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RO80923B - Procedeu pentru prepararea unor derivati de piranona - Google Patents

Procedeu pentru prepararea unor derivati de piranona

Info

Publication number
RO80923B
RO80923B RO101942A RO10194280A RO80923B RO 80923 B RO80923 B RO 80923B RO 101942 A RO101942 A RO 101942A RO 10194280 A RO10194280 A RO 10194280A RO 80923 B RO80923 B RO 80923B
Authority
RO
Romania
Prior art keywords
general formula
radical
preparation
alkyl
halogen atom
Prior art date
Application number
RO101942A
Other languages
English (en)
Other versions
RO80923A (ro
Inventor
Alvin Willard
Frederick Novello Novello
William Hoffman
Edward Cragoe Jr.
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of RO80923A publication Critical patent/RO80923A/ro
Publication of RO80923B publication Critical patent/RO80923B/ro

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B3/00—Measuring instruments characterised by the use of mechanical techniques
    • G01B3/22—Feeler-pin gauges, e.g. dial gauges
    • G01B3/28—Depth gauges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B5/00—Measuring arrangements characterised by the use of mechanical techniques
    • G01B5/18—Measuring arrangements characterised by the use of mechanical techniques for measuring depth
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B3/00—Engines characterised by air compression and subsequent fuel addition
    • F02B3/06—Engines characterised by air compression and subsequent fuel addition with compression ignition

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • A Measuring Device Byusing Mechanical Method (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Inventia se refera la un procedeu pentru prepararea unor derivati de piranona, hipocolesterolemici sau hipolipemici care prezinta formula generala I: (vezi form. in desc.) în care E reprezinta -CH2-CH2-sau -CH=CH-, R1 reprezinta un radical alchil inferior sau un atom de halogen în pozitia 2, R2 este un radical alchil inferior sau un atom de halogen în pozitia 4, R3 reprezinta un radical halofenilalcoxi cu 1...3 atomi de carbon halofenoxi sau fenil substituit cu halohen si/sau alchil inferior în pozitia 6, plecînd de la o aldehida cu formula generala II: (vezi form. in desc.) care se supune reactiei cu dianionul acidului acetoacetic din esterul alchilic al acidului acetoacetic obtinîndu-se un compus cu formula generala III, urmata de tratarea cu NaBH4 într-un alcanol inferior la sau sub temoperatura camerei, dupa care compusul obtinut poate fi saponificat, lactonizat si apot fi reduse legaturile duble în grupa E si separati anatiomerii prin metode cunoscute.
RO101942A 1979-08-17 1980-08-08 Procedeu pentru prepararea unor derivati de piranona RO80923B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/067,547 US4283857A (en) 1979-08-17 1979-08-17 Spindle-height gage and method of calibration

Publications (2)

Publication Number Publication Date
RO80923A RO80923A (ro) 1983-04-29
RO80923B true RO80923B (ro) 1983-04-30

Family

ID=22076733

Family Applications (1)

Application Number Title Priority Date Filing Date
RO101942A RO80923B (ro) 1979-08-17 1980-08-08 Procedeu pentru prepararea unor derivati de piranona

Country Status (2)

Country Link
US (1) US4283857A (ro)
RO (1) RO80923B (ro)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879819A (en) * 1988-10-05 1989-11-14 Crawford Fitting Company Gauge for coupling component
US5492003A (en) * 1994-11-23 1996-02-20 Northrop Grumman Corporation Electronic gap measuring tool
US5639953A (en) * 1996-02-26 1997-06-17 Hanson Research Corporation Alignment verification device for a rotating shaft
JP3081174B2 (ja) * 1997-07-08 2000-08-28 株式会社東京精密 真円度測定機及びその検出器感度校正方法
JP6537950B2 (ja) * 2015-09-30 2019-07-03 株式会社ミツトヨ ゲージ検査機
KR101906734B1 (ko) 2017-08-28 2018-10-10 태양금속공업주식회사 아웃풋 로드 컵 검사용 지그

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3016619A (en) * 1957-12-19 1962-01-16 Kurt H Mueller Depth and groove locating gage
US2965970A (en) * 1958-05-22 1960-12-27 Leopold A Rocheleau Combination test set, gauge, comparator, and dial indicator
US3046665A (en) * 1959-08-24 1962-07-31 John C Nilsson Gauge assembly

Also Published As

Publication number Publication date
RO80923A (ro) 1983-04-29
US4283857A (en) 1981-08-18

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