RU98107447A - ANTI-INFLAMMATORY AND ANTIMICROBIC MEDICINE FOR LOCAL USE - Google Patents
ANTI-INFLAMMATORY AND ANTIMICROBIC MEDICINE FOR LOCAL USEInfo
- Publication number
- RU98107447A RU98107447A RU98107447/14A RU98107447A RU98107447A RU 98107447 A RU98107447 A RU 98107447A RU 98107447/14 A RU98107447/14 A RU 98107447/14A RU 98107447 A RU98107447 A RU 98107447A RU 98107447 A RU98107447 A RU 98107447A
- Authority
- RU
- Russia
- Prior art keywords
- inflammatory
- antimicrobic
- medicine
- miramistin
- cyclodextrin
- Prior art date
Links
- 230000003110 anti-inflammatory Effects 0.000 title 1
- 230000003377 anti-microbal Effects 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 claims 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 4
- 239000003470 adrenal cortex hormone Substances 0.000 claims 3
- 229960001927 Cetylpyridinium Chloride Drugs 0.000 claims 2
- YMKDRGPMQRFJGP-UHFFFAOYSA-M Cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 claims 2
- 229920000858 Cyclodextrin Polymers 0.000 claims 2
- 239000001116 FEMA 4028 Substances 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- JQQZCIIDNVIQKO-UHFFFAOYSA-N benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC1=CC=CC=C1 JQQZCIIDNVIQKO-UHFFFAOYSA-N 0.000 claims 2
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims 2
- 229960004853 betadex Drugs 0.000 claims 2
- 229940082500 cetostearyl alcohol Drugs 0.000 claims 2
- 230000000699 topical Effects 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N β-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 2
- UREBDLICKHMUKA-DVTGEIKXSA-N Betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
- 229960003957 Dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N Dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960001347 Fluocinolone Acetonide Drugs 0.000 claims 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N Fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 1
- 229960003973 Fluocortolone Drugs 0.000 claims 1
- GAKMQHDJQHZUTJ-ULHLPKEOSA-N Fluocortolone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@@H](C)[C@H](C(=O)CO)[C@@]2(C)C[C@@H]1O GAKMQHDJQHZUTJ-ULHLPKEOSA-N 0.000 claims 1
- 229960002117 Triamcinolone Acetonide Drugs 0.000 claims 1
- YNDXUCZADRHECN-JNQJZLCISA-N Triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 229960002537 betamethasone Drugs 0.000 claims 1
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- 229950009938 flumetasone pivalate Drugs 0.000 claims 1
- JWRMHDSINXPDHB-OJAGFMMFSA-N flumethasone pivalate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)COC(=O)C(C)(C)C)(O)[C@@]2(C)C[C@@H]1O JWRMHDSINXPDHB-OJAGFMMFSA-N 0.000 claims 1
- 229940042902 flumethasone pivalate Drugs 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000003883 ointment base Substances 0.000 claims 1
- 239000008213 purified water Substances 0.000 claims 1
Claims (1)
Фторированный кортикостероид - 0,01 - 1,00
Мирамистин или цетилпиридиний хлорид - 0,10 - 1,00
Пропиленгликоль - 10,00 - 46,00
β-циклодекстрин - 0,40 - 2,40
Спирты синтетические высшие жирные фракций C16-C20 или цетостеариловый спирт - 0,50 - 8,50
Вода очищенная - Остальное
2. Противовоспалительное и антимикробное лекарственное средство для местного применения по п.1, отличающееся тем, что фторированный кортикостероид выбирают из ряда триамцинолона ацетонид, бетаметазон, флюоцинолона ацетонид, флюметазона пивалат, флюокортолон, дексаметазон.1. An anti-inflammatory and antimicrobial drug for topical use, containing a fluorinated corticosteroid and an ointment-based antimicrobial agent, characterized in that miramistin or cetylpyridinium chloride is used as an antimicrobial agent, and the ointment base contains propylene glycol, β-cyclodextrin, higher synthetic fatty alcohols C 16 -C 20 or cetostearyl alcohol and water purified in the following ratio of components, wt.%:
Fluorinated corticosteroid - 0.01 - 1.00
Miramistin or cetylpyridinium chloride - 0.10 - 1.00
Propylene glycol - 10.00 - 46.00
β-cyclodextrin - 0.40 - 2.40
Alcohols synthetic higher fatty fractions C 16 -C 20 or cetostearyl alcohol - 0.50 - 8.50
Purified Water - Else
2. The anti-inflammatory and antimicrobial drug for topical use according to claim 1, characterized in that the fluorinated corticosteroid is selected from the range of triamcinolone acetonide, betamethasone, fluocinolone acetonide, flumethasone pivalate, fluocortolone, dexamethasone.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU98107447/14A RU2157214C2 (en) | 1998-04-16 | 1998-04-16 | Anti-inflammatory and antibacterial drug for topical use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU98107447/14A RU2157214C2 (en) | 1998-04-16 | 1998-04-16 | Anti-inflammatory and antibacterial drug for topical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU98107447A true RU98107447A (en) | 2000-01-27 |
| RU2157214C2 RU2157214C2 (en) | 2000-10-10 |
Family
ID=20205000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU98107447/14A RU2157214C2 (en) | 1998-04-16 | 1998-04-16 | Anti-inflammatory and antibacterial drug for topical use |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2157214C2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2161961C1 (en) * | 2000-03-17 | 2001-01-20 | Кривошеин Юрий Семенович | Therapeutic preparation |
| WO2004069280A1 (en) * | 2003-02-06 | 2004-08-19 | Cipla Ltd | Pharmaceutical inclusion complexes containing a steroid and optionally an antibacterial agent |
| US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| WO2011100994A1 (en) * | 2010-02-19 | 2011-08-25 | Megainpharm Gmbh | Pharmaceutical comprising myramistin |
| RU2014129362A (en) * | 2012-11-12 | 2016-02-10 | Виктор Станиславович Поляков | Dermatological composition with indicator properties |
| CN105106234A (en) * | 2015-09-28 | 2015-12-02 | 兰晶 | Anti-allergy and anti-inflammatory external preparation special for treatment of allergic dermatitis |
-
1998
- 1998-04-16 RU RU98107447/14A patent/RU2157214C2/en not_active IP Right Cessation
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