SE0301998D0 - Quil A fraction with low toxicity and use thereof - Google Patents
Quil A fraction with low toxicity and use thereofInfo
- Publication number
- SE0301998D0 SE0301998D0 SE0301998A SE0301998A SE0301998D0 SE 0301998 D0 SE0301998 D0 SE 0301998D0 SE 0301998 A SE0301998 A SE 0301998A SE 0301998 A SE0301998 A SE 0301998A SE 0301998 D0 SE0301998 D0 SE 0301998D0
- Authority
- SE
- Sweden
- Prior art keywords
- quil
- fraction
- adjuvant
- lps
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301998A SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Quil A fraction with low toxicity and use thereof |
PCT/SE2004/001038 WO2005002620A1 (en) | 2003-07-07 | 2004-07-07 | Quil a fraction with low toxicity and use thereof |
PL04749076T PL1648505T3 (pl) | 2003-07-07 | 2004-07-07 | Frakcja Quil A o niskiej toksyczności i jej zastosowanie |
US10/562,866 US8821881B2 (en) | 2003-07-07 | 2004-07-07 | Quil A fraction with low toxicity and use thereof |
AT04749076T ATE442164T1 (de) | 2003-07-07 | 2004-07-07 | Quil a fraktion mit geringer toxizität und ihre verwendung |
NZ544299A NZ544299A (en) | 2003-07-07 | 2004-07-07 | Quil A fraction A for the enhancement of immune activities and immunomodulating activities |
AU2004254152A AU2004254152B2 (en) | 2003-07-07 | 2004-07-07 | Quil a fraction with low toxicity and use thereof |
BRPI0412444A BRPI0412444B8 (pt) | 2003-07-07 | 2004-07-07 | fração de quil a com baixa toxidez e seu uso |
JP2006518582A JP4731475B2 (ja) | 2003-07-07 | 2004-07-07 | 毒性の低いQuilA画分およびその使用 |
ES04749076T ES2331952T3 (es) | 2003-07-07 | 2004-07-07 | Fraccion de quil a con baja toxicidad y su uso. |
DE602004023089T DE602004023089D1 (de) | 2003-07-07 | 2004-07-07 | Quil a fraktion mit geringer toxizität und ihre verwendung |
DK04749076T DK1648505T3 (da) | 2003-07-07 | 2004-07-07 | Quil A-fraktion med lav toksicitet og anvendelse deraf |
EP04749076A EP1648505B1 (en) | 2003-07-07 | 2004-07-07 | Quil a fraction with low toxicity and use thereof |
CA2529363A CA2529363C (en) | 2003-07-07 | 2004-07-07 | Quil a fraction with low toxicity and use thereof |
ZA200600151A ZA200600151B (en) | 2003-07-07 | 2006-01-06 | Quil A fraction with low toxicity and use thereof |
US14/445,690 US20140335049A1 (en) | 2003-07-07 | 2014-07-29 | Quil a fraction with low toxicity and use thereof |
US14/714,664 US20150320858A1 (en) | 2003-07-07 | 2015-05-18 | Quil a fraction with low toxicity and use thereof |
US15/054,801 US20160184427A1 (en) | 2003-07-07 | 2016-02-26 | Quil a fraction with low toxicity and use thereof |
US15/874,262 US20180369368A1 (en) | 2003-07-07 | 2018-01-18 | Quil a fraction with low toxicity and use thereof |
US16/701,948 US20200345840A1 (en) | 2003-07-07 | 2019-12-03 | Quil a fraction with low toxicity and use thereof |
US17/477,739 US20220241408A1 (en) | 2003-07-07 | 2021-09-17 | Quil a fraction with low toxicity and use thereof |
US18/376,666 US20240024468A1 (en) | 2003-07-07 | 2023-10-04 | Quil a fraction with low toxicity and use thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301998A SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Quil A fraction with low toxicity and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0301998D0 true SE0301998D0 (sv) | 2003-07-07 |
Family
ID=27731119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0301998A SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Quil A fraction with low toxicity and use thereof |
Country Status (15)
Country | Link |
---|---|
US (8) | US8821881B2 (sv) |
EP (1) | EP1648505B1 (sv) |
JP (1) | JP4731475B2 (sv) |
AT (1) | ATE442164T1 (sv) |
AU (1) | AU2004254152B2 (sv) |
BR (1) | BRPI0412444B8 (sv) |
CA (1) | CA2529363C (sv) |
DE (1) | DE602004023089D1 (sv) |
DK (1) | DK1648505T3 (sv) |
ES (1) | ES2331952T3 (sv) |
NZ (1) | NZ544299A (sv) |
PL (1) | PL1648505T3 (sv) |
SE (1) | SE0301998D0 (sv) |
WO (1) | WO2005002620A1 (sv) |
ZA (1) | ZA200600151B (sv) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
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DK1104306T3 (da) * | 1998-08-10 | 2006-05-22 | Antigenics Inc | Præparater af CpG- og saponinadjuvanser og fremgangsmåder til anvendelse deraf |
SE0202110D0 (sv) * | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
SE0301998D0 (sv) * | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
BRPI0606481A2 (pt) * | 2005-01-20 | 2009-06-30 | Isconova Ab | composição de vacina compreendendo uma proteìna de ligação a fibronectina ou um peptìdeo de ligação a fibronectina |
EP1764369A1 (de) | 2005-09-16 | 2007-03-21 | Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH | Vakzine enthaltend trunkiertes HBV core protein plus Saponin-basierendes Adjuvants |
AU2007231027B2 (en) | 2006-03-24 | 2013-10-03 | Novartis Influenza Vaccines Marburg Gmbh | Storage of influenza vaccines without refrigeration |
DK2054431T3 (da) | 2006-06-09 | 2012-01-02 | Novartis Ag | Konformere af bakterielle adhæsiner |
EP1902727A1 (de) * | 2006-09-22 | 2008-03-26 | Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH | Vakzine enthaltend trunkiertes HBV core protein plus Saponin-basierendes Adjuvants |
WO2008031878A1 (en) * | 2006-09-15 | 2008-03-20 | Rhein Biotech Gesellschaft für neue Biotechnologische Prozesse und Produkte mbH | A composition for therapy and/or for prophylaxis of hbv-infections and hbv-mediated diseases |
CN101563090B (zh) * | 2006-11-20 | 2013-01-02 | 杜科姆公司 | 包含南美皂皮树皂苷的含脂质颗粒用于治疗癌症的用途 |
CN101784283A (zh) | 2007-06-27 | 2010-07-21 | 诺华有限公司 | 低添加流感疫苗 |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
EP3552625A1 (en) * | 2008-06-27 | 2019-10-16 | Zoetis Services LLC | Novel adjuvant compositions |
WO2011005183A1 (en) * | 2009-07-10 | 2011-01-13 | Isconova Ab | New composition |
CA2808556A1 (en) | 2010-09-20 | 2012-03-29 | Crucell Holland B.V. | Therapeutic vaccination against active tuberculosis |
AU2012319239B2 (en) | 2011-10-03 | 2017-04-20 | Mx Adjuvac Ab | Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds |
US9452211B2 (en) | 2011-11-28 | 2016-09-27 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
HUE027839T2 (en) | 2012-03-12 | 2016-11-28 | Crucell Holland Bv | Recombinant adenoviruses with altered terminals |
US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
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ES2959258T3 (es) | 2013-02-07 | 2024-02-22 | Childrens Medical Center | Antígenos proteicos que proporcionan protección contra la colonización y/o la enfermedad neumocócicas |
JP6282673B2 (ja) | 2013-03-08 | 2018-02-21 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 無細胞百日咳ワクチン |
US9907846B2 (en) | 2013-04-01 | 2018-03-06 | Mx Adjuvac Ab | Nanoparticles, composed of sterol and saponin from Quillaja saponaria Molina for use in pharmaceutical compositions |
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WO2015000832A1 (en) | 2013-07-02 | 2015-01-08 | Crucell Holland B.V. | Method for preparing virosomes |
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NZ733383A (en) | 2013-09-19 | 2022-12-23 | Zoetis Services Llc | Oil-based adjuvants |
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DE202016003070U1 (de) | 2016-05-09 | 2016-06-07 | Clariant International Ltd. | Stabilisatoren für Silikatfarben |
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KR20230147156A (ko) | 2021-02-19 | 2023-10-20 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 융합 전 rsv fb 항원 |
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ATE71303T1 (de) * | 1986-01-14 | 1992-01-15 | Nederlanden Staat | Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung. |
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NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
NL9002314A (nl) * | 1990-10-23 | 1992-05-18 | Nederlanden Staat | Immunogene complexen, in het bijzonder iscoms. |
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SE0202110D0 (sv) * | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
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2003
- 2003-07-07 SE SE0301998A patent/SE0301998D0/sv unknown
-
2004
- 2004-07-07 AT AT04749076T patent/ATE442164T1/de not_active IP Right Cessation
- 2004-07-07 US US10/562,866 patent/US8821881B2/en active Active
- 2004-07-07 DK DK04749076T patent/DK1648505T3/da active
- 2004-07-07 DE DE602004023089T patent/DE602004023089D1/de not_active Expired - Lifetime
- 2004-07-07 WO PCT/SE2004/001038 patent/WO2005002620A1/en active Application Filing
- 2004-07-07 JP JP2006518582A patent/JP4731475B2/ja not_active Expired - Lifetime
- 2004-07-07 AU AU2004254152A patent/AU2004254152B2/en not_active Expired
- 2004-07-07 BR BRPI0412444A patent/BRPI0412444B8/pt active IP Right Grant
- 2004-07-07 ES ES04749076T patent/ES2331952T3/es not_active Expired - Lifetime
- 2004-07-07 CA CA2529363A patent/CA2529363C/en not_active Expired - Lifetime
- 2004-07-07 NZ NZ544299A patent/NZ544299A/en not_active IP Right Cessation
- 2004-07-07 EP EP04749076A patent/EP1648505B1/en not_active Expired - Lifetime
- 2004-07-07 PL PL04749076T patent/PL1648505T3/pl unknown
-
2006
- 2006-01-06 ZA ZA200600151A patent/ZA200600151B/en unknown
-
2014
- 2014-07-29 US US14/445,690 patent/US20140335049A1/en not_active Abandoned
-
2015
- 2015-05-18 US US14/714,664 patent/US20150320858A1/en not_active Abandoned
-
2016
- 2016-02-26 US US15/054,801 patent/US20160184427A1/en not_active Abandoned
-
2018
- 2018-01-18 US US15/874,262 patent/US20180369368A1/en not_active Abandoned
-
2019
- 2019-12-03 US US16/701,948 patent/US20200345840A1/en not_active Abandoned
-
2021
- 2021-09-17 US US17/477,739 patent/US20220241408A1/en not_active Abandoned
-
2023
- 2023-10-04 US US18/376,666 patent/US20240024468A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20060239963A1 (en) | 2006-10-26 |
ATE442164T1 (de) | 2009-09-15 |
US20200345840A1 (en) | 2020-11-05 |
CA2529363A1 (en) | 2005-01-13 |
PL1648505T3 (pl) | 2010-02-26 |
JP2007527386A (ja) | 2007-09-27 |
US20180369368A1 (en) | 2018-12-27 |
AU2004254152B2 (en) | 2009-10-29 |
BRPI0412444B8 (pt) | 2021-05-25 |
US20160184427A1 (en) | 2016-06-30 |
CA2529363C (en) | 2013-04-02 |
AU2004254152A1 (en) | 2005-01-13 |
WO2005002620A1 (en) | 2005-01-13 |
ES2331952T3 (es) | 2010-01-21 |
BRPI0412444A (pt) | 2006-09-19 |
US20220241408A1 (en) | 2022-08-04 |
ZA200600151B (en) | 2007-01-31 |
US20140335049A1 (en) | 2014-11-13 |
DK1648505T3 (da) | 2009-12-21 |
BRPI0412444B1 (pt) | 2016-06-14 |
US20240024468A1 (en) | 2024-01-25 |
DE602004023089D1 (de) | 2009-10-22 |
US20150320858A1 (en) | 2015-11-12 |
EP1648505A1 (en) | 2006-04-26 |
EP1648505B1 (en) | 2009-09-09 |
US8821881B2 (en) | 2014-09-02 |
NZ544299A (en) | 2009-03-31 |
JP4731475B2 (ja) | 2011-07-27 |
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