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PT96410A - Processo de preparacao de tri-iodo-isoftalamidas - Google Patents

Processo de preparacao de tri-iodo-isoftalamidas

Info

Publication number
PT96410A
PT96410A PT96410A PT9641091A PT96410A PT 96410 A PT96410 A PT 96410A PT 96410 A PT96410 A PT 96410A PT 9641091 A PT9641091 A PT 9641091A PT 96410 A PT96410 A PT 96410A
Authority
PT
Portugal
Prior art keywords
isoftalamides
iodo
tri
preparation process
compounds
Prior art date
Application number
PT96410A
Other languages
English (en)
Other versions
PT96410B (pt
Inventor
Michel Schaefer
Maryse Dugast-Zrihen
Michel Guillemot
Didier Doucet
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of PT96410A publication Critical patent/PT96410A/pt
Publication of PT96410B publication Critical patent/PT96410B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT96410A 1990-01-05 1991-01-03 Processo de preparacao de tri-iodo-isoftalamidas PT96410B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9000106A FR2656865B1 (fr) 1990-01-05 1990-01-05 Compose non ionique iode, son procede de preparation et produit de contraste le contenant.

Publications (2)

Publication Number Publication Date
PT96410A true PT96410A (pt) 1991-10-15
PT96410B PT96410B (pt) 1998-06-30

Family

ID=9392557

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96410A PT96410B (pt) 1990-01-05 1991-01-03 Processo de preparacao de tri-iodo-isoftalamidas

Country Status (25)

Country Link
EP (1) EP0437144B1 (pt)
JP (1) JP2529032B2 (pt)
KR (1) KR100194506B1 (pt)
AT (1) ATE114639T1 (pt)
CA (1) CA2050334C (pt)
CZ (1) CZ283986B6 (pt)
DE (1) DE69014581T2 (pt)
DK (1) DK0437144T3 (pt)
ES (1) ES2067710T3 (pt)
FI (1) FI102746B1 (pt)
FR (1) FR2656865B1 (pt)
GR (1) GR3015183T3 (pt)
HK (1) HK1006019A1 (pt)
HU (1) HUT59079A (pt)
IE (1) IE65329B1 (pt)
IL (1) IL96812A (pt)
NO (1) NO180297C (pt)
NZ (1) NZ236675A (pt)
PL (1) PL165683B1 (pt)
PT (1) PT96410B (pt)
RO (1) RO108559B1 (pt)
SK (1) SK279646B6 (pt)
TR (1) TR24944A (pt)
WO (1) WO1991009836A1 (pt)
ZA (1) ZA9173B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687669B1 (fr) * 1992-02-24 1997-12-19 Guerbet Sa Composes utilisables dans des produits de contraste pour la radiographie.
IT1256163B (it) * 1992-10-27 1995-11-29 Zambon Spa Processo per la preparazione di un intermedio della sintesi organica
IT1283319B1 (it) * 1996-03-29 1998-04-16 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
CN108947959B (zh) * 2017-05-27 2022-09-20 正大天晴药业集团股份有限公司 一种非离子型碘造影剂中间体的制备方法
CN110903275A (zh) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 制备碘比醇的方法、其中间体及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
DE3429949A1 (de) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel
IL90326A (en) * 1988-06-02 1993-05-13 Guerbet Sa Non-ionic triiodobenzene compounds and contrast media containing them

Also Published As

Publication number Publication date
PT96410B (pt) 1998-06-30
EP0437144A1 (fr) 1991-07-17
KR100194506B1 (ko) 1999-06-15
FR2656865B1 (fr) 1993-03-26
NO913403L (no) 1991-08-30
IE65329B1 (en) 1995-10-18
PL288603A1 (en) 1992-04-06
RO108559B1 (ro) 1994-06-30
CZ283986B6 (cs) 1998-07-15
DK0437144T3 (da) 1995-01-23
WO1991009836A1 (fr) 1991-07-11
KR920701132A (ko) 1992-08-11
JP2529032B2 (ja) 1996-08-28
FR2656865A1 (fr) 1991-07-12
IE910035A1 (en) 1991-07-17
FI102746B (fi) 1999-02-15
NO913403D0 (no) 1991-08-30
FI102746B1 (fi) 1999-02-15
TR24944A (tr) 1992-07-01
GR3015183T3 (en) 1995-05-31
CA2050334C (en) 1999-09-07
PL165683B1 (pl) 1995-01-31
HK1006019A1 (en) 1999-02-05
ZA9173B (en) 1992-08-26
DE69014581T2 (de) 1995-06-08
SK279646B6 (sk) 1999-01-11
ES2067710T3 (es) 1995-04-01
AU7057491A (en) 1991-07-24
NO180297C (no) 1997-03-26
FI914114A (fi) 1992-06-29
IL96812A (en) 1995-05-26
CA2050334A1 (en) 1991-07-06
EP0437144B1 (fr) 1994-11-30
NZ236675A (en) 1992-08-26
ATE114639T1 (de) 1994-12-15
JPH05132455A (ja) 1993-05-28
HU912860D0 (en) 1992-02-28
HUT59079A (en) 1992-04-28
DE69014581D1 (de) 1995-01-12
IL96812A0 (en) 1991-09-16
CS648290A3 (en) 1992-02-19
AU641212B2 (en) 1993-09-16
NO180297B (no) 1996-12-16
FI914114A0 (fi) 1991-09-02

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910531

FG3A Patent granted, date of granting

Effective date: 19980330

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20130401