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SE0101769D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0101769D0
SE0101769D0 SE0101769A SE0101769A SE0101769D0 SE 0101769 D0 SE0101769 D0 SE 0101769D0 SE 0101769 A SE0101769 A SE 0101769A SE 0101769 A SE0101769 A SE 0101769A SE 0101769 D0 SE0101769 D0 SE 0101769D0
Authority
SE
Sweden
Prior art keywords
sub
ring
phenyl
novel compounds
compounds
Prior art date
Application number
SE0101769A
Other languages
English (en)
Inventor
William Brown
Andrew Griffin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101769A priority Critical patent/SE0101769D0/sv
Publication of SE0101769D0 publication Critical patent/SE0101769D0/sv
Priority to KR10-2003-7014946A priority patent/KR20030094425A/ko
Priority to PL02366387A priority patent/PL366387A1/xx
Priority to NZ529398A priority patent/NZ529398A/en
Priority to PCT/SE2002/000944 priority patent/WO2002094782A1/en
Priority to EEP200300554A priority patent/EE200300554A/xx
Priority to JP2002591455A priority patent/JP2005508289A/ja
Priority to BR0209670-6A priority patent/BR0209670A/pt
Priority to HU0401328A priority patent/HUP0401328A2/hu
Priority to RU2003131966/04A priority patent/RU2003131966A/ru
Priority to AT02733702T priority patent/ATE313528T1/de
Priority to DE60208192T priority patent/DE60208192T2/de
Priority to MXPA03010440A priority patent/MXPA03010440A/es
Priority to CZ20033089A priority patent/CZ20033089A3/cs
Priority to CA002446311A priority patent/CA2446311A1/en
Priority to CNA028141601A priority patent/CN1639123A/zh
Priority to IL15862802A priority patent/IL158628A0/xx
Priority to ARP020101814A priority patent/AR033758A1/es
Priority to SK1391-2003A priority patent/SK13912003A3/sk
Priority to EP02733702A priority patent/EP1395555B1/en
Priority to US10/477,852 priority patent/US7226933B2/en
Priority to ZA200308631A priority patent/ZA200308631B/xx
Priority to BG108330A priority patent/BG108330A/bg
Priority to CO03100165A priority patent/CO5540317A2/es
Priority to IS7028A priority patent/IS7028A/is
Priority to NO20035113A priority patent/NO20035113D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE0101769A 2001-05-18 2001-05-18 Novel compounds SE0101769D0 (sv)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SE0101769A SE0101769D0 (sv) 2001-05-18 2001-05-18 Novel compounds
US10/477,852 US7226933B2 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
MXPA03010440A MXPA03010440A (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)amino)-benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales.
CA002446311A CA2446311A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
NZ529398A NZ529398A (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives as opiod receptor agonists and their use for the treatment of pain, anxiety or gastrointestinal disorders
PCT/SE2002/000944 WO2002094782A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
EEP200300554A EE200300554A (et) 2001-05-18 2002-05-16 4-(fenüül(piperidiin-4-üül)amino)bensamiidi derivaadid, nende valmistamine ja kasutamine valu, ärevuse või seedetrakti häirete ravis
JP2002591455A JP2005508289A (ja) 2001-05-18 2002-05-16 4−(フェニル−(ピペリジン−4−イル)−アミノ)−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
BR0209670-6A BR0209670A (pt) 2001-05-18 2002-05-16 Composto, processo para preparar e uso do mesmo, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais e da ansiedade
HU0401328A HUP0401328A2 (hu) 2001-05-18 2002-05-16 4-[Fenil-(4-piperidinil)-amino]-benzamid-származékok, alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
RU2003131966/04A RU2003131966A (ru) 2001-05-18 2002-05-16 Производные 4-(фенил-(пиперидин-4-ил)-амино)-бензамида и их применение для лечения боли, тревоги или желудочно-кишечных расстройств
AT02733702T ATE313528T1 (de) 2001-05-18 2002-05-16 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen
DE60208192T DE60208192T2 (de) 2001-05-18 2002-05-16 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
KR10-2003-7014946A KR20030094425A (ko) 2001-05-18 2002-05-16 4-(페닐-(피페리딘-4-일)-아미노)-벤즈아미드 유도체 및통증, 불안증 또는 위장관 장애의 치료를 위한 그의 용도
CZ20033089A CZ20033089A3 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
PL02366387A PL366387A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
CNA028141601A CN1639123A (zh) 2001-05-18 2002-05-16 4-(苯基-(哌啶-4-基)-氨基)-苯甲酰胺衍生物及其在治疗疼痛、焦虑症或胃肠道疾病中的应用
IL15862802A IL158628A0 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
ARP020101814A AR033758A1 (es) 2001-05-18 2002-05-16 Compuestos 4-(fenil-(piperidinil-4-il)amino)benzamida
SK1391-2003A SK13912003A3 (sk) 2001-05-18 2002-05-16 4-(Fenyl(piperidin-4-yl)amino)benzamidové deriváty a ich požitie na liečbu bolesti, anxiety alebo gastrointestinálnych porúch
EP02733702A EP1395555B1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
ZA200308631A ZA200308631B (en) 2001-05-18 2003-11-05 4-(Phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders.
BG108330A BG108330A (bg) 2001-05-18 2003-11-07 4-(фенил-(пиперидин-4-ил)-амино)-бензамидни производни и тяхното използване за лечение на болка, потиснатост или стомашно-чревни разстройства
CO03100165A CO5540317A2 (es) 2001-05-18 2003-11-12 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinales
IS7028A IS7028A (is) 2001-05-18 2003-11-12 4-(fenýl-(píperidín-4-ýl)-amínó)-bensamíðafleiðurog notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum
NO20035113A NO20035113D0 (no) 2001-05-18 2003-11-17 4-(fenyl-(piperidin-4-yl)-amino)-benzamidderivater og deres anvendelse vedbehandling av angst, smerte eller gastrointestinale forstyrrelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101769A SE0101769D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Publications (1)

Publication Number Publication Date
SE0101769D0 true SE0101769D0 (sv) 2001-05-18

Family

ID=20284172

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101769A SE0101769D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Country Status (26)

Country Link
US (1) US7226933B2 (sv)
EP (1) EP1395555B1 (sv)
JP (1) JP2005508289A (sv)
KR (1) KR20030094425A (sv)
CN (1) CN1639123A (sv)
AR (1) AR033758A1 (sv)
AT (1) ATE313528T1 (sv)
BG (1) BG108330A (sv)
BR (1) BR0209670A (sv)
CA (1) CA2446311A1 (sv)
CO (1) CO5540317A2 (sv)
CZ (1) CZ20033089A3 (sv)
DE (1) DE60208192T2 (sv)
EE (1) EE200300554A (sv)
HU (1) HUP0401328A2 (sv)
IL (1) IL158628A0 (sv)
IS (1) IS7028A (sv)
MX (1) MXPA03010440A (sv)
NO (1) NO20035113D0 (sv)
NZ (1) NZ529398A (sv)
PL (1) PL366387A1 (sv)
RU (1) RU2003131966A (sv)
SE (1) SE0101769D0 (sv)
SK (1) SK13912003A3 (sv)
WO (1) WO2002094782A1 (sv)
ZA (1) ZA200308631B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0308081A (pt) * 2002-03-13 2004-12-21 Janssen Pharmaceutica Nv Inibidores de histona desacetilase
SE0300987D0 (sv) * 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
EP1675847B1 (en) 2003-10-01 2012-12-05 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) * 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
JP2010503669A (ja) * 2006-09-12 2010-02-04 アドラー コーポレーション 認知機能の強化のためのn含有スピロ化合物の使用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091096A (en) * 1976-03-19 1978-05-23 Eli Lilly And Company Dinitroanilines for the control of phytopathogens
EG12406A (en) * 1976-08-12 1979-03-31 Janssen Pharmaceutica Nv Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
US4252812A (en) * 1977-05-23 1981-02-24 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
SE441448B (sv) 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3563964D1 (en) * 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
WO1999033806A1 (en) 1997-12-24 1999-07-08 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
WO1999045925A1 (en) 1998-03-10 1999-09-16 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
BR0108965A (pt) * 2000-03-03 2002-11-26 Ortho Mcneil Pharm Inc Derivados de 3-(diarilmetileno)-8-azabiciclo[3,2,1]octano
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
JPWO2009028275A1 (ja) * 2007-08-28 2010-11-25 コニカミノルタエムジー株式会社 シンチレータパネル

Also Published As

Publication number Publication date
EE200300554A (et) 2004-02-16
JP2005508289A (ja) 2005-03-31
ZA200308631B (en) 2005-02-07
NO20035113D0 (no) 2003-11-17
MXPA03010440A (es) 2004-03-09
CO5540317A2 (es) 2005-07-29
HUP0401328A2 (hu) 2004-12-28
DE60208192T2 (de) 2006-07-13
KR20030094425A (ko) 2003-12-11
WO2002094782A1 (en) 2002-11-28
CZ20033089A3 (en) 2004-06-16
PL366387A1 (en) 2005-01-24
RU2003131966A (ru) 2005-05-10
SK13912003A3 (sk) 2004-04-06
ATE313528T1 (de) 2006-01-15
IS7028A (is) 2003-11-12
BG108330A (bg) 2004-12-30
US20040235897A1 (en) 2004-11-25
AR033758A1 (es) 2004-01-07
NZ529398A (en) 2005-08-26
US7226933B2 (en) 2007-06-05
CA2446311A1 (en) 2002-11-28
BR0209670A (pt) 2004-04-20
CN1639123A (zh) 2005-07-13
DE60208192D1 (de) 2006-01-26
IL158628A0 (en) 2004-05-12
EP1395555B1 (en) 2005-12-21
EP1395555A1 (en) 2004-03-10

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