RO77543A - Procedeu de preparare a unor 8-tiometil-ergoline - Google Patents

Procedeu de preparare a unor 8-tiometil-ergoline

Info

Publication number: RO77543A
Authority: RO; Romania
Prior art keywords: ergolines; thiomethyl; preparation; thiomethyl ergolines
Prior art date: 1974-06-06

Application number

RO7582445A

Other languages

English (en)

French (fr)

Inventor

Edmund C Kornfeld

Nicholas J Bach

Original Assignee

Eli Lilly And Co,Us

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-05

Publication date

1982-02-26

1975-06-05 Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us

1982-02-26 Publication of RO77543A publication Critical patent/RO77543A/ro

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

RO7582445A 1974-06-06 1975-06-05 Procedeu de preparare a unor 8-tiometil-ergoline RO77543A (ro)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines

Publications (1)

Publication Number	Publication Date
RO77543A true RO77543A (ro)	1982-02-26

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RO7582445A RO77543A (ro)	1974-06-06	1975-06-05	Procedeu de preparare a unor 8-tiometil-ergoline

Country Status (27)

Country	Link
US (1)	US3901894A (ro)
JP (1)	JPS582946B2 (ro)
AR (1)	AR210736A1 (ro)
AT (1)	AT344333B (ro)
AU (1)	AU507574B2 (ro)
BE (1)	BE829887A (ro)
BG (1)	BG24812A3 (ro)
CA (1)	CA1071623A (ro)
CH (1)	CH617196A5 (ro)
CS (1)	CS199591B2 (ro)
DD (1)	DD120438A5 (ro)
DE (1)	DE2524575A1 (ro)
DK (1)	DK144160C (ro)
ES (1)	ES438313A1 (ro)
FR (1)	FR2273542A1 (ro)
GB (1)	GB1505296A (ro)
HU (1)	HU173590B (ro)
IE (1)	IE41474B1 (ro)
IL (1)	IL47424A (ro)
NL (1)	NL180911C (ro)
PH (1)	PH10992A (ro)
PL (1)	PL95738B1 (ro)
RO (1)	RO77543A (ro)
SE (1)	SE420095B (ro)
SU (1)	SU613724A3 (ro)
YU (1)	YU145575A (ro)
ZA (1)	ZA753638B (ro)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) *	1977-07-05	1988-03-31	Simes	Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (de) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Pharmazeutische zubereitungen mit zytostatischer wirkung
FR2526797A1 (fr) *	1982-05-12	1983-11-18	Roussel Uclaf	Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CH649998A5 (de) *	1982-08-09	1985-06-28	Sandoz Ag	Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) *	1985-11-13	1988-09-02	Roussel Uclaf	Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
CA2449634C (en) *	2001-06-08	2011-08-02	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R	Somatostatin-dopamine chimeric analogs
ATE414704T1 (de) *	2002-03-15	2008-12-15	Antibioticos Spa	Verfahren zur synthese von pergolid
TWI523863B (zh)	2012-11-01	2016-03-01	艾普森藥品公司	體抑素－多巴胺嵌合體類似物
JP2016503402A (ja)	2012-11-01	2016-02-04	イプセンファルマソシエテパールアクシオンサンプリフィエＩｐｓｅｎＰｈａｒｍａＳ．Ａ．Ｓ．	ソマトスタチン類似体及びそのダイマー
MX2017003716A (es)	2014-09-25	2017-06-30	Boehringer Ingelheim Vetmedica Gmbh	Tratamiento de combinacion y/o prevencion de transtorno metabolicos en animales equinos.
US20190374534A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH507248A (de) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
DE1935556A1 (de) *	1969-07-12	1971-01-21	Hoechst Ag	Verfahren zur Herstellung von Lysergol
JPS5012398A (ro) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/ja not_active Expired
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/xx not_active IP Right Cessation
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 CS CS753882A patent/CS199591B2/cs unknown
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 HU HU75EI623A patent/HU173590B/hu unknown
- 1975-06-03 SE SE7506327A patent/SE420095B/xx not_active IP Right Cessation
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/de not_active Ceased
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 PL PL1975180897A patent/PL95738B1/pl unknown
- 1975-06-04 DK DK249975A patent/DK144160C/da not_active IP Right Cessation
- 1975-06-04 BG BG030188A patent/BG24812A3/xx unknown
- 1975-06-04 IL IL47424A patent/IL47424A/xx unknown
- 1975-06-05 SU SU752140862A patent/SU613724A3/ru active
- 1975-06-05 AT AT427975A patent/AT344333B/de not_active IP Right Cessation
- 1975-06-05 FR FR7517652A patent/FR2273542A1/fr active Granted
- 1975-06-05 ZA ZA3638A patent/ZA753638B/xx unknown
- 1975-06-05 BE BE1006709A patent/BE829887A/xx not_active IP Right Cessation
- 1975-06-05 YU YU01455/75A patent/YU145575A/xx unknown
- 1975-06-05 RO RO7582445A patent/RO77543A/ro unknown
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
- 1975-06-06 ES ES438313A patent/ES438313A1/es not_active Expired
- 1975-06-06 AR AR259118A patent/AR210736A1/es active
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Also Published As

Publication number	Publication date
CS199591B2 (en)	1980-07-31
CH617196A5 (ro)	1980-05-14
DK144160B (da)	1981-12-28
ES438313A1 (es)	1977-05-16
DK249975A (da)	1975-12-07
DD120438A5 (ro)	1976-06-12
NL180911C (nl)	1987-05-18
NL7506584A (nl)	1975-12-09
IL47424A (en)	1979-11-30
AU8182775A (en)	1976-12-09
DK144160C (da)	1982-06-07
PL95738B1 (pl)	1977-11-30
CA1071623A (en)	1980-02-12
HU173590B (hu)	1979-06-28
SE420095B (sv)	1981-09-14
SE7506327L (sv)	1975-12-08
AR210736A1 (es)	1977-09-15
SU613724A3 (ru)	1978-06-30
BG24812A3 (en)	1978-05-12
JPS582946B2 (ja)	1983-01-19
YU145575A (en)	1982-02-28
ZA753638B (en)	1977-01-26
BE829887A (fr)	1975-12-05
IE41474B1 (en)	1980-01-16
IL47424A0 (en)	1975-08-31
DE2524575A1 (de)	1975-12-18
IE41474L (en)	1975-12-06
GB1505296A (en)	1978-03-30
PH10992A (en)	1977-10-20
AU507574B2 (en)	1980-02-21
US3901894A (en)	1975-08-26
JPS50160300A (ro)	1975-12-25
AT344333B (de)	1978-07-10
FR2273542B1 (ro)	1978-10-06
FR2273542A1 (fr)	1976-01-02
ATA427975A (de)	1977-11-15
NL180911B (nl)	1986-12-16

Publication	Publication Date	Title
RO69763A (ro)	1982-02-26	Procedeu pentru prepararea unor compusi de 3-ariloxi-3-fenilpropilamina
RO77543A (ro)	1982-02-26	Procedeu de preparare a unor 8-tiometil-ergoline
BE833823A (fr)	1976-03-25	Procede de preparation de polyurethannes
BE831843A (fr)	1976-01-29	Procede de preparation de polyurees
RO70525A (ro)	1981-09-24	Procedeu de preparare a unor bifeniloxi-derivati
FR2283114A1 (fr)	1976-03-26	Procede de preparation de butanediols
RO70581A (ro)	1982-05-10	Procedeu de preparare a unor amidoxime
BE844736A (fr)	1977-01-31	Procede de preparation de resorcines
BE828672A (fr)	1975-11-03	Procede de preparation du butyne-diol
FR2277059A1 (fr)	1976-01-30	Procede de preparation de cyclo-alcenes
RO72528A (ro)	1981-11-04	Procedeu de preparare a clorhidratului de 6-dezoxi-5hidroxitetraciclinei
BE832428A (fr)	1976-02-16	Procede de preparation de 2-methyl-tetra-hydropyrimidines 1- substituees
BE829779A (fr)	1975-12-02	Procede de preparation de pyrazolo-benzazepines
RO72708A (ro)	1982-09-09	Procedeu de preparare a perclormetilnercaptanului
FR2277060A1 (fr)	1976-01-30	Procede de preparation de monoalcenylbenzenes
BE813169A (fr)	1974-10-02	Procede de preparation des 3-fluorocephalosporines
BE842735A (fr)	1976-12-09	Procede de preparation de para-alkylphenols
BE837051A (fr)	1976-06-24	Procede de preparation de pinacoline
FR2311010A1 (fr)	1976-12-10	Procede de preparation de 2-aryl-2h-benzotriazoles
FR2279778A1 (fr)	1976-02-20	Procede de preparation de polyurees
RO66137A (ro)	1980-02-15	Procedeu pentru prepararea clorhidratului de carnitina
FR2281937A1 (fr)	1976-03-12	Procede de preparation de palmitates de steryl-b-d-glucoside
RO72510A (ro)	1982-09-09	Procedeu de preparare a unor fenilpirazine
FR2353516A2 (fr)	1977-12-30	Procede de preparation de fluoronitrobenzenes
FR2275467A1 (fr)	1976-01-16	Procede de preparation de 1-aminomethyltriazolobenzodiazepines