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YU68902A - Mikrokapsule koje podrazumevaju funkcionalizovane polialkilcijanoakrilate - Google Patents

Mikrokapsule koje podrazumevaju funkcionalizovane polialkilcijanoakrilate

Info

Publication number
YU68902A
YU68902A YU68902A YUP68902A YU68902A YU 68902 A YU68902 A YU 68902A YU 68902 A YU68902 A YU 68902A YU P68902 A YUP68902 A YU P68902A YU 68902 A YU68902 A YU 68902A
Authority
YU
Yugoslavia
Prior art keywords
microcapsules
polyalkylcyanoacrylates
funcionalised
gas
filled microcapsules
Prior art date
Application number
YU68902A
Other languages
English (en)
Inventor
Georg Roessling
Andreas Briel
Nils Debus
Sabine Sydow
Birte Hofman
Peter Hauff
Michael Reinhardt
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of YU68902A publication Critical patent/YU68902A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polymerisation Methods In General (AREA)

Abstract

Ovaj pronalazak se odnosi na gasom ispunjene mikrokapsule koje se sastoje od funkcionalizovanih polialkilcijanoakrilata koji su dobijeni kopolimerizacijom jednog ili više alkilcijanoakrilata sa funkcionalnim monomerom i/ili delimičnom hidrolizom bočnog niza polialkilcijanoakrilata, kao i na proces za proizvodnju gasom ispunjenih mikrokapsula i njihova upotreba u ultrazvučnoj dijagnostici.[The invention relates to gas-filled microcapsules that consist of functionalized polyalkylcyanoacrylates that are produced by copolymerization of one or more alkylcyanoacrylates with a functional monomer and/or by partial side-chain hydrolysis of a polyalkylcyanoacrylate, as well as a process for the production of gas-filled microcapsules and their use for ultrasound diagnosis.
YU68902A 2000-03-15 2001-03-13 Mikrokapsule koje podrazumevaju funkcionalizovane polialkilcijanoakrilate YU68902A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10013850A DE10013850A1 (de) 2000-03-15 2000-03-15 Gasgefüllte Mikrokapseln enthaltend funktionalisiertes Polyalkylcyanacrylat, sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
YU68902A true YU68902A (sh) 2004-12-31

Family

ID=7635680

Family Applications (1)

Application Number Title Priority Date Filing Date
YU68902A YU68902A (sh) 2000-03-15 2001-03-13 Mikrokapsule koje podrazumevaju funkcionalizovane polialkilcijanoakrilate

Country Status (22)

Country Link
US (1) US20030157023A1 (sh)
EP (1) EP1267947A1 (sh)
JP (1) JP2004500397A (sh)
KR (1) KR20030041859A (sh)
CN (1) CN1424919A (sh)
AU (1) AU5218901A (sh)
BG (1) BG107085A (sh)
BR (1) BR0109169A (sh)
CA (1) CA2400906A1 (sh)
CZ (1) CZ20023101A3 (sh)
DE (1) DE10013850A1 (sh)
EA (1) EA200200881A1 (sh)
EE (1) EE200200524A (sh)
HU (1) HUP0300355A2 (sh)
IL (1) IL151472A0 (sh)
MX (1) MXPA02008874A (sh)
NO (1) NO20024382D0 (sh)
PL (1) PL364159A1 (sh)
SK (1) SK13202002A3 (sh)
WO (1) WO2001068150A1 (sh)
YU (1) YU68902A (sh)
ZA (1) ZA200208277B (sh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05007730A (es) 2003-02-04 2006-01-31 Bracco Int Bv Agentes de contraste para ultrasonido y proceso para la preparacion de los mismos.
JP5513708B2 (ja) 2003-12-22 2014-06-04 ブラッコ・シュイス・ソシエテ・アノニム 造影イメージング用の気体封入マイクロベシクル・アセンブリー
ATE466596T1 (de) 2004-01-20 2010-05-15 Sunnybrook & Womens College Hochfrequenz-ultraschall-darstellung mit kontrastmitteln
JP4837663B2 (ja) 2004-08-18 2011-12-14 ブラッコ・シュイス・ソシエテ・アノニム 造影画像化のためのガス充填微小胞組成物
US8275449B2 (en) 2005-11-11 2012-09-25 Visualsonics Inc. Overlay image contrast enhancement
EP2474327A1 (en) 2011-01-07 2012-07-11 RWTH Aachen Microdosing of ultrasound contrast agents
EP2545908A1 (en) 2011-07-11 2013-01-16 RWTH Aachen Medium for microbubbles or microparticles and preparation thereof
UA115789C2 (uk) * 2012-09-05 2017-12-26 Трейкон Фармасутікалз, Інк. Композиція антитіла до cd105 та її застосування
CA2903968A1 (en) 2013-03-15 2014-09-18 Westfaelische Wilhelms-Universitaet Muenster Detection of acute renal allograft rejection
CN104107440A (zh) * 2013-04-17 2014-10-22 刘哲 一种新型粒径可控的聚酯硬壳微泡体系的制备工艺
US10898581B2 (en) * 2014-01-16 2021-01-26 The Brigham And Women's Hospital, Inc. Targeted delivery of immunoregulatory drugs
WO2016049308A1 (en) * 2014-09-25 2016-03-31 Premier Dental Products Company Bondable microcapsules and surface functionalized fillers
WO2017207325A1 (de) 2016-06-02 2017-12-07 Evonik Degussa Gmbh Verfahren zur herstellung eines elektrodenmaterials
US20210129104A1 (en) * 2018-07-25 2021-05-06 Firmenich Sa Process for preparing microcapsules
CN110527007B (zh) * 2019-09-05 2022-11-08 大连合元医疗器械有限公司 聚（2-氰基丙烯酸）及其制备方法和应用
US20220332862A1 (en) * 2019-09-05 2022-10-20 Dalian Heyuan Medical Equipments Co., Ltd. Poly[alpha-cyanoacrylate] hydrolyzate and preparation method and application thereof
CN110498877B (zh) * 2019-09-05 2022-11-08 大连合元医疗器械有限公司 聚（2-羧基丙烯酸）及其制备方法和应用
DE102021105820A1 (de) 2021-03-10 2022-09-15 Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen Theranostische polymere Mikropartikel für die Behandlung von vaskulären Erkrankungen durch ultraschallvermittelte Wirkstoffabgabe
WO2023156806A1 (en) * 2022-02-21 2023-08-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for manufacturing bubbles having a polymeric shell using sound waves for generating the bubbles
CN116731301B (zh) * 2023-06-30 2024-03-19 珠海市凯拓塑料制品有限公司 一种生物基防刮花吸塑托盘及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4219724A1 (de) * 1992-06-13 1993-12-16 Schering Ag Verwendung von Mikrokapseln als Kontrastmittel für die Farbdoppler-Sonographie
US5425366A (en) * 1988-02-05 1995-06-20 Schering Aktiengesellschaft Ultrasonic contrast agents for color Doppler imaging
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106673D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
DE4219723A1 (de) * 1992-06-13 1993-12-16 Schering Ag Mikropartikel, Verfahren zu deren Herstellung, sowie die Verwendung dieser in der Diagnostik
US6383470B1 (en) * 1992-09-26 2002-05-07 Thomas Fritzsch Microparticle preparations made of biodegradable copolymers
DE4232755A1 (de) * 1992-09-26 1994-03-31 Schering Ag Mikropartikelpräparationen aus biologisch abbaubaren Mischpolymeren

Also Published As

Publication number Publication date
IL151472A0 (en) 2003-04-10
HUP0300355A2 (hu) 2003-06-28
BR0109169A (pt) 2002-12-10
EE200200524A (et) 2004-04-15
CA2400906A1 (en) 2001-09-20
EA200200881A1 (ru) 2003-06-26
CN1424919A (zh) 2003-06-18
NO20024382L (no) 2002-09-13
DE10013850A1 (de) 2001-09-20
KR20030041859A (ko) 2003-05-27
CZ20023101A3 (cs) 2003-01-15
SK13202002A3 (sk) 2003-02-04
MXPA02008874A (es) 2003-02-10
BG107085A (bg) 2004-04-30
AU5218901A (en) 2001-09-24
JP2004500397A (ja) 2004-01-08
EP1267947A1 (en) 2003-01-02
ZA200208277B (en) 2004-01-30
NO20024382D0 (no) 2002-09-13
WO2001068150A1 (en) 2001-09-20
US20030157023A1 (en) 2003-08-21
PL364159A1 (en) 2004-12-13

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