SI0994872T1 - - Google Patents
Info
- Publication number
- SI0994872T1 SI0994872T1 SI9730138T SI9730138T SI0994872T1 SI 0994872 T1 SI0994872 T1 SI 0994872T1 SI 9730138 T SI9730138 T SI 9730138T SI 9730138 T SI9730138 T SI 9730138T SI 0994872 T1 SI0994872 T1 SI 0994872T1
- Authority
- SI
- Slovenia
- Prior art keywords
- alkyl
- halo
- alkoxy
- trifluoroalkyl
- alkynyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/NL1997/000328 WO1998056787A1 (de) | 1997-06-10 | 1997-06-10 | 4-Phenylpiperidin-Derivate |
US08/872,023 US5874447A (en) | 1997-06-10 | 1997-06-10 | 4-Phenylpiperidine compounds for treating depression |
EP97926276A EP0994872B9 (de) | 1997-06-10 | 1997-06-10 | 4-phenylpiperidin-derivate |
Publications (1)
Publication Number | Publication Date |
---|---|
SI0994872T1 true SI0994872T1 (de) | 2001-08-31 |
Family
ID=26647319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9730138T SI0994872T1 (de) | 1997-06-10 | 1997-06-10 |
Country Status (26)
Country | Link |
---|---|
US (4) | US5874447A (de) |
EP (2) | EP0994872B9 (de) |
JP (1) | JP2002503248A (de) |
KR (1) | KR100543614B1 (de) |
AT (1) | ATE200781T1 (de) |
AU (1) | AU3108097A (de) |
BG (1) | BG64315B1 (de) |
BR (1) | BR9714787A (de) |
CA (1) | CA2293247C (de) |
CZ (1) | CZ295301B6 (de) |
DE (2) | DE69704679T2 (de) |
DK (1) | DK0994872T3 (de) |
EE (2) | EE03970B1 (de) |
ES (1) | ES2155995T3 (de) |
GR (1) | GR3035784T3 (de) |
HK (1) | HK1027352A1 (de) |
HU (1) | HUP0003141A3 (de) |
IL (1) | IL133366A (de) |
IS (2) | IS1927B (de) |
NO (3) | NO317371B1 (de) |
PL (1) | PL188450B1 (de) |
PT (1) | PT994872E (de) |
SI (1) | SI0994872T1 (de) |
SK (1) | SK283394B6 (de) |
TR (2) | TR200201156T2 (de) |
WO (1) | WO1998056787A1 (de) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
EP1073652A1 (de) * | 1998-04-09 | 2001-02-07 | Smithkline Beecham Plc | Paroxetin-maleat |
GB9814316D0 (en) * | 1998-07-02 | 1998-09-02 | Smithkline Beecham Plc | Novel compounds |
CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
US20010023252A1 (en) * | 1998-07-02 | 2001-09-20 | Smithkline Beecham Plc | Novel compound |
AU724845B3 (en) * | 1998-07-02 | 2000-09-28 | Smithkline Beecham Plc | Novel compound |
WO2000008016A1 (en) * | 1998-08-08 | 2000-02-17 | Smithkline Beecham Plc | Paroxetine salts |
GB9827431D0 (en) * | 1998-12-11 | 1999-02-03 | Smithkline Beecham Plc | Novel compound |
GB9828781D0 (en) * | 1998-12-29 | 1999-02-17 | Smithkline Beecham Plc | Novel process |
GB9828779D0 (en) * | 1998-12-29 | 1999-02-17 | Smithkline Beecham Plc | Novel process |
GB9828780D0 (en) * | 1998-12-29 | 1999-02-17 | Smithkline Beecham Plc | Novel process |
ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
WO2000078290A2 (en) * | 1999-06-22 | 2000-12-28 | Smithkline Beecham P.L.C. | Pharmaceutical composition comprising a salt of paroxetine |
GB9914585D0 (en) * | 1999-06-22 | 1999-08-25 | Smithkline Beecham Plc | Novel process |
CA2341984A1 (en) * | 1999-07-01 | 2001-01-11 | Paolo Mascagni | Complexes of paroxetine, with cyclodextrines or cyclodextrin derivatives |
GB9919052D0 (en) * | 1999-08-12 | 1999-10-13 | Smithkline Beecham Plc | Novel compound composition and process |
US6503927B1 (en) * | 1999-10-28 | 2003-01-07 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
EP1280775A1 (de) * | 2000-05-12 | 2003-02-05 | Synthon B.V. | Tosylsalzen von 4-(p-fluorophenyl)-piperidine-3-carbinolen |
ES2209876T3 (es) * | 2000-05-12 | 2004-07-01 | Synthon B.V. | Compuestos de piperidina y procedimiento para su preparacion. |
CA2418038A1 (en) * | 2000-08-28 | 2002-03-07 | Synthon B.V. | Paroxetine compositions and processes for making the same |
AU2001286232A1 (en) * | 2000-09-14 | 2002-03-26 | Asahi Glass Company, Limited | Process for producing paroxetine salt containing substantially no organic solvent |
DE20100529U1 (de) * | 2001-01-11 | 2001-05-10 | Synthon Bv | Pharmazeutische Tablette umfassend Paroxetinmesylat |
US6720003B2 (en) * | 2001-02-16 | 2004-04-13 | Andrx Corporation | Serotonin reuptake inhibitor formulations |
NL1017421C2 (nl) * | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
WO2002085360A1 (en) * | 2001-04-25 | 2002-10-31 | Pentech Pharmaceuticals, Inc. | Optimized procedures for the manufacture of paroxetine salts |
CA2457382A1 (en) * | 2001-06-13 | 2002-12-19 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of paroxetine substantially free of alkoxy impurities |
IL159280A0 (en) * | 2001-06-14 | 2004-06-01 | Teva Pharma | A process for preparing paroxetine hcl which limits formation of pink colored compounds |
EP1412350A1 (de) * | 2001-08-02 | 2004-04-28 | Spurcourt Limited | Paroxetin isethionatsalz, herstellungsverfahren und anwendung bei der behandlung von depression |
US20030181488A1 (en) | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof |
AR039163A1 (es) * | 2002-03-28 | 2005-02-09 | Synthon Bv | Besilato de venlafaxina |
US20040220153A1 (en) * | 2002-09-24 | 2004-11-04 | Jost-Price Edward Roydon | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
US7202259B2 (en) * | 2002-11-18 | 2007-04-10 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
PT1691811E (pt) | 2003-12-11 | 2014-10-30 | Sunovion Pharmaceuticals Inc | Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão |
WO2006018318A1 (en) * | 2004-08-18 | 2006-02-23 | Synthon B.V. | Liquid paroxetine compositions |
WO2006023347A1 (en) * | 2004-08-20 | 2006-03-02 | Alpharma, Inc. | Paroxetine formulations |
US20080033011A1 (en) * | 2005-07-29 | 2008-02-07 | Concert Pharmaceuticals Inc. | Novel benzo[d][1,3]-dioxol derivatives |
CN101273024A (zh) * | 2005-07-29 | 2008-09-24 | 康瑟特制药公司 | 新颖苯并[d][1,3]-二氧杂环戊烯衍生物 |
SE529246C2 (sv) | 2005-10-13 | 2007-06-12 | Neurosearch Sweden Ab | Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission |
AU2006315684A1 (en) * | 2005-11-14 | 2007-05-24 | Auspex Pharmaceuticals, Inc. | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties |
US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
EP2200997B9 (de) | 2007-09-13 | 2016-01-13 | Concert Pharmaceuticals Inc. | Synthese deuterierter Benzodioxole |
US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
JP6038128B2 (ja) | 2011-06-03 | 2016-12-07 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー |
AR089837A1 (es) * | 2012-01-31 | 2014-09-17 | Eisai R&D Man Co Ltd | Derivado de paroxetina |
EP2844346B1 (de) | 2012-04-04 | 2020-01-01 | Prilenia Neurotherapeutics Ltd. | Pharmazeutische zusammensetzungen für eine kombinationstherapie |
HRP20221047T1 (hr) | 2014-08-28 | 2022-11-11 | Eisai R&D Management Co., Ltd. | Derivat kinolina visoke čistoće i postupak za njegovu proizvodnju |
HUE064614T2 (hu) | 2015-02-25 | 2024-04-28 | Eisai R&D Man Co Ltd | Eljárás egy kinolin-származék keserû ízének elnyomására |
US11369623B2 (en) | 2015-06-16 | 2022-06-28 | Prism Pharma Co., Ltd. | Anticancer combination of a CBP/catenin inhibitor and an immune checkpoint inhibitor |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT99678B (de) * | 1921-09-21 | 1925-04-10 | Hoechst Ag | Verfahren zur Darstellung arzneilich wirksamer Quecksilberverbindungen. |
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
US4585777A (en) * | 1984-02-07 | 1986-04-29 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT |
GB8430581D0 (en) * | 1984-12-04 | 1985-01-09 | Ferrosan As | Treatment |
EP0190496A3 (de) * | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Piperidinderivate mit gastro-intestinaler Wirkung |
DE3680184D1 (de) * | 1985-08-10 | 1991-08-14 | Beecham Group Plc | Verfahren zur herstellung von arylpiperidincarbinol. |
GB8520154D0 (en) * | 1985-08-10 | 1985-09-18 | Beecham Group Plc | Chemical process |
EP0223403B1 (de) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel |
US5258388A (en) | 1986-03-17 | 1993-11-02 | University Of Florida | Anticholinergic compounds, compositions and methods of treatment |
IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
GB8626936D0 (en) * | 1986-11-11 | 1986-12-10 | Ferrosan As | Treatment |
GB8714707D0 (en) * | 1987-06-23 | 1987-07-29 | Beecham Group Plc | Chemical process |
DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
EP0558679A1 (de) | 1990-11-24 | 1993-09-08 | BEECHAM GROUP plc | Verwendung von paroxetin zur behandlung von seniler demenz, bulimia, migräne oder anorexia |
GB9209687D0 (en) * | 1992-05-06 | 1992-06-17 | Smithkline Beecham Plc | Novel process |
US5258517A (en) * | 1992-08-06 | 1993-11-02 | Sepracor, Inc. | Method of preparing optically pure precursors of paroxetine |
JP2773587B2 (ja) * | 1992-11-30 | 1998-07-09 | 東レ株式会社 | O,o´−ジアシル酒石酸無水物の製造法 |
US5276042A (en) | 1993-04-16 | 1994-01-04 | Crenshaw Roger T | Treatment of premature ejaculation |
US5546683A (en) * | 1993-09-29 | 1996-08-20 | Clark; George J. | Bucket attachment device with remote controlled retractable pins |
IT1274241B (it) * | 1993-12-03 | 1997-07-15 | Smithkline Beecham Farma | Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono |
GB9325644D0 (en) | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
US5668134A (en) * | 1994-01-28 | 1997-09-16 | G. D. Searle & Co. | Method for preventing or reducing photosensitivity and/or phototoxicity reactions to medications |
GB9402029D0 (en) * | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
CA2143070C (en) * | 1994-02-22 | 2001-12-18 | Pankaj Modi | Oral controlled release liquid suspension pharmaceutical formulation |
EP0714663A3 (de) * | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potenzierung von Wirkstoffresponz durch Serotonin 1A Rezeptor Antagonisten |
JPH08220486A (ja) * | 1994-12-14 | 1996-08-30 | Kato Kogei:Kk | 眼鏡フレーム |
US5856493A (en) * | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
AR001982A1 (es) * | 1995-02-06 | 1998-01-07 | Smithkline Beecham Plc | Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion |
GB2297550C2 (en) * | 1995-02-06 | 1997-04-09 | Smithkline Beecham Plc | Paroxetine hydrochloride anhydrate substantially free of bound organic solvent |
EP0818990A1 (de) * | 1995-04-03 | 1998-01-21 | Abbott Laboratories | Homogene mischungen aus niedrigschmelzenden arzneistoffen und additiven zur verzögerten wirkstoffeingabe |
HUP9900318A3 (en) * | 1995-05-17 | 2001-09-28 | Novo Nordisk As | Process for preparing 4-aryl-piperidine derivatives |
JP2813768B2 (ja) * | 1995-05-24 | 1998-10-22 | 農林水産省家畜衛生試験場長 | 口蹄疫診断用ペプチドおよび当該ペプチドを含有する口蹄疫診断用抗原 |
GB9514842D0 (en) * | 1995-07-20 | 1995-09-20 | Smithkline Beecham Plc | Novel formulation |
AU701386B2 (en) * | 1995-10-31 | 1999-01-28 | Merck & Co., Inc. | Process for preparing substituted azetidinones |
IT1276160B1 (it) * | 1995-11-22 | 1997-10-27 | Recordati Chem Pharm | Composizioni farmaceutiche orali a pronto rilascio per sospensioni estemporanee |
GB9526645D0 (en) * | 1995-12-28 | 1996-02-28 | Chiroscience Ltd | Stereoselective synthesis |
ES2117557B1 (es) * | 1996-02-29 | 1999-07-01 | Ferrer Int | Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina. |
JP3446468B2 (ja) * | 1996-04-15 | 2003-09-16 | 旭硝子株式会社 | ピペリジンカルビノール類の製造方法 |
CA2206592A1 (en) * | 1996-05-30 | 1997-11-30 | Shu-Zhong Wang | Method of producing amorphous paroxetine hydrochloride |
JP3882224B2 (ja) * | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
EP1384720A1 (de) * | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Verfahren zur Trocknung von Paroxetinhydrochlorid |
HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
US5672609A (en) * | 1996-07-18 | 1997-09-30 | Eli Lilly And Company | Pyridine compounds, intermediates compositions and methods of use |
CA2187128A1 (en) * | 1996-10-04 | 1997-06-26 | K. S. Keshava Murthy | New and useful polymorph of anhydrous paroxetine hydrochloride |
US5955475A (en) * | 1997-06-30 | 1999-09-21 | Endo Pharmaceuticals Inc. | Process for manufacturing paroxetine solid dispersions |
CH689805A8 (fr) | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
-
1997
- 1997-06-10 EP EP97926276A patent/EP0994872B9/de not_active Expired - Lifetime
- 1997-06-10 ES ES97926276T patent/ES2155995T3/es not_active Expired - Lifetime
- 1997-06-10 PL PL97336895A patent/PL188450B1/pl not_active IP Right Cessation
- 1997-06-10 PT PT97926276T patent/PT994872E/pt unknown
- 1997-06-10 HU HU0003141A patent/HUP0003141A3/hu unknown
- 1997-06-10 EP EP00203910A patent/EP1078925A1/de not_active Withdrawn
- 1997-06-10 KR KR1019997011625A patent/KR100543614B1/ko not_active IP Right Cessation
- 1997-06-10 TR TR2002/01156T patent/TR200201156T2/xx unknown
- 1997-06-10 DE DE69704679T patent/DE69704679T2/de not_active Expired - Lifetime
- 1997-06-10 JP JP50212699A patent/JP2002503248A/ja not_active Ceased
- 1997-06-10 CZ CZ19994295A patent/CZ295301B6/cs not_active IP Right Cessation
- 1997-06-10 DE DE29724281U patent/DE29724281U1/de not_active Expired - Lifetime
- 1997-06-10 WO PCT/NL1997/000328 patent/WO1998056787A1/de active IP Right Grant
- 1997-06-10 US US08/872,023 patent/US5874447A/en not_active Expired - Lifetime
- 1997-06-10 DK DK97926276T patent/DK0994872T3/da active
- 1997-06-10 TR TR1999/03025T patent/TR199903025T2/xx unknown
- 1997-06-10 EE EEP199900570A patent/EE03970B1/xx not_active IP Right Cessation
- 1997-06-10 EE EEP200200633A patent/EE200200633A/xx unknown
- 1997-06-10 IL IL13336697A patent/IL133366A/xx not_active IP Right Cessation
- 1997-06-10 AT AT97926276T patent/ATE200781T1/de not_active IP Right Cessation
- 1997-06-10 AU AU31080/97A patent/AU3108097A/en not_active Abandoned
- 1997-06-10 SK SK1619-99A patent/SK283394B6/sk unknown
- 1997-06-10 SI SI9730138T patent/SI0994872T1/xx unknown
- 1997-06-10 CA CA002293247A patent/CA2293247C/en not_active Expired - Lifetime
- 1997-06-10 BR BR9714787-7A patent/BR9714787A/pt unknown
-
1998
- 1998-11-30 US US09/200,743 patent/US7598271B1/en not_active Expired - Lifetime
-
1999
- 1999-11-08 NO NO19995455A patent/NO317371B1/no unknown
- 1999-11-16 IS IS5249A patent/IS1927B/is unknown
- 1999-12-10 BG BG103980A patent/BG64315B1/bg unknown
-
2000
- 2000-10-10 HK HK00106418A patent/HK1027352A1/xx not_active IP Right Cessation
-
2001
- 2001-04-26 GR GR20010400220T patent/GR3035784T3/el not_active IP Right Cessation
- 2001-05-16 US US09/855,710 patent/US6900327B2/en not_active Expired - Lifetime
-
2003
- 2003-08-25 NO NO20033765A patent/NO20033765D0/no not_active Application Discontinuation
- 2003-08-25 NO NO20033766A patent/NO20033766D0/no not_active Application Discontinuation
-
2004
- 2004-01-08 IS IS7098A patent/IS7098A/is unknown
-
2009
- 2009-01-23 US US12/358,997 patent/US20090326233A1/en not_active Abandoned
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