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WO2000059519A2 - Substance active et combinaison de substances actives pour l'homme et les animaux - Google Patents

Substance active et combinaison de substances actives pour l'homme et les animaux Download PDF

Info

Publication number
WO2000059519A2
WO2000059519A2 PCT/DE2000/000929 DE0000929W WO0059519A2 WO 2000059519 A2 WO2000059519 A2 WO 2000059519A2 DE 0000929 W DE0000929 W DE 0000929W WO 0059519 A2 WO0059519 A2 WO 0059519A2
Authority
WO
WIPO (PCT)
Prior art keywords
active ingredient
ingredient combination
extracts
combination according
colostral milk
Prior art date
Application number
PCT/DE2000/000929
Other languages
German (de)
English (en)
Other versions
WO2000059519A3 (fr
Inventor
Carl-Heinz Kapitz
Gerhard Knapp
Original Assignee
Kapitz Carl Heinz
Gerhard Knapp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999114646 external-priority patent/DE19914646A1/de
Priority claimed from DE1999163628 external-priority patent/DE19963628A1/de
Priority claimed from DE2000100157 external-priority patent/DE10000157A1/de
Application filed by Kapitz Carl Heinz, Gerhard Knapp filed Critical Kapitz Carl Heinz
Priority to EP00929249A priority Critical patent/EP1180940A2/fr
Priority to AU47426/00A priority patent/AU4742600A/en
Publication of WO2000059519A2 publication Critical patent/WO2000059519A2/fr
Publication of WO2000059519A3 publication Critical patent/WO2000059519A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206—Colostrum; Human milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/986—Milk; Derivatives thereof, e.g. butter

Definitions

  • the invention relates to an active ingredient and in particular an active ingredient combination for humans and animals, based on colostral milk products and / or colostral milk extracts.
  • Colostral milk or colostrum also known as first or first milk
  • first milk is a secretion of the female mammary glands, usually yellowish due to carotenes, which is often formed during pregnancy, but especially in the first days after birth.
  • Colostrum differs from mature breast milk primarily in its higher protein and vitamin content, especially vitamins A and C, with approximately the same carbohydrate and slightly reduced fat content.
  • Colostrum also has leukocytes loaded with fat drops, the colostrum bodies or colostral bodies.
  • the colostrum which is rich in immunoglobulins, is the first food of the newborn that is important for the first days of life after birth.
  • Health and well-being in humans and animals depend in particular on the food or nutrients ingested and also on how the body processes these substances. These substances can be divided into three different groups of active ingredients. The first shows the substances and active ingredients that are contained in animal products. The second is Mineral group or that of the metal salts with their respective active ingredient content. The third can be assigned to the general plant area. A large number of active ingredients that are contained in the plants are known here.
  • Colostrum of bovine origin has only been available on the market for a few years. It has been possible to gently filter out the valuable ingredients from the colostral milk.
  • the dairy cows produce more colostral milk than the calf needs. Part of the colostral milk is fed to the calves and the other part is brought to the market in a filtered state.
  • Colostral milk extracts are commercially available in the form of granules or as drinkable extracts.
  • Dead Sea Salt extracted from the Dead Sea cleaned and can also be used as a salt bath at home, for example.
  • Dead Sea salt minerals are also used as raw materials for external use in Kos etika.
  • Plant components and / or plant extracts have been known for thousands of years and are used in all areas of health.
  • Active ingredient groups in the individual application are very diverse and still unexplored in many areas, the effectiveness of the three active ingredient groups mentioned above could be demonstrated for internal and external use, especially for the entire skin area.
  • Active ingredient groups contain active ingredients that can have a positive effect on cell metabolism in particular. This has effects in the case of defects in the immune system as well as allergic reactions, skin diseases of various types, neurodermatitis or psoriasis. Furthermore, there are cell regeneration active substances and medicinal substances for the treatment of wounds, sunburn, acne, in the tooth area, skin injuries, all kinds of skin infections, pimples, herpes etc.
  • an active ingredient is now made available which is based on colostral milk products and / or
  • Colostral milk extracts of humans based on sheep and / or goat. Used alone or in the combination of active ingredients explained below, for example as a dietary supplement, food, cosmetic, pharmaceutical and / or as a medicament and as an additive used in cosmetics, beverages, pharmaceuticals, food, nutritional supplements and in the pharmaceutical field, the active ingredient can be used externally and / or are used internally in humans and animals. It has these colostral milk products and / or
  • Human, sheep and / or goat colostrum extracts are significantly different from those of bovine origin and can be used effectively.
  • colostral milk products and / or colostral milk extracts from humans sheep and / or goats in an amount of 0.1 to 60 parts of a hundred, for example
  • Carrier mass ad 100 parts goat colostrum 0.1-60 parts plant extracts 0.1-17 parts testes extracts 0.1-2 parts
  • colostral milk products and / or colostral milk extracts from humans sheep and / or goats are used as food and nutritional supplements according to the invention. These include in particular refreshment and energy drinks and bars with fiber-containing nutrients and fiber.
  • a tablet, powder or capsule form is preferred as a food supplement.
  • Recipe of a capsule as a recipe for a dietary supplement Fruit juice:
  • Vitamin E 2% Vitamin E 5% ß-carotenes 15% colostrum (goat) 35%
  • Formulation of a formulation of an aqueous solution Cream formulation:
  • the present invention further relates to a combination of active substances for human and veterinary use, comprising colostral milk products and / or colostral milk extracts, also of bovine and / or equine origin, in solid, liquid or pasty form or also microencapsulated, in particular enclosed in liposomes; further comprising minerals and / or mineral salts, in particular obtained from the Dead Sea, and further comprising plant components and / or plant extracts, likewise in solid, liquid or pasty form or also microencapsulated, in particular used as a cosmetic, as a medicament, for prophylaxis and therapy Skin irritation of all kinds, as a food, as a food supplement or as a drink, also used as an additive for cosmetics, for medicines, food, food supplements and for beverages.
  • active substances for human and veterinary use comprising colostral milk products and / or colostral milk extracts, also of bovine and / or equine origin, in solid, liquid or pasty form or also microencapsulated, in particular enclosed
  • colostrum The basic components colostrum, minerals, in particular Dead Sea salt, and tea tree oil as a plant extract have so far been used individually in the skin area for skin irritation of all kinds.
  • the active ingredients contained in colostral milk can be taken internally as an extract or as Ointment to be applied externally.
  • the mineral active ingredients used in various skin diseases, especially psoriasis and neurodermatitis, are supplied to humans through a full salt bath through the skin. Not least because of this, sufferers of it travel to the Dead Sea to bathe.
  • the tea tree oil already known as a universal agent, can be used according to experimental studies and clinical studies for burns, mouth and gum infections, cuts and thrush infections. It is also known that colostrum ointment is an excellent remedy for burns and has the reddish spots healed within a very short time.
  • the filtered out colostrum extract or colostrum powder is, apart from small deviations in the substance content, fixed in its composition per liter.
  • Vitamin A ⁇ 150 ⁇ g / 100 ml
  • Vitamin C 270 ⁇ g / 100 ml
  • the mode of action of the colostrum has only been partially researched. So far, it has been found that the growth factors have a positive influence on the cell metabolism and increase the body's immune system.
  • the immunoglobulins support the immune system in preventing and warding off infections and are significantly anti-inflammatory.
  • the amino acids are vital protein building blocks for cellulose change and cell regeneration.
  • Colostrum has special healing properties with regard to skin therapy as a protective substance against bacteria, germs and fungi and leads to a strengthening of the skin tissue.
  • Dead Sea salt Minerals, especially Dead Sea salt, are already present in small amounts in colostral milk, but are not the main focus of colostrum in terms of their importance. In the case of a mixture of colostrum and especially Dead Sea salt, the Dead Sea salt also has its therapeutic effect due to the exceptionally high mine drop content. As with colostrum, the analysis of, for example, Dead Sea salt is fixed down to small deviations per kg.
  • Metal salts in particular obtained from the Dead Sea, are mostly used externally in humans or animals, for example as bath salts, as shampoos, etc. due to their mineral components.
  • Dead Sea salt is particularly valuable for the skin area because it is rich in magnesium and potassium.
  • Magnesium is known as an antiallergen, an important building block for the structural elements of the skin and the enzymes that control the metabolism of the skin. Potassium is an important moisture regulator for the skin. Iodine has a disinfectant and healing effect. Chlorine and sodium are electrolytes dissolved in water and play an important role in
  • Salt concentrations on the skin increases the production of free amino acids.
  • In the foreground of the reactions of the skin metabolism is the activation of proteolytic degradation processes of high-molecular protein compounds.
  • the resulting breakdown products are
  • Peptides with hormone-like effects so that ultimately the ions penetrating the skin can act on the interior of the organism, e.g. on the vascular system, the smooth muscles, on the digestive system and on the autonomic system.
  • the third active ingredient component, plant components and plant extracts also allows countless variation options for the new one due to the large number of plants with their diverse active ingredients in the phyto area
  • Active ingredient combination In particular, because in many cases not only the extract of a plant, but extracts from different plants, in different heights Concentrations, can be used.
  • Aloe Vera strengthens the skin's self-healing
  • avocado oil is soothing and soothing, eucalyptus, geranium, myrrh are antiseptic and antibacterial,
  • Jojoba oil is moisturizing and nourishing, chamomile and lavender are anti-inflammatory,
  • Peppermint oil is cooling and refreshing
  • Sunflower oil contains many vitamins A, D, B and E and has a nourishing effect, tea tree oil is draining and has an antibacterial effect.
  • Colostrum usually has the greatest effect when ingested and its effects are not so long-lasting when used externally.
  • the effect of the Dead Sea salt is particularly good for health when used externally.
  • Colostral milk products and / or colostral milk extracts if these are to be absorbed through the skin, are facilitated and substantially improved by the inventive combination with Dead Sea salt.
  • An improved absorption of the active ingredients of admixed plant extracts is also achieved in this way.
  • colostrum As a natural product, whose unique natural recipe is unlikely to be exactly imitated in laboratories, colostrum has all the vital nonessential and essential amino acids, immunoglobulins and natural growth factors along with vitamins, minerals and lactose and a large number of necessary building materials Fuel substances for the preservation and protection of life.
  • Minerals and / or mineral salts in particular Dead Sea salt as a mineral donor that is unique in the world, complement the minerals that do not contain or only to a small extent in colostrum by a further building block for health, which can affect the entire metabolism of humans, in particular through the skin .
  • the active ingredient combination according to the invention is supplemented by herbal extracts and extracts, and their various modes of action are also used.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

L'invention concerne un substance active destinée à l'homme et aux animaux, à base de colostrum d'origine humaine, ovine et/ou caprine, ainsi qu'une combinaison de substances actives. La combinaison comprend du colostrum et/ou des extraits de colostrum sous forme solide, fluide, pâteuse ou microencapsulée; des minéraux et des sels minéraux, provenant notamment de la Mer Morte; et des éléments et/ou des extraits végétaux, sous forme solide, fluide ou pâteuse. La composition peut s'utiliser en tant que produit cosmétique ou en tant que médicament, notamment pour la prophylaxie et le traitement dans le domaine cutané, comme soutien en cas d'infection, pour renforcer le système immunitaire, comme aliment, comme complément alimentaire et dans le domaine pharmaceutique, ou bien comme additif dans les aliments, les cosmétiques, les médicaments, les compléments alimentaires ou les boissons.
PCT/DE2000/000929 1999-03-31 2000-03-29 Substance active et combinaison de substances actives pour l'homme et les animaux WO2000059519A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00929249A EP1180940A2 (fr) 1999-03-31 2000-03-29 Substance active et combinaison de substances actives pour l'homme et les animaux
AU47426/00A AU4742600A (en) 1999-03-31 2000-03-29 Active agent and combination of active agents for human beings and animals

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19914646.2 1999-03-31
DE1999114646 DE19914646A1 (de) 1999-03-31 1999-03-31 Wirkstoffkombination für Mensch und Tier
DE19963628.1 1999-12-29
DE1999163628 DE19963628A1 (de) 1999-12-29 1999-12-29 Kolostralmilch von Ziegen und Schafen und deren Verwendung in Kosmetika, Pharmazeutika sowie in Nahrungs- und Nahrungsergänzungsmiteln
DE2000100157 DE10000157A1 (de) 2000-01-06 2000-01-06 Kolostralmilch (Erstmilch/Stillmilch) vom Menschen (HOMO SAPIENS) und deren Verwendung in Kosmetika, Pharmzeutika sowie in Nahrungs- und Nahrungsergänzungsmitteln
DE10000157.2 2000-01-06

Publications (2)

Publication Number Publication Date
WO2000059519A2 true WO2000059519A2 (fr) 2000-10-12
WO2000059519A3 WO2000059519A3 (fr) 2001-01-11

Family

ID=27213548

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/000929 WO2000059519A2 (fr) 1999-03-31 2000-03-29 Substance active et combinaison de substances actives pour l'homme et les animaux

Country Status (3)

Country Link
EP (1) EP1180940A2 (fr)
AU (1) AU4742600A (fr)
WO (1) WO2000059519A2 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003011241A1 (fr) * 2001-07-25 2003-02-13 Beiersdorf Ag Utilisation de creatinine et/ou de derives de la creatinine dans des preparations cosmetiques ou dermatologiques
WO2003011242A1 (fr) * 2001-07-25 2003-02-13 Beiersdorf Ag Preparations cosmetiques ou dermatologiques a combinaison de creatinine et/ou de derives de creatinine avec la creatinine et ou ses derives
US7033629B2 (en) 2001-08-31 2006-04-25 Nutricopia Inc. Nutritional frozen dessert and methods of manufacture
EP1727434A2 (fr) * 2004-03-19 2006-12-06 Nestec S.A. Administration des ingrédients fonctionnels
US7169416B2 (en) 2001-05-23 2007-01-30 Nutricopia, Inc. Nutritional frozen dessert and methods of manufacture
WO2007012647A1 (fr) * 2005-07-26 2007-02-01 Institut D'evaluation Dermatophysique Composition cosmetique pour la dermabrasion
US7557094B2 (en) * 2000-11-13 2009-07-07 Ethics Cosmeceuticals Ab Skin cream composition
US20100119531A1 (en) * 2005-05-02 2010-05-13 4Life Patents, Llc Nutriceutical gels
US9956258B2 (en) 2005-05-02 2018-05-01 4Life Patents, Llc Transfer factor preparations and associated methods

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG66186B1 (bg) * 2008-01-30 2011-12-30 Сийка ГЕОРГИЕВА Биологично активна хранителна добавка и метод за получаването и

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JPS553721A (en) * 1978-06-21 1980-01-11 Morinaga Milk Ind Co Ltd Production of powder of colostrum
US5750149A (en) * 1993-01-26 1998-05-12 Horse Vitality Ltd Pharmaceutical and dermocosmetic compositions containing equine colostrum
CN1105270A (zh) * 1994-01-14 1995-07-19 中国韬奋基金会 含分泌型免疫球蛋白a的制品及其制备方法
US5707678A (en) * 1995-04-12 1998-01-13 Galagen Inc. Method for microfiltration of milk or colostral whey
DE19619990A1 (de) * 1996-05-17 1997-11-20 Charlotte Adler Verfahren zur Herstellung von Kolostralmilchprodukten sowie deren Verwendung
IT1291340B1 (it) * 1997-05-09 1999-01-07 Vander Way Limited Formulazioni farmaceutiche contenenti colostro e uso del colostro per il trattamento di affezioni del cavo orale
WO1998053836A1 (fr) * 1997-05-27 1998-12-03 Anderson Michael R Produits gelifies ameliores contenant de l'oxygene actif
US5846569A (en) * 1997-06-20 1998-12-08 Creative Labs, Inc. Colostrum supplement

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Title
None

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7557094B2 (en) * 2000-11-13 2009-07-07 Ethics Cosmeceuticals Ab Skin cream composition
US7169416B2 (en) 2001-05-23 2007-01-30 Nutricopia, Inc. Nutritional frozen dessert and methods of manufacture
WO2003011241A1 (fr) * 2001-07-25 2003-02-13 Beiersdorf Ag Utilisation de creatinine et/ou de derives de la creatinine dans des preparations cosmetiques ou dermatologiques
WO2003011242A1 (fr) * 2001-07-25 2003-02-13 Beiersdorf Ag Preparations cosmetiques ou dermatologiques a combinaison de creatinine et/ou de derives de creatinine avec la creatinine et ou ses derives
US7033629B2 (en) 2001-08-31 2006-04-25 Nutricopia Inc. Nutritional frozen dessert and methods of manufacture
EP1727434A2 (fr) * 2004-03-19 2006-12-06 Nestec S.A. Administration des ingrédients fonctionnels
EP1727434B2 (fr) † 2004-03-19 2016-08-31 Nestec S.A. Administration des ingrédients fonctionnels
EP1727434B1 (fr) * 2004-03-19 2012-11-21 Nestec S.A. Administration des ingrédients fonctionnels
US20100119531A1 (en) * 2005-05-02 2010-05-13 4Life Patents, Llc Nutriceutical gels
US9028882B2 (en) * 2005-05-02 2015-05-12 4Life Patents, Llc Nutraceutical gels
US9956258B2 (en) 2005-05-02 2018-05-01 4Life Patents, Llc Transfer factor preparations and associated methods
US10363280B2 (en) 2005-05-02 2019-07-30 4Life Patents, Llc Nutraceutical gels
US10905732B2 (en) 2005-05-02 2021-02-02 4Life Patents, Llc Transfer factor preparations and associated methods
US11857593B2 (en) 2005-05-02 2024-01-02 4Life Patents, Llc Nutraceutical gels
FR2889058A1 (fr) * 2005-07-26 2007-02-02 Inst Evaluation Dermatophysiqu Composition cosmetique pour la dermabrasion
WO2007012647A1 (fr) * 2005-07-26 2007-02-01 Institut D'evaluation Dermatophysique Composition cosmetique pour la dermabrasion

Also Published As

Publication number Publication date
WO2000059519A3 (fr) 2001-01-11
EP1180940A2 (fr) 2002-02-27
AU4742600A (en) 2000-10-23

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