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SE386672B - Mellanprodukter for framstellning av isokinolinderivat - Google Patents

Mellanprodukter for framstellning av isokinolinderivat

Info

Publication number
SE386672B
SE386672B SE7313623A SE1362373A SE386672B SE 386672 B SE386672 B SE 386672B SE 7313623 A SE7313623 A SE 7313623A SE 1362373 A SE1362373 A SE 1362373A SE 386672 B SE386672 B SE 386672B
Authority
SE
Sweden
Prior art keywords
isokinoline
derivatives
manufacture
intermediate products
products
Prior art date
Application number
SE7313623A
Other languages
English (en)
Swedish (sv)
Inventor
Jr A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE386672B publication Critical patent/SE386672B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7313623A 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat SE386672B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
SE386672B true SE386672B (sv) 1976-08-16

Family

ID=4179328

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7313623A SE386672B (sv) 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat
SE17063/70A SE368401B (xx) 1970-01-06 1970-12-16
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE17063/70A SE368401B (xx) 1970-01-06 1970-12-16
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Country Status (19)

Country Link
JP (1) JPS5515476B1 (xx)
AT (1) AT303041B (xx)
BE (1) BE761219A (xx)
CA (1) CA999866A (xx)
CH (2) CH538477A (xx)
DE (1) DE2062001C2 (xx)
DK (1) DK125021B (xx)
ES (1) ES387016A1 (xx)
FI (1) FI49503C (xx)
FR (1) FR2081412B1 (xx)
GB (1) GB1335261A (xx)
IE (1) IE34859B1 (xx)
IL (1) IL35916A (xx)
NL (1) NL171444C (xx)
NO (1) NO135315C (xx)
PH (1) PH9682A (xx)
SE (3) SE386672B (xx)
YU (1) YU33660B (xx)
ZA (1) ZA708590B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
CA2389300C (en) * 1999-11-03 2010-06-08 Albany Molecular Research, Inc. 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1246806B1 (en) 1999-11-03 2008-02-27 AMR Technology, Inc. Arly- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
JP5132864B2 (ja) 2000-07-11 2013-01-30 アルバニー モレキュラー リサーチ， インコーポレイテッド ４−フェニル置換テトラヒドロイソキノリンおよびその使用方法
GEP20094640B (en) 2004-07-15 2009-03-10 Bristol Myers Squibb Co Aryl-and heteroaryl-substituted tetrahydro isoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
DE602006002894D1 (de) 2005-06-17 2008-11-06 Janssen Pharmaceutica Nv Naphthyridinverbindungen
CN101495184A (zh) 2005-07-15 2009-07-29 Amr科技公司 芳基和杂芳基取代的四氢苯并氮杂及其在阻断去甲肾上腺素多巴胺和血清素的重摄取中的应用
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
MX2011011901A (es) 2009-05-12 2012-01-20 Albany Molecular Res Inc Tetrahidroisoquinolinas aril, heteroaril, y heterociclo sustituidas y uso de las mismas.
US8802696B2 (en) 2009-05-12 2014-08-12 Albany Molecular Research, Inc. 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
CA999866A (en) 1976-11-16
NO135315C (xx) 1977-03-23
IE34859B1 (en) 1975-09-03
IL35916A0 (en) 1971-02-25
NO135315B (xx) 1976-12-13
FR2081412B1 (xx) 1974-04-12
ZA708590B (en) 1971-09-29
AT303041B (de) 1972-11-10
IE34859L (en) 1971-07-06
NL171444B (nl) 1982-11-01
GB1335261A (en) 1973-10-24
IL35916A (en) 1973-11-28
JPS5515476B1 (xx) 1980-04-23
SE399879B (sv) 1978-03-06
NL7018956A (xx) 1971-07-08
YU1971A (en) 1977-06-30
NL171444C (nl) 1983-04-05
YU33660B (en) 1977-12-31
CH527194A (de) 1972-08-31
DE2062001A1 (de) 1971-07-15
PH9682A (en) 1976-02-10
DE2062001C2 (de) 1986-10-16
BE761219A (fr) 1971-07-05
ES387016A1 (es) 1976-05-01
SE368401B (xx) 1974-07-01
CH538477A (de) 1973-06-30
DK125021B (da) 1972-12-18
FI49503C (fi) 1975-07-10
FI49503B (xx) 1975-04-01
FR2081412A1 (xx) 1971-12-03

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