SI3672614T1 - Proizvedeni zunajcelični vezikli in njihova uporaba - Google Patents

Proizvedeni zunajcelični vezikli in njihova uporaba

Info

Publication number: SI3672614T1
Authority: SI; Slovenia
Prior art keywords: extracellular vesicles; engineered extracellular; engineered; vesicles; extracellular
Prior art date: 2018-11-16

Application number

SI201930182T

Other languages

English (en)

Inventor

Kevin P. Dooley

Rane A. Harrison

Ke Xu

Damian J. Houde

Sonya Haupt

John D. Kulman

Douglas E. Williams

Russell E. Mcconnell

Madeleine Youniss

Original Assignee

Codiak Biosciences, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-11-16

Filing date

2019-05-22

Publication date

2022-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=70732111&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3672614(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2018-11-16 Priority claimed from PCT/US2018/061679 external-priority patent/WO2019099942A1/en

2019-05-22 Application filed by Codiak Biosciences, Inc. filed Critical Codiak Biosciences, Inc.

2022-04-29 Publication of SI3672614T1 publication Critical patent/SI3672614T1/sl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Immunology (AREA)
Microbiology (AREA)
Engineering & Computer Science (AREA)
Mycology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Communicable Diseases (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SI201930182T 2018-11-16 2019-05-22 Proizvedeni zunajcelični vezikli in njihova uporaba SI3672614T1 (sl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
PCT/US2018/061679 WO2019099942A1 (en)	2017-11-17	2018-11-16	Compositions of engineered exosomes and methods of loading luminal exosomes payloads
US201962835430P	2019-04-17	2019-04-17
EP19731027.9A EP3672614B1 (en)	2018-11-16	2019-05-22	Engineered extracellular vesicles and uses thereof
PCT/US2019/033629 WO2020101740A1 (en)	2018-11-16	2019-05-22	Engineered extracellular vesicles and uses thereof

Publications (1)

Publication Number	Publication Date
SI3672614T1 true SI3672614T1 (sl)	2022-04-29

Family

ID=70732111

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI201930182T SI3672614T1 (sl)	2018-11-16	2019-05-22	Proizvedeni zunajcelični vezikli in njihova uporaba

Country Status (27)

Country	Link
EP (2)	EP3672614B1 (sl)
JP (2)	JP7538795B2 (sl)
KR (1)	KR20210098473A (sl)
CN (1)	CN113286603A (sl)
AU (1)	AU2019378591A1 (sl)
BR (1)	BR112021009231A2 (sl)
CA (1)	CA3119720A1 (sl)
CL (1)	CL2021001278A1 (sl)
CY (1)	CY1124897T1 (sl)
DK (1)	DK3672614T3 (sl)
EA (1)	EA202191334A1 (sl)
ES (1)	ES2907967T3 (sl)
HR (1)	HRP20220020T1 (sl)
HU (1)	HUE057300T2 (sl)
IL (1)	IL283167A (sl)
LT (1)	LT3672614T (sl)
MA (1)	MA49971B1 (sl)
MD (1)	MD3672614T2 (sl)
MX (1)	MX2021005636A (sl)
PH (1)	PH12021551088A1 (sl)
PL (1)	PL3672614T3 (sl)
PT (1)	PT3672614T (sl)
RS (1)	RS62863B1 (sl)
SG (1)	SG11202104956QA (sl)
SI (1)	SI3672614T1 (sl)
TW (1)	TWI846697B (sl)
WO (1)	WO2020101740A1 (sl)

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WO2021030768A1 (en)	2019-08-14	2021-02-18	Codiak Biosciences, Inc.	Extracellular vesicles with stat3-antisense oligonucleotides
BR112022002690A2 (pt)	2019-08-14	2022-08-23	Codiak Biosciences Inc	Construtos de vesícula-aso extracelular tendo como alvo cebp/beta
JP2022544290A (ja)	2019-08-14	2022-10-17	コディアックバイオサイエンシーズ，インコーポレイテッド	Ｋｒａｓを標的とするアンチセンスオリゴヌクレオチドを有する細胞外小胞
WO2021062057A1 (en)	2019-09-25	2021-04-01	Codiak Biosciences, Inc.	Exogenous loading of exosomes via lyophilization
CN114727947A (zh)	2019-09-25	2022-07-08	科迪亚克生物科学公司	细胞外囊泡组合物
WO2021062058A1 (en)	2019-09-25	2021-04-01	Codiak Biosciences, Inc.	Sting agonist comprising exosomes for treating neuroimmunological disorders
WO2021062290A1 (en)	2019-09-25	2021-04-01	Codiak Biosciences, Inc.	Methods of producing extracellular vesicles
EP4034150A1 (en)	2019-09-25	2022-08-03	Codiak BioSciences, Inc.	Sting agonist comprising exosomes combined with il-12 displaying exosomes for treating a tumour
CN115484990A (zh)	2020-03-12	2022-12-16	基础科学研究院	诱导具有基因组序列变异的细胞凋亡的组合物及使用组合物诱导细胞凋亡的方法
WO2021184020A1 (en)	2020-03-13	2021-09-16	Codiak Biosciences, Inc.	Methods of treating neuroinflammation
US20230114434A1 (en)	2020-03-13	2023-04-13	Codiak Biosciences, Inc.	Extracellular vesicles for treating neurological disorders
WO2021184021A1 (en)	2020-03-13	2021-09-16	Codiak Biosciences, Inc.	Extracellular vesicle-aso constructs targeting pmp22
JP2023518414A (ja)	2020-03-20	2023-05-01	コディアックバイオサイエンシーズ，インコーポレイテッド	治療のための細胞外小胞
WO2021248133A1 (en)	2020-06-05	2021-12-09	Codiak Biosciences, Inc.	Anti-transferrin extracellular vesicles
CN116209430A (zh) *	2020-08-07	2023-06-02	阿米库斯治疗学公司	囊泡靶向蛋白及其用途
WO2022066883A1 (en)	2020-09-23	2022-03-31	Codiak Biosciences, Inc.	Extracellular vesicles comprising kras antigens and uses thereof
US20240241020A1 (en)	2020-09-23	2024-07-18	Lonza Sales Ag	Process for preparing extracellular vesicles
WO2022066934A2 (en)	2020-09-23	2022-03-31	Codiak Biosciences, Inc.	Process for preparing extracellular vesicles
GB202015399D0 (en) *	2020-09-29	2020-11-11	Evox Therapeutics Ltd	Engineered extracellular vesicles displaying enhanced pharmacokinetics
WO2022076596A1 (en)	2020-10-06	2022-04-14	Codiak Biosciences, Inc.	Extracellular vesicle-aso constructs targeting stat6
CN112410304A (zh) *	2020-11-12	2021-02-26	天津大学	一种基因修饰的外泌体及其制备方法和应用
CN112899307A (zh) *	2021-01-28	2021-06-04	苏州大学	GluN1和/或GluN2亚基羧基末端豆蔻酰化的NMDA受体的应用
US20240167036A1 (en) *	2021-02-17	2024-05-23	Lonza Sales Ag	Extracellular vesicle-nlrp3 antagonist
WO2022178147A1 (en)	2021-02-17	2022-08-25	Codiak Biosciences, Inc.	Methods of loading extracellular vesicles
WO2022212884A1 (en)	2021-04-01	2022-10-06	Codiak Biosciences, Inc.	Extracellular vesicle compositions
CN114057893B (zh) *	2021-04-26	2022-12-30	苏州大学	一种编码线粒体定位的豆蔻酰化多肽及其制备方法与应用
CN117126886A (zh) *	2022-05-20	2023-11-28	谛邈生物科技(北京)有限公司	一种实现工程化EVs功能蛋白模块化装载的核酸构建体及其应用
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2019
- 2019-05-22 JP JP2021526563A patent/JP7538795B2/ja active Active
- 2019-05-22 ES ES19731027T patent/ES2907967T3/es active Active
- 2019-05-22 CN CN201980083366.0A patent/CN113286603A/zh active Pending
- 2019-05-22 CA CA3119720A patent/CA3119720A1/en active Pending
- 2019-05-22 WO PCT/US2019/033629 patent/WO2020101740A1/en unknown
- 2019-05-22 SG SG11202104956QA patent/SG11202104956QA/en unknown
- 2019-05-22 EP EP19731027.9A patent/EP3672614B1/en active Active
- 2019-05-22 HU HUE19731027A patent/HUE057300T2/hu unknown
- 2019-05-22 HR HRP20220020TT patent/HRP20220020T1/hr unknown
- 2019-05-22 EA EA202191334A patent/EA202191334A1/ru unknown
- 2019-05-22 MX MX2021005636A patent/MX2021005636A/es unknown
- 2019-05-22 AU AU2019378591A patent/AU2019378591A1/en active Pending
- 2019-05-22 EP EP21200884.1A patent/EP4059510A1/en active Pending
- 2019-05-22 DK DK19731027.9T patent/DK3672614T3/da active
- 2019-05-22 PT PT197310279T patent/PT3672614T/pt unknown
- 2019-05-22 SI SI201930182T patent/SI3672614T1/sl unknown
- 2019-05-22 LT LTEPPCT/US2019/033629T patent/LT3672614T/lt unknown
- 2019-05-22 BR BR112021009231-5A patent/BR112021009231A2/pt unknown
- 2019-05-22 MD MDE20200694T patent/MD3672614T2/ro unknown
- 2019-05-22 MA MA49971A patent/MA49971B1/fr unknown
- 2019-05-22 KR KR1020217018358A patent/KR20210098473A/ko active Search and Examination
- 2019-05-22 PL PL19731027T patent/PL3672614T3/pl unknown
- 2019-05-22 RS RS20220009A patent/RS62863B1/sr unknown
- 2019-05-23 TW TW108117910A patent/TWI846697B/zh active
2021
- 2021-05-11 PH PH12021551088A patent/PH12021551088A1/en unknown
- 2021-05-13 IL IL283167A patent/IL283167A/en unknown
- 2021-05-14 CL CL2021001278A patent/CL2021001278A1/es unknown
2022
- 2022-01-07 CY CY20221100020T patent/CY1124897T1/el unknown
2024
- 2024-05-10 JP JP2024077013A patent/JP2024097929A/ja active Pending

Also Published As

Publication number	Publication date
MA49971A (fr)	2020-07-01
MX2021005636A (es)	2021-07-06
PH12021551088A1 (en)	2022-01-03
IL283167A (en)	2021-06-30
HRP20220020T1 (hr)	2022-04-01
EP4059510A1 (en)	2022-09-21
EP3672614A1 (en)	2020-07-01
TWI846697B (zh)	2024-07-01
ES2907967T3 (es)	2022-04-27
LT3672614T (lt)	2022-04-11
PT3672614T (pt)	2022-02-11
RS62863B1 (sr)	2022-02-28
BR112021009231A2 (pt)	2021-08-10
MA49971B1 (fr)	2022-01-31
KR20210098473A (ko)	2021-08-10
WO2020101740A1 (en)	2020-05-22
CA3119720A1 (en)	2020-05-22
DK3672614T3 (da)	2022-01-10
PL3672614T3 (pl)	2022-03-07
WO2020101740A9 (en)	2021-06-10
CN113286603A (zh)	2021-08-20
EP3672614B1 (en)	2021-10-06
CY1124897T1 (el)	2023-01-05
CL2021001278A1 (es)	2022-03-11
TW202038993A (zh)	2020-11-01
HUE057300T2 (hu)	2022-05-28
MD3672614T2 (ro)	2022-04-30
JP2024097929A (ja)	2024-07-19
SG11202104956QA (en)	2021-06-29
EA202191334A1 (ru)	2022-02-10
JP2022513049A (ja)	2022-02-07
AU2019378591A1 (en)	2021-06-17
JP7538795B2 (ja)	2024-08-22

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EP3411820A4 (en)	2019-09-25	FABRIC WITH PROVISION OF CONTINUOUS SAFETY
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