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US8777031B2 - Stopper device comprising a supporting cap, and container device provided with such a device - Google Patents

Stopper device comprising a supporting cap, and container device provided with such a device Download PDF

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Publication number
US8777031B2
US8777031B2 US12/866,100 US86610009A US8777031B2 US 8777031 B2 US8777031 B2 US 8777031B2 US 86610009 A US86610009 A US 86610009A US 8777031 B2 US8777031 B2 US 8777031B2
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US
United States
Prior art keywords
cover
neck
stopper
container
ring
Prior art date
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Application number
US12/866,100
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English (en)
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US20110000872A1 (en
Inventor
Antoine Aneas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
West Pharmaceutical Services Deutschland GmbH and Co KG
Original Assignee
West Pharmaceutical Services Deutschland GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Assigned to BIOCORP RECHERCHE ET DEVELOPPEMENT reassignment BIOCORP RECHERCHE ET DEVELOPPEMENT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ANEAS, ANTOINE
Publication of US20110000872A1 publication Critical patent/US20110000872A1/en
Assigned to WEST PHARMACEUTICAL SERVICES DEUTSCHLAND GMBH & CO. KG reassignment WEST PHARMACEUTICAL SERVICES DEUTSCHLAND GMBH & CO. KG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BIOCORP RECHERCHE ET DEVELOPPEMENT
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Publication of US8777031B2 publication Critical patent/US8777031B2/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/24Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/241Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes provided with freeze-drying means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D45/00Clamping or other pressure-applying devices for securing or retaining closure members
    • B65D45/32Clamping or other pressure-applying devices for securing or retaining closure members for applying radial or radial and axial pressure, e.g. contractible bands encircling closure member
    • B65D45/322Clamping or other pressure-applying devices for securing or retaining closure members for applying radial or radial and axial pressure, e.g. contractible bands encircling closure member the clamping device being an annular member moved axially to clamp the closure by using radial pressure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/18Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00Details relating to container closures
    • B65D2251/0003Two or more closures
    • B65D2251/0006Upper closure
    • B65D2251/0028Upper closure of the 51-type
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00Details relating to container closures
    • B65D2251/0003Two or more closures
    • B65D2251/0068Lower closure
    • B65D2251/0075Lower closure of the 39-type

Definitions

  • the invention relates to a stopper device for stopping a container provided with a neck, and it also relates to a container equipped with such a device.
  • a glass bottle can be used to store an active ingredient in freeze-dried form, in powder form, or in the form of a liquid solution. Such a bottle must be closed off in leaktight manner so as to maintain its content in a satisfactory state of preservation, until the date on which it is used.
  • a stopper device can be used that comprises an elastomer stopper that has the function of being totally sealed against gas, liquids, and bacteria.
  • Such a device further comprises a locking cover that, as mentioned in FR 2 900 131, U.S. Pat. No. 5,678,719 or U.S. Pat. No. 5,421,469, can be made of a plastics material, and that is designed to be held in place around the stopper so as to isolate it from the outside and so as to oppose removal of it.
  • each container is filled with a quantity of substance for freeze-drying, and then the respective stopper is placed on or in the neck of the container in such a manner as to be secured thereto while also preserving communication between the outside environment and the inside of the container.
  • Containers filled and pre-stopped in this way are then placed in batches on the shelves of a freeze drier inside which the substances are dehydrated.
  • vacuum cold-drying is performed that guarantees that the water is extracted from the substance by sublimation and evaporation.
  • a object of the invention is, more particularly, to remedy those drawbacks by proposing a stopper device by means of which a force for locking a cover can be transmitted effectively, even when account is taken of the manufacturing tolerances of the bottles, of the stoppers, of the component parts of a cover, and of the mechanical members for applying the force.
  • the invention relates to a stopper device for stopping a container having a neck of axis ⁇ , said device comprising:
  • the stopper device is characterized in that firstly the connecting web is elastically deformable in a manner such that, under the effect of an axial force, it enables the press rim to be moved axially from a raised position R towards a lowered position A via an intermediate position I, and secondly, over a first deformation range, corresponding to the press rim being moved from the raised position R to the intermediate position I, said connecting web has a stiffness K 1 greater than the stiffness K 2 of the web over a second deformation range corresponding to the press rim being moved from the intermediate position I to the lowered position A.
  • the connecting web is adapted so that, while the press rim is moving from the raised position, said press rim exerts an increasing reaction that decreases after it has reached a maximum value at the intermediate position.
  • the value of the axial pressure to be applied to the press rim of the cap in order to cause it to go from its raised position to its intermediate position is greater than the force necessary for engaging the stopper into the neck of the container with the cover being locked to the neck.
  • Such a value for the stiffness of the connecting web makes it possible to guarantee that the press rim is lowered only once the stopper is properly engaged and once the cover is locked to the neck of the container.
  • only the raised position of the press rim is a stable position so that, in the event that the axial force ceases to be applied, the press rim returns automatically to its raised position.
  • the locking means of the cover may be implemented in various manners and, for example, comprise locking fingers that are integral with the cover.
  • the locking means may be separate and mounted on or in the cover.
  • the locking means comprise a ring that is placed at least in part inside the cover and that has an annular ceiling and a peripheral band that is integral with the annular ceiling and from which there extend at least two elastically deformable tongues that, opposite from the band, have respective locking ends designed to engage under the neck of the container.
  • a locking ring makes it possible to facilitate manufacture of the cover, while imparting a good external appearance to it.
  • this embodiment makes it possible to dissociate clearly the stage of pushing in the stopper from the stage of locking the cover to the neck of the container, thereby avoiding cumulative stresses resulting from pushing in the stopper and from locking the cover.
  • each tongue extends away from the annular ceiling in a direction that is substantially axial, its locking end being curved over inwards to define a catch designed to come into abutment under the neck of the container.
  • the inside face of the distal portion of each tongue is shaped to come into abutment against the neck of the container in the locking position.
  • each tongue that forms its catch is reinforced.
  • At least one of the tongues has, on the outside face of a proximal portion, an assembly rib designed to co-operate with the blocking recess to couple the ring to the cover before the cover is engaged fully over the ring.
  • each tongue extends towards the annular ceiling from the peripheral rim while extending towards the inside of the ring.
  • the cover has a skirt that, at an end opposite from the cap, is provided with blocking means for blocking movement of the tongues when the cover is fully engaged over the ring.
  • the ring has an outer annular belt designed to surround the skirt of the cover when the cover is fully engaged over the ring.
  • the cover is provided with locking means designed to co-operate with complementary locking means of the annular belt when the cover is fully engaged over the ring in such a manner as to oppose removal of the cover.
  • the invention also relates to a container equipped with a stopper device of the invention.
  • FIG. 2 is an axial section view of the cover of the stopper device shown in FIG. 1 ;
  • FIG. 7 is a graph showing the value of the axial force exerted on or by the press rim during pushing-in of the stopper followed by locking of the cover, with, along the abscissa axis, the movement of the press rim expressed in millimeters, and, up the ordinate axis, the absolute value of the axial force expressed in newtons;
  • FIG. 8 is a partially cutaway perspective view of a variant embodiment of the stopper device of the invention.
  • the stopper device also includes a cover made of a plastics material 10 that is suitable for covering both the neck C and the stopper 2 in place in the neck C as shown in FIGS. 5 and 6 .
  • the cover 10 is provided with locking means 11 for locking it to the neck.
  • the cover 10 has a peripheral skirt 12 that is substantially cylindrical in general shape and of axis ⁇ .
  • the cover 10 also has a top 13 that is integral with the skirt 12 and that is provided with a through axial bore 14 .
  • each tongue 19 is curved over towards the inside of the ring 11 so as to define a catch 21 designed to engage under the neck C of the container R as appears below.
  • the catch 21 of each tongue is thicker or reinforced relative to the remainder of the tongue in such a manner as to present good resistance to being pulled off.
  • a distal portion 22 of each tongue extends outwards and has, on its outside face, a blocking lug 23 designed to co-operate with a complementary blocking recess 24 in the cover 10 when said cover is fully engaged over the locking ring.
  • the complementary recess 24 is in the form of an annular groove provided inside the skirt 12 of the cover 10 and in the vicinity of a bottom end thereof.
  • At least one and, in the example shown, four, tongues are provided with respective assembly ribs 25 on the outside faces of respective proximal portions of the tongues, which ribs are designed to co-operate with the blocking recess (the groove 24 in this example) to couple the ring 11 to cover 10 before the cover 10 is fully engaged over the ring 11 , as shown more particularly in FIGS. 1 and 2 .
  • FIG. 3 it can be observed that, in FIG. 3 , only two of the four assembly ribs 25 are visible, while, in FIGS. 1 , 2 , and 4 to 6 , only one of the assembly ribs 25 is visible.
  • the stopper device 1 of the invention also includes a cap 30 that has a central or axial stud 31 engaged in the axial bore 14 in such a manner as to couple the cap 30 to the cover 10 .
  • the cap 30 closes off the axial bore 14 and, before it is removed, opposes any access to the stopper 2 via the bore 14 and via the opening 18 .
  • the cap 30 also has a peripheral press rim 32 that is connected to the stud 31 via at least one, and, in the example shown, exactly one, connecting web 33 that is elastically deformable in such a manner as to enable the press rim 32 to move axially under drive from an axial force.
  • the press rim is mounted to move between a raised position R shown in FIG.
  • the web 33 is adapted so that the raised position R is a stable position whereas the other positions are unstable positions. By means of this characteristic, the press rim automatically returns to the raised position R when stress ceases to be applied to it.
  • the stopper device 1 as constituted in this way, is used in the following manner.
  • the stopper 2 is engaged in part in the neck of the container B as shown in FIG. 1 , and the assembly formed by the locking ring 11 , by the cover 10 , and by the cap 30 is positioned over the stopper 2 , the ceiling 17 of the ring 11 coming into abutment against the head 4 of the stopper 2 .
  • the container B equipped in this way is then placed inside a freeze drier (not shown) with other identical containers that are identically equipped, for the purposes of having their contents dehydrated in said freeze drier.
  • the stopper device 1 is designed in such a manner that, in its semi-engaged position, as shown in FIG.
  • the set of containers equipped with the stopper devices 1 of the invention and disposed inside the freeze drier can be stopped in final manner.
  • pressure is applied on the press rim 32 in the direction indicated by arrow F 1 by means of a presser plate P shown diagrammatically in chain-dotted lines in FIGS. 1 and 4 to 6 .
  • this pressure F 1 causes the stopper to be pushed fully into the neck of the container until the head 4 is brought into abutment against said neck C, as is shown in FIG. 4 .
  • the curved-over ends 21 of the tongues 20 are far enough apart not to interfere with the neck of the container B, or not to interfere very much therewith, in such a manner as not to increase the stresses necessary to push in the stopper 4 .
  • FIG. 7 shows the value of the force exerted on or by the press rim 32 of the stopper device 1 as a function of the movement of said press rim 32 .
  • the push-in stage as described above corresponds substantially to the first portion I of the curve.
  • the force on the press rim 32 is maintained, as shown in the second portion II of the curve, in such a manner as to guarantee that the cover 10 is engaged over the locking ring 11 .
  • the assembly ribs 25 disengage from the annular groove 24 , zone IIa of the curve, then the locking ends 21 of the tongues 20 move inwards under the neck C as shown in FIG. 5 , corresponding to zone IIb of the curve.
  • the cover 10 continues to be pushed until the blocking lugs 23 are brought into the groove 24 as shown in FIG. 5 , corresponding to zone IIc of the curve.
  • the stopper device 1 of the invention is securely locked to the container B so that it closes the container in securely leaktight manner.
  • the web 33 is designed in such a manner that the force necessary for bringing the press rim 32 from the raised position R to the intermediate position I is greater than the force that it is necessary to exert to push in the stopper 2 fully, with the ring 11 and the cover 10 also being locked.
  • the press rim 32 is in the raised position R, in the stage corresponding to portion IIIa of the curve, the press rim 32 goes from the raised position R to the intermediate position I, and then in the stage corresponding to portion IIIb of the curve, the press rim 32 moves from the intermediate position I to the lowered position A.
  • the last portion IIIc of the curve corresponds to when the force continues to be exerted on the press rim 32 , the movement of the plate corresponding to elastic compression of the press rim 32 and of the various component parts of the stopper device 1 .
  • the peripheral band 34 of the cap 30 has at least one and, in the example shown, four, vents 35 , two of which are visible in FIG. 3 .
  • peripheral band 34 is provided with a series of spikes or pieces of roughness 36 distributed around its periphery in order to facilitate taking hold of the cap 30 for pulling it off in order to make it possible to draw off the content of the container B, e.g. by using a syringe having its needle plunged through the head 4 of the stopper 2 .
  • the skirt 10 in order to avoid any conflict between the skirt 10 and the assembly ribs 25 in the locking position as shown in FIG. 5 , the skirt 10 is provided with an intermediate groove 41 into which the assembly ribs 25 come to be positioned once the cover 10 is fully engaged over the locking ring 11 , as shown in FIG. 5 .
  • each tongue 20 is, in the locked position, substantially in abutment against the neck C of the container B, while the outside face of each tongue presents, in axial section, a generally V-shaped configuration.
  • Such an arrangement causes each tongue 20 to brace itself against any pull-off stress that is exerted on the cover 10 or on the catches 21 of the tongues 20 , given that the stopper device of the invention is also locked to the neck C of the container B.
  • cover 10 and the associated locking means may be made in a manner entirely different from the manner described above with reference to FIGS. 1 to 6 .
  • FIG. 8 shows another embodiment of a stopper device 1 in which the tongues 20 extend upwards towards the annular ceiling 13 from the peripheral band 19 .
  • the ring 11 further includes an outer annular belt 45 that co-operates with the band 19 to define an annular recess 46 into which the skirt 12 of the cover 10 is engaged.
  • the bottom end of the skirt 12 that is opposite from the cap 30 has a shape that defines blocking means for blocking movement of the tongues 20 when the cover is fully engaged over the ring 10 .
  • the skirt 12 of the cover 10 is provided with locking means in the form of a peripheral lip 47 designed to co-operate with complementary locking means with which the belt 46 is provided, which locking means are, in this example, constituted by an annular groove 48 .
  • the locking means 47 and 48 prevent any untimely removal of the cover 10 once said cover has been engaged over the locking ring 11 .
  • the press rim 32 and the connecting web 33 are monostable, the press rim returning automatically to the raised position R when no stress is applied to it.
  • the connecting web 33 may be designed so that the press rim 32 is bistable. In which case, when the press rim goes beyond the intermediate position I, it goes spontaneously into the lowered position A. Thus, only the raised position R and the lowered position A of the press rim 32 are stable positions.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
US12/866,100 2008-02-11 2009-02-10 Stopper device comprising a supporting cap, and container device provided with such a device Active 2031-11-15 US8777031B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0850837A FR2927316B1 (fr) 2008-02-11 2008-02-11 Dispositif de bouchage a chapeau d'appui et recipient equipe d'un tel dispositif
FR0850837 2008-02-11
PCT/FR2009/050209 WO2009101354A1 (fr) 2008-02-11 2009-02-10 Dispositif de bouchage à chapeau d'appui et récipient équipé d'un tel dispositif

Publications (2)

Publication Number Publication Date
US20110000872A1 US20110000872A1 (en) 2011-01-06
US8777031B2 true US8777031B2 (en) 2014-07-15

Family

ID=39766879

Family Applications (1)

Application Number Title Priority Date Filing Date
US12/866,100 Active 2031-11-15 US8777031B2 (en) 2008-02-11 2009-02-10 Stopper device comprising a supporting cap, and container device provided with such a device

Country Status (12)

Country Link
US (1) US8777031B2 (ja)
EP (1) EP2242701B1 (ja)
JP (1) JP5364869B2 (ja)
CN (1) CN101952179B (ja)
AU (1) AU2009213918A1 (ja)
CA (1) CA2714618A1 (ja)
CY (1) CY1113066T1 (ja)
ES (1) ES2387600T3 (ja)
FR (1) FR2927316B1 (ja)
MX (1) MX2010008842A (ja)
PL (1) PL2242701T3 (ja)
WO (1) WO2009101354A1 (ja)

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US10959553B2 (en) 2016-10-17 2021-03-30 Yeti Coolers, Llc Container and method of forming a container
US10959552B2 (en) 2016-10-17 2021-03-30 Yeti Coolers, Llc Container and method of forming a container
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US11034505B2 (en) 2016-10-17 2021-06-15 Yeti Coolers, Llc Container and method of forming a container
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US11469007B2 (en) 2018-03-09 2022-10-11 Robert Kamen Compression member for biohazardous material transporting pig
IT202200013321A1 (it) * 2022-06-23 2023-12-23 Capsulit Srl Dispositivo di chiusura, particolarmente per flaconi di prodotti liofilizzati, e procedimento per chiudere un flacone di prodotti liofilizzati.
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JP2011511741A (ja) 2011-04-14
CN101952179A (zh) 2011-01-19
FR2927316B1 (fr) 2010-05-14
US20110000872A1 (en) 2011-01-06
JP5364869B2 (ja) 2013-12-11
FR2927316A1 (fr) 2009-08-14
MX2010008842A (es) 2010-09-09
PL2242701T3 (pl) 2012-10-31
CA2714618A1 (fr) 2009-08-20
CY1113066T1 (el) 2016-04-13
WO2009101354A1 (fr) 2009-08-20
AU2009213918A1 (en) 2009-08-20
CN101952179B (zh) 2012-02-22
EP2242701A1 (fr) 2010-10-27
EP2242701B1 (fr) 2012-06-20
ES2387600T3 (es) 2012-09-27

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