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SK5452003A3 - Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders - Google Patents

Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders Download PDF

Info

Publication number
SK5452003A3
SK5452003A3 SK545-2003A SK5452003A SK5452003A3 SK 5452003 A3 SK5452003 A3 SK 5452003A3 SK 5452003 A SK5452003 A SK 5452003A SK 5452003 A3 SK5452003 A3 SK 5452003A3
Authority
SK
Slovakia
Prior art keywords
cancer
pentamidine
chlorpromazine
drug
group
Prior art date
Application number
SK545-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Alexis Borisy
Curtis Keith
Michael A Foley
Brent R Stockwell
Original Assignee
Combinatorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx Inc filed Critical Combinatorx Inc
Publication of SK5452003A3 publication Critical patent/SK5452003A3/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SK545-2003A 2000-11-06 2001-10-30 Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders SK5452003A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/706,929 US6569853B1 (en) 2000-11-06 2000-11-06 Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders
PCT/US2001/047959 WO2002058684A2 (en) 2000-11-06 2001-10-30 Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders

Publications (1)

Publication Number Publication Date
SK5452003A3 true SK5452003A3 (en) 2004-07-07

Family

ID=24839666

Family Applications (1)

Application Number Title Priority Date Filing Date
SK545-2003A SK5452003A3 (en) 2000-11-06 2001-10-30 Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders

Country Status (29)

Country Link
US (4) US6569853B1 (pt)
EP (1) EP1339399B1 (pt)
JP (1) JP2004517915A (pt)
KR (1) KR100720205B1 (pt)
CN (1) CN1484525A (pt)
AR (1) AR035500A1 (pt)
AT (1) ATE318590T1 (pt)
AU (1) AU2002246636B8 (pt)
BG (1) BG107831A (pt)
BR (1) BR0115166A (pt)
CA (1) CA2436799C (pt)
CY (1) CY1105501T1 (pt)
DE (1) DE60117615T2 (pt)
DK (1) DK1339399T3 (pt)
EE (1) EE200300212A (pt)
ES (1) ES2258566T3 (pt)
HR (1) HRP20030460A2 (pt)
HU (1) HUP0400529A3 (pt)
IL (1) IL155795A0 (pt)
IS (1) IS2457B (pt)
MX (1) MXPA03003960A (pt)
NO (1) NO20032036L (pt)
NZ (1) NZ525773A (pt)
PL (1) PL362690A1 (pt)
PT (1) PT1339399E (pt)
RU (1) RU2286769C2 (pt)
SK (1) SK5452003A3 (pt)
TW (1) TWI259077B (pt)
WO (1) WO2002058684A2 (pt)

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Also Published As

Publication number Publication date
DK1339399T3 (da) 2006-06-19
EP1339399A2 (en) 2003-09-03
HUP0400529A3 (en) 2006-02-28
BR0115166A (pt) 2003-12-30
JP2004517915A (ja) 2004-06-17
NZ525773A (en) 2005-04-29
AU2002246636B8 (en) 2006-01-19
US6846816B2 (en) 2005-01-25
WO2002058684A3 (en) 2003-04-17
US20050192274A1 (en) 2005-09-01
CA2436799C (en) 2007-12-18
DE60117615D1 (de) 2006-04-27
EP1339399B1 (en) 2006-03-01
BG107831A (bg) 2004-02-27
IS2457B (is) 2008-11-15
US20030166642A1 (en) 2003-09-04
CY1105501T1 (el) 2010-04-28
TWI259077B (en) 2006-08-01
US20070099906A1 (en) 2007-05-03
CA2436799A1 (en) 2002-08-01
NO20032036L (no) 2003-07-04
PL362690A1 (en) 2004-11-02
MXPA03003960A (es) 2004-09-10
US6569853B1 (en) 2003-05-27
US7148216B2 (en) 2006-12-12
AU2002246636B2 (en) 2005-12-01
HRP20030460A2 (en) 2005-04-30
ES2258566T3 (es) 2006-09-01
KR100720205B1 (ko) 2007-05-21
PT1339399E (pt) 2006-07-31
KR20030048460A (ko) 2003-06-19
CN1484525A (zh) 2004-03-24
ATE318590T1 (de) 2006-03-15
WO2002058684A2 (en) 2002-08-01
NO20032036D0 (no) 2003-05-06
AR035500A1 (es) 2004-06-02
DE60117615T2 (de) 2006-11-09
IS6806A (is) 2003-05-05
IL155795A0 (en) 2003-12-23
HUP0400529A2 (hu) 2004-06-28
EE200300212A (et) 2003-08-15
RU2286769C2 (ru) 2006-11-10

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