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JPS5524131A - Synthetic adrenal cortical hormone preparation ointment and its base - Google Patents

Synthetic adrenal cortical hormone preparation ointment and its base

Info

Publication number
JPS5524131A
JPS5524131A JP9698678A JP9698678A JPS5524131A JP S5524131 A JPS5524131 A JP S5524131A JP 9698678 A JP9698678 A JP 9698678A JP 9698678 A JP9698678 A JP 9698678A JP S5524131 A JPS5524131 A JP S5524131A
Authority
JP
Japan
Prior art keywords
ointment
base
adrenal cortical
propylene carbonate
hormone preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9698678A
Other languages
Japanese (ja)
Other versions
JPS5728692B2 (en
Inventor
Yoshiaki Inoue
Ikuo Kishi
Tateaki Miyaji
Toshio Kumagai
Emu Kudora Ronarudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON REDARII KK
Pfizer Japan Inc
Original Assignee
NIPPON REDARII KK
Lederle Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIPPON REDARII KK, Lederle Japan Ltd filed Critical NIPPON REDARII KK
Priority to JP9698678A priority Critical patent/JPS5524131A/en
Publication of JPS5524131A publication Critical patent/JPS5524131A/en
Publication of JPS5728692B2 publication Critical patent/JPS5728692B2/ja
Granted legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: The title stable ointment having improved clinical anti-inflammatory action, comprising Amcinonide as an active constituent and propylene carbonate as its solubilizer.
CONSTITUTION: An ointment comprising (A) Amcinonide (chemical name; 16α, 17α-cyclopentylidenedioxy-9α-fluoro-11β, 21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate) as an active constituent, (B) propylene carbonate as a solubilizer, and (C) an ointment constituent, e.g. wax or Vaselin, which is pharmaceutically acceptable. Preferably, tocopherol is used as antioxidant. The propylene carbonate greatly inhibits or suppresses the decomposition of (A).
COPYRIGHT: (C)1980,JPO&Japio
JP9698678A 1978-08-09 1978-08-09 Synthetic adrenal cortical hormone preparation ointment and its base Granted JPS5524131A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9698678A JPS5524131A (en) 1978-08-09 1978-08-09 Synthetic adrenal cortical hormone preparation ointment and its base

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9698678A JPS5524131A (en) 1978-08-09 1978-08-09 Synthetic adrenal cortical hormone preparation ointment and its base

Publications (2)

Publication Number Publication Date
JPS5524131A true JPS5524131A (en) 1980-02-21
JPS5728692B2 JPS5728692B2 (en) 1982-06-18

Family

ID=14179527

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9698678A Granted JPS5524131A (en) 1978-08-09 1978-08-09 Synthetic adrenal cortical hormone preparation ointment and its base

Country Status (1)

Country Link
JP (1) JPS5524131A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000041702A1 (en) * 1999-01-13 2000-07-20 Taisho Pharmaceutical Co., Ltd. External steroid preparation
JP2008522997A (en) * 2004-12-09 2008-07-03 バイエル・ヘルスケア・アクチェンゲゼルシャフト Stabilization of glucocorticoid esters by acid.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000041702A1 (en) * 1999-01-13 2000-07-20 Taisho Pharmaceutical Co., Ltd. External steroid preparation
JP2008522997A (en) * 2004-12-09 2008-07-03 バイエル・ヘルスケア・アクチェンゲゼルシャフト Stabilization of glucocorticoid esters by acid.

Also Published As

Publication number Publication date
JPS5728692B2 (en) 1982-06-18

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