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SI2694072T2 - Kombinacija spojine, ki zavira AKT, in abiraterona za uporabo pri terapevtskem zdravljenju - Google Patents

Kombinacija spojine, ki zavira AKT, in abiraterona za uporabo pri terapevtskem zdravljenju

Info

Publication number
SI2694072T2
SI2694072T2 SI201231202T SI201231202T SI2694072T2 SI 2694072 T2 SI2694072 T2 SI 2694072T2 SI 201231202 T SI201231202 T SI 201231202T SI 201231202 T SI201231202 T SI 201231202T SI 2694072 T2 SI2694072 T2 SI 2694072T2
Authority
SI
Slovenia
Prior art keywords
abiraterone
combination
inhibitor compound
therapeutic treatments
akt inhibitor
Prior art date
Application number
SI201231202T
Other languages
English (en)
Other versions
SI2694072T1 (sl
Inventor
Michelle Nannini
Deepak Sampath
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46931958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2694072(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of SI2694072T1 publication Critical patent/SI2694072T1/sl
Publication of SI2694072T2 publication Critical patent/SI2694072T2/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SI201231202T 2011-04-01 2012-03-30 Kombinacija spojine, ki zavira AKT, in abiraterona za uporabo pri terapevtskem zdravljenju SI2694072T2 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161470803P 2011-04-01 2011-04-01
US201161470624P 2011-04-01 2011-04-01
PCT/US2012/031679 WO2012135759A1 (en) 2011-04-01 2012-03-30 Combinations of akt inhibitor compounds and abiraterone, and methods of use
EP12764765.9A EP2694072B2 (en) 2011-04-01 2012-03-30 Combination of akt inhibitor compound and abiraterone for use in therapeutic treatments

Publications (2)

Publication Number Publication Date
SI2694072T1 SI2694072T1 (sl) 2018-03-30
SI2694072T2 true SI2694072T2 (sl) 2024-10-30

Family

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Family Applications (1)

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SI201231202T SI2694072T2 (sl) 2011-04-01 2012-03-30 Kombinacija spojine, ki zavira AKT, in abiraterona za uporabo pri terapevtskem zdravljenju

Country Status (28)

Country Link
US (7) US20150064171A1 (sl)
EP (4) EP2694070A4 (sl)
JP (4) JP6239497B2 (sl)
KR (4) KR101950044B1 (sl)
CN (8) CN112915092A (sl)
AU (4) AU2012236166A1 (sl)
BR (4) BR112013025386B1 (sl)
CA (4) CA2844699C (sl)
DK (1) DK2694072T4 (sl)
ES (3) ES2620644T3 (sl)
FI (1) FI2694072T4 (sl)
HK (2) HK1199244A1 (sl)
HR (1) HRP20180223T4 (sl)
HU (1) HUE036513T2 (sl)
IL (4) IL228641A0 (sl)
LT (1) LT2694072T (sl)
ME (1) ME02998B (sl)
MX (4) MX354509B (sl)
MY (1) MY179607A (sl)
PL (2) PL2694072T3 (sl)
PT (1) PT2694072T (sl)
RS (1) RS56759B2 (sl)
RU (4) RU2631240C2 (sl)
SG (5) SG10201504303SA (sl)
SI (1) SI2694072T2 (sl)
TR (1) TR201802093T4 (sl)
WO (4) WO2012135759A1 (sl)
ZA (4) ZA201308064B (sl)

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US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
MY172151A (en) 2008-01-04 2019-11-14 Intellikine Llc Certain chemical entities, compositions and methods
KR20160079934A (ko) 2008-06-16 2016-07-06 유니버시티 오브 테네시 리서치 파운데이션 암 치료용 화합물
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
BR112013017670B1 (pt) 2011-01-10 2022-07-19 Infinity Pharmaceuticals, Inc Processos de preparação de isoquinolinonas e formas sólidas de isoquinolinonas
SG191724A1 (en) 2011-01-11 2013-08-30 Glaxosmithkline Llc Combination
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