SE399879B - Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat - Google Patents
Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivatInfo
- Publication number
- SE399879B SE399879B SE7313622A SE7313622A SE399879B SE 399879 B SE399879 B SE 399879B SE 7313622 A SE7313622 A SE 7313622A SE 7313622 A SE7313622 A SE 7313622A SE 399879 B SE399879 B SE 399879B
- Authority
- SE
- Sweden
- Prior art keywords
- isokinoline
- tetrahydro
- phenyl
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH10370A CH527194A (de) | 1970-01-06 | 1970-01-06 | Verfahren zur Herstellung von Isochinolin-Derivaten |
Publications (1)
Publication Number | Publication Date |
---|---|
SE399879B true SE399879B (sv) | 1978-03-06 |
Family
ID=4179328
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7313623A SE386672B (sv) | 1970-01-06 | 1970-12-16 | Mellanprodukter for framstellning av isokinolinderivat |
SE17063/70A SE368401B (sv) | 1970-01-06 | 1970-12-16 | |
SE7313622A SE399879B (sv) | 1970-01-06 | 1973-10-05 | Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7313623A SE386672B (sv) | 1970-01-06 | 1970-12-16 | Mellanprodukter for framstellning av isokinolinderivat |
SE17063/70A SE368401B (sv) | 1970-01-06 | 1970-12-16 |
Country Status (19)
Country | Link |
---|---|
JP (1) | JPS5515476B1 (sv) |
AT (1) | AT303041B (sv) |
BE (1) | BE761219A (sv) |
CA (1) | CA999866A (sv) |
CH (2) | CH527194A (sv) |
DE (1) | DE2062001C2 (sv) |
DK (1) | DK125021B (sv) |
ES (1) | ES387016A1 (sv) |
FI (1) | FI49503C (sv) |
FR (1) | FR2081412B1 (sv) |
GB (1) | GB1335261A (sv) |
IE (1) | IE34859B1 (sv) |
IL (1) | IL35916A (sv) |
NL (1) | NL171444C (sv) |
NO (1) | NO135315C (sv) |
PH (1) | PH9682A (sv) |
SE (3) | SE386672B (sv) |
YU (1) | YU33660B (sv) |
ZA (1) | ZA708590B (sv) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4595688A (en) * | 1983-06-23 | 1986-06-17 | Mcneilab, Inc. | Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof |
US4719216A (en) * | 1983-06-23 | 1988-01-12 | Mcneilab, Inc. | Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants |
ZA844402B (en) * | 1983-06-23 | 1986-01-29 | Mcneil Pharmaceutical | Hexahydropyrrolo(2,1-a)isoquinoline derivatives |
GB2271566A (en) * | 1992-10-14 | 1994-04-20 | Merck & Co Inc | HIV integrase inhibitors |
US7163949B1 (en) * | 1999-11-03 | 2007-01-16 | Amr Technology, Inc. | 4-phenyl substituted tetrahydroisoquinolines and use thereof |
JP4907818B2 (ja) * | 1999-11-03 | 2012-04-04 | エーエムアール テクノロジー インコーポレイテッド | アリールおよびヘテロアリール置換テトラヒドロイソキノリン、ならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを阻止するためのそれらの使用 |
RU2293728C2 (ru) * | 1999-11-03 | 2007-02-20 | Эймр Текнолоджи, Инк. | Производные тетрагидроизохинолина, содержащая их фармацевтическая композиция, способ ингибирования синаптического захвата допамина и способ лечения |
EP1113007A1 (en) * | 1999-12-24 | 2001-07-04 | Pfizer Inc. | Tetrahydroisoquinoline compounds as estrogen agonists/antagonists |
WO2002004455A2 (en) * | 2000-07-11 | 2002-01-17 | Albany Molecular Research, Inc | 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof |
ZA200701232B (en) | 2004-07-15 | 2008-08-27 | Amr Technology Inc | Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
US7417054B2 (en) | 2005-06-17 | 2008-08-26 | Janssen Pharmaceutica N.V. | Naphthyridine compounds |
EA019115B1 (ru) | 2005-07-15 | 2014-01-30 | Олбани Молекьюлар Рисерч, Инк. | Арил- и гетероарилзамещенные тетрагидробензазепины и их применение для блокировки обратного захвата норэпинефрина, допамина и серотонина |
AR071997A1 (es) | 2008-06-04 | 2010-07-28 | Bristol Myers Squibb Co | Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina |
US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
AU2010247763B2 (en) | 2009-05-12 | 2015-12-24 | Albany Molecular Research, Inc. | 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof |
MX2011011901A (es) | 2009-05-12 | 2012-01-20 | Albany Molecular Res Inc | Tetrahidroisoquinolinas aril, heteroaril, y heterociclo sustituidas y uso de las mismas. |
AU2010247735B2 (en) | 2009-05-12 | 2015-07-16 | Albany Molecular Research, Inc. | Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670694B2 (de) * | 1966-05-05 | 1976-07-22 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von tetrahydroisochinolinen |
-
1970
- 1970-01-06 CH CH10370A patent/CH527194A/de not_active IP Right Cessation
- 1970-01-06 CH CH1011872A patent/CH538477A/de not_active IP Right Cessation
- 1970-12-16 DE DE2062001A patent/DE2062001C2/de not_active Expired
- 1970-12-16 SE SE7313623A patent/SE386672B/sv unknown
- 1970-12-16 SE SE17063/70A patent/SE368401B/xx unknown
- 1970-12-21 ZA ZA708590A patent/ZA708590B/xx unknown
- 1970-12-28 IL IL35916A patent/IL35916A/xx unknown
- 1970-12-29 NL NLAANVRAGE7018956,A patent/NL171444C/xx not_active IP Right Cessation
- 1970-12-31 FI FI703519A patent/FI49503C/sv active
-
1971
- 1971-01-04 IE IE6/71A patent/IE34859B1/xx unknown
- 1971-01-05 BE BE761219A patent/BE761219A/xx not_active IP Right Cessation
- 1971-01-05 AT AT4571A patent/AT303041B/de not_active IP Right Cessation
- 1971-01-05 ES ES387016A patent/ES387016A1/es not_active Expired
- 1971-01-05 GB GB45471A patent/GB1335261A/en not_active Expired
- 1971-01-05 NO NO7121A patent/NO135315C/no unknown
- 1971-01-05 DK DK2571AA patent/DK125021B/da not_active IP Right Cessation
- 1971-01-05 FR FR7100097A patent/FR2081412B1/fr not_active Expired
- 1971-01-06 CA CA102,060A patent/CA999866A/en not_active Expired
- 1971-01-06 JP JP7194A patent/JPS5515476B1/ja active Pending
- 1971-01-06 YU YU19/71A patent/YU33660B/xx unknown
- 1971-01-07 PH PH12087*UA patent/PH9682A/en unknown
-
1973
- 1973-10-05 SE SE7313622A patent/SE399879B/sv unknown
Also Published As
Publication number | Publication date |
---|---|
YU33660B (en) | 1977-12-31 |
IE34859L (en) | 1971-07-06 |
GB1335261A (en) | 1973-10-24 |
BE761219A (fr) | 1971-07-05 |
DE2062001A1 (de) | 1971-07-15 |
IE34859B1 (en) | 1975-09-03 |
CH527194A (de) | 1972-08-31 |
AT303041B (de) | 1972-11-10 |
FR2081412B1 (sv) | 1974-04-12 |
NL171444C (nl) | 1983-04-05 |
CA999866A (en) | 1976-11-16 |
FI49503C (sv) | 1975-07-10 |
NO135315B (sv) | 1976-12-13 |
DE2062001C2 (de) | 1986-10-16 |
IL35916A (en) | 1973-11-28 |
NL171444B (nl) | 1982-11-01 |
IL35916A0 (en) | 1971-02-25 |
ZA708590B (en) | 1971-09-29 |
PH9682A (en) | 1976-02-10 |
DK125021B (da) | 1972-12-18 |
SE386672B (sv) | 1976-08-16 |
NL7018956A (sv) | 1971-07-08 |
ES387016A1 (es) | 1976-05-01 |
JPS5515476B1 (sv) | 1980-04-23 |
FI49503B (sv) | 1975-04-01 |
FR2081412A1 (sv) | 1971-12-03 |
CH538477A (de) | 1973-06-30 |
YU1971A (en) | 1977-06-30 |
SE368401B (sv) | 1974-07-01 |
NO135315C (sv) | 1977-03-23 |
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