TR200103708T2 - Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplant - Google Patents
Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplantInfo
- Publication number
- TR200103708T2 TR200103708T2 TR2001/03708T TR200103708T TR200103708T2 TR 200103708 T2 TR200103708 T2 TR 200103708T2 TR 2001/03708 T TR2001/03708 T TR 2001/03708T TR 200103708 T TR200103708 T TR 200103708T TR 200103708 T2 TR200103708 T2 TR 200103708T2
- Authority
- TR
- Turkey
- Prior art keywords
- mct
- membrane
- glutamicum
- nucleic acid
- acid molecules
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 102000000562 Monocarboxylic Acid Transporters Human genes 0.000 abstract 3
- 108010041817 Monocarboxylic Acid Transporters Proteins 0.000 abstract 3
- 241000186226 Corynebacterium glutamicum Species 0.000 abstract 2
- -1 MCT nucleic acid Chemical class 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Corynebacterium glutamicum'dan türetilmis yeni MCT proteinlerini sifreleyen MCT nükleik asit molekülleri adli izole edilmis nükleik asit molekülleri tarif edilmektedir. Bulus anti duyarli nükleik asit molekülleri, MCT nükleik asit molekülleri ihtiva eden yeniden birlestirici tanim vektörleri ve tanim vektörlerinin yerlestirildigi konakçi hücreler de saglar. Hali hazirda bulus ayrica izole edilmis MCT proteinleri, mutasyon geçirmis MCT proteinleri, füzyon proteinleri, antijenik peptidler ve bu organizmadaki MCT genlerinin genetik mühendisligine dayanarak arzu edilen bir bilesigin C.Glutamicum'dan üretiminin gelistirlmesine yönelik metotlar saglar.MCT nucleic acid molecules encoding new MCT proteins derived from Corynebacterium glutamicum, forensic isolated nucleic acid molecules are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCT nucleic acid molecules, and host cells in which expression vectors are located. Based on the genetic engineering of MCT proteins, mutated MCT proteins, fusion proteins, antigenic peptides and MCT genes in the present invention, it also provides methods for developing the production of a desired compound from C. Glutamicum.
Applications Claiming Priority (35)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14103199P | 1999-06-25 | 1999-06-25 | |
DE19931563 | 1999-07-08 | ||
DE19931478 | 1999-07-08 | ||
DE19931454 | 1999-07-08 | ||
DE19932228 | 1999-07-09 | ||
DE19932124 | 1999-07-09 | ||
DE19932180 | 1999-07-09 | ||
DE19932209 | 1999-07-09 | ||
DE19932212 | 1999-07-09 | ||
DE19932190 | 1999-07-09 | ||
DE19932182 | 1999-07-09 | ||
DE19932125 | 1999-07-09 | ||
DE19932191 | 1999-07-09 | ||
DE19932227 | 1999-07-09 | ||
DE19932122 | 1999-07-09 | ||
DE19932230 | 1999-07-09 | ||
DE19932229 | 1999-07-09 | ||
DE19932128 | 1999-07-09 | ||
DE19933005 | 1999-07-14 | ||
DE19933006 | 1999-07-14 | ||
DE19932927 | 1999-07-14 | ||
DE19940764 | 1999-08-27 | ||
DE19940830 | 1999-08-27 | ||
DE19940832 | 1999-08-27 | ||
DE19940833 | 1999-08-27 | ||
DE19940765 | 1999-08-27 | ||
DE19940831 | 1999-08-27 | ||
DE19940766 | 1999-08-27 | ||
DE19941395 | 1999-08-31 | ||
DE19941379 | 1999-08-31 | ||
DE19941378 | 1999-08-31 | ||
DE19942078 | 1999-09-03 | ||
DE19942079 | 1999-09-03 | ||
DE19942088 | 1999-09-03 | ||
DE19942077 | 1999-09-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200103708T2 true TR200103708T2 (en) | 2002-08-21 |
Family
ID=27586932
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/07441T TR200607441T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
TR2006/07443T TR200607443T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation |
TR2001/03708T TR200103708T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplant |
TR2006/07442T TR200607442T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/07441T TR200607441T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
TR2006/07443T TR200607443T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/07442T TR200607442T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1255839A2 (en) |
JP (2) | JP2004513603A (en) |
KR (3) | KR20070087032A (en) |
CA (1) | CA2380863A1 (en) |
CZ (1) | CZ20014660A3 (en) |
ES (1) | ES2177476T1 (en) |
MX (1) | MXPA01012845A (en) |
SK (1) | SK18912001A3 (en) |
TR (4) | TR200607441T2 (en) |
WO (1) | WO2001000805A2 (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0012020A (en) | 1999-07-02 | 2002-07-02 | Ajinomoto Kk | Protein, and DNA |
DE19941478A1 (en) * | 1999-09-01 | 2001-03-08 | Degussa | New nucleotide sequences coding for the thrE gene and process for the fermentative production of L-threonine with coryneform bacteria |
DE10021828A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the cdsA gene |
DE10021832A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the cma gene |
US6562607B2 (en) | 2000-05-04 | 2003-05-13 | Degussa-Huls Aktiengesellschaft | Nucleotide sequences coding for the cls gene |
DE10021829A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the pgsA2 gene |
DE10021831A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the fadD15 gene |
DE10021826A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the cls gene |
DE10023400A1 (en) | 2000-05-12 | 2001-11-15 | Degussa | New acyl-carrier protein gene, acp, from coryneform bacteria, useful for increasing fermentative production of amino acids, especially lysine |
US20020081673A1 (en) * | 2000-06-02 | 2002-06-27 | Bettina Mockel | Novel nucleotide sequences coding for the glbO gene |
DE10032173A1 (en) * | 2000-07-01 | 2002-01-17 | Degussa | New nucleotide sequences encoding the plsC gene |
DE10045579A1 (en) * | 2000-09-15 | 2002-04-11 | Degussa | New nucleotide sequences coding for the atr61 gene |
WO2002024915A1 (en) * | 2000-09-19 | 2002-03-28 | Degussa Ag | Dcta (c4-dicarboxylate transporter) from corynebacterium glutamicum |
DE10057801A1 (en) * | 2000-11-22 | 2002-05-23 | Degussa | New polynucleotide encoding the CysQ transporter of coryneform bacteria, useful, when over expressed, for increasing fermentative production of amino acids |
DE10154179A1 (en) * | 2001-11-05 | 2003-05-08 | Basf Ag | Genes coding for membrane synthesis and membrane transport proteins |
DE10154270A1 (en) | 2001-11-05 | 2003-05-15 | Basf Ag | Genes that code for carbon metabolism and energy production proteins |
DE10163167A1 (en) * | 2001-12-21 | 2003-07-03 | Degussa | Process for the fermentative production of L-amino acids and use of coryneform bacteria |
JP4331103B2 (en) * | 2002-05-14 | 2009-09-16 | マーテック・バイオサイエンシーズ・コーポレーション | Carotene synthase gene and uses thereof |
US7468262B2 (en) | 2003-05-16 | 2008-12-23 | Ajinomoto Co., Inc. | Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum |
DE102004009454A1 (en) * | 2004-02-27 | 2005-09-15 | Degussa Ag | Fermentative production of L-amino acids, especially methionine, useful e.g. in animal nutrition, by culturing bacteria in which components of the methionine uptake system are suppressed |
JP5493854B2 (en) * | 2007-04-10 | 2014-05-14 | 味の素株式会社 | Method for producing organic acid |
KR101694850B1 (en) * | 2014-10-08 | 2017-01-10 | 씨제이제일제당 주식회사 | Microorganism producing L-glutamine and process for preparing L-glutamine using the same |
JP7156594B2 (en) * | 2017-04-04 | 2022-10-19 | エヌエヌビー ニュートリション ユーエスエー、エルエルシー | Preparation of (R)-3-hydroxybutyric acid or its salts by one-step fermentation |
KR101968317B1 (en) * | 2018-02-23 | 2019-04-11 | 씨제이제일제당 주식회사 | Novel L-tryptophan export protein and the method of producing L-tryptophan usingthe same |
WO2019228937A1 (en) * | 2018-05-28 | 2019-12-05 | Universitaet Des Saarlandes | Means and methods for the production of glutarate |
EP3670525A1 (en) | 2018-12-18 | 2020-06-24 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains with a mutated kup transporter |
CN112143676B (en) * | 2020-09-21 | 2022-03-18 | 山西大学 | Bacillus halodurans for producing alkaline protease and method and application of bacillus halodurans for producing alkaline protease |
CN112646766B (en) * | 2020-12-30 | 2023-08-18 | 内蒙古伊品生物科技有限公司 | Recombinant strain for producing L-glutamic acid by modifying gene BBD29_04920 as well as construction method and application thereof |
CN114763372B (en) * | 2021-01-13 | 2024-12-10 | 中国科学院天津工业生物技术研究所 | Protein with L-proline efflux function and its application |
KR102261851B1 (en) * | 2021-01-15 | 2021-06-04 | 씨제이제일제당 (주) | Novel ABC transporter ATP-binding protein variant and a method for producing L-lysine using the same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1196453B (en) * | 1986-07-04 | 1988-11-16 | Sclavo Spa | CORYNEBACTERIUM DIPHTHERIAE DNA ELEMENT WITH TYPICAL PROPERTIES OF AN IS INSERTION ELEMENT |
US6649379B1 (en) * | 1987-06-12 | 2003-11-18 | Massachusetts Institute Of Technology | Method and deregulated enzyme for threonine production |
JP2967996B2 (en) * | 1989-06-06 | 1999-10-25 | 協和醗酵工業株式会社 | Method for producing L-tryptophan |
MY113040A (en) * | 1994-02-24 | 2001-11-30 | Ajinomoto Kk | Novel gene derived from coryneform bacteria and use thereof |
US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
-
2000
- 2000-06-23 KR KR1020077015871A patent/KR20070087032A/en not_active Withdrawn
- 2000-06-23 CA CA002380863A patent/CA2380863A1/en not_active Abandoned
- 2000-06-23 TR TR2006/07441T patent/TR200607441T2/en unknown
- 2000-06-23 KR KR1020067022650A patent/KR100878332B1/en not_active Expired - Fee Related
- 2000-06-23 TR TR2006/07443T patent/TR200607443T2/en unknown
- 2000-06-23 TR TR2001/03708T patent/TR200103708T2/en unknown
- 2000-06-23 JP JP2001506799A patent/JP2004513603A/en active Pending
- 2000-06-23 SK SK1891-2001A patent/SK18912001A3/en not_active Application Discontinuation
- 2000-06-23 MX MXPA01012845A patent/MXPA01012845A/en not_active Application Discontinuation
- 2000-06-23 EP EP00939001A patent/EP1255839A2/en not_active Ceased
- 2000-06-23 CZ CZ20014660A patent/CZ20014660A3/en unknown
- 2000-06-23 TR TR2006/07442T patent/TR200607442T2/en unknown
- 2000-06-23 WO PCT/IB2000/000926 patent/WO2001000805A2/en active Application Filing
- 2000-06-23 ES ES00939001T patent/ES2177476T1/en active Pending
- 2000-06-23 KR KR1020017016590A patent/KR100834989B1/en not_active Expired - Fee Related
-
2006
- 2006-05-11 JP JP2006132306A patent/JP2006271389A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2380863A1 (en) | 2001-01-04 |
TR200607443T2 (en) | 2007-10-22 |
ES2177476T1 (en) | 2002-12-16 |
WO2001000805A3 (en) | 2001-10-25 |
KR100834989B1 (en) | 2008-06-03 |
TR200607441T2 (en) | 2007-02-21 |
JP2004513603A (en) | 2004-05-13 |
MXPA01012845A (en) | 2002-07-09 |
CZ20014660A3 (en) | 2002-09-11 |
KR20030002295A (en) | 2003-01-08 |
EP1255839A2 (en) | 2002-11-13 |
KR20070087032A (en) | 2007-08-27 |
TR200607443T1 (en) | 2007-04-24 |
SK18912001A3 (en) | 2002-10-08 |
WO2001000805A2 (en) | 2001-01-04 |
TR200607442T2 (en) | 2007-02-21 |
KR100878332B1 (en) | 2009-01-14 |
KR20060118626A (en) | 2006-11-23 |
JP2006271389A (en) | 2006-10-12 |
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