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SK288085B6 - Indole derivatives, medicament comprising said derivatives, use of said derivatives and process for their preparation - Google Patents

Indole derivatives, medicament comprising said derivatives, use of said derivatives and process for their preparation Download PDF

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Publication number
SK288085B6
SK288085B6 SK222-2003A SK2222003A SK288085B6 SK 288085 B6 SK288085 B6 SK 288085B6 SK 2222003 A SK2222003 A SK 2222003A SK 288085 B6 SK288085 B6 SK 288085B6
Authority
SK
Slovakia
Prior art keywords
formula
derivatives
indole
compound
methyl
Prior art date
Application number
SK222-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK2222003A3 (en
Inventor
Peter Emig
Gerald Bacher
Dietmar Reichert
Silke Baasner
Beate Aue
Bernd Nickel
Eckhard Gunther
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of SK2222003A3 publication Critical patent/SK2222003A3/sk
Publication of SK288085B6 publication Critical patent/SK288085B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
SK222-2003A 2000-07-28 2001-07-26 Indole derivatives, medicament comprising said derivatives, use of said derivatives and process for their preparation SK288085B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10037310A DE10037310A1 (de) 2000-07-28 2000-07-28 Neue Indolderivate und deren Verwendung als Arzneimittel
PCT/EP2001/008644 WO2002010152A2 (fr) 2000-07-28 2001-07-26 Nouveaux derives d'indol et leur utilisation comme medicaments

Publications (2)

Publication Number Publication Date
SK2222003A3 SK2222003A3 (en) 2004-04-06
SK288085B6 true SK288085B6 (sk) 2013-06-03

Family

ID=7650860

Family Applications (1)

Application Number Title Priority Date Filing Date
SK222-2003A SK288085B6 (sk) 2000-07-28 2001-07-26 Indole derivatives, medicament comprising said derivatives, use of said derivatives and process for their preparation

Country Status (31)

Country Link
US (3) US7365081B2 (fr)
EP (3) EP1309585B1 (fr)
JP (1) JP5113973B2 (fr)
KR (1) KR100810453B1 (fr)
CN (1) CN1215066C (fr)
AR (1) AR055209A1 (fr)
AT (1) ATE392420T1 (fr)
AU (2) AU2001289758B2 (fr)
BG (1) BG66457B1 (fr)
BR (1) BR0112807A (fr)
CA (3) CA2704693A1 (fr)
CY (1) CY1108770T1 (fr)
CZ (1) CZ304197B6 (fr)
DE (2) DE10037310A1 (fr)
DK (1) DK1309585T3 (fr)
ES (1) ES2303532T3 (fr)
HK (1) HK1058201A1 (fr)
HU (1) HU229254B1 (fr)
IL (2) IL153930A0 (fr)
MX (1) MXPA03000644A (fr)
NO (1) NO324594B1 (fr)
NZ (1) NZ524404A (fr)
PL (1) PL208673B1 (fr)
PT (1) PT1309585E (fr)
RU (1) RU2270196C9 (fr)
SI (1) SI1309585T1 (fr)
SK (1) SK288085B6 (fr)
TW (1) TWI291955B (fr)
UA (1) UA80670C2 (fr)
WO (1) WO2002010152A2 (fr)
ZA (1) ZA200300584B (fr)

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US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
NZ543853A (en) * 2003-06-05 2009-09-25 Zentaris Gmbh Indole derivatives with apoptosis-inducing effect
EP1484329A1 (fr) * 2003-06-06 2004-12-08 Zentaris GmbH Dérivés d'indole déstinés à l'induction d'apoptose
US7211588B2 (en) * 2003-07-25 2007-05-01 Zentaris Gmbh N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
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US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
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US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
CA2660704A1 (fr) 2006-08-07 2008-02-14 Ironwood Pharmaceuticals, Inc. Composes d'indole
US20110160249A1 (en) 2008-05-23 2011-06-30 Schaab Kevin Murray 5-lipoxygenase-activating protein inhibitor
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen

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US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
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Also Published As

Publication number Publication date
UA80670C2 (en) 2007-10-25
JP2004505075A (ja) 2004-02-19
US7365081B2 (en) 2008-04-29
ZA200300584B (en) 2003-07-18
IL153930A (en) 2008-11-03
EP1309585B1 (fr) 2008-04-16
SI1309585T1 (sl) 2008-08-31
WO2002010152A2 (fr) 2002-02-07
IL153930A0 (en) 2003-07-31
US8008324B2 (en) 2011-08-30
HU229254B1 (en) 2013-10-28
RU2270196C2 (ru) 2006-02-20
NO20030382L (no) 2003-02-20
PT1309585E (pt) 2008-06-09
DE50113867D1 (de) 2008-05-29
BR0112807A (pt) 2003-07-01
CZ304197B6 (cs) 2013-12-27
DK1309585T3 (da) 2008-06-23
EP1309585A2 (fr) 2003-05-14
HK1058201A1 (en) 2004-05-07
AU8975801A (en) 2002-02-13
US7989453B2 (en) 2011-08-02
PL208673B1 (pl) 2011-05-31
CA2354210A1 (fr) 2002-01-28
CZ2003500A3 (cs) 2004-03-17
BG66457B1 (bg) 2014-10-31
JP5113973B2 (ja) 2013-01-09
US20080108819A1 (en) 2008-05-08
WO2002010152A3 (fr) 2002-08-01
ES2303532T3 (es) 2008-08-16
NO324594B1 (no) 2007-11-26
ATE392420T1 (de) 2008-05-15
EP1939195A1 (fr) 2008-07-02
HUP0300677A2 (hu) 2003-11-28
CA2354210C (fr) 2010-09-14
CN1447805A (zh) 2003-10-08
MXPA03000644A (es) 2003-06-06
CN1215066C (zh) 2005-08-17
CY1108770T1 (el) 2014-04-09
TWI291955B (en) 2008-01-01
CA2704691A1 (fr) 2002-01-28
NZ524404A (en) 2004-08-27
US20030100597A1 (en) 2003-05-29
KR100810453B1 (ko) 2008-03-07
CA2704693A1 (fr) 2002-01-28
NO20030382D0 (no) 2003-01-24
KR20030017658A (ko) 2003-03-03
BG107560A (bg) 2003-10-31
SK2222003A3 (en) 2004-04-06
AR055209A1 (es) 2007-08-15
EP2163552A1 (fr) 2010-03-17
DE10037310A1 (de) 2002-02-07
RU2270196C9 (ru) 2007-11-27
AU2001289758B2 (en) 2006-07-06
PL361356A1 (en) 2004-10-04
US20080153875A1 (en) 2008-06-26

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20150726