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HK1043321B - 應用大環內酯化合物治療乾眼癥 - Google Patents

應用大環內酯化合物治療乾眼癥

Info

Publication number
HK1043321B
HK1043321B HK02105192.3A HK02105192A HK1043321B HK 1043321 B HK1043321 B HK 1043321B HK 02105192 A HK02105192 A HK 02105192A HK 1043321 B HK1043321 B HK 1043321B
Authority
HK
Hong Kong
Prior art keywords
treatment
dry eye
macrolide compounds
macrolide
compounds
Prior art date
Application number
HK02105192.3A
Other languages
English (en)
Other versions
HK1043321A1 (en
Inventor
Ueno Ryuji
Original Assignee
蘇坎波公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22452015&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1043321(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 蘇坎波公司 filed Critical 蘇坎波公司
Publication of HK1043321A1 publication Critical patent/HK1043321A1/xx
Publication of HK1043321B publication Critical patent/HK1043321B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
HK02105192.3A 1999-04-30 2002-07-12 應用大環內酯化合物治療乾眼癥 HK1043321B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13200999P 1999-04-30 1999-04-30
PCT/JP2000/002756 WO2000066122A1 (en) 1999-04-30 2000-04-26 Use of macrolide compounds for the treatment of dry eye

Publications (2)

Publication Number Publication Date
HK1043321A1 HK1043321A1 (en) 2002-09-13
HK1043321B true HK1043321B (zh) 2005-07-15

Family

ID=22452015

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02105192.3A HK1043321B (zh) 1999-04-30 2002-07-12 應用大環內酯化合物治療乾眼癥
HK02107726.4A HK1046099A1 (zh) 1999-04-30 2002-10-24 用於治療乾眼的大環內酯化合物的應用

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK02107726.4A HK1046099A1 (zh) 1999-04-30 2002-10-24 用於治療乾眼的大環內酯化合物的應用

Country Status (23)

Country Link
EP (1) EP1173177B2 (zh)
JP (2) JP5036934B2 (zh)
KR (1) KR20020015316A (zh)
CN (1) CN1190194C (zh)
AR (1) AR023807A1 (zh)
AT (1) ATE281167T1 (zh)
AU (1) AU777915B2 (zh)
BR (1) BR0011225A (zh)
CA (1) CA2372448A1 (zh)
CZ (1) CZ20013769A3 (zh)
DE (1) DE60015516T2 (zh)
ES (1) ES2232439T3 (zh)
HK (2) HK1043321B (zh)
HU (1) HUP0200864A3 (zh)
IL (1) IL146162A0 (zh)
MX (1) MXPA01010988A (zh)
NO (1) NO20015288D0 (zh)
NZ (1) NZ515339A (zh)
PT (1) PT1173177E (zh)
TR (1) TR200103119T2 (zh)
TW (1) TWI230066B (zh)
WO (1) WO2000066122A1 (zh)
ZA (1) ZA200108905B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60015516T2 (de) * 1999-04-30 2005-12-01 Sucampo Ag Verwendung von makroliden zur behandlung von trockenen augen
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
JP2005502621A (ja) 2001-07-06 2005-01-27 スキャンポ アーゲー インターロイキン２阻害剤および抗菌剤を含む局所投与用組成物
AR038628A1 (es) * 2002-03-04 2005-01-19 Novartis Ag Composicion oftalmica
CA2495103A1 (en) * 2002-08-09 2004-02-19 Sucampo Pharmaceuticals, Inc. Pharmaceutical compositions comprising fk506 derivatives and their use for the treatment of allergic diseases
US7354574B2 (en) 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
US20040198763A1 (en) * 2003-01-16 2004-10-07 Sucampo Ag Method of treating dry eye with a macrolide compound
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7083802B2 (en) * 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US7083803B2 (en) 2003-09-19 2006-08-01 Advanced Ocular Systems Limited Ocular solutions
US7087237B2 (en) 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
WO2005032534A1 (ja) 2003-10-06 2005-04-14 Ophtecs Corporation 涙液異常の治療のための眼科用組成物
EP3025713A1 (en) 2005-02-09 2016-06-01 Santen Pharmaceutical Co., Ltd Liquid formulations for treatment of diseases or conditions
WO2007011880A2 (en) 2005-07-18 2007-01-25 Minu, L.L.C. Enhanced ocular neuroprotection/neurostimulation
BRPI0707612B8 (pt) 2006-02-09 2021-05-25 Macusight Inc vaso lacrado e formulações líquidas contidas no mesmo
CA2645488C (en) 2006-03-23 2014-09-02 Macusight, Inc. Formulations comprising rapamycin and methods using same for vascular permeability-related diseases or conditions
EP2335735A1 (en) * 2009-12-14 2011-06-22 Novaliq GmbH Pharmaceutical composition for treatment of dry eye syndrome
KR20200069261A (ko) * 2017-05-30 2020-06-16 엑시모어 엘티디. 항생제 마크로라이드를 전달하는 안구건조증을 치료하기 위한 조성물 및 방법
WO2019060696A1 (en) 2017-09-25 2019-03-28 Surface Pharmaceuticals, Inc. OPTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR SURFACE DISEASE
US12070442B2 (en) 2018-12-27 2024-08-27 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA905202B (en) * 1989-07-05 1991-04-24 Fujisawa Pharmaceutical Co Aqueous liquid composition for external use
US5514686A (en) * 1991-04-26 1996-05-07 Fujisawa Pharmaceutical Co., Ltd. Use of macrolide compounds for eye diseases
ZA924953B (en) * 1991-07-25 1993-04-28 Univ Louisville Res Found Method of treating ocular inflammation
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
WO1999051215A2 (en) * 1998-04-06 1999-10-14 Fujisawa Pharmaceutical Co., Ltd. Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins
KR100406823B1 (ko) * 1998-04-27 2003-11-21 후지사와 야꾸힝 고교 가부시키가이샤 의약 조성물
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
DE60015516T2 (de) * 1999-04-30 2005-12-01 Sucampo Ag Verwendung von makroliden zur behandlung von trockenen augen

Also Published As

Publication number Publication date
EP1173177B1 (en) 2004-11-03
CA2372448A1 (en) 2000-11-09
AU4142900A (en) 2000-11-17
TWI230066B (en) 2005-04-01
AR023807A1 (es) 2002-09-04
NZ515339A (en) 2004-02-27
WO2000066122A1 (en) 2000-11-09
MXPA01010988A (es) 2004-04-21
IL146162A0 (en) 2002-07-25
AU777915B2 (en) 2004-11-04
HUP0200864A3 (en) 2004-07-28
CZ20013769A3 (cs) 2002-03-13
HUP0200864A2 (hu) 2002-07-29
BR0011225A (pt) 2002-03-19
CN1190194C (zh) 2005-02-23
HK1043321A1 (en) 2002-09-13
CN1353608A (zh) 2002-06-12
DE60015516D1 (de) 2004-12-09
ZA200108905B (en) 2002-12-24
PT1173177E (pt) 2005-03-31
EP1173177A1 (en) 2002-01-23
JP2012116857A (ja) 2012-06-21
JP2002543132A (ja) 2002-12-17
DE60015516T2 (de) 2005-12-01
TR200103119T2 (tr) 2002-04-22
EP1173177B2 (en) 2014-03-05
ES2232439T3 (es) 2005-06-01
NO20015288L (no) 2001-10-29
NO20015288D0 (no) 2001-10-29
JP5036934B2 (ja) 2012-09-26
ATE281167T1 (de) 2004-11-15
KR20020015316A (ko) 2002-02-27
HK1046099A1 (zh) 2002-12-27

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090426