SI2650008T1 - Uporaba celično permeabilnih peptidnih inhibitorjev poti transdukcije JNK signala za zdravljenje različnih rakastih obolenj - Google Patents
Uporaba celično permeabilnih peptidnih inhibitorjev poti transdukcije JNK signala za zdravljenje različnih rakastih obolenjInfo
- Publication number
- SI2650008T1 SI2650008T1 SI200931118T SI200931118T SI2650008T1 SI 2650008 T1 SI2650008 T1 SI 2650008T1 SI 200931118 T SI200931118 T SI 200931118T SI 200931118 T SI200931118 T SI 200931118T SI 2650008 T1 SI2650008 T1 SI 2650008T1
- Authority
- SI
- Slovenia
- Prior art keywords
- treatment
- signal transduction
- transduction pathway
- various cancer
- peptide inhibitors
- Prior art date
Links
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Organic Chemistry (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2008/004341 WO2009143865A1 (en) | 2008-05-30 | 2008-05-30 | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
EP20130002793 EP2650008B1 (en) | 2008-05-30 | 2009-06-02 | Use of cell permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various cancer diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2650008T1 true SI2650008T1 (sl) | 2015-03-31 |
Family
ID=40347935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200931118T SI2650008T1 (sl) | 2008-05-30 | 2009-06-02 | Uporaba celično permeabilnih peptidnih inhibitorjev poti transdukcije JNK signala za zdravljenje različnih rakastih obolenj |
Country Status (17)
Country | Link |
---|---|
US (2) | US9006185B2 (sl) |
EP (6) | EP2650008B1 (sl) |
JP (3) | JP5485265B2 (sl) |
CN (2) | CN102112149A (sl) |
AR (1) | AR070864A1 (sl) |
AU (1) | AU2009253346B2 (sl) |
CA (1) | CA2725545A1 (sl) |
CY (4) | CY1114725T1 (sl) |
DK (5) | DK2489361T3 (sl) |
ES (5) | ES2481915T3 (sl) |
HK (6) | HK1150305A1 (sl) |
HR (1) | HRP20150116T1 (sl) |
HU (1) | HUE026798T2 (sl) |
PL (5) | PL2650008T3 (sl) |
PT (4) | PT2489361E (sl) |
SI (1) | SI2650008T1 (sl) |
WO (2) | WO2009143865A1 (sl) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US8080517B2 (en) | 2005-09-12 | 2011-12-20 | Xigen Sa | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
WO2007031098A1 (en) | 2005-09-12 | 2007-03-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the jnk signal transduction pathway |
AR069501A1 (es) | 2007-11-30 | 2010-01-27 | Genentech Inc | Anticuerpos anti- vegf (factor de crecimiento endotelial vascular) |
WO2009143865A1 (en) * | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
WO2009143864A1 (en) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases |
US9101645B2 (en) | 2008-10-22 | 2015-08-11 | Genentech, Inc. | Modulation of axon degeneration |
WO2010065850A2 (en) * | 2008-12-04 | 2010-06-10 | University Of Massachusetts | Interleukin 6 and tumor necrosis factor alpha as biomarkers of jnk inhibition |
WO2010072228A1 (en) | 2008-12-22 | 2010-07-01 | Xigen S.A. | Novel transporter constructs and transporter cargo conjugate molecules |
WO2011160653A1 (en) | 2010-06-21 | 2011-12-29 | Xigen S.A. | Novel jnk inhibitor molecules |
WO2012048721A1 (en) * | 2010-10-14 | 2012-04-19 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases |
EP2902035B1 (en) * | 2010-10-14 | 2018-06-20 | Xigen Inflammation Ltd. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway for use in the treatment of inflammatory eye diseases. |
CN101974083A (zh) * | 2010-10-20 | 2011-02-16 | 中国医学科学院医学生物学研究所 | 抗hsv1病毒感染的人源hirrp蛋白分子 |
WO2013091670A1 (en) * | 2011-12-21 | 2013-06-27 | Xigen S.A. | Novel jnk inhibitor molecules for treatment of various diseases |
WO2014206427A1 (en) * | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
AU2014301631A1 (en) * | 2013-06-26 | 2015-08-27 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
WO2015197098A1 (en) * | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
WO2016055160A2 (en) * | 2014-10-08 | 2016-04-14 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
WO2015197097A1 (en) * | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
WO2014206426A1 (en) * | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
CN103911462B (zh) * | 2014-04-03 | 2015-06-10 | 河北国际旅行卫生保健中心 | 黄热、乙型脑炎、基孔肯雅、西尼罗的鉴别检测方法及引物和探针 |
CN106414504B (zh) * | 2014-04-04 | 2020-12-18 | 马尔科·费利焦尼 | 用于治疗由谷氨酸兴奋性毒性引起的疾病的细胞可渗透肽系统 |
EP3160989A2 (en) * | 2014-06-26 | 2017-05-03 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
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2014
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- 2014-01-07 HK HK14100161.7A patent/HK1186988A1/xx not_active IP Right Cessation
- 2014-02-19 JP JP2014029875A patent/JP5824085B2/ja not_active Expired - Fee Related
- 2014-07-03 CY CY20141100500T patent/CY1115357T1/el unknown
-
2015
- 2015-01-30 HR HRP20150116AT patent/HRP20150116T1/hr unknown
- 2015-02-19 CY CY20151100178T patent/CY1116175T1/el unknown
- 2015-03-06 US US14/640,759 patent/US9610330B2/en active Active
- 2015-07-17 JP JP2015143202A patent/JP2015232008A/ja active Pending
- 2015-07-23 CY CY20151100649T patent/CY1116633T1/el unknown
-
2016
- 2016-08-11 HK HK16109616.7A patent/HK1221413A1/zh unknown
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