[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AR055209A1 - Derivados del indol, uso de los mismos para la preparacion de medicamentos, procedimientos para prepararlos y los medicamentos que los contienen - Google Patents

Derivados del indol, uso de los mismos para la preparacion de medicamentos, procedimientos para prepararlos y los medicamentos que los contienen

Info

Publication number
AR055209A1
AR055209A1 ARP010103614A ARP010103614A AR055209A1 AR 055209 A1 AR055209 A1 AR 055209A1 AR P010103614 A ARP010103614 A AR P010103614A AR P010103614 A ARP010103614 A AR P010103614A AR 055209 A1 AR055209 A1 AR 055209A1
Authority
AR
Argentina
Prior art keywords
alkyl
mono
unsubstituted
alkoxy
halogen
Prior art date
Application number
ARP010103614A
Other languages
English (en)
Spanish (es)
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of AR055209A1 publication Critical patent/AR055209A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
ARP010103614A 2000-07-28 2001-07-27 Derivados del indol, uso de los mismos para la preparacion de medicamentos, procedimientos para prepararlos y los medicamentos que los contienen AR055209A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10037310A DE10037310A1 (de) 2000-07-28 2000-07-28 Neue Indolderivate und deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
AR055209A1 true AR055209A1 (es) 2007-08-15

Family

ID=7650860

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010103614A AR055209A1 (es) 2000-07-28 2001-07-27 Derivados del indol, uso de los mismos para la preparacion de medicamentos, procedimientos para prepararlos y los medicamentos que los contienen

Country Status (31)

Country Link
US (3) US7365081B2 (fr)
EP (3) EP1309585B1 (fr)
JP (1) JP5113973B2 (fr)
KR (1) KR100810453B1 (fr)
CN (1) CN1215066C (fr)
AR (1) AR055209A1 (fr)
AT (1) ATE392420T1 (fr)
AU (2) AU8975801A (fr)
BG (1) BG66457B1 (fr)
BR (1) BR0112807A (fr)
CA (3) CA2354210C (fr)
CY (1) CY1108770T1 (fr)
CZ (1) CZ304197B6 (fr)
DE (2) DE10037310A1 (fr)
DK (1) DK1309585T3 (fr)
ES (1) ES2303532T3 (fr)
HK (1) HK1058201A1 (fr)
HU (1) HU229254B1 (fr)
IL (2) IL153930A0 (fr)
MX (1) MXPA03000644A (fr)
NO (1) NO324594B1 (fr)
NZ (1) NZ524404A (fr)
PL (1) PL208673B1 (fr)
PT (1) PT1309585E (fr)
RU (1) RU2270196C9 (fr)
SI (1) SI1309585T1 (fr)
SK (1) SK288085B6 (fr)
TW (1) TWI291955B (fr)
UA (1) UA80670C2 (fr)
WO (1) WO2002010152A2 (fr)
ZA (1) ZA200300584B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52155013A (en) 1976-06-18 1977-12-23 Hitachi Ltd Image pickup unit
DE10037310A1 (de) * 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
AU2002323474B2 (en) 2001-09-13 2006-10-05 Synta Pharmaceuticals Corp 3-glyoxlylamideindoles for treating cancer
EP1484329A1 (fr) * 2003-06-06 2004-12-08 Zentaris GmbH Dérivés d'indole déstinés à l'induction d'apoptose
BRPI0410998A (pt) * 2003-06-05 2006-07-04 Zentaris Gmbh derivados de indol com efeito de indução de apoptose
US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
US7211588B2 (en) * 2003-07-25 2007-05-01 Zentaris Gmbh N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
EP2610244A1 (fr) 2006-08-07 2013-07-03 Ironwood Pharmaceuticals, Inc. Composés d'indole
BRPI0912267A2 (pt) 2008-05-23 2015-10-13 Amira Pharmaceuticals Inc sal farmaceuticamente aceitável, composição farmacêutica, artigo de fabricação, métodos para tratar asma, rinite alérgica, doença, lesões gástricas e dor, métodos para prevenir broncoconstrição e rinite alérgica, uso de um sal farmaceuticamente aceitável, e, processo para a preparação de um sal farmaceuticamente aceitável.
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3632M (fr) 1962-10-31 1965-10-25 Thomae Gmbh Dr K Dérivés de l'acide 6-amino-pénicillanique.
US6204261B1 (en) 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US3573294A (en) * 1968-03-14 1971-03-30 Glaxo Lab Ltd 7 - (arylglyoxamido)cephalosporanic acids and their salts and alpha-carbonyl derivatives
US5192770A (en) 1990-12-07 1993-03-09 Syntex (U.S.A.) Inc. Serotonergic alpha-oxoacetamides
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
AU3162695A (en) * 1994-08-03 1996-03-04 Asta Medica Aktiengesellschaft Indol, indazol, pyridopyrrol and pyridopyrazol derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effects
US5732113A (en) 1996-06-20 1998-03-24 Stanford University Timing and frequency synchronization of OFDM signals
DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
HUP0101146A3 (en) 1998-02-25 2001-11-28 Genetics Inst Llc Cambridge Indole derivatives as inhibitors of phospholipase enzymes and pharmaceutical compositions containing them
WO1999046267A1 (fr) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulateurs de proteine tyrosine phosphatases (ptpases)
DE19946301A1 (de) * 1998-04-02 2001-04-19 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit therapeutisch wertvollen Eigenschaften
DE19814838C2 (de) * 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
AU5947399A (en) 1998-04-27 1999-11-16 Hoechst Marion Roussel Deutschland Gmbh A new glucose-6-phosphate translocase inhibitor L 970885 from an actinomycete SP., and chemical derivatives thereof, a process for the preparation and theirv use as pharmaceuticals
HUP0101625A3 (en) 1998-04-28 2002-12-28 Elbion Ag New hydroxyindoles, their use as phosphodiesterase 4 inhibitors and method for producing same
EP1083918A1 (fr) 1998-06-08 2001-03-21 Advanced Medicine, Inc. Agents therapeutiques modulant les recepteurs 5-ht
CA2755266C (fr) 1998-06-17 2014-08-12 Eisai R&D Management Co., Ltd. Intermediaires pour la preparation d'analogues macrocycliques
GB9823871D0 (en) 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
WO2000031603A1 (fr) * 1998-11-19 2000-06-02 Infineon Technologies Ag Circuit pour produire une tension d'alimentation stabilisee destinee a plusieurs consommateurs
WO2000067802A1 (fr) 1999-05-10 2000-11-16 Protarga, Inc. Compositions d'acides gras -n-substituted indol-3-glyoxyl-amide et leur utilisation
DE60036868D1 (de) 1999-05-21 2007-12-06 Scios Inc Derivate des indol-typs als p38 kinase inhibitoren
AP2002002442A0 (en) 1999-08-12 2002-03-31 Pharmacia Italia Spa 3(5)-Amino-pyrazole derivatives, process for their preparation and their preparation and their use as antitumor agents.
WO2001017516A2 (fr) 1999-09-10 2001-03-15 Novo Nordisk A/S Procede d'inhibition de la proteine tyrosine phosphatase 1b et/ou de la proteine tyrosine phosphatase de lymphocytes et/ou d'autres ptpases possedant un reste aps en position 48
JP2003509429A (ja) 1999-09-10 2003-03-11 ノボ ノルディスク アクティーゼルスカブ タンパク質チロシンホスファターゼ（ｐｔｐアーゼ）のモジュレーター
TWI269654B (en) 1999-09-28 2007-01-01 Baxter Healthcare Sa N-substituted indole-3-glyoxylamide compounds having anti-tumor action
IT1315267B1 (it) 1999-12-23 2003-02-03 Novuspharma Spa Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale
DE19962300A1 (de) 1999-12-23 2001-06-28 Asta Medica Ag Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung
WO2001094310A1 (fr) 2000-06-07 2001-12-13 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Procedes de fabrication d'alcaloides bis-heterocycliques
DE10035927A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
IT1318641B1 (it) * 2000-07-25 2003-08-27 Novuspharma Spa Ammidi di acidi 2-(1h-indol-3-il)-2-oxo-acetici ad attivita'antitumorale.
DE10037310A1 (de) * 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
GB0525623D0 (en) 2005-12-16 2006-01-25 Hill Nicholas P R RFID reader
JP5241235B2 (ja) * 2007-02-28 2013-07-17 イビデン株式会社 ハニカム構造体の製造方法
WO2008105081A1 (fr) * 2007-02-28 2008-09-04 Ibiden Co., Ltd. Filtre en nid d'abeilles
WO2008105082A1 (fr) * 2007-02-28 2008-09-04 Ibiden Co., Ltd. Structure en nid d'abeilles
WO2008126334A1 (fr) * 2007-03-30 2008-10-23 Ibiden Co., Ltd. Procédé de production d'une structure en nid d'abeilles
WO2008126333A1 (fr) * 2007-03-30 2008-10-23 Ibiden Co., Ltd. Structure en nid d'abeilles
KR101025465B1 (ko) * 2007-03-30 2011-04-04 이비덴 가부시키가이샤 허니컴 구조체 및 허니컴 구조체의 제조 방법
WO2008139608A1 (fr) * 2007-05-14 2008-11-20 Ibiden Co., Ltd. Structure en nid d'abeille et procédé de production de la structure en nid d'abeille

Also Published As

Publication number Publication date
RU2270196C9 (ru) 2007-11-27
US7365081B2 (en) 2008-04-29
US20080108819A1 (en) 2008-05-08
DE10037310A1 (de) 2002-02-07
IL153930A0 (en) 2003-07-31
US20080153875A1 (en) 2008-06-26
KR100810453B1 (ko) 2008-03-07
MXPA03000644A (es) 2003-06-06
PL361356A1 (en) 2004-10-04
SK2222003A3 (en) 2004-04-06
DE50113867D1 (de) 2008-05-29
US8008324B2 (en) 2011-08-30
CA2704693A1 (fr) 2002-01-28
CY1108770T1 (el) 2014-04-09
IL153930A (en) 2008-11-03
AU8975801A (en) 2002-02-13
CA2354210C (fr) 2010-09-14
RU2270196C2 (ru) 2006-02-20
AU2001289758B2 (en) 2006-07-06
CZ2003500A3 (cs) 2004-03-17
BR0112807A (pt) 2003-07-01
ZA200300584B (en) 2003-07-18
WO2002010152A3 (fr) 2002-08-01
JP2004505075A (ja) 2004-02-19
NO20030382L (no) 2003-02-20
US7989453B2 (en) 2011-08-02
EP2163552A1 (fr) 2010-03-17
DK1309585T3 (da) 2008-06-23
BG107560A (bg) 2003-10-31
CN1447805A (zh) 2003-10-08
JP5113973B2 (ja) 2013-01-09
CA2354210A1 (fr) 2002-01-28
NO20030382D0 (no) 2003-01-24
BG66457B1 (bg) 2014-10-31
CN1215066C (zh) 2005-08-17
CZ304197B6 (cs) 2013-12-27
PL208673B1 (pl) 2011-05-31
KR20030017658A (ko) 2003-03-03
NZ524404A (en) 2004-08-27
HUP0300677A2 (hu) 2003-11-28
ATE392420T1 (de) 2008-05-15
PT1309585E (pt) 2008-06-09
NO324594B1 (no) 2007-11-26
ES2303532T3 (es) 2008-08-16
UA80670C2 (en) 2007-10-25
EP1309585A2 (fr) 2003-05-14
US20030100597A1 (en) 2003-05-29
HK1058201A1 (en) 2004-05-07
HU229254B1 (en) 2013-10-28
SI1309585T1 (sl) 2008-08-31
EP1939195A1 (fr) 2008-07-02
SK288085B6 (sk) 2013-06-03
CA2704691A1 (fr) 2002-01-28
TWI291955B (en) 2008-01-01
EP1309585B1 (fr) 2008-04-16
WO2002010152A2 (fr) 2002-02-07

Similar Documents

Publication Publication Date Title
AR055209A1 (es) Derivados del indol, uso de los mismos para la preparacion de medicamentos, procedimientos para prepararlos y los medicamentos que los contienen
AR058546A1 (es) Derivados de 2- adamantilurea como inhibidores selectivos de 11 beta - hsd1
AR033678A1 (es) Derivados de quinolina, procedimiento para prepararlos, uso de los mismos para la preparacion de medicamentos y los medicamentos que contienen dichos derivados
UY27522A1 (es) Inhibidores de pde9 para tratamiento de trastornos cardiovasculares
FI962954A (fi) Substituoidut 3-arylideeni-7-atsaoksindoliyhdisteet ja menetelmä niiden valmistamiseksi
PE20010964A1 (es) Derivados de tiazolilamida
AR063331A1 (es) Derivados de biaril eter urea y composiciones farmaceuticas
AR041566A1 (es) Derivados de indol utiles para el tratamiento de enfermedades
PE20061305A1 (es) Compuestos derivados de fenilacetamidas como inhibidores de proteincinasas
ES2496592T3 (es) Proceso para la preparación de Imatinib y compuestos intermedios del mismo
AR061973A1 (es) Compuesto de 2-arilindol sustituido en la posicion 5, composicion farmaceutica que lo comprende, compuestos intermedios y procedimiento para la preparacion de los mismos
FI943646A0 (fi) Bentsosyklohepteenejä, bentsoksepiinejä bentsotiepiinejä
AR051767A1 (es) Derivados de quinolina e isoquinolina 5-sustituidos un procedimiento para su preparacion y su uso como inhibidores de la inflamacion
AR036864A1 (es) Uso de compuestos de acido benzacepin-n-acetico, y procedimiento para la preparacion de dichos compuestos
AR019409A1 (es) Derivados de ftalacina utiles como inhibidores de la fosfodiestearasa 4 y composiciones farmaceuticas que incluyen dichos derivados
FI954016A0 (fi) Uudet yhdisteet
CO5660290A2 (es) 6-(1,1-difluoroalquil)-4-aminopicolinatos y su uso como herbicidas
AR031196A1 (es) Procedimiento para la preparacion de ciclopenta (b) (1,4)-diazepino (6,7,1-hi) indoles y derivados
ATE176232T1 (de) Verwendung dimethylbenzofuran und dimethylbenzopyran derivate als 5-ht3 antagoniste
ECSP034598A (es) Compuesto lactamico
AR068381A1 (es) Compuestos de quinolina apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6
AR041376A1 (es) Piperazinas sustituidas por heterociclos para el tratamiento de la esquizofrenia
DK1642576T3 (da) Anvendelse af pyrrolderivater til at bekæmpe angst
AR020773A1 (es) Compuesto derivados de 3-(tetrahidropiridin-4-il)indol, metodo para prepararlo, una composicion farmaceutica que los contiene, metodo para preparar dicha composicion y uso del compuesto
DE60122350D1 (de) Benzoesaüre derivate und deren verwendung

Legal Events

Date Code Title Description
FB Suspension of granting procedure