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TNSN88010A1 - Procede de preparation de derives d'azepinone et d'azocinone condenses. - Google Patents

Procede de preparation de derives d'azepinone et d'azocinone condenses.

Info

Publication number
TNSN88010A1
TNSN88010A1 TNTNSN88010A TNSN88010A TNSN88010A1 TN SN88010 A1 TNSN88010 A1 TN SN88010A1 TN TNSN88010 A TNTNSN88010 A TN TNSN88010A TN SN88010 A TNSN88010 A TN SN88010A TN SN88010 A1 TNSN88010 A1 TN SN88010A1
Authority
TN
Tunisia
Prior art keywords
group
hydrogen atom
azocinone
azepinone
condensed
Prior art date
Application number
TNTNSN88010A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of TNSN88010A1 publication Critical patent/TNSN88010A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

DANS LAQUELLE M = 1 OU 2 ET N = 0, 1 OU 2 ; R1 ET R2 REPRESENTENT DES RADICAUX IDENTIQUES OU DIFFERENTS, CHOISIS PARMI UN ATOME D'HYDROGENE, UN GROUPE ALKYLE EVENTUELLEMENT SUBSTITUE, ALCENYLE, CYCLOALKYLE, CYCLOALCENYLE, CYCLOALKYLALKYLE, UN GROUPE ARYLE PARTIELLEMENT HYDROGENE ET UN GROUPE ARALKYLE EVENTUELLEMENT SUBSTITUE ; R3 ET R4 REPRESENTENT DES RADICAUX IDENTIQUES OU DIFFERENTS, CHOISIS PARMI UN ATOME D'HYDROGENE, UN GROUPE ALKYLE, ALCENYLE ET UN RADICAL ARALKYLE EVENTUELLEMENT SUBSTITUE ; Y REPRESENTE UN ATOME D'HYDROGENE OU LE GROUPE HYDROXY ; Z REPRESENTE UN ATOME D'HYDROGENE, OU Y ET Z REPRESENTENT ENSEMBLE UN GROUPE OXO ; ET X REPRESENTE UN GROUPE ALKYLE EVENTUELLEMENT SUBSTITUE, ALCENYLE, CYCLOALKYLE, 4-PIPERIDINYLE EVENTUELLEMENT SUBSTITUE, ARYLE EVENTUELLEMENT SUBSTITUE OU INDOLYLE.
TNTNSN88010A 1987-02-14 1988-02-12 Procede de preparation de derives d'azepinone et d'azocinone condenses. TNSN88010A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873704661 DE3704661A1 (de) 1987-02-14 1987-02-14 Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Publications (1)

Publication Number Publication Date
TNSN88010A1 true TNSN88010A1 (fr) 1990-07-10

Family

ID=6320980

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN88010A TNSN88010A1 (fr) 1987-02-14 1988-02-12 Procede de preparation de derives d'azepinone et d'azocinone condenses.

Country Status (26)

Country Link
US (1) US4857520A (fr)
EP (1) EP0279350B1 (fr)
JP (1) JP2638034B2 (fr)
KR (1) KR960011376B1 (fr)
AR (1) AR246957A1 (fr)
AT (1) ATE97913T1 (fr)
AU (1) AU610124B2 (fr)
CA (1) CA1313371C (fr)
CZ (1) CZ280148B6 (fr)
DD (1) DD279877A5 (fr)
DE (2) DE3704661A1 (fr)
DK (1) DK172553B1 (fr)
ES (1) ES2061531T3 (fr)
FI (1) FI86849C (fr)
HU (2) HU208425B (fr)
IE (1) IE62354B1 (fr)
IL (1) IL85406A (fr)
JO (1) JO1524B1 (fr)
MA (1) MA21181A1 (fr)
MX (1) MX174166B (fr)
NO (1) NO176763C (fr)
NZ (1) NZ223500A (fr)
PH (1) PH25186A (fr)
PT (1) PT86748B (fr)
TN (1) TNSN88010A1 (fr)
ZA (1) ZA88991B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
US5587375A (en) * 1995-02-17 1996-12-24 Bristol-Myers Squibb Company Azepinone compounds useful in the inhibition of ACE and NEP
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
ME00429B (fr) * 1999-08-30 2011-10-10 Aventis Pharma Deutschland Gmbh Utilisation d'inhibiteurs du systeme renine-angiotensine dans la prevention de manifestations cardio-vasculaires

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354146A (en) * 1967-11-21 Process for the production of cyclo- pentano omega-oenantholactam
US4141893A (en) * 1976-11-02 1979-02-27 Eli Lilly And Company Decahydrocyclopent[c]azepines
DE3269625D1 (en) * 1981-08-11 1986-04-10 Ciba Geigy Ag Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use
DE3373469D1 (en) * 1982-09-30 1987-10-15 Merck & Co Inc 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
DE3426720A1 (de) * 1984-07-20 1986-01-23 Hoechst Ag, 6230 Frankfurt Benzthiazepinon- und benzthiazocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Also Published As

Publication number Publication date
AU610124B2 (en) 1991-05-16
ZA88991B (en) 1988-08-10
HUT50785A (en) 1990-03-28
CA1313371C (fr) 1993-02-02
IL85406A (en) 1992-06-21
HUT48602A (en) 1989-06-28
ATE97913T1 (de) 1993-12-15
DK172553B1 (da) 1999-01-11
JP2638034B2 (ja) 1997-08-06
IE62354B1 (en) 1995-01-25
MX10408A (es) 1993-07-01
FI880632A0 (fi) 1988-02-11
HU203727B (en) 1991-09-30
AU1167288A (en) 1988-08-18
JO1524B1 (en) 1989-01-25
PT86748B (pt) 1992-04-30
EP0279350B1 (fr) 1993-12-01
IL85406A0 (en) 1988-07-31
KR960011376B1 (ko) 1996-08-22
NO176763C (no) 1995-05-24
DK72488A (da) 1988-08-15
ES2061531T3 (es) 1994-12-16
DD279877A5 (de) 1990-06-20
NO880628D0 (no) 1988-02-12
FI86849C (fi) 1992-10-26
NZ223500A (en) 1990-11-27
NO176763B (no) 1995-02-13
FI880632A (fi) 1988-08-15
IE880390L (en) 1988-08-14
NO880628L (no) 1988-08-15
DE3885914D1 (de) 1994-01-13
AR246957A1 (es) 1994-10-31
MX174166B (es) 1994-04-26
US4857520A (en) 1989-08-15
EP0279350A2 (fr) 1988-08-24
DE3704661A1 (de) 1988-08-25
EP0279350A3 (en) 1990-09-05
CZ280148B6 (cs) 1995-11-15
PH25186A (en) 1991-03-27
KR880009939A (ko) 1988-10-06
FI86849B (fi) 1992-07-15
DK72488D0 (da) 1988-02-12
CZ89288A3 (en) 1994-12-15
MA21181A1 (fr) 1988-10-01
PT86748A (pt) 1988-03-01
HU208425B (en) 1993-10-28
JPS63203665A (ja) 1988-08-23

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