | 1995-04-06 | 1998-12-16 | Amico Derin C D | Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen |
GB9601120D0 (en) * | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
WO1999051215A2 (en) * | 1998-04-06 | 1999-10-14 | Fujisawa Pharmaceutical Co., Ltd. | Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins |
KR100406823B1 (ko) * | 1998-04-27 | 2003-11-21 | 후지사와 야꾸힝 고교 가부시키가이샤 | 의약 조성물 |
US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
DE60015516T2 (de) * | 1999-04-30 | 2005-12-01 | Sucampo Ag | Verwendung von makroliden zur behandlung von trockenen augen |
-
2000
- 2000-04-26 DE DE60015516T patent/DE60015516T2/de not_active Expired - Lifetime
- 2000-04-26 IL IL14616200A patent/IL146162A0/xx unknown
- 2000-04-26 WO PCT/JP2000/002756 patent/WO2000066122A1/en not_active Application Discontinuation
- 2000-04-26 CA CA002372448A patent/CA2372448A1/en not_active Abandoned
- 2000-04-26 CZ CZ20013769A patent/CZ20013769A3/cs unknown
- 2000-04-26 JP JP2000615007A patent/JP5036934B2/ja not_active Expired - Fee Related
- 2000-04-26 CN CNB008067686A patent/CN1190194C/zh not_active Expired - Fee Related
- 2000-04-26 TR TR2001/03119T patent/TR200103119T2/xx unknown
- 2000-04-26 AU AU41429/00A patent/AU777915B2/en not_active Ceased
- 2000-04-26 KR KR1020017013768A patent/KR20020015316A/ko not_active Application Discontinuation
- 2000-04-26 TW TW089107899A patent/TWI230066B/zh not_active IP Right Cessation
- 2000-04-26 NZ NZ515339A patent/NZ515339A/xx unknown
- 2000-04-26 EP EP00921047.7A patent/EP1173177B2/en not_active Expired - Lifetime
- 2000-04-26 BR BR0011225-9A patent/BR0011225A/pt not_active IP Right Cessation
- 2000-04-26 AT AT00921047T patent/ATE281167T1/de active
- 2000-04-26 ES ES00921047T patent/ES2232439T3/es not_active Expired - Lifetime
- 2000-04-26 HU HU0200864A patent/HUP0200864A3/hu unknown
- 2000-04-26 MX MXPA01010988A patent/MXPA01010988A/es active IP Right Grant
- 2000-04-26 PT PT00921047T patent/PT1173177E/pt unknown
- 2000-04-28 AR ARP000102060A patent/AR023807A1/es not_active Application Discontinuation
-
2001
- 2001-10-29 NO NO20015288A patent/NO20015288D0/no not_active Application Discontinuation
- 2001-10-29 ZA ZA200108905A patent/ZA200108905B/xx unknown
-
2002
- 2002-07-12 HK HK02105192.3A patent/HK1043321B/zh not_active IP Right Cessation
- 2002-10-24 HK HK02107726.4A patent/HK1046099A1/zh unknown
-
2012
- 2012-02-03 JP JP2012022420A patent/JP2012116857A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1173177B1 (en) | 2004-11-03 |
CA2372448A1 (en) | 2000-11-09 |
AU4142900A (en) | 2000-11-17 |
TWI230066B (en) | 2005-04-01 |
AR023807A1 (es) | 2002-09-04 |
NZ515339A (en) | 2004-02-27 |
WO2000066122A1 (en) | 2000-11-09 |
MXPA01010988A (es) | 2004-04-21 |
IL146162A0 (en) | 2002-07-25 |
AU777915B2 (en) | 2004-11-04 |
HUP0200864A3 (en) | 2004-07-28 |
CZ20013769A3 (cs) | 2002-03-13 |
HUP0200864A2 (hu) | 2002-07-29 |
BR0011225A (pt) | 2002-03-19 |
CN1190194C (zh) | 2005-02-23 |
HK1043321A1 (en) | 2002-09-13 |
CN1353608A (zh) | 2002-06-12 |
DE60015516D1 (de) | 2004-12-09 |
PT1173177E (pt) | 2005-03-31 |
EP1173177A1 (en) | 2002-01-23 |
JP2012116857A (ja) | 2012-06-21 |
JP2002543132A (ja) | 2002-12-17 |
DE60015516T2 (de) | 2005-12-01 |
TR200103119T2 (tr) | 2002-04-22 |
EP1173177B2 (en) | 2014-03-05 |
ES2232439T3 (es) | 2005-06-01 |
NO20015288L (no) | 2001-10-29 |
NO20015288D0 (no) | 2001-10-29 |
JP5036934B2 (ja) | 2012-09-26 |
ATE281167T1 (de) | 2004-11-15 |
KR20020015316A (ko) | 2002-02-27 |
HK1043321B (zh) | 2005-07-15 |
HK1046099A1 (zh) | 2002-12-27 |
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