PT895988E - Derivados do acido arilsulfonilamino-hidroxamico - Google Patents
Derivados do acido arilsulfonilamino-hidroxamicoInfo
- Publication number
- PT895988E PT895988E PT98305959T PT98305959T PT895988E PT 895988 E PT895988 E PT 895988E PT 98305959 T PT98305959 T PT 98305959T PT 98305959 T PT98305959 T PT 98305959T PT 895988 E PT895988 E PT 895988E
- Authority
- PT
- Portugal
- Prior art keywords
- arylsulphonylamino
- aryl
- acid derivatives
- hydroxamic acid
- angiogenisis
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 125000000041 C6-C10 aryl group Chemical group 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000006386 Bone Resorption Diseases 0.000 abstract 1
- 206010014989 Epidermolysis bullosa Diseases 0.000 abstract 1
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010039705 Scleritis Diseases 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 230000024279 bone resorption Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 230000036303 septic shock Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5520897P | 1997-08-08 | 1997-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT895988E true PT895988E (pt) | 2002-09-30 |
Family
ID=21996365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98305959T PT895988E (pt) | 1997-08-08 | 1998-07-27 | Derivados do acido arilsulfonilamino-hidroxamico |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0895988B1 (pt) |
| JP (1) | JPH11116549A (pt) |
| AT (1) | ATE217863T1 (pt) |
| BR (1) | BR9803128A (pt) |
| CA (1) | CA2244501C (pt) |
| DE (1) | DE69805473T2 (pt) |
| DK (1) | DK0895988T3 (pt) |
| ES (1) | ES2176913T3 (pt) |
| PT (1) | PT895988E (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PA8469601A1 (es) | 1998-04-10 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para alquilar sulfonamidas impedidas estericamente |
| GT199900044A (es) * | 1998-04-10 | 2000-09-14 | Procedimientos para preparar haluros de fenoxifenilsulfonilo. | |
| PA8469301A1 (es) | 1998-04-10 | 2000-09-29 | Pfizer Prod Inc | Procedimientos para la preparacion de acidos hidroxamicos. |
| AU3196300A (en) * | 1999-03-26 | 2000-10-16 | Shionogi & Co., Ltd. | Carbocyclic sulfonamide derivatives |
| DK1041072T3 (da) * | 1999-03-31 | 2003-11-10 | Pfizer Prod Inc | Dioxocyclopentylhydroxamsyrer |
| IL138686A0 (en) | 1999-10-01 | 2001-10-31 | Pfizer Prod Inc | α- SULFONYLAMINO HYDROXAMIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES FOR THE TREATMENT OF PERIPHERAL OR CENTRAL NERVOUS SYSTEM DISORDERS |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| US7141607B1 (en) | 2000-03-10 | 2006-11-28 | Insite Vision Incorporated | Methods and compositions for treating and inhibiting retinal neovascularization |
| AU2001245891A1 (en) | 2000-03-21 | 2001-10-03 | The Procter & Gamble Company | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors |
| IL151250A0 (en) | 2000-03-21 | 2003-04-10 | Procter & Gamble | Difluorobutyric acid metalloprotease inhibitors |
| CA2372352A1 (en) * | 2000-04-07 | 2001-10-18 | Hyun-Gyu Park | Sulfonamide derivative as a matrix metalloproteinase inhibitor |
| EP1365745A2 (en) | 2001-02-15 | 2003-12-03 | King Pharmaceuticals, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| US20040235896A1 (en) * | 2001-03-14 | 2004-11-25 | Fujimoto Roger Aki | Certain azacycloalkyl substituted acetic acid derivatives |
| KR101038585B1 (ko) | 2001-06-26 | 2011-06-03 | 암젠 인코포레이티드 | Ｏｐｇｌ 에 결합하는 항체, 이의 조성물 및 이의 제조방법 |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| WO2003042176A1 (fr) * | 2001-11-13 | 2003-05-22 | Shiseido Co., Ltd. | Compose azabicyclo, inhibiteur de metalloprotease matricielle et preparation cutanee |
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
| EP1466899A4 (en) | 2001-12-27 | 2010-01-06 | Dainippon Sumitomo Pharma Co | "HYDROXAMIC ACID DERIVATIVE AND MMP INHIBITOR CONTAINING THEM AS AN ACTIVE SUBSTANCE" |
| AU2003299971A1 (en) | 2002-12-30 | 2004-07-29 | Amgen Inc. | Combination therapy with co-stimulatory factors |
| GB0326546D0 (en) * | 2003-11-14 | 2003-12-17 | Amersham Plc | Inhibitor imaging agents |
| ZA200605248B (en) | 2003-12-15 | 2007-10-31 | Japan Tobacco Inc | Cyclopropane compounds and pharmaceutical use thereof |
| CA2549598A1 (en) * | 2003-12-15 | 2005-06-30 | Japan Tobacco Inc. | N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10507158A (ja) * | 1994-06-22 | 1998-07-14 | ブリティッシュ バイオテック ファーマシューティカルズ リミテッド | 金属タンパク質分解酵素阻害剤 |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| SK21499A3 (en) * | 1996-08-23 | 2000-05-16 | Pfizer | Arylsulfonylamino hydroxamic acid derivatives |
-
1998
- 1998-07-27 PT PT98305959T patent/PT895988E/pt unknown
- 1998-07-27 AT AT98305959T patent/ATE217863T1/de not_active IP Right Cessation
- 1998-07-27 ES ES98305959T patent/ES2176913T3/es not_active Expired - Lifetime
- 1998-07-27 DE DE69805473T patent/DE69805473T2/de not_active Expired - Fee Related
- 1998-07-27 EP EP98305959A patent/EP0895988B1/en not_active Expired - Lifetime
- 1998-07-27 DK DK98305959T patent/DK0895988T3/da active
- 1998-08-03 JP JP10218971A patent/JPH11116549A/ja active Pending
- 1998-08-06 CA CA002244501A patent/CA2244501C/en not_active Expired - Fee Related
- 1998-08-10 BR BR9803128-7A patent/BR9803128A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69805473D1 (de) | 2002-06-27 |
| JPH11116549A (ja) | 1999-04-27 |
| ATE217863T1 (de) | 2002-06-15 |
| ES2176913T3 (es) | 2002-12-01 |
| BR9803128A (pt) | 2000-05-02 |
| CA2244501C (en) | 2003-03-18 |
| DK0895988T3 (da) | 2002-09-09 |
| EP0895988B1 (en) | 2002-05-22 |
| DE69805473T2 (de) | 2003-01-16 |
| EP0895988A1 (en) | 1999-02-10 |
| CA2244501A1 (en) | 1999-02-08 |
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