SI2601949T1 - Farmacevtski sestavek, ki vsebuje (1S)-1,5-anhidro-1-(5-(4-etoksibenzil)-2-metoksi-4-metilfenil)-1-tio-d- glukitol in sekretagog inzulina - Google Patents

Farmacevtski sestavek, ki vsebuje (1S)-1,5-anhidro-1-(5-(4-etoksibenzil)-2-metoksi-4-metilfenil)-1-tio-d- glukitol in sekretagog inzulina

Info

Publication number: SI2601949T1
Authority: SI; Slovenia
Prior art keywords: methylphenylć; ethoxybenzyl; glucitol; anhydro; thio
Prior art date: 2009-04-16

Application number

SI201030784T

Other languages

English (en)

Inventor

Teisuke Takahashi

Saeko Uchida

Original Assignee

Taisho Pharmaceutical Co., Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-04-16

Filing date

2010-04-16

Publication date

2014-12-31

2010-04-16 Application filed by Taisho Pharmaceutical Co., Ltd. filed Critical Taisho Pharmaceutical Co., Ltd.

2014-12-31 Publication of SI2601949T1 publication Critical patent/SI2601949T1/sl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI201030784T 2009-04-16 2010-04-16 Farmacevtski sestavek, ki vsebuje (1S)-1,5-anhidro-1-(5-(4-etoksibenzil)-2-metoksi-4-metilfenil)-1-tio-d- glukitol in sekretagog inzulina SI2601949T1 (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2009100210		2009-04-16
EP13157571.4A EP2601949B1 (en)	2009-04-16	2010-04-16	Pharmaceutical compositions with (1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol and an insulin secretagogue.

Publications (1)

Publication Number	Publication Date
SI2601949T1 true SI2601949T1 (sl)	2014-12-31

Family

ID=42982643

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SI201030365T SI2419097T1 (sl)	2009-04-16	2010-04-16	Farmacevtski sestavek, ki vsebuje (1S)-1,5-anhidro-1-(5-(4-etoksibenzil)-2-metoksi-4-metilfenil)-1-tio-d- glukitol in metformin in njegove uporabe pri zdravljenju diabetesa
SI201030784T SI2601949T1 (sl)	2009-04-16	2010-04-16	Farmacevtski sestavek, ki vsebuje (1S)-1,5-anhidro-1-(5-(4-etoksibenzil)-2-metoksi-4-metilfenil)-1-tio-d- glukitol in sekretagog inzulina

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SI201030365T SI2419097T1 (sl)	2009-04-16	2010-04-16	Farmacevtski sestavek, ki vsebuje (1S)-1,5-anhidro-1-(5-(4-etoksibenzil)-2-metoksi-4-metilfenil)-1-tio-d- glukitol in metformin in njegove uporabe pri zdravljenju diabetesa

Country Status (30)

Country	Link
US (1)	US20120040898A1 (sl)
EP (3)	EP2829271A3 (sl)
JP (4)	JP5077786B2 (sl)
KR (2)	KR20150046382A (sl)
CN (7)	CN105343060A (sl)
AR (1)	AR076317A1 (sl)
AU (1)	AU2010237748B2 (sl)
BR (1)	BRPI1012539A2 (sl)
CA (1)	CA2755392A1 (sl)
CY (2)	CY1114703T1 (sl)
DK (2)	DK2601949T3 (sl)
ES (2)	ES2523408T3 (sl)
HK (6)	HK1217302A1 (sl)
HR (2)	HRP20131120T1 (sl)
ME (2)	ME02015B (sl)
MX (1)	MX2011010901A (sl)
MY (3)	MY182720A (sl)
NZ (4)	NZ606888A (sl)
PH (3)	PH12015500235B1 (sl)
PL (2)	PL2419097T3 (sl)
PT (2)	PT2601949E (sl)
RS (2)	RS53761B1 (sl)
RU (2)	RU2532330C2 (sl)
SG (6)	SG2014012462A (sl)
SI (2)	SI2419097T1 (sl)
SM (1)	SMT201500015B (sl)
TW (3)	TW201103534A (sl)
UA (2)	UA111742C2 (sl)
WO (1)	WO2010119990A1 (sl)
ZA (1)	ZA201106727B (sl)

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US7772191B2 (en)	2005-05-10	2010-08-10	Boehringer Ingelheim International Gmbh	Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
KR101813025B1 (ko)	2009-09-30	2017-12-28	베링거 인겔하임 인터내셔날 게엠베하	글루코피라노실치환된 벤질벤젠 유도체의 제조방법
US10610489B2 (en)	2009-10-02	2020-04-07	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
US20120283169A1 (en) *	2010-11-08	2012-11-08	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
TR201101809A1 (tr) *	2010-12-21	2012-07-23	Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇	Vildagliptin ve glimepirid kombinasyonları.
US9192617B2 (en)	2012-03-20	2015-11-24	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
JP6234443B2 (ja)	2012-05-17	2017-11-22	ブイティーブイ・セラピューティクス・エルエルシー	糖尿病治療のためのグルコキナーゼ活性化因子組成物
WO2014034842A1 (ja)	2012-08-30	2014-03-06	大正製薬株式会社	Ｓｇｌｔ２阻害薬と抗高血圧薬との組み合わせ
US11813275B2 (en)	2013-04-05	2023-11-14	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
HUE041709T2 (hu)	2013-04-05	2019-05-28	Boehringer Ingelheim Int	Az empagliflozin terápiás alkalmazásai
US20140303097A1 (en)	2013-04-05	2014-10-09	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
SI2986304T1 (sl)	2013-04-18	2022-04-29	Boehringer Ingelheim International Gmbh	Farmacevtski sestavek, postopki za zdravljenje in njegove uporabe
TW201636015A (zh) *	2013-07-05	2016-10-16	卡地拉保健有限公司	協同性組成物
BR112017018329A2 (pt) *	2015-02-27	2018-08-07	The Asan Foundation	composição para prevenir ou tratar calcificação de válvula, contendo inibidor de dpp-4
CN105963280B (zh) *	2016-06-30	2018-11-06	合肥华方医药科技有限公司	一种伏格列波糖口腔速溶膜及其制备方法
EP3528800A1 (en)	2016-10-19	2019-08-28	Boehringer Ingelheim International GmbH	Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof
CN110168098A (zh) *	2016-11-14	2019-08-23	高雄医学大学	一种检测糖代谢异常的方法及其预防及治疗
EP3781166A1 (en)	2018-04-17	2021-02-24	Boehringer Ingelheim International GmbH	Pharmaceutical composition, methods for treating and uses thereof
KR20190137343A (ko)	2018-06-01	2019-12-11	김유찬	계량 인덕션
KR20210020866A (ko)	2018-06-12	2021-02-24	브이티브이 테라퓨틱스 엘엘씨	인슐린 또는 인슐린 유사체와 조합된 글루코키나제 활성제의 치료적 용도

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DE4432757A1 (de)	1994-09-14	1996-03-21	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
JP2003520759A (ja)	1999-08-31	2003-07-08	アンドルックスファーマスーティカルズインコーポレーテッド	単位核を有する徐放性錠剤
DE60231295D1 (de) *	2001-04-04	2009-04-09	Ortho Mcneil Janssen Pharm	R und ppar modulatoren
CA2444481A1 (en) *	2001-04-11	2002-10-24	Bristol-Myers Squibb Company	Amino acid complexes of c-aryl glucosides for treatment of diabetes and method
TW200637839A (en) *	2005-01-07	2006-11-01	Taisho Pharmaceutical Co Ltd	1-thio-d-glucitol derivatives
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JP5194588B2 (ja) *	2006-07-06	2013-05-08	大正製薬株式会社	１−チオ−ｄ−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤
JP5384343B2 (ja) *	2006-08-15	2014-01-08	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	グルコピラノシル−置換シクロプロピルベンゼン誘導体、そのような化合物を含む医薬組成物、ｓｇｌｔ阻害剤としてのそれらの使用及びそれらの製造方法
CA3007700A1 (en) *	2006-11-09	2008-05-15	Boehringer Ingelheim International Gmbh	Combination therapy with sglt-2 inhibitors and their pharmaceutical compositions
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PE20090938A1 (es)	2007-08-16	2009-08-08	Boehringer Ingelheim Int	Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
PE20090603A1 (es)	2007-08-16	2009-06-11	Boehringer Ingelheim Int	Composicion farmaceutica que comprende un inhibidor de sglt2 y un inhibidor de dpp iv

2010
- 2010-04-16 NZ NZ606888A patent/NZ606888A/en not_active IP Right Cessation
- 2010-04-16 CN CN201510876708.8A patent/CN105343060A/zh active Pending
- 2010-04-16 PL PL10764570T patent/PL2419097T3/pl unknown
- 2010-04-16 UA UAA201314870A patent/UA111742C2/uk unknown
- 2010-04-16 RU RU2011146335/15A patent/RU2532330C2/ru not_active IP Right Cessation
- 2010-04-16 ME MEP-2015-6A patent/ME02015B/me unknown
- 2010-04-16 MX MX2011010901A patent/MX2011010901A/es active IP Right Grant
- 2010-04-16 SG SG2014012462A patent/SG2014012462A/en unknown
- 2010-04-16 ES ES13157571.4T patent/ES2523408T3/es active Active
- 2010-04-16 SG SG2014014807A patent/SG2014014807A/en unknown
- 2010-04-16 TW TW099111992A patent/TW201103534A/zh unknown
- 2010-04-16 SG SG2014015093A patent/SG2014015093A/en unknown
- 2010-04-16 ME MEP-2013-137A patent/ME01555B/me unknown
- 2010-04-16 WO PCT/JP2010/057196 patent/WO2010119990A1/en active Application Filing
- 2010-04-16 PL PL13157571T patent/PL2601949T3/pl unknown
- 2010-04-16 SI SI201030365T patent/SI2419097T1/sl unknown
- 2010-04-16 CA CA2755392A patent/CA2755392A1/en not_active Abandoned
- 2010-04-16 CN CN201510876753.3A patent/CN105434430A/zh active Pending
- 2010-04-16 MY MYPI2015001283A patent/MY182720A/en unknown
- 2010-04-16 RS RS20150042A patent/RS53761B1/en unknown
- 2010-04-16 BR BRPI1012539A patent/BRPI1012539A2/pt not_active IP Right Cessation
- 2010-04-16 SG SG2014012553A patent/SG2014012553A/en unknown
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Also Published As

Publication number	Publication date
DK2601949T3 (da)	2015-01-05
TW201103534A (en)	2011-02-01
UA111742C2 (uk)	2016-06-10
MX2011010901A (es)	2011-11-01
PL2419097T3 (pl)	2014-02-28
JP5077786B2 (ja)	2012-11-21
HK1218881A1 (zh)	2017-03-17
PL2601949T3 (pl)	2015-04-30
CN105434430A (zh)	2016-03-30
TW201500043A (zh)	2015-01-01
MY182720A (en)	2021-02-03
UA105216C2 (en)	2014-04-25
SG2014012405A (en)	2014-05-29
CN105343059A (zh)	2016-02-24
NZ606888A (en)	2014-07-25
JP5910711B2 (ja)	2016-04-27
EP2601949A3 (en)	2013-09-18
CA2755392A1 (en)	2010-10-21
SG2014015093A (en)	2014-04-28
MY183793A (en)	2021-03-16
SG2014014807A (en)	2014-05-29
BRPI1012539A2 (pt)	2016-03-29
PH12015500235A1 (en)	2015-12-02
NZ623838A (en)	2015-09-25
RU2011146335A (ru)	2013-05-27
SI2419097T1 (sl)	2014-01-31
PT2601949E (pt)	2014-11-12
CN102395364A (zh)	2012-03-28
JP5660094B2 (ja)	2015-01-28
PH12019500959B1 (en)	2020-06-29
HRP20131120T1 (hr)	2013-12-20
PH12015500235B1 (en)	2015-12-02
RS53056B (en)	2014-04-30
DK2419097T3 (da)	2013-10-28
NZ595314A (en)	2013-03-28
PH12019500961B1 (en)	2020-08-03
JP6066144B2 (ja)	2017-01-25
EP2601949A2 (en)	2013-06-12
JP2016104775A (ja)	2016-06-09
TW201622720A (zh)	2016-07-01
EP2419097B1 (en)	2013-09-25
CY1115907T1 (el)	2017-01-25
KR20120016051A (ko)	2012-02-22
US20120040898A1 (en)	2012-02-16
SG2014012553A (en)	2014-05-29
EP2419097A1 (en)	2012-02-22
CY1114703T1 (el)	2016-10-05
HK1217434A1 (zh)	2017-01-13
NZ710575A (en)	2016-06-24
SMT201500015B (it)	2015-03-05
EP2601949B1 (en)	2014-10-29
EP2829271A3 (en)	2015-05-27
CN105343060A (zh)	2016-02-24
ES2523408T3 (es)	2014-11-25
HK1217301A1 (zh)	2017-01-06
MY156679A (en)	2016-03-15
JP2015063543A (ja)	2015-04-09
JP2013006854A (ja)	2013-01-10
ME02015B (me)	2015-05-20
SG175154A1 (en)	2011-11-28
AU2010237748B2 (en)	2014-10-30
RU2532330C2 (ru)	2014-11-10
WO2010119990A1 (en)	2010-10-21
ZA201106727B (en)	2012-11-28
KR20150046382A (ko)	2015-04-29
PH12019500961A1 (en)	2020-08-03
EP2829271A2 (en)	2015-01-28
HRP20141080T1 (hr)	2015-01-02
HK1218871A1 (zh)	2017-03-17
SG2014012462A (en)	2014-05-29
EP2419097A4 (en)	2012-09-05
HK1217435A1 (zh)	2017-01-13
CN105343871A (zh)	2016-02-24
CN105477639A (zh)	2016-04-13
AR076317A1 (es)	2011-06-01
ME01555B (me)	2014-04-20
RU2014121260A (ru)	2015-12-10
PH12019500959A1 (en)	2020-06-29
AU2010237748A1 (en)	2011-10-20
ES2431300T3 (es)	2013-11-25
RS53761B1 (en)	2015-06-30
JP2012524710A (ja)	2012-10-18
HK1217302A1 (zh)	2017-01-06
CN105343880A (zh)	2016-02-24
PT2419097E (pt)	2013-10-03

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