TW251274B - - Google Patents
Info
- Publication number
- TW251274B TW251274B TW082108452A TW82108452A TW251274B TW 251274 B TW251274 B TW 251274B TW 082108452 A TW082108452 A TW 082108452A TW 82108452 A TW82108452 A TW 82108452A TW 251274 B TW251274 B TW 251274B
- Authority
- TW
- Taiwan
- Prior art keywords
- alkyl
- aryl
- hydrogen
- group
- dipeptide
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 108010016626 Dipeptides Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000006242 amine protecting group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 150000001735 carboxylic acids Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Detergent Compositions (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/931,809 US5442100A (en) | 1992-08-14 | 1992-08-14 | β-aminoalkyl and β-N-peptidylaminoalkyl boronic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
TW251274B true TW251274B (zh) | 1995-07-11 |
Family
ID=25461390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW082108452A TW251274B (zh) | 1992-08-14 | 1993-10-13 |
Country Status (10)
Country | Link |
---|---|
US (2) | US5442100A (zh) |
EP (1) | EP0655067B1 (zh) |
JP (1) | JPH08500113A (zh) |
CN (1) | CN1047596C (zh) |
AT (1) | ATE159945T1 (zh) |
AU (1) | AU4799793A (zh) |
DE (1) | DE69315079T2 (zh) |
MX (1) | MX9304970A (zh) |
TW (1) | TW251274B (zh) |
WO (1) | WO1994004542A1 (zh) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69217935T2 (de) * | 1992-08-14 | 1997-10-09 | Procter & Gamble | Alpha-aminoborsäurehaltige flüssige Waschmittel |
EP0707642A1 (en) * | 1993-07-09 | 1996-04-24 | Novo Nordisk A/S | Boronic acid or borinic acid derivatives as enzyme stabilizers |
US5834415A (en) * | 1994-04-26 | 1998-11-10 | Novo Nordisk A/S | Naphthalene boronic acids |
DE4422433A1 (de) * | 1994-06-28 | 1996-01-04 | Cognis Bio Umwelt | Mehrenzymgranulat |
US5731439A (en) * | 1995-03-24 | 1998-03-24 | The Dupont Merck Pharmaceutical Company | Piperidine containing aminobornic acids |
CA2221635A1 (en) | 1995-06-05 | 1996-12-12 | Creative Products Resource, Inc. | Dry-cleaning kit for in-dryer use |
US5658651A (en) | 1995-09-29 | 1997-08-19 | Creative Products Resource, Inc. | Fabric treatment and softener system for in-dryer use |
US6086634A (en) | 1995-06-05 | 2000-07-11 | Custom Cleaner, Inc. | Dry-cleaning compositions containing polysulfonic acid |
US6036727A (en) | 1995-06-05 | 2000-03-14 | Creative Products Resource, Inc. | Anhydrous dry-cleaning compositions containing polysulfonic acid, and dry-cleaning kits for delicate fabrics |
KR100426438B1 (ko) * | 1995-06-13 | 2004-06-30 | 노보자임스 에이/에스 | 효소안정화제로서의4-치환-페닐-보론산 |
US6727368B1 (en) * | 1999-06-14 | 2004-04-27 | Wisconsin Alumni Research Foundation | Oligomers and polymers of cyclic imino carboxylic acids |
US20060063690A1 (en) * | 2004-09-08 | 2006-03-23 | Billiauw Jan Julien M | Laundry treatment compositions with improved odor |
CA2709704C (en) * | 2008-01-04 | 2013-08-06 | The Procter & Gamble Company | A laundry detergent composition comprising glycosyl hydrolase |
US20090209447A1 (en) * | 2008-02-15 | 2009-08-20 | Michelle Meek | Cleaning compositions |
PL2300588T3 (pl) | 2008-06-06 | 2019-07-31 | The Procter & Gamble Company | Kompozycja detergentu zawierająca odmianę z grupy 44 ksyloglukanazy |
CN103467565A (zh) * | 2008-06-17 | 2013-12-25 | 米伦纽姆医药公司 | 硼酸酯化合物及其医药组合物 |
WO2011005913A1 (en) | 2009-07-09 | 2011-01-13 | The Procter & Gamble Company | A catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte |
WO2011005730A1 (en) | 2009-07-09 | 2011-01-13 | The Procter & Gamble Company | A catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte |
US20110166370A1 (en) * | 2010-01-12 | 2011-07-07 | Charles Winston Saunders | Scattered Branched-Chain Fatty Acids And Biological Production Thereof |
US8236748B2 (en) | 2010-03-12 | 2012-08-07 | The Procter & Gamble Company | pH tuneable amido-gellant for use in consumer product compositions |
CA2791251C (en) | 2010-03-12 | 2014-08-12 | The Procter & Gamble Company | Fluid detergent compositions comprising a di-amido gellant, and processes for making |
PT2603514T (pt) | 2010-08-10 | 2018-11-09 | Rempex Pharmaceuticals Inc | Derivados cíclicos de éster de ácido borónico e suas utilizações terapêuticas |
US20120213726A1 (en) | 2011-02-17 | 2012-08-23 | Phillip Richard Green | Bio-based linear alkylphenyl sulfonates |
MX340089B (es) | 2011-02-17 | 2016-06-23 | Procter & Gamble | Composiciones que comprenden mezclas de alquil fenil sulfonatos de c10-c13. |
WO2013016371A1 (en) | 2011-07-25 | 2013-01-31 | The Procter & Gamble Company | Detergents having acceptable color |
US20130303427A1 (en) | 2011-09-13 | 2013-11-14 | Susana Fernandez Prieto | MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS |
WO2013104897A1 (en) * | 2012-01-09 | 2013-07-18 | University of Tromsø | Therapeutic boron-containing compounds |
EP2716644B1 (en) | 2012-10-03 | 2017-04-05 | The Procter and Gamble Company | A stable enzyme stabilizer premix |
US9241947B2 (en) | 2013-01-04 | 2016-01-26 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
AU2014204045B2 (en) | 2013-01-04 | 2018-10-18 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
US20160024440A1 (en) | 2013-03-14 | 2016-01-28 | Novozymes A/S | Enzyme and Inhibitor Containing Water-Soluble Films |
CN105164244B (zh) | 2013-05-03 | 2019-08-20 | 诺维信公司 | 洗涤剂酶的微囊化 |
FI3604316T3 (fi) | 2014-05-05 | 2024-02-29 | Melinta Therapeutics Inc | Boronaattisuolojen synteesi |
WO2015171398A1 (en) | 2014-05-05 | 2015-11-12 | Rempex Pharmaceuticals, Inc. | Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof |
WO2015179308A1 (en) | 2014-05-19 | 2015-11-26 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
TWI746422B (zh) | 2014-05-20 | 2021-11-21 | 美商千禧製藥公司 | 用於癌症治療的方法 |
JP6700203B2 (ja) | 2014-07-01 | 2020-05-27 | レンペックス・ファーマシューティカルズ・インコーポレイテッド | ボロン酸誘導体およびその治療的使用 |
CN106471110A (zh) | 2014-07-03 | 2017-03-01 | 诺维信公司 | 改进的非蛋白酶类酶稳定化 |
WO2016081297A1 (en) | 2014-11-18 | 2016-05-26 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
CN117904083A (zh) | 2014-12-19 | 2024-04-19 | 诺维信公司 | 蛋白酶变体以及对其进行编码的多核苷酸 |
CN107207537B (zh) | 2014-12-19 | 2019-05-31 | 莱姆派克斯制药公司 | 用于生产硼酸衍生物的设备和连续流方法 |
WO2016149393A1 (en) | 2015-03-17 | 2016-09-22 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
WO2017005816A1 (en) | 2015-07-06 | 2017-01-12 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
US10675589B2 (en) | 2015-10-14 | 2020-06-09 | Novozymes A/S | Cleaning of water filtration membranes |
MY196909A (en) | 2016-06-30 | 2023-05-09 | Qpex Biopharma Inc | Boronic acid derivatives and therapeutic uses thereof |
EP3619304A1 (en) | 2017-05-05 | 2020-03-11 | Novozymes A/S | Compositions comprising lipase and sulfite |
US20200181542A1 (en) | 2017-06-30 | 2020-06-11 | Novozymes A/S | Enzyme Slurry Composition |
KR102626967B1 (ko) | 2017-10-11 | 2024-01-18 | 큐펙스 바이오파마 인코포레이티드 | 보론산 유도체 및 이의 합성 |
CN111479919A (zh) | 2017-11-01 | 2020-07-31 | 诺维信公司 | 多肽以及包含此类多肽的组合物 |
US11767492B2 (en) | 2017-11-01 | 2023-09-26 | Novozymes A/S | Methods of treating fabric using a Lactobacillus hexosaminidase |
EP3765185B1 (en) | 2018-03-13 | 2023-07-19 | Novozymes A/S | Microencapsulation using amino sugar oligomers |
CA3097127A1 (en) | 2018-04-20 | 2019-10-24 | Qpex Biopharma, Inc. | Boronic acid derivatives and therapeutic uses thereof |
ES2981999T3 (es) | 2018-10-31 | 2024-10-14 | Henkel Ag & Co Kgaa | Composiciones limpiadoras que contienen dispersinas V |
EP3647397A1 (en) | 2018-10-31 | 2020-05-06 | Henkel AG & Co. KGaA | Cleaning compositions containing dispersins iv |
JP7381740B2 (ja) | 2019-11-27 | 2023-11-15 | ザ プロクター アンド ギャンブル カンパニー | 液体洗濯洗剤組成物 |
WO2021123307A2 (en) | 2019-12-20 | 2021-06-24 | Novozymes A/S | Polypeptides having proteolytic activity and use thereof |
EP4305146A1 (en) | 2021-03-12 | 2024-01-17 | Novozymes A/S | Polypeptide variants |
WO2024131880A2 (en) | 2022-12-23 | 2024-06-27 | Novozymes A/S | Detergent composition comprising catalase and amylase |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2872479A (en) * | 1955-06-30 | 1959-02-03 | Callery Chemical Co | Preparation of organoboron compounds |
US3912595A (en) * | 1974-02-25 | 1975-10-14 | Us Health | Method of purifying enzymes using boronic acids covalently bonded to an insoluble support |
IT1129814B (it) * | 1980-07-02 | 1986-06-11 | Unilever Nv | Composizione detergente enzimatica liquida |
US4462922A (en) * | 1981-11-19 | 1984-07-31 | Lever Brothers Company | Enzymatic liquid detergent composition |
GB8311314D0 (en) * | 1983-04-26 | 1983-06-02 | Unilever Plc | Aqueous enzyme-containing compositions |
US4652394A (en) * | 1983-05-31 | 1987-03-24 | Colgate Palmolive Co. | Built single phase liquid anionic detergent compositions containing stabilized enzymes |
DE3413571A1 (de) * | 1984-04-11 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verwendung von kristallinen schichtfoermigen natriumsilikaten zur wasserenthaertung und verfahren zur wasserenthaertung |
US4537707A (en) * | 1984-05-14 | 1985-08-27 | The Procter & Gamble Company | Liquid detergents containing boric acid and formate to stabilize enzymes |
US4566985A (en) * | 1984-09-19 | 1986-01-28 | Applied Biochemists, Inc. | Method of cleaning using liquid compositions comprising stabilized mixtures of enzymes |
US4747977A (en) * | 1984-11-09 | 1988-05-31 | The Procter & Gamble Company | Ethanol-free liquid laundry detergent compositions |
US4842769A (en) * | 1985-07-26 | 1989-06-27 | Colgate-Palmolive Co. | Stabilized fabric softening built detergent composition containing enzymes |
US4900475A (en) * | 1985-07-26 | 1990-02-13 | Colgate-Palmolive Co. | Stabilized built liquid detergent composition containing enzyme |
WO1987000859A1 (en) * | 1985-08-09 | 1987-02-12 | Gist-Brocades N.V. | Novel lipolytic enzymes and their use in detergent compositions |
EG18543A (en) * | 1986-02-20 | 1993-07-30 | Albright & Wilson | Protected enzyme systems |
US4842758A (en) * | 1986-10-31 | 1989-06-27 | Colgate-Palmolive Company | Stabilized enzyme system for use in aqueous liquid built detergent compositions |
US4704233A (en) * | 1986-11-10 | 1987-11-03 | The Procter & Gamble Company | Detergent compositions containing ethylenediamine-N,N'-disuccinic acid |
US5187157A (en) * | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
DK571587D0 (da) * | 1987-11-02 | 1987-11-02 | Novo Industri As | Enzymatisk detergentsammensaetning |
EP0315574A3 (de) * | 1987-11-05 | 1990-08-22 | Hoechst Aktiengesellschaft | Renin-Inhibitoren |
GB8810822D0 (en) * | 1988-05-06 | 1988-06-08 | Unilever Plc | Liquid detergent compositions |
US4963655A (en) * | 1988-05-27 | 1990-10-16 | Mayo Foundation For Medical Education And Research | Boron analogs of amino acid/peptide protease inhibitors |
US5039446A (en) * | 1988-07-01 | 1991-08-13 | Genencor International, Inc. | Liquid detergent with stabilized enzyme |
DE3840452A1 (de) * | 1988-12-01 | 1990-06-07 | Hoechst Ag | (beta)-amino-boronsaeure-derivate |
CA2006527A1 (en) * | 1988-12-30 | 1990-06-30 | Martin S. Cardinali | Enzymatic liquid detergent compositions |
US4959179A (en) * | 1989-01-30 | 1990-09-25 | Lever Brothers Company | Stabilized enzymes liquid detergent composition containing lipase and protease |
US4908150A (en) * | 1989-02-02 | 1990-03-13 | Lever Brothers Company | Stabilized lipolytic enzyme-containing liquid detergent composition |
EP0385401A1 (en) * | 1989-02-27 | 1990-09-05 | Occidental Chemical Corporation | Unique Microbial lipases with activity at temperatures and pHs suitable for use in detergents |
ES2141080T3 (es) * | 1989-05-15 | 2000-03-16 | Clorox Co | Procedimiento para el lavado de tejidos. |
EP0450702A3 (en) * | 1990-04-06 | 1993-06-02 | Unilever N.V. | Process for preparing liquid enzymatic detergent compositions |
EP0478050A1 (en) * | 1990-09-24 | 1992-04-01 | Unilever N.V. | Detergent composition |
DE69121059T2 (de) * | 1990-11-14 | 1997-03-06 | The Procter & Gamble Co., Cincinnati, Ohio | Lipase- und proteasehaltige flüssige Waschmittelzusammensetzung |
-
1992
- 1992-08-14 US US07/931,809 patent/US5442100A/en not_active Expired - Fee Related
-
1993
- 1993-08-03 JP JP6506312A patent/JPH08500113A/ja active Pending
- 1993-08-03 WO PCT/US1993/007276 patent/WO1994004542A1/en active IP Right Grant
- 1993-08-03 EP EP93918597A patent/EP0655067B1/en not_active Expired - Lifetime
- 1993-08-03 DE DE69315079T patent/DE69315079T2/de not_active Expired - Fee Related
- 1993-08-03 AU AU47997/93A patent/AU4799793A/en not_active Abandoned
- 1993-08-03 AT AT93918597T patent/ATE159945T1/de not_active IP Right Cessation
- 1993-08-14 CN CN93117839A patent/CN1047596C/zh not_active Expired - Fee Related
- 1993-08-16 MX MX9304970A patent/MX9304970A/es not_active IP Right Cessation
- 1993-10-13 TW TW082108452A patent/TW251274B/zh active
-
1995
- 1995-05-04 US US08/434,901 patent/US5488157A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
MX9304970A (es) | 1994-05-31 |
EP0655067A1 (en) | 1995-05-31 |
CN1090850A (zh) | 1994-08-17 |
US5442100A (en) | 1995-08-15 |
JPH08500113A (ja) | 1996-01-09 |
DE69315079D1 (de) | 1997-12-11 |
CN1047596C (zh) | 1999-12-22 |
DE69315079T2 (de) | 1998-06-04 |
ATE159945T1 (de) | 1997-11-15 |
US5488157A (en) | 1996-01-30 |
EP0655067B1 (en) | 1997-11-05 |
WO1994004542A1 (en) | 1994-03-03 |
AU4799793A (en) | 1994-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW251274B (zh) | ||
AU8088694A (en) | 2'-amido and 2'-peptido modified oligonucleotides | |
MY137301A (en) | Peptide analogs as irreversible interleukin-1b protease inhibitors | |
TW329423B (en) | Compounds containing a fused bicyclic ring and processes therefor | |
CZ85395A3 (en) | Derivatives of vaprooic and 1-valproenic acids and pharmaceutical preparations based thereon | |
AU5211393A (en) | Sustained-released preparation | |
TW334418B (en) | Stilbene derivatives and pharmaceutical compositions | |
NZ335157A (en) | N-(aryl/heteroaryl) amino acid derivatives and methods for inhibiting beta-amyloid peptide release or its synthesis | |
IE801342L (en) | Peptides | |
TW232009B (zh) | ||
IL124507A (en) | Oligopeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone | |
IE890175L (en) | Aminoacid glycerides. | |
MX9605737A (es) | Transfeccion de celulas. | |
AU7993587A (en) | The synthesis of peptide aminoalkylamides and peptide hydrazides by the solid-phase method | |
AU8223991A (en) | New salts derived from dialkylaminoalkylsulphonyl-26 pristinamycin iib | |
TW324719B (en) | Succinamide compound, production thereof and use thereof | |
ES2004804A6 (es) | Un procedimiento para preparar derivados de carboxialquildipeptidos | |
ES557260A1 (es) | Procedimiento para la obtencion de azacicloalcanos y azacicloalquenos 1,3,4-trisustituidos | |
TH14443A (th) | (สูตร) - อะมิโนแอลคิลและ (สูตร)-n- เพปทิดิลอะมิโนแอลคิลปอโรนิคแอซิด | |
GEP19970937B (en) | Method of producing derivatives of muramyldipeptide | |
MX9710225A (es) | Inhibidores calpaina para el tratamiento de enfermedades neurodegenerativas. | |
MX9706187A (es) | Derivados de 3-pirrolidiliden-2-ona-cefalosporinas. |