WO2020170646A1

WO2020170646A1 - Method for producing emulsion composition

Info

Publication number: WO2020170646A1
Application number: PCT/JP2020/000685
Authority: WO
Inventors: 忠夫辻; 恵広柳澤
Original assignee: 株式会社カネカ
Priority date: 2019-02-19
Filing date: 2020-01-10
Publication date: 2020-08-27

Abstract

The purpose of the present invention is to provide a method capable of easily producing an emulsion composition having an unprecedented feeling of use. This method for producing an emulsion composition is characterized in that the emulsion composition contains two or more oily components, and is also characterized by including: a step for dissolving a surfactant in a polyhydric alcohol or a mixed solvent of water and a polyhydric alcohol to obtain a surfactant solution; a step for mixing each of two or more oily components with the surfactant solution to obtain two or more gel-like compositions; and a step for dispersing the two or more gel-like compositions in an aqueous solvent.

Description

Method for producing emulsified composition

The present invention relates to a method capable of easily producing an emulsified composition having an unprecedented unique feeling of use.

❖ Emulsified compositions in which an aqueous component and an oil component, which are essentially immiscible, are stably mixed with a surfactant are used in various fields. Various mixing methods have been developed so far, and examples thereof include a D-phase emulsification method and a liquid crystal emulsification method that do not require strong dispersion such as strong stirring and shearing.

In the D-phase emulsification method, an oily component is dispersed in a solution obtained by dissolving a surfactant in water and a polyhydric alcohol to obtain an O/D gel emulsion, and then water is added to the O/D gel emulsion. To obtain an O/W emulsion (Patent Document 1, Non-Patent Document 1). The liquid crystal emulsification method includes, for example, forming a gel-like O/LC emulsion in which an oil phase is dispersed and retained in a lamellar liquid crystal of a surfactant, and then adding water to the O/LC emulsion to form an O/W emulsion. It is a method of obtaining (Patent Document 2).

However, in order to obtain an emulsion by these methods, the mixing ratio and mixing conditions of each component are extremely limited. For example, it is necessary to make the amount of the oily component relatively small and the amount of the surfactant relatively large, so that it can be said that the feeling of use is poor. Therefore, the mechanical stirring method is still generally used for the production of the emulsion composition.

JP-A-63-072335 JP-A-9-124432

As described above, the mechanical stirring method is generally used in the production of the emulsion composition. However, the mechanical stirring method often requires complicated steps such as heating, vacuuming, stirring, and cooling, and since strong stirring requires high energy consumption such as electric power, a step of obtaining an emulsified composition. Has the drawback that it cannot be interrupted. Further, the emulsified composition is also used as a composition that comes into contact with the skin such as cosmetics, and there is a demand for an emulsified composition having a more excellent feeling of use, but the characteristics of the emulsified composition obtained by a mechanical stirring method. Since it depends only on the component composition, it can be said that it is difficult to develop an emulsion composition having a new feeling of use by a mechanical stirring method.
Therefore, an object of the present invention is to provide a method for easily producing an emulsified composition having an unprecedented feeling of use.

The present inventors have conducted extensive studies to solve the above problems. As a result, when different gel compositions are prepared from two or more oily components and the two or more gel compositions are dispersed in an aqueous solvent, surprisingly, droplets of the gel composition are generated. The present invention has been completed by finding that it is possible to easily produce an emulsified composition exhibiting an unprecedented usability by not independently integrating with each other but independently stabilizing.
The present invention will be described below.

[1] A method for producing an emulsified composition, comprising:
The emulsified composition contains two or more oily components,
A step of dissolving a surfactant in a polyhydric alcohol or a mixed solvent of water and a polyhydric alcohol to obtain a surfactant solution,
Obtaining two or more gel-like compositions by mixing the two or more oily components with the surfactant solution, respectively, and
A method comprising the step of dispersing the two or more gel compositions in an aqueous solvent.

[2] The method according to [1] above, wherein the ratio of the surfactant to the gel composition is 0.01% by mass or more and 10% by mass or less.

[3] The method according to [1] or [2] above, wherein the ratio of the surfactant to the emulsified composition is 0.01% by mass or more and 5% by mass or less.

[4] The method according to [1] or [2] above, wherein the ratio of the surfactant to the emulsified composition is 0.01% by mass or more and less than 2% by mass.

[5] The method according to any one of [1] to [4] above, wherein the surfactant is a biosurfactant.

[6] The method according to any one of [1] to [5] above, wherein the biosurfactant is one or more cyclic lipopeptide biosurfactants selected from surfactin, arthrofactin, iturin, and salts thereof. ..

[7] The polyhydric alcohol is one or more selected from glycerin, diglycerin, polyethylene glycol, 1,3-butylene glycol, sorbitol, and xylitol, according to any one of [1] to [6] above. Method.

[8] The method according to any one of [1] to [6] above, wherein the polyhydric alcohol contains glycerin.

[9] The above-mentioned [1] to [wherein the oily component is one or more selected from hydrocarbons, waxes, fats and oils, esters, fatty acids, silicone oils, higher alcohols and alkyl glyceryl ethers. The method according to any one of 8].

According to the method of the present invention, it is possible to easily produce an emulsified composition in which two or more kinds of droplets each containing different oily components are dispersed. Further, the emulsified composition according to the present invention in which two or more kinds of droplets respectively containing different oily components are dispersed, even if it contains two or more kinds of oily components, they are included in one droplet. Compared with the conventional emulsified composition which has been worn out, it shows a much better feeling in use. Therefore, the method of the present invention has an extremely excellent feeling in use and is industrially very excellent as a technique for easily producing an emulsified composition that can be used, for example, in cosmetics and external preparations for skin.

Hereinafter, the method for producing the emulsion composition according to the present invention will be described with reference to specific examples, but the present invention is not limited to the following modes.

1. Step of Preparing Surfactant Solution In this step, the surfactant is dissolved in a polyhydric alcohol or a mixed solvent of water and a polyhydric alcohol to obtain a surfactant solution.

As the surfactant, anionic surfactant, cationic surfactant, nonionic surfactant, amphoteric surfactant can be used without particular limitation.

The anionic surfactant is a surfactant having a hydrophilic portion containing an anionic group such as a carboxy group or a sulfonic acid group and a non-hydrophilic portion such as a long chain alkyl group. For example, alkyl sulfate ester salts such as sodium lauryl sulfate, potassium lauryl sulfate, ammonium lauryl sulfate, magnesium lauryl sulfate, monoethanolamine lauryl sulfate, sodium myristyl sulfate, sodium stearyl sulfate, sodium oleyl sulfate; POE(2) sodium lauryl ether sulfate, POE (3) alkyl ether sulfate ester salt such as sodium myristyl ether sulfate; N-acylmethyl taurine salt such as potassium coconut oil fatty acid methyl taurine and sodium lauroyl methyl taurine; N-acyl glutamate salt such as coconut oil fatty acid acyl glutamic acid; lauroyl N-acyl methylalanine salts such as sodium methylalanine; N-acyl sarcosine salts such as sodium lauroyl sarcosine; Acyl lactate salts such as sodium stearoyl lactylate; Fatty acid salts such as potassium coconut oil fatty acid, potassium laurate, triethanolamine laurate And so on. “POE” is an abbreviation for polyoxyethylene, and the number in parentheses indicates the number of moles added.

Cation surfactant is a surfactant having a hydrophilic portion containing a cationic group such as an ammonium group and a non-hydrophilic portion such as a long-chain alkyl group. Examples thereof include alkyl quaternary ammonium salts such as lauryltrimethylammonium chloride, stearyltrimethylammonium bromide and dicocoyldimethylammonium chloride; amine salts such as dimethylstearylamine and stearic acid diethylaminoethylamide.

A nonionic surfactant is a surfactant that does not have a cationic group and an anionic group, but has a hydrophilic portion and a non-hydrophilic portion. Examples thereof include polyoxyethylene alkyl ethers such as POE lauryl ether and POE cetyl ether; glycerin fatty acid esters such as glyceryl monostearate; and sorbitan fatty acid esters such as sorbitan monolaurate.

An amphoteric surfactant is a surfactant having both a cationic group and an anionic group and having a hydrophilic portion and a non-hydrophilic portion. Examples thereof include amino acid-type amphoteric surfactants such as sodium lauryldiaminoethylglycine and sodium laurylaminopropionate; betaine-type amphoteric surfactants such as coconut oil alkyl betaine, lauryl dimethylamino acetic acid betaine, and lauryl hydroxysulfobetaine.

Alternatively, a biosurfactant may be used as the surfactant. A biosurfactant is a natural surfactant produced by a microorganism, and generally has high biodegradability and low skin irritation to the human body, and therefore has extremely high safety to the environment and human body. Further, the emulsion composition of the present invention tends to be produced with a smaller amount of biosurfactant than other surfactants. The biosurfactants used in the present invention include lipopeptide compounds surfactin, arthrofactin and iturin; glycolipids mannosylerythritol lipid, sophorolipid, trehalose lipid, rhamnolipid; fatty acid spiculisporic acid; polymer emalzan; But not limited thereto.

Among the above, since the effect of stabilizing the emulsion composition in a small amount can be obtained, lipopeptide biosurfactant is preferable, surfactin which is a cyclic lipopeptide biosurfactant, arthrofactin, iturin, or a salt thereof is more preferable, Surfactin or a salt thereof is particularly preferable.

Here, the surfactin salt is a compound represented by the general formula (I), or a composition containing two or more kinds of the compounds.

[In the formula, X represents an amino acid residue selected from leucine, isoleucine, and valine, R ¹ represents a C _9-18 alkyl group, and M ⁺ represents an alkali metal ion or a quaternary ammonium ion.]

The amino acid residue as X may be L-form or D-form, but L-form is preferable.

The “C _9-18 alkyl group” refers to a linear or branched monovalent saturated hydrocarbon group having 9 or more and 18 or less carbon atoms. For example, n-nonyl, 6-methyloctyl, 7-methyloctyl, n-decyl, 8-methylnonyl, n-undecyl, 9-methyldecyl, n-dodecyl, 10-methylundecyl, n-tridecyl, 11-methyldodecyl , N-tetradecyl, n-pentadecyl, n-hexadecyl, n-heptadecyl, n-octadecyl and the like.

The alkali metal ion is not particularly limited, but examples thereof include lithium ion, sodium ion and potassium ion, with sodium ion being preferred.

Examples of the substituent of the quaternary ammonium ion include alkyl groups such as methyl, ethyl, n-propyl, isopropyl, n-butyl and tert-butyl; aralkyl groups such as benzyl, methylbenzyl and phenylethyl; phenyl and toluyl. , Organic groups such as aryl groups such as xylyl and the like. Examples of the quaternary ammonium ion include tetramethylammonium ion, tetraethylammonium ion, pyridinium ion and the like.

Arthrofactin is represented by general formula (II).

Arslofactin may have one D-aspartic acid and one L-aspartic acid in the structure, and may form an alkali metal ion or a quaternary ammonium ion.

Iturin is represented by the general formula (III).

In formula (III), R ² represents a C _9-18 alkyl group, and for example, —(CH ₂ ) ₁₀ CH ₃ , —(CH ₂ ) ₈ CH(CH ₃ )CH ₂ CH ₃ , —(CH ₂ ) ₉ Indicates CH(CH ₃ ) ₂ .

In the present invention, it is preferable to use an anionic surfactant or a cationic surfactant, and it is more preferable to use an anionic surfactant. In the emulsified composition according to the present invention, it is considered that the droplets are more stably present due to the electrostatic repulsive force of these surfactants. Most biosurfactants are anionic surfactants having an anionic group such as a carboxy group or a phenolic hydroxyl group.

In this step, the surfactant is dissolved using polyhydric alcohol or a mixed solvent of water and polyhydric alcohol as the solvent. The “polyhydric alcohol” is an organic compound having two or more hydroxyl groups in the molecule. For example, ethylene glycol, 1,2-propanediol, 1,3-propanediol, 1,4-butanediol, 1,5-pentanediol, 1,6-hexanediol, 1,7-heptanediol, 1,8 -Aliphatic diols such as octanediol, neopentyl glycol and 1,4-butenediol; trivalent or higher polyhydric alcohols such as glycerin, diglycerin, triglycerin, pentaerythritol, trimethylolpropane, sorbitol and xylitol. To be The polyhydric alcohol is preferably one or more selected from glycerin, diglycerin, polyethylene glycol, 1,3-butylene glycol, sorbitol, and xylitol. As the polyhydric alcohol, glycerin or a mixture of polyhydric alcohol other than glycerin and glycerin is preferable. Examples of such a mixture include a mixture of glycerin and a polyhydric alcohol selected from diglycerin, sorbitol, and xylitol. When glycerin and other polyhydric alcohol are mixed and used, the ratio thereof may be appropriately adjusted, and depends on whether the polyhydric alcohol other than glycerin is solid or liquid at room temperature, for example, glycerin And the ratio of the other polyhydric alcohol to the total of the other polyhydric alcohol can be 1% by mass or more and 95% by mass or less.

Especially when using a polyhydric alcohol that is solid at room temperature and atmospheric pressure, it is preferable to use a mixed solvent of water and a polyhydric alcohol. However, when using a polyhydric alcohol that is liquid at normal temperature and pressure, a mixed solvent of water and a polyhydric alcohol may be used. The concentration of the polyhydric alcohol in the mixed solvent is not particularly limited and may be appropriately adjusted. For example, it can be 5% by mass or more and 95% by mass or less.

Surfactant solution, that is, the ratio of the surfactant to the total of the surfactant and the polyhydric alcohol or the mixed solvent of water and the polyhydric alcohol may be appropriately adjusted, for example, 0.01 mass% or more, It can be 50 mass% or less. The ratio is preferably 0.1% by mass or more, more preferably 0.2% by mass or more, 15% by mass or less, and more preferably 10% by mass or less.

To prepare the surfactant solution, the surfactant may be added to the polyhydric alcohol or a mixed solvent of water and the polyhydric alcohol, and then the mixture may be stirred until the surfactant is dissolved. When the surfactant is difficult to dissolve, the mixture may be heated to 40°C or higher and 90°C or lower.

2. Step of Preparing Gel-like Composition In this step, two or more kinds of oily components are respectively mixed with the surfactant solution obtained in the above-mentioned Step 1 to obtain two or more kinds of gel-like composition. The gel composition refers to a composition having a viscosity of 3000 mPa·s or more, and the viscosity is measured according to JIS Z 8803:2011.

The oily component used in the method of the present invention is not particularly limited as long as it is not mixed with water at an arbitrary ratio. More specifically, it means 1 g or 1 mL of a substance that does not dissolve within 30 minutes when it is put in 1000 mL or more of water and shaken vigorously for 5 seconds at 20±5° C. every 30 minutes. Examples of the oily component include hydrocarbons such as squalane, liquid paraffin, light liquid isoparaffin, ceresin, polyethylene powder, squalene, microcrystalline wax, vaseline, liquid isoparaffin, polybutene, and mineral oil; beeswax, carnauba wax, candelilla wax, Waxes such as jojoba oil, lanolin, whale wax; macadamia nut oil, olive oil, cottonseed oil, soybean oil, avocado oil, rice bran oil, rice oil, rice germ oil, palm kernel oil, castor oil, rosehip oil, evening primrose oil, camellia. Oils, horse oil, grape seed oil, coconut oil, meadow home oil, shea butter, corn oil, safflower oil, sesame oil and other oils and fats; ethylhexyl palmitate, isononyl isononanoate, isopropyl myristate, ethyl oleate, tri( Caprylic acid/capric acid) Glyceryl, 2-ethylhexanoic acid cetyl, tri-2-ethylhexanoic acid glyceryl, diisopropyl sebacate, cholesteryl hydroxystearate, and other esters; fatty acids such as myristic acid, stearic acid, and oleic acid; methyl Examples thereof include silicone oils such as polysiloxane, methylphenylpolysiloxane, and amino-modified silicone; higher alcohols such as cetanol and oleyl alcohol; and alkyl glyceryl ethers such as batyl alcohol and chimyl alcohol.

In the present invention, two or more oily ingredients are used. The two or more oily components are not particularly limited as long as they are different from each other. For example, in the present invention, a gel composition is prepared for each oily component and, in order to disperse it in an aqueous solvent, a combination of a silicone oil and another oily component, a combination of a hydrocarbon and a vegetable oil, and the like, in the conventional method. It is possible to use a combination of oily components which has been difficult to use together.

The upper limit of the number of oily components to be used is not particularly limited, but can be, for example, 40 or less, preferably 20 or less, more preferably 10 or less, still more preferably 5 or less.

In the method of the present invention, a gel composition is prepared for each oil component. Therefore, the surfactant solution obtained in the above step 1 is divided according to the number of oily components to be used, and the oily components are added to and mixed with each surfactant solution to form two or more gel compositions. To get

The ratio of the surfactant in each gel composition may be appropriately adjusted, but can be, for example, 0.01% by mass or more and 20% by mass or less. The ratio is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, and preferably 10% by mass or less, more preferably 5% by mass or less.

The ratio of the oily component in each gel composition may be appropriately adjusted, but can be, for example, 20% by mass or more and 95% by mass or less. The ratio is preferably 25% by mass or more, more preferably 30% by mass or more.

The conditions for preparing the gel composition are not particularly limited, but, for example, the oily component may be intermittently or continuously added to the stirred surfactant solution little by little. Even after adding the whole amount of the oily component, it is preferable to sufficiently stir or knead so that the gel composition becomes uniform.

3. Step of producing emulsified composition In this step, the emulsified composition is obtained by dispersing two or more gel-like compositions obtained in the above Step 2 in an aqueous solvent. Conventionally, there was an example in which an emulsion composition containing two or more oily components was prepared by mixing two or more emulsion compositions and mixing them. However, preparation of an emulsion composition generally requires strong stirring, and large-scale synthesis requires large-scale equipment. On the other hand, in the method of the present invention, a gel composition is first prepared, and relatively weak stirring power is sufficient for the preparation of the gel composition, and also when the gel composition is dispersed in an aqueous solvent. Relatively weak stirring power is sufficient.

Examples of the water-based solvent in which the gel composition is dispersed in the present invention include water and a mixed solvent of water and a water-miscible organic solvent. The water-miscible organic solvent means an organic solvent that can be mixed with water without limitation, and examples thereof include C _1-4 alcohols such as ethanol and isopropanol. The ratio of the water-miscible organic solvent in the mixed solvent of water and the water-miscible organic solvent may be appropriately adjusted, but can be, for example, 0.01% by mass or more and 50% by mass or less, and 0.1% by mass. % Or more, 40% by mass or less is preferable, and 30% by mass or less is more preferable.

The amount of the aqueous solvent used may be appropriately adjusted, but for example, it is preferable that the ratio of the surfactant to the emulsified composition is 0.01% by mass or more and 20% by mass or less. The ratio is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, even more preferably 0.5% by mass or more, and preferably 10% by mass or less, more preferably 5% by mass or less. It is even more preferably 3% by mass or less.

Although strong stirring force and strong shearing force are required to manufacture an emulsion composition by the mechanical stirring method, in this step, the emulsion composition can be obtained with relatively weak stirring force and shearing force. For example, an emulsified composition can be obtained with a weak stirring force of 500 rpm or less using a disper mixer, paddle mixer, or the like, but the stirring conditions are not particularly limited as long as it can be uniformly dispersed.

When other components are added to the emulsion composition of the present invention, the above step 1 (surfactant solution preparation step), the above step 2 (gel composition preparation step) and this step (emulsion composition) It may be added in any one or more of the manufacturing steps (1). In addition to the above-mentioned surfactants, polyhydric alcohols, oily components, and aqueous solvents which are essential components, as an optional component that may be added to the emulsified composition according to the present invention, for example, C ₁ such as ethanol or isopropyl alcohol may be used. _-4 Alcohols: thickeners, ultraviolet absorbers, antioxidants, emollients, solubilizers, anti-inflammatory agents, moisturizers, preservatives, bactericides, pigments, fragrances, powders and the like.

The emulsified composition according to the present invention contains two or more oily components, each of which is contained in another droplet, and each droplet is stably independent. Even if it contains, it exhibits an excellent feeling of use, which is different from the conventional emulsified composition in which the two or more oily components are present in one droplet. Therefore, the emulsion composition according to the present invention is particularly useful as a cosmetic or a skin external preparation that is directly applied to the skin.

This application claims the benefit of priority based on Japanese Patent Application No. 2019-27779 filed on February 19, 2019. The entire contents of the specification of Japanese Patent Application No. 2019-27779 filed on Feb. 19, 2019 are incorporated herein by reference.

Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to the following examples, and appropriate changes may be made within a range that can conform to the gist of the preceding and the following. Of course, it is possible to carry out, and all of them are included in the technical scope of the present invention.

Example 1: Production of emulsified composition (1) Preparation of gel composition A Surfactin sodium was added to glycerin at a mass ratio shown in Table 1 and dissolved by stirring at room temperature. Squalane was added to the obtained solution, and the mixture was slowly stirred manually at room temperature with a stir bar to completely disperse the gel composition A.

(2) Preparation of Gel Composition B Surfactin sodium was added to glycerin at the mass ratio shown in Table 1 and dissolved by stirring at room temperature. Dimethylpolysiloxane oil (manufactured by Shin-Etsu Chemical Co., Ltd., kinematic viscosity: 20 cs) was added to the obtained solution, and the mixture was slowly stirred manually at room temperature by using a stir bar to completely disperse the gel composition B. Obtained.

(3) Production of emulsified composition Gel-like composition A and gel-like composition B were added to purified water at the mass ratios shown in Table 2, and the mixture was stirred slowly at room temperature manually with a stir bar to obtain a uniform mixture. An emulsified composition was obtained by dispersing.

Comparative Example 1 Production of Emulsified Composition By adding only the gel composition A to purified water at the mass ratio shown in Table 2, slowly stirring manually with a stir bar at room temperature, and completely homogenously dispersing the composition. An emulsified composition was obtained.

Comparative Example 2: Manufacture of Emulsion Composition By adding only the gel composition B to purified water at the mass ratio shown in Table 2 and slowly stirring manually with a stir bar at room temperature, a uniform dispersion is obtained. An emulsified composition was obtained.

Comparative Example 3: Production of Emulsion Composition (1) Preparation of Gel Composition C Surfactin sodium was added to glycerin at a mass ratio shown in Table 1 and dissolved by stirring at room temperature. Squalane and dimethylpolysiloxane oil (manufactured by Shin-Etsu Chemical Co., Ltd., kinematic viscosity: 20 cs) were added to the obtained solution, and the mixture was slowly stirred manually at room temperature with a stir bar to completely disperse the gel composition. I got C.

(2) Production of Emulsion Composition The gel composition C was added to purified water at the mass ratio shown in Table 2 and stirred at room temperature to obtain an emulsion composition.

Test example 1
Six test subjects applied about 1 g of the emulsified composition of Example 1 or Comparative Examples 1 to 3 to the inside of the upper arm, the inside of the wrist, or the back of the hand, and the items regarding the feeling of use were evaluated on a five-point scale. .. The results are shown in Table 3. It should be noted that the "complexity of touch" does not mean a feeling of being simply oiled, but a complex feeling with depth and depth, but a good feeling. In addition, the “comprehensive evaluation” is the overall satisfaction when used as a cosmetic product in consideration of each item.

According to a concrete opinion of the test subject, the composition of Comparative Example 1 has a strong oily feel, but the oily feel is too strong and does not fit to the skin.
On the other hand, the composition of Comparative Example 2 had a refreshing feel due to the silicone oil. It was said that the composition of Comparative Example 3 had an intermediate feeling of use between the composition of Comparative Example 1 and the composition of Comparative Example 2.
On the other hand, the composition of Example 1 has both the oily feeling of squalane and the refreshing feeling of silicone oil as well as the composition of Comparative Example 3, but the excellent characteristics of each oily component are maximized. The overall evaluation was high, with a deep and unique feeling of use.

Examples 2 to 6 and Comparative Examples 4 and 5: Production of Emulsion Composition (1) Preparation of Gel Composition D Surfactin sodium was added to glycerin at a mass ratio shown in Table 4 and dissolved by stirring at room temperature. did. Squalane was added to the obtained solution, and the mixture was slowly stirred manually at room temperature by using a stir bar and completely dispersed uniformly to obtain a gel composition D.

(2) Preparation of Gel Composition E Surfactin sodium was added to glycerin at the mass ratio shown in Table 4 and dissolved by stirring at room temperature. Glyceryl tri(caprylic acid/capric acid) was added to the obtained solution, and the mixture was slowly stirred manually at room temperature by using a stir bar to completely and uniformly disperse the gel composition E.

(3) Production of emulsified composition Gel-like composition D and gel-like composition E were added to purified water in the mass proportions shown in Table 5, and the mixture was stirred slowly at room temperature manually with a stir bar to obtain a uniform mixture. An emulsified composition was obtained by dispersing.

Test example 2
Six subjects were asked to apply about 1 g of the emulsified composition of Examples 2 to 6 or Comparative Examples 4 and 5 to the inside of the upper arm, the inside of the wrist, or the back of the hand, and the items related to the feeling of use were evaluated on a five-point scale. received. The results are shown in Table 6.

As shown in the results shown in Table 6, the emulsion composition comprising the gel composition D had a refreshing feeling, and the emulsion composition comprising the gel composition E had a strong moist feeling.
In Examples 2 to 6, the mixing ratios of the gel composition D and the gel composition E were changed stepwise, and from Example 2 to Example 6, the ratio of the emulsified composition D having a refreshing feeling was reduced to give a moist feeling. The ratio of the strong emulsified composition E was increased, and accordingly, the feeling of use gradually changed from a feeling of freshness to a feeling of moistness.

Example 7, Comparative Examples 6 to 8: Production of Emulsified Composition (1) Preparation of Gel Composition F Surfactin sodium was added to a mixed solvent of diglycerin and purified water at a mass ratio shown in Table 7, It was dissolved by stirring at room temperature. Diisostearyl malate was added to the obtained solution, and the mixture was slowly stirred manually at room temperature with a stir bar to completely and uniformly disperse the gel composition F.

(2) Preparation of gel composition G At a mass ratio shown in Table 7, surfactin sodium was added to a mixed solvent of diglycerin and purified water, and dissolved by stirring at room temperature. Ethylhexyl palmitate was added to the obtained solution, and the mixture was slowly stirred manually at room temperature with a stirrer to completely uniformly disperse the gel composition G.

(3) Preparation of Gel Composition H Surfactin sodium was added to the mixed solvent of diglycerin and purified water at the mass ratio shown in Table 7 and dissolved by stirring at room temperature. To the obtained solution, diisostearyl malate and ethylhexyl palmitate were added, and the mixture was slowly stirred manually at room temperature with a stir bar to obtain a gel composition H by completely and uniformly dispersing it.

(4) Production of Emulsion Composition Gel composition F and gel composition G, or gel composition F, gel composition G or gel composition H in purified water at the mass proportions shown in Table 8. The resulting emulsion composition was slowly stirred manually at room temperature with a stir bar and completely dispersed to obtain an emulsified composition.

Test example 3
Six test subjects applied about 1 g of the emulsified composition of Example 7 or Comparative Examples 6 to 8 to the inside of the upper arm, the inside of the wrist, or the back of the hand, and the items regarding the feeling of use were evaluated on a five-point scale. .. The results are shown in Table 9.

As shown in the results shown in Table 9, Comparative Example 6 was an emulsified composition prepared only from the gel composition F containing one oily component, and had a strong moist feeling but a very strong stickiness. Comparative Example 7 was an emulsified composition prepared from only the gel composition G containing one oily component, and had a strong refreshing feeling, weak moistening feeling, and was not sticky. Comparative Example 8 is an emulsified composition prepared only from the gel composition H containing two oily components, and the purpose was to reduce stickiness, but the premixed oil component could not suppress stickiness.
On the other hand, Example 7 is an emulsified composition prepared by mixing the gel composition F and the gel composition G each containing one oily component, and the emulsified compositions having different feelings of use are coexistent. It had a moist feeling and a refreshing feeling, and was able to achieve both non-stickiness.

Claims

A method for producing an emulsified composition, comprising:
The emulsified composition contains two or more oily components,
A step of dissolving a surfactant in a polyhydric alcohol or a mixed solvent of water and a polyhydric alcohol to obtain a surfactant solution,
Obtaining two or more gel-like compositions by mixing the two or more oily components with the surfactant solution, respectively, and
A method comprising the step of dispersing the two or more gel compositions in an aqueous solvent.
The method according to claim 1, wherein the ratio of the surfactant to the gel composition is 0.01% by mass or more and 10% by mass or less.
The method according to claim 1 or 2, wherein the ratio of the surfactant to the emulsified composition is 0.01% by mass or more and 5% by mass or less.
The method according to claim 1 or 2, wherein the ratio of the surfactant to the emulsified composition is 0.01% by mass or more and less than 2% by mass.
The method according to any one of claims 1 to 4, wherein the surfactant is a biosurfactant.
The method according to any one of claims 1 to 5, wherein the biosurfactant is one or more cyclic lipopeptide biosurfactants selected from surfactin, arthrofactin, iturin, and salts thereof.
The method according to any one of claims 1 to 6, wherein the polyhydric alcohol is one or more selected from glycerin, diglycerin, polyethylene glycol, 1,3-butylene glycol, sorbitol, and xylitol.
The method according to any one of claims 1 to 6, wherein the polyhydric alcohol contains glycerin.
9. The oily component is one or more selected from hydrocarbons, waxes, oils and fats, esters, fatty acids, silicone oils, higher alcohols and alkyl glyceryl ethers. The described method.