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SE9802973D0 - Immediate release tablet - Google Patents

Immediate release tablet

Info

Publication number
SE9802973D0
SE9802973D0 SE9802973A SE9802973A SE9802973D0 SE 9802973 D0 SE9802973 D0 SE 9802973D0 SE 9802973 A SE9802973 A SE 9802973A SE 9802973 A SE9802973 A SE 9802973A SE 9802973 D0 SE9802973 D0 SE 9802973D0
Authority
SE
Sweden
Prior art keywords
immediate release
release tablet
formulation
fillers
filler
Prior art date
Application number
SE9802973A
Other languages
English (en)
Inventor
Sigbrit Forsman
Christer Karlsson
Magnus Karlsson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9802973A priority Critical patent/SE9802973D0/sv
Publication of SE9802973D0 publication Critical patent/SE9802973D0/sv
Priority to TW088114460A priority patent/TW561056B/zh
Priority to US09/424,740 priority patent/US6521253B1/en
Priority to HU0103886A priority patent/HU227278B1/hu
Priority to PT99946527T priority patent/PT1109537E/pt
Priority to NZ539749A priority patent/NZ539749A/en
Priority to SI9930748T priority patent/SI1109537T1/xx
Priority to BR9913400-4A priority patent/BR9913400A/pt
Priority to CNB998103365A priority patent/CN1158070C/zh
Priority to ES99946527T priority patent/ES2234296T3/es
Priority to EP99946527A priority patent/EP1109537B1/en
Priority to SK281-2001A priority patent/SK285507B6/sk
Priority to AU58924/99A priority patent/AU746129B2/en
Priority to DE69923074T priority patent/DE69923074T2/de
Priority to AT99946527T priority patent/ATE286385T1/de
Priority to CNA200410038573XA priority patent/CN1544088A/zh
Priority to KR1020067017052A priority patent/KR20060097071A/ko
Priority to EEP200100134A priority patent/EE200100134A/xx
Priority to CA002341397A priority patent/CA2341397C/en
Priority to CZ20010774A priority patent/CZ300830B6/cs
Priority to DK99946527T priority patent/DK1109537T3/da
Priority to UA2001021082A priority patent/UA75567C2/uk
Priority to NZ509943A priority patent/NZ509943A/en
Priority to TR2005/02188T priority patent/TR200502188T2/xx
Priority to PL99346545A priority patent/PL195603B1/pl
Priority to CNA2006100996728A priority patent/CN1951371A/zh
Priority to IDW20010429A priority patent/ID29629A/id
Priority to IL14143999A priority patent/IL141439A0/xx
Priority to RU2001104423/15A priority patent/RU2252751C2/ru
Priority to PCT/SE1999/001471 priority patent/WO2000013671A1/en
Priority to JP2000568480A priority patent/JP4026678B2/ja
Priority to TR2001/00666T priority patent/TR200100666T2/xx
Priority to EP04030515A priority patent/EP1527787A1/en
Priority to KR1020017002726A priority patent/KR100696350B1/ko
Priority to MYPI99003778A priority patent/MY124359A/en
Priority to ARP990104423A priority patent/AR029313A1/es
Priority to SA99200683A priority patent/SA99200683B1/ar
Priority to IL141439A priority patent/IL141439A/en
Priority to IS5869A priority patent/IS5869A/is
Priority to ZA200101762A priority patent/ZA200101762B/xx
Priority to NO20011085A priority patent/NO20011085L/no
Priority to US10/347,968 priority patent/US6875446B2/en
Priority to RU2005100986/15A priority patent/RU2005100986A/ru
Priority to US11/095,933 priority patent/US20050208128A1/en
Priority to JP2006309957A priority patent/JP2007039472A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE9802973A 1998-09-03 1998-09-03 Immediate release tablet SE9802973D0 (sv)

Priority Applications (45)

Application Number Priority Date Filing Date Title
SE9802973A SE9802973D0 (sv) 1998-09-03 1998-09-03 Immediate release tablet
TW088114460A TW561056B (en) 1998-09-03 1999-08-24 Oral immediate release formulation of the thrombin inhibitor
KR1020017002726A KR100696350B1 (ko) 1998-09-03 1999-08-27 급속 방출 정제
DK99946527T DK1109537T3 (da) 1998-09-03 1999-08-27 Oral formulering med öjeblikkelig frigivelse omfattende peptid-thrombininhibitorer og en kombination af mikrokrystallinsk cellulose og natriumstivelsesglycolat
NZ509943A NZ509943A (en) 1998-09-03 1999-08-27 Immediate release tablet for low molecular weight peptide based thrombin inhibitors
PT99946527T PT1109537E (pt) 1998-09-03 1999-08-27 Formulacao oral de libertacao imediata compreendendo inibidores peptidicos de trombina e uma combinacao de celulose microcristalina e glicolato de amido de sodio
NZ539749A NZ539749A (en) 1998-09-03 1999-08-27 Immediate release tablets of thrombin inhibitors i.e. melagatran and inogatran comprsing strach and cellulose as fillers
SI9930748T SI1109537T1 (en) 1998-09-03 1999-08-27 Immediate release oral formulation comprising peptide thrombin inhibitors and a combination of microcrystalline cellulose and sodium starch glycollate
BR9913400-4A BR9913400A (pt) 1998-09-03 1999-08-27 Formulação oral de liberação imediata na forma sólida de um inibidor de trombina, uso de um inibidor de trombina baseado em peptìdeo de baixo peso molecular, processos para a profilaxia e/ou o tratamento de trombo-embolismo, e para a preparação de uma formulação oral de liberação imediata, e, uso de uma carga escolhida do grupo consistindo de um derivado de celulose, e um derivado de amido
CNB998103365A CN1158070C (zh) 1998-09-03 1999-08-27 即时释放片剂
ES99946527T ES2234296T3 (es) 1998-09-03 1999-08-27 Formulacion oral de liberacion inmediata que comprende inhibidores peptidicos de trombina y una combinacion de celulosa microcristalina y almidon-glicolato de sodio.
EP99946527A EP1109537B1 (en) 1998-09-03 1999-08-27 Immediate release oral formulation comprising peptide thrombin inhibitors and a combination of microcrystalline cellulose and sodium starch glycollate
SK281-2001A SK285507B6 (sk) 1998-09-03 1999-08-27 Orálny prípravok na okamžité uvoľňovanie v pevnejforme, spôsob jeho prípravy a jeho použitie
AU58924/99A AU746129B2 (en) 1998-09-03 1999-08-27 Immediate release tablet
DE69923074T DE69923074T2 (de) 1998-09-03 1999-08-27 Oral anzuwendendes rasch-freisetzendes arzneimittel enthaltend peptid-thrombinhemmer und eine mischung von mikrokristallinen zellulose und natrium stärke glycollaten
AT99946527T ATE286385T1 (de) 1998-09-03 1999-08-27 Oral anzuwendendes rasch-freisetzendes arzneimittel enthaltend peptid-thrombinhemmer und eine mischung von mikrokristallinen zellulose und natrium stärke glycollaten
CNA200410038573XA CN1544088A (zh) 1998-09-03 1999-08-27 即时释放片剂
KR1020067017052A KR20060097071A (ko) 1998-09-03 1999-08-27 급속 방출 정제
EEP200100134A EE200100134A (et) 1998-09-03 1999-08-27 Kiiresti vabastav tablett
CA002341397A CA2341397C (en) 1998-09-03 1999-08-27 Immediate release tablet
PL99346545A PL195603B1 (pl) 1998-09-03 1999-08-27 Preparat doustny o natychmiastowym uwalnianiu, zastosowanie niskocząsteczkowego peptydowego inhibitora trombiny, sposób wytwarzania preparatu doustnego oraz zastosowanie mieszaniny celulozy mikrokrystalicznej i soli sodowej glikolanu skrobi
US09/424,740 US6521253B1 (en) 1998-09-03 1999-08-27 Immediate release tablet
UA2001021082A UA75567C2 (en) 1998-09-03 1999-08-27 Oral formulation containing thrombin inhibitor, process for their manufacture and method for preventing and treating thrombembolism
TR2005/02188T TR200502188T2 (tr) 1998-09-03 1999-08-27 Hemen yayılan tablet
CZ20010774A CZ300830B6 (cs) 1998-09-03 1999-08-27 Orální prostredek s bezprostredním uvolnováním v tuhé forme, pro profylaxi a/nebo lécení tromboembolie a zpusob jeho výroby
HU0103886A HU227278B1 (en) 1998-09-03 1999-08-27 Immediate release tablet comprising a peptide-base trombin inhibitor process for their preparation and their use
CNA2006100996728A CN1951371A (zh) 1998-09-03 1999-08-27 即时释放片剂
IDW20010429A ID29629A (id) 1998-09-03 1999-08-27 Tablet yang lapas-segera
IL14143999A IL141439A0 (en) 1998-09-03 1999-08-27 Immediate release tablet
RU2001104423/15A RU2252751C2 (ru) 1998-09-03 1999-08-27 Таблетка с немедленным высвобождением
PCT/SE1999/001471 WO2000013671A1 (en) 1998-09-03 1999-08-27 Immediate release tablet
JP2000568480A JP4026678B2 (ja) 1998-09-03 1999-08-27 速放性錠剤
TR2001/00666T TR200100666T2 (tr) 1998-09-03 1999-08-27 Hemen yayılan tablet.
EP04030515A EP1527787A1 (en) 1998-09-03 1999-08-27 Immediate release tablet
MYPI99003778A MY124359A (en) 1998-09-03 1999-09-01 Immediate release tablet
ARP990104423A AR029313A1 (es) 1998-09-03 1999-09-02 Formulacion oral de liberacion inmediata en forma solida. uso de un inhibidor de trombina peptidico de bajo peso molecular para la elaboracion de dicha formulacion. metodo para la profilaxis y/o tratamiento de la tromboembolia y proceso para la preparacion de dicha formulacion
SA99200683A SA99200683B1 (ar) 1998-09-03 1999-10-18 صيغ لإطلاق الفوري تعطي عن طريق الفم تشتمل على مثبطات ثرومبين ببتيدي peptide thrombin inhbitor وتوليفة من بلورات دقيقة من السليولوز microystalline cellulose وجليكولات صوديوم نشوية glycollate sodium starch
IL141439A IL141439A (en) 1998-09-03 2001-02-15 An immediate-release tablet
IS5869A IS5869A (is) 1998-09-03 2001-02-28 Hraðlosandi tafla
ZA200101762A ZA200101762B (en) 1998-09-03 2001-03-01 Immediate release tablet.
NO20011085A NO20011085L (no) 1998-09-03 2001-03-02 Tablett med umiddelbar frigivningsvirkning
US10/347,968 US6875446B2 (en) 1998-09-03 2003-01-21 Method for prophylaxis and/or treatment of thromboembolism
RU2005100986/15A RU2005100986A (ru) 1998-09-03 2005-01-19 Таблетка с немедленным высвобождением
US11/095,933 US20050208128A1 (en) 1998-09-03 2005-03-31 Immediate release tablet
JP2006309957A JP2007039472A (ja) 1998-09-03 2006-11-16 速放性錠剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9802973A SE9802973D0 (sv) 1998-09-03 1998-09-03 Immediate release tablet

Publications (1)

Publication Number Publication Date
SE9802973D0 true SE9802973D0 (sv) 1998-09-03

Family

ID=20412467

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9802973A SE9802973D0 (sv) 1998-09-03 1998-09-03 Immediate release tablet

Country Status (32)

Country Link
US (3) US6521253B1 (sv)
EP (2) EP1527787A1 (sv)
JP (2) JP4026678B2 (sv)
KR (2) KR20060097071A (sv)
CN (3) CN1158070C (sv)
AR (1) AR029313A1 (sv)
AT (1) ATE286385T1 (sv)
AU (1) AU746129B2 (sv)
BR (1) BR9913400A (sv)
CA (1) CA2341397C (sv)
CZ (1) CZ300830B6 (sv)
DE (1) DE69923074T2 (sv)
EE (1) EE200100134A (sv)
ES (1) ES2234296T3 (sv)
HU (1) HU227278B1 (sv)
ID (1) ID29629A (sv)
IL (2) IL141439A0 (sv)
IS (1) IS5869A (sv)
MY (1) MY124359A (sv)
NO (1) NO20011085L (sv)
NZ (2) NZ539749A (sv)
PL (1) PL195603B1 (sv)
PT (1) PT1109537E (sv)
RU (2) RU2252751C2 (sv)
SA (1) SA99200683B1 (sv)
SE (1) SE9802973D0 (sv)
SK (1) SK285507B6 (sv)
TR (2) TR200502188T2 (sv)
TW (1) TW561056B (sv)
UA (1) UA75567C2 (sv)
WO (1) WO2000013671A1 (sv)
ZA (1) ZA200101762B (sv)

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AR034517A1 (es) * 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
SE0103369D0 (sv) * 2001-10-09 2001-10-09 Astrazeneca Ab Pharmaceutical formulation
FR2833493B1 (fr) * 2001-12-18 2005-09-23 Ioltechnologie Production Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble
US20030181488A1 (en) 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
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SE0201659D0 (sv) * 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
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SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
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WO2000013671A1 (en) 2000-03-16
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AU5892499A (en) 2000-03-27
IL141439A (en) 2006-07-05
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KR20010090436A (ko) 2001-10-18
JP4026678B2 (ja) 2007-12-26
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ATE286385T1 (de) 2005-01-15
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US20030118644A1 (en) 2003-06-26
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CN1544088A (zh) 2004-11-10
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