RO83468B - Procedeu de obtinere a derivatilor de 5, 6, 7, 7a-tetrahidro-4h-tieno(3, 2-c)-piridin-2-onei - Google Patents
Procedeu de obtinere a derivatilor de 5, 6, 7, 7a-tetrahidro-4h-tieno(3, 2-c)-piridin-2-oneiInfo
- Publication number
- RO83468B RO83468B RO105884A RO10588481A RO83468B RO 83468 B RO83468 B RO 83468B RO 105884 A RO105884 A RO 105884A RO 10588481 A RO10588481 A RO 10588481A RO 83468 B RO83468 B RO 83468B
- Authority
- RO
- Romania
- Prior art keywords
- lower alkyl
- tetrahydro
- derivatives
- hydrogen atom
- radical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Inventia se refera la un procedeu de preparare a derivatilor de 5,6,7,7a-tetrahidro-4H-/3,2a/piridin-2-ona cu formula generala I: (vezi formula) în care R reprezinta un atom de hidrogen sau un radical fenil, eventual substituit cu un atom de halogen sau un radical alchil inferior, alcoxi inferior, nitro, carboxi, alcoxi carbonil sau cian, R' reprezinta un atom de hidrogen, un radical alchil inferior, n este zero sau un numar întreg cuprins între 1...4, care are un compus cu formula generala II:(vezi formula) în care R, R' si n au semnificatiile de mai sus si R'' reprezinta un atom de hidrogen sau un radical alchil inferior, se supune reactiei cu acid clorhidric gazos si cu hidrogen sulfurat gazos succesiv sau în amestec, în mediu de alcool inferior sau amestecurile acestora, la o temperatura cuprinsa între temperatura camerei si punctul de fierbere al solventului.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8025275A FR2495157A1 (fr) | 1980-11-28 | 1980-11-28 | Procede nouveau de preparation des tetrahydro-5, 6, 7, 7a 4h-thieno (3, 2-c) pyridinones-2 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO83468A RO83468A (ro) | 1984-04-02 |
| RO83468B true RO83468B (ro) | 1984-04-30 |
Family
ID=9248449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO105884A RO83468B (ro) | 1980-11-28 | 1981-11-27 | Procedeu de obtinere a derivatilor de 5, 6, 7, 7a-tetrahidro-4h-tieno(3, 2-c)-piridin-2-onei |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US4424356A (ro) |
| EP (1) | EP0053949B1 (ro) |
| KR (1) | KR870000823B1 (ro) |
| AR (1) | AR228166A1 (ro) |
| AT (1) | ATE5725T1 (ro) |
| AU (1) | AU543463B2 (ro) |
| BG (1) | BG36347A3 (ro) |
| CA (1) | CA1182116A (ro) |
| CS (1) | CS224635B2 (ro) |
| CY (1) | CY1280A (ro) |
| DD (1) | DD201798A5 (ro) |
| DE (1) | DE3161798D1 (ro) |
| DK (1) | DK152131C (ro) |
| EG (2) | EG16504A (ro) |
| ES (1) | ES507706A0 (ro) |
| FI (1) | FI72726C (ro) |
| FR (1) | FR2495157A1 (ro) |
| GR (1) | GR78022B (ro) |
| HK (1) | HK61585A (ro) |
| HU (1) | HU185070B (ro) |
| IE (1) | IE51710B1 (ro) |
| IL (1) | IL64148A (ro) |
| IN (1) | IN155555B (ro) |
| MA (1) | MA19332A1 (ro) |
| MY (1) | MY8600007A (ro) |
| NO (1) | NO155666C (ro) |
| NZ (1) | NZ199023A (ro) |
| OA (1) | OA06952A (ro) |
| PH (1) | PH19848A (ro) |
| PL (1) | PL127918B1 (ro) |
| PT (1) | PT73989B (ro) |
| RO (1) | RO83468B (ro) |
| SU (1) | SU1176843A3 (ro) |
| TR (1) | TR21229A (ro) |
| YU (1) | YU42595B (ro) |
| ZA (1) | ZA817876B (ro) |
| ZW (1) | ZW27281A1 (ro) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2495156A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique |
| FR2528848A1 (fr) * | 1982-06-16 | 1983-12-23 | Sanofi Sa | Nouveau derive de thieno-pyridone, son procede de preparation et son application therapeutique |
| FR2576901B1 (fr) * | 1985-01-31 | 1987-03-20 | Sanofi Sa | Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique |
| CA1337695C (en) * | 1988-09-23 | 1995-12-05 | Jacques Gosteli | Process for the production of 4,5,6,7-tetrahydrothieno-¬3,2-c|-pyridines |
| FR2652579B1 (fr) * | 1989-10-02 | 1992-01-24 | Sanofi Sa | Derives d'hydroxy-2 thiophene et furanne condenses avec un cycle azote, sur procede de preparation et leur application en therapeutique. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2215948B1 (ro) * | 1973-02-01 | 1976-05-14 | Centre Etd Ind Pharma | |
| FR2338703A1 (fr) * | 1976-01-22 | 1977-08-19 | Parcor | Derives de thieno (3,2-c) pyridine, leur procede de preparation et leurs applications |
-
1980
- 1980-11-28 FR FR8025275A patent/FR2495157A1/fr active Granted
-
1981
- 1981-10-14 DE DE8181401595T patent/DE3161798D1/de not_active Expired
- 1981-10-14 CY CY1280A patent/CY1280A/xx unknown
- 1981-10-14 EP EP81401595A patent/EP0053949B1/fr not_active Expired
- 1981-10-14 AT AT81401595T patent/ATE5725T1/de not_active IP Right Cessation
- 1981-10-28 IL IL64148A patent/IL64148A/xx unknown
- 1981-10-30 DK DK480681A patent/DK152131C/da not_active IP Right Cessation
- 1981-11-02 FI FI813436A patent/FI72726C/fi not_active IP Right Cessation
- 1981-11-04 EG EG638/81A patent/EG16504A/xx active
- 1981-11-04 EG EG636/81A patent/EG15453A/xx active
- 1981-11-06 IN IN1237/CAL/81A patent/IN155555B/en unknown
- 1981-11-11 PH PH26484A patent/PH19848A/en unknown
- 1981-11-11 ZW ZW272/81A patent/ZW27281A1/xx unknown
- 1981-11-12 AU AU77431/81A patent/AU543463B2/en not_active Ceased
- 1981-11-13 MA MA19536A patent/MA19332A1/fr unknown
- 1981-11-13 ZA ZA817876A patent/ZA817876B/xx unknown
- 1981-11-13 PT PT73989A patent/PT73989B/pt unknown
- 1981-11-14 OA OA57548A patent/OA06952A/xx unknown
- 1981-11-16 BG BG054163A patent/BG36347A3/xx unknown
- 1981-11-16 AR AR287458A patent/AR228166A1/es active
- 1981-11-16 ES ES507706A patent/ES507706A0/es active Granted
- 1981-11-17 IE IE2685/81A patent/IE51710B1/en unknown
- 1981-11-17 GR GR66544A patent/GR78022B/el unknown
- 1981-11-20 NZ NZ199023A patent/NZ199023A/en unknown
- 1981-11-24 TR TR21229A patent/TR21229A/xx unknown
- 1981-11-25 CS CS818684A patent/CS224635B2/cs unknown
- 1981-11-26 DD DD81235155A patent/DD201798A5/de unknown
- 1981-11-26 PL PL1981233981A patent/PL127918B1/pl unknown
- 1981-11-27 CA CA000391063A patent/CA1182116A/en not_active Expired
- 1981-11-27 NO NO814056A patent/NO155666C/no unknown
- 1981-11-27 KR KR1019810004594A patent/KR870000823B1/ko active IP Right Grant
- 1981-11-27 HU HU813561A patent/HU185070B/hu not_active IP Right Cessation
- 1981-11-27 RO RO105884A patent/RO83468B/ro unknown
- 1981-11-27 SU SU813358458A patent/SU1176843A3/ru active
- 1981-11-27 YU YU2789/81A patent/YU42595B/xx unknown
- 1981-11-30 US US06/325,795 patent/US4424356A/en not_active Expired - Fee Related
-
1985
- 1985-08-15 HK HK615/85A patent/HK61585A/xx unknown
-
1986
- 1986-12-30 MY MY7/86A patent/MY8600007A/xx unknown
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