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SMT201600131B - Procedimento per la produzione di piastrine - Google Patents

Procedimento per la produzione di piastrine

Info

Publication number
SMT201600131B
SMT201600131B SM201600131T SM201600131T SMT201600131B SM T201600131 B SMT201600131 B SM T201600131B SM 201600131 T SM201600131 T SM 201600131T SM 201600131 T SM201600131 T SM 201600131T SM T201600131 B SMT201600131 B SM T201600131B
Authority
SM
San Marino
Prior art keywords
procedure
plates
production
Prior art date
Application number
SM201600131T
Other languages
English (en)
Inventor
Dominique Baruch
Elisabeth Cramer-Borde
Claire Dunois-Larde
Original Assignee
Inst Nat Sante Rech Med
Assist Publ Hopitaux De Paris
Univ Paris Descartes
Univ Versailles Saint Quentin En Yvelines L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Assist Publ Hopitaux De Paris, Univ Paris Descartes, Univ Versailles Saint Quentin En Yvelines L filed Critical Inst Nat Sante Rech Med
Publication of SMT201600131B publication Critical patent/SMT201600131B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0644Platelets; Megakaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/125Stem cell factor [SCF], c-kit ligand [KL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/145Thrombopoietin [TPO]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
SM201600131T 2008-12-04 2016-05-04 Procedimento per la produzione di piastrine SMT201600131B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08305881 2008-12-04
PCT/EP2009/066401 WO2010063823A1 (en) 2008-12-04 2009-12-04 Method for producing platelets
EP09768362.7A EP2352815B1 (en) 2008-12-04 2009-12-04 Method for producing platelets

Publications (1)

Publication Number Publication Date
SMT201600131B true SMT201600131B (it) 2016-07-01

Family

ID=40756593

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600131T SMT201600131B (it) 2008-12-04 2016-05-04 Procedimento per la produzione di piastrine

Country Status (17)

Country Link
US (1) US9012221B2 (it)
EP (1) EP2352815B1 (it)
JP (1) JP5863459B2 (it)
CN (2) CN104087552A (it)
AU (1) AU2009324042B2 (it)
BR (1) BRPI0922710A8 (it)
CA (1) CA2745268C (it)
CY (1) CY1117452T1 (it)
DK (1) DK2352815T3 (it)
ES (1) ES2569610T3 (it)
HK (1) HK1165491A1 (it)
HR (1) HRP20160404T8 (it)
HU (1) HUE027112T2 (it)
PL (1) PL2352815T3 (it)
SI (1) SI2352815T1 (it)
SM (1) SMT201600131B (it)
WO (1) WO2010063823A1 (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012129109A2 (en) * 2011-03-18 2012-09-27 New York Blood Center, Inc. Megakaryocyte and platelet production from stem cells
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
CA2896053A1 (en) 2012-12-21 2014-06-26 Ocata Therapeutics, Inc. Methods for production of platelets from pluripotent stem cells and compositions thereof
EP2941642B1 (en) * 2013-01-03 2020-05-13 Brigham and Women's Hospital, Inc. System and method for a biomimetic fluid processing
EP3071327A1 (en) 2013-11-19 2016-09-28 Platod Fluidic device for producing platelets
JP2015181406A (ja) * 2014-03-24 2015-10-22 東レエンジニアリング株式会社 血小板産生装置および血小板産生方法
CA2944314C (en) * 2014-03-31 2023-09-19 Brigham And Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
US10538738B2 (en) * 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
WO2016180918A1 (en) 2015-05-12 2016-11-17 Platod Combination of pharmacological and microfluidic features for improved platelets production
ES2839220T3 (es) * 2015-06-16 2021-07-05 Univ Kyoto Procedimiento de fabricación de plaquetas de alto rendimiento
EP3347029B1 (en) * 2015-09-08 2022-03-09 Brigham and Women's Hospital, Inc. System and method for producing blood platelets
EP3351627A4 (en) 2015-09-15 2019-03-27 Megakaryon Corporation PROCESS FOR THE PRODUCTION OF BLOOD PLATES ON THE BASIS OF A ROTATING STIRRING CULTURING METHOD
CN108135940B (zh) * 2015-10-14 2022-04-15 株式会社美加细胞 纯化血小板的制造方法
SG11201803591UA (en) * 2015-11-02 2018-05-30 Megakaryon Corp Method for producing platelets using reciprocating stirring device
US20200123487A1 (en) * 2017-06-20 2020-04-23 Northwestern University Microfluidic platelet bioreactor device and systems
MX2020007071A (es) 2018-01-05 2020-11-11 Platelet Biogenesis Inc Composiciones y metodos para producir megacariocitos.
FR3101885A1 (fr) * 2019-10-11 2021-04-16 Etablissement Français Du Sang Systeme pour la liberation de plaquettes et procede de liberation de plaquettes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344560A (en) * 1979-11-02 1982-08-17 Asahi Kasei Kogyo Kabushiki Kaisha Container, apparatus and method for separating platelets
DE19956156A1 (de) * 1999-11-23 2001-06-13 Univ Eberhard Karls Verfahren zur Aufbereitung eines Präparates von Thrombozyten und Thrombozytenpräparat
EP1369128A1 (en) * 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
JP2008518603A (ja) * 2004-11-01 2008-06-05 ウイスコンシン アラムニ リサーチ ファンデーション 幹細胞由来の血小板
PT1836500E (pt) * 2005-01-14 2010-09-28 Ablynx Nv Métodos e ensaios para distinguir diferentes formas de doenças e perturbações caracterizadas por trombocitopenia e/ou por interacção espontânea entre o factor de von willebrand (vwf) e plaquetas
JP5419076B2 (ja) * 2008-05-15 2014-02-19 旭化成メディカル株式会社 血小板の誘導方法

Also Published As

Publication number Publication date
US9012221B2 (en) 2015-04-21
PL2352815T3 (pl) 2016-07-29
CN102300984B (zh) 2014-06-04
DK2352815T3 (en) 2016-05-17
HK1165491A1 (en) 2012-10-05
HRP20160404T1 (hr) 2016-06-17
HUE027112T2 (en) 2016-08-29
BRPI0922710A8 (pt) 2018-06-26
BRPI0922710A2 (pt) 2016-01-05
ES2569610T3 (es) 2016-05-11
CA2745268C (en) 2018-11-13
AU2009324042A1 (en) 2011-07-07
HRP20160404T8 (hr) 2016-07-01
JP5863459B2 (ja) 2016-02-16
WO2010063823A1 (en) 2010-06-10
AU2009324042B2 (en) 2014-12-04
SI2352815T1 (sl) 2016-10-28
EP2352815A1 (en) 2011-08-10
CN104087552A (zh) 2014-10-08
US20120014933A1 (en) 2012-01-19
JP2012510804A (ja) 2012-05-17
EP2352815B1 (en) 2016-02-10
CY1117452T1 (el) 2017-04-26
CA2745268A1 (en) 2010-06-10
CN102300984A (zh) 2011-12-28

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