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TWI541023B - 在生理ph緩衝液中呈現增強之溶解度及穩定性之升糖激素類似物 - Google Patents

在生理ph緩衝液中呈現增強之溶解度及穩定性之升糖激素類似物 Download PDF

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Publication number
TWI541023B
TWI541023B TW098120168A TW98120168A TWI541023B TW I541023 B TWI541023 B TW I541023B TW 098120168 A TW098120168 A TW 098120168A TW 98120168 A TW98120168 A TW 98120168A TW I541023 B TWI541023 B TW I541023B
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Taiwan
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amino acid
peptide
glucosamine
seq
acid
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TW098120168A
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English (en)
Chinese (zh)
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TW201010730A (en
Inventor
理查D 迪瑪奇
大衛L 席邁里
瑪利亞 迪瑪奇
喬瑟夫 錢班尼
喬那森 迪
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印第安納大學科技研究公司
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Publication of TW201010730A publication Critical patent/TW201010730A/zh
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW098120168A 2008-06-17 2009-06-16 在生理ph緩衝液中呈現增強之溶解度及穩定性之升糖激素類似物 TWI541023B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7319308P 2008-06-17 2008-06-17
US7816508P 2008-07-03 2008-07-03
US9041508P 2008-08-20 2008-08-20

Publications (2)

Publication Number Publication Date
TW201010730A TW201010730A (en) 2010-03-16
TWI541023B true TWI541023B (zh) 2016-07-11

Family

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TW098120168A TWI541023B (zh) 2008-06-17 2009-06-16 在生理ph緩衝液中呈現增強之溶解度及穩定性之升糖激素類似物

Country Status (12)

Country Link
US (1) US8450270B2 (ko)
EP (1) EP2307037A4 (ko)
JP (2) JP5753779B2 (ko)
KR (1) KR20110039230A (ko)
CN (2) CN102088989B (ko)
AU (1) AU2009260301B2 (ko)
CA (1) CA2727161A1 (ko)
IL (1) IL209287A (ko)
MX (1) MX2010012695A (ko)
RU (1) RU2560254C2 (ko)
TW (1) TWI541023B (ko)
WO (1) WO2009155257A1 (ko)

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