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WO1989005164A1 - Canule d'affluence pour pompes a sang intravasculaires - Google Patents

Canule d'affluence pour pompes a sang intravasculaires Download PDF

Info

Publication number
WO1989005164A1
WO1989005164A1 PCT/US1988/004295 US8804295W WO8905164A1 WO 1989005164 A1 WO1989005164 A1 WO 1989005164A1 US 8804295 W US8804295 W US 8804295W WO 8905164 A1 WO8905164 A1 WO 8905164A1
Authority
WO
WIPO (PCT)
Prior art keywords
cannula
tip
aortic valve
beveled
aortic
Prior art date
Application number
PCT/US1988/004295
Other languages
English (en)
Inventor
Richard K. Wampler
Original Assignee
Nimbus Medical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nimbus Medical, Inc. filed Critical Nimbus Medical, Inc.
Publication of WO1989005164A1 publication Critical patent/WO1989005164A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0069—Tip not integral with tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/135—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
    • A61M60/139—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting inside the aorta, e.g. intra-aortic balloon pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/408—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
    • A61M60/411—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
    • A61M60/414—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/857—Implantable blood tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/865—Devices for guiding or inserting pumps or pumping devices into the patient's body
    • A61M60/867—Devices for guiding or inserting pumps or pumping devices into the patient's body using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/32—General characteristics of the apparatus with radio-opaque indicia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices

Definitions

  • This invention relates to an inflow cannula for blind insertion of an intravascular blood pump, and more particularly to a cannula with a beveled tip which pushes the cannula to the center of the aortic valve for retrograde traversal.
  • U.S. Patent No. 4,625,712 and copending application Serial No.129, 714 filed 12/07/87 disclose miniature high-speed blood pumps which can be threaded through a blood vessel to provide heart assist in emergency situations without major surgery.
  • such pumps are inserted through, e.g., the femoral artery.
  • An inflow cannula is positioned ahead of the pump during insertion, and this cannula must typically be pushed through the aortic valve in a retrograde direction.
  • the present invention fulfills this requirement by providing a wire-reinforced silicon rubber cannula which has a spring-loaded curve built into it. This curve allows a reliable traverse of the aortic arch without getting the cannula caught in a major vessel such as, e.g., the left subclavian artery.
  • the cannula of this invention carries at its leading end a soft, beveled tip which is so positioned with respect to the built-in curve that the tip tends to point inwardly of the curve.
  • the soft, flexible tip As the soft, flexible tip approaches the aortic- valve, it contacts the sinuses of the valve on the inside of the arch and begins to fold upon itself. This action tends to push the body of the cannula," toward the center of the artery, and continued thrust of the cannula through the aorta causes the body of the cannula to penetrate through the aortic valve in an optimal position. After the cannula has entered the left ventricle, the flexible tip springs back to its original shape and allows blood to flow into the cannula without obstruction. Apertures are provided in the side of the cannula adjacent its leading end to prevent occlusion of the cannula intake by the flexible tip as a result of the pump's suction.
  • Fig. 1 is a schematic view illustrating the use of the invention in the arterial system of a patient
  • Fig. 2 is a plan view of the cannula of this invention.
  • Fig. 3 is a side elevation of the tip of the cannula of Fig. 2;
  • Figs . 4a through 4c are is a detail view of the centering and penetrating action of the cannula tip when it encounters and tranverses the aortic valve.
  • Fig. 1 shows, in schematic form, the environment in which the invention is used.
  • a miniature intravascular blood pump 10 is percutaneously inserted into the femoral artery (not shown) and is pushed through the femoral artery into the aorta 12 .
  • Rotary power for the cable drive 13 of pump 10 and purge fluid for its hydrostatic bearings is supplied through a catheter 14 from outside the patient's body, as described in more detail in copending application Ser. No. filed .
  • the cannula 16 of this . invention is attached to the forward (i.e. intake) end of the pump 10 and guides it through the patient's arterial system during insertion.
  • the blood intake in the left ventricle 17 of the heart i.e. the leading end of the inflow cannula 16 must be passed through the aortic valve 18.
  • the cannula 16 must follow the aortic arch 20 smoothly without getting caught in one of the major arteries 24 branching off from the aorta 12 in the arch 20.
  • the cannula 16 must be substantially centered in the aorta 13 as it approaches the aortic valve 18 so as not to get caught in or injure the sinuses 28 (Fig.
  • Figs . 2 and 3 show the inventive cannula structure which accomplishes these results.
  • the cannula 16 is formed from a tube 32 of soft silicon rubber which, in its body- section 34, covers a spring 36.
  • the tip section 38 of the cannula 16 beyond the leading end of spring 36 is beveled for a purpose described below.
  • a radioopaque strip 40 may be interposed between the tube 32 and the spring 36, and extended to the leading end of the tip section 38, for x-ray tracking of the cannula insertion when x-ray equipment is available.
  • forming techniques are employed to bias the body section 34 of cannula 16 into the arcuate shape best illustrated in Fig. 2. This bias urges the cannula 16 to follow the curve of the aortic arch 20 upon insertion and keeps it away from the branch arteries while it traverses the aortic arch.
  • the loading imposed by spring 36 is weak enough to allow the body section 34 to be straightened by the walls of the arteries when it traverses a straight section of artery.
  • the body section 34 On each end of its arcuate portion, the body section 34 has short straight portions 42,44.
  • the trailing straight portion 42 may be attached to the intake end of pump 10 in any conventional manner, and the leading straight portion 44 allows the intake opening 46 to remain centered in the left ventricle 17 (Fig. 1) after traversing the aortic valve 18.
  • its diameter may be on the order of 7 mm; the arcuate portion of the body section 34 may have a radius on the order of 2.5 cm; the straight portion 42 may be on the order of 10 cm long; and the straight portion 44 may have a length on the order of 4 mm, not counting the 4 cm-long tip section 38.
  • the tip section 38 is beveled at about a 20° angle at its leading end/
  • a pair of auxiliary openings 48 are provided in the side of tip section 38 for a purpose discussed below.
  • Fig. 4b shows in more detail what happens as the tip section 38 contacts the aortic valve 18 ⁇ when moving in the direction of rrow 49.
  • the soft beveled end 50 of tip section 38 is not strong enough to penetrate or push aside the aortic leaflets 30; consequently, it resiliently collapses. In doing so, it follows the curve of the aortic leaflet 30 against which it has impinged until it is stopped by the wall of the aorta 13 at sinus 28. Once stopped, further collapse of the beveled portion 50 of tip section 38 causes the body section 34 of cannula 16 to be pushed toward the center of the aorta 13. Continued insertion of the cannula 16 will therefore cause the cannula 16 to traverse the aortic valve 18 dead center, eliminating the risk of its getting caught in, and damaging., the sinus 28.
  • the soft beveled tip portion 50 folds over the intake opening 46 of cannula 16 and follows the leading end of the body section 34 into the left ventricle 17.
  • the beveled tip portion 50 has passed entirely through the aortic valve 18, its resiliency causes it to spring back to is original shape where it leaves the intake opening 46 unobstructed (Fig. 4c) .
  • auxiliary openings 48 are provided in the side of the tip section 38.
  • the auxiliary openings 48 provide a sufficient bypass flow path to allow the inherent resilience of the tip section 38 to overcome any suction force at the intake opening 46, even if the pump 10 is operating at maximum speed.
  • the auxiliary openings 48 are preferably so positioned that their axes are parallel to the beveling plane of the beveled tip portion 50. In this manner, the beveled tip portion 50 is prevented from obstructing either auxiliary opening 48 during its passage through the aortic valve 18.
  • the present invention provides an inflow cannula for intravascular pumps which is suitable for rapid, blind retrograde insertion into the left ventricle of a human heart when immediate heart assist is called for in emergencies or other situations.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • External Artificial Organs (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Canule d'affluence pour pompes à sang intraortiques (10) comportant un corps courbé à ressort permettant l'insertion rétrograde san visibilité à travers l'arc aortique (20), ainsi qu'un bout mou biseauté pliant mais élastique (38) lequel centre le bout par rapport à la valvule aortique (18) avant l'insertion rétrograde de l'extrémité distale de la canule (16) à travers ladite valvule aortique (18). Des orifices d'admission auxiliaires (48) sont prévus dans les parois latérales de la canule (16), adjacents à son extrémité distale, afin d'empêcher l'aspiration de maintenir le bout (38) dans son état plié, après insertion à travers la valvule aortique (18).
PCT/US1988/004295 1987-12-07 1988-12-02 Canule d'affluence pour pompes a sang intravasculaires WO1989005164A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12971387A 1987-12-07 1987-12-07
US129,713 1987-12-07

Publications (1)

Publication Number Publication Date
WO1989005164A1 true WO1989005164A1 (fr) 1989-06-15

Family

ID=22441233

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1988/004295 WO1989005164A1 (fr) 1987-12-07 1988-12-02 Canule d'affluence pour pompes a sang intravasculaires

Country Status (2)

Country Link
AU (1) AU2807389A (fr)
WO (1) WO1989005164A1 (fr)

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001017581A2 (fr) 1999-09-03 2001-03-15 A-Med Systems, Inc. Pompe a sang intravasculaire pouvant etre guidee et procedes s"y rapportant
US6936222B2 (en) 2002-09-13 2005-08-30 Kenneth L. Franco Methods, apparatuses, and applications for compliant membrane blood gas exchangers
US7731675B2 (en) 1999-09-03 2010-06-08 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US8376707B2 (en) 2004-09-17 2013-02-19 Thoratec Corporation Expandable impeller pump
US8485961B2 (en) 2011-01-05 2013-07-16 Thoratec Corporation Impeller housing for percutaneous heart pump
US8535211B2 (en) 2009-07-01 2013-09-17 Thoratec Corporation Blood pump with expandable cannula
US8591393B2 (en) 2011-01-06 2013-11-26 Thoratec Corporation Catheter pump
US8597170B2 (en) 2011-01-05 2013-12-03 Thoratec Corporation Catheter pump
US9138518B2 (en) 2011-01-06 2015-09-22 Thoratec Corporation Percutaneous heart pump
US9308302B2 (en) 2013-03-15 2016-04-12 Thoratec Corporation Catheter pump assembly including a stator
US9327067B2 (en) 2012-05-14 2016-05-03 Thoratec Corporation Impeller for catheter pump
US9358329B2 (en) 2012-07-03 2016-06-07 Thoratec Corporation Catheter pump
US9364593B2 (en) 2004-09-17 2016-06-14 The Penn State Research Foundation Heart assist device with expandable impeller pump
US9381288B2 (en) 2013-03-13 2016-07-05 Thoratec Corporation Fluid handling system
US9421311B2 (en) 2012-07-03 2016-08-23 Thoratec Corporation Motor assembly for catheter pump
US9446179B2 (en) 2012-05-14 2016-09-20 Thoratec Corporation Distal bearing support
US9675740B2 (en) 2012-05-14 2017-06-13 Tc1 Llc Impeller for catheter pump
US9675738B2 (en) 2015-01-22 2017-06-13 Tc1 Llc Attachment mechanisms for motor of catheter pump
US9675739B2 (en) 2015-01-22 2017-06-13 Tc1 Llc Motor assembly with heat exchanger for catheter pump
US9770543B2 (en) 2015-01-22 2017-09-26 Tc1 Llc Reduced rotational mass motor assembly for catheter pump
US9827356B2 (en) 2014-04-15 2017-11-28 Tc1 Llc Catheter pump with access ports
US9872947B2 (en) 2012-05-14 2018-01-23 Tc1 Llc Sheath system for catheter pump
US9907890B2 (en) 2015-04-16 2018-03-06 Tc1 Llc Catheter pump with positioning brace
US10029037B2 (en) 2014-04-15 2018-07-24 Tc1 Llc Sensors for catheter pumps
US10105475B2 (en) 2014-04-15 2018-10-23 Tc1 Llc Catheter pump introducer systems and methods
KR20200020792A (ko) 2017-06-21 2020-02-26 아비오메드 유럽 게엠베하 혈관내 혈액 펌프용 캐뉼라
US10583232B2 (en) 2014-04-15 2020-03-10 Tc1 Llc Catheter pump with off-set motor position
US11077294B2 (en) 2013-03-13 2021-08-03 Tc1 Llc Sheath assembly for catheter pump
US11219756B2 (en) 2012-07-03 2022-01-11 Tc1 Llc Motor assembly for catheter pump
US11229786B2 (en) 2012-05-14 2022-01-25 Tc1 Llc Impeller for catheter pump
US11850414B2 (en) 2013-03-13 2023-12-26 Tc1 Llc Fluid handling system

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US4033331A (en) * 1975-07-17 1977-07-05 Guss Stephen B Cardiac catheter and method of using same
US4469483A (en) * 1982-08-25 1984-09-04 Baxter Travenol Laboratories, Inc. Radiopaque catheter
US4508535A (en) * 1982-04-10 1985-04-02 Nippon Zeon Co., Ltd. Cannula
US4588399A (en) * 1980-05-14 1986-05-13 Shiley Incorporated Cannula with radiopaque tip
US4625712A (en) * 1983-09-28 1986-12-02 Nimbus, Inc. High-capacity intravascular blood pump utilizing percutaneous access
US4639252A (en) * 1985-04-05 1987-01-27 Research Medical, Inc. Venous return catheter
US4737153A (en) * 1986-02-07 1988-04-12 Kuraray Co., Ltd. Reinforced therapeutic tube
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Publication number Priority date Publication date Assignee Title
DE823320C (de) * 1950-08-15 1951-12-03 Willy Ruesch Katheter, insbesondere Intratracheal-Katheter und Verfahren zu seiner Herstellung
US4033331A (en) * 1975-07-17 1977-07-05 Guss Stephen B Cardiac catheter and method of using same
US4588399A (en) * 1980-05-14 1986-05-13 Shiley Incorporated Cannula with radiopaque tip
US4508535A (en) * 1982-04-10 1985-04-02 Nippon Zeon Co., Ltd. Cannula
US4469483A (en) * 1982-08-25 1984-09-04 Baxter Travenol Laboratories, Inc. Radiopaque catheter
US4625712A (en) * 1983-09-28 1986-12-02 Nimbus, Inc. High-capacity intravascular blood pump utilizing percutaneous access
US4639252A (en) * 1985-04-05 1987-01-27 Research Medical, Inc. Venous return catheter
US4737153A (en) * 1986-02-07 1988-04-12 Kuraray Co., Ltd. Reinforced therapeutic tube
US4753221A (en) * 1986-10-22 1988-06-28 Intravascular Surgical Instruments, Inc. Blood pumping catheter and method of use

Cited By (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9789238B2 (en) 1999-09-03 2017-10-17 Maquet Cardiovascular, Llc Guidable intravascular blood pump and related methods
US10357598B2 (en) 1999-09-03 2019-07-23 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
WO2001017581A2 (fr) 1999-09-03 2001-03-15 A-Med Systems, Inc. Pompe a sang intravasculaire pouvant etre guidee et procedes s"y rapportant
EP1207934A4 (fr) * 1999-09-03 2009-09-02 A Med Systems Inc Pompe a sang intravasculaire pouvant etre guidee et procedes s'y rapportant
US7731675B2 (en) 1999-09-03 2010-06-08 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US10328191B2 (en) 1999-09-03 2019-06-25 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US10238783B2 (en) 1999-09-03 2019-03-26 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US10322218B2 (en) 1999-09-03 2019-06-18 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US10300186B2 (en) 1999-09-03 2019-05-28 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
EP1207934A2 (fr) * 1999-09-03 2002-05-29 A-Med Systems, Inc. Pompe a sang intravasculaire pouvant etre guidee et procedes s'y rapportant
US8888728B2 (en) 1999-09-03 2014-11-18 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US10279095B2 (en) 1999-09-03 2019-05-07 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9597437B2 (en) 1999-09-03 2017-03-21 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9561314B2 (en) 1999-09-03 2017-02-07 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9545468B2 (en) 1999-09-03 2017-01-17 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US10300185B2 (en) 1999-09-03 2019-05-28 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US9327068B2 (en) 1999-09-03 2016-05-03 Maquet Cardiovascular Llc Guidable intravascular blood pump and related methods
US6936222B2 (en) 2002-09-13 2005-08-30 Kenneth L. Franco Methods, apparatuses, and applications for compliant membrane blood gas exchangers
US8409502B2 (en) 2002-09-13 2013-04-02 Kenneth L. Franco Methods, apparatuses, and applications for compliant membrane blood gas exchangers
US9364593B2 (en) 2004-09-17 2016-06-14 The Penn State Research Foundation Heart assist device with expandable impeller pump
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