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PT84187B - Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem

Info

Publication number
PT84187B
PT84187B PT84187A PT8418787A PT84187B PT 84187 B PT84187 B PT 84187B PT 84187 A PT84187 A PT 84187A PT 8418787 A PT8418787 A PT 8418787A PT 84187 B PT84187 B PT 84187B
Authority
PT
Portugal
Prior art keywords
isokinoline
preparation
pharmaceutical compositions
compositions containing
new derivatives
Prior art date
Application number
PT84187A
Other languages
English (en)
Other versions
PT84187A (pt
Original Assignee
Zambeletti Spa L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambeletti Spa L filed Critical Zambeletti Spa L
Publication of PT84187A publication Critical patent/PT84187A/pt
Publication of PT84187B publication Critical patent/PT84187B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT84187A 1986-01-24 1987-01-22 Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem PT84187B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868601796A GB8601796D0 (en) 1986-01-24 1986-01-24 Compounds

Publications (2)

Publication Number Publication Date
PT84187A PT84187A (pt) 1987-02-01
PT84187B true PT84187B (pt) 1989-09-14

Family

ID=10591914

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84187A PT84187B (pt) 1986-01-24 1987-01-22 Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem

Country Status (10)

Country Link
US (1) US4806547A (pt)
EP (1) EP0232989B1 (pt)
JP (1) JPH0780855B2 (pt)
AU (1) AU595281B2 (pt)
DE (1) DE3772218D1 (pt)
DK (1) DK35687A (pt)
GB (1) GB8601796D0 (pt)
NZ (1) NZ219030A (pt)
PT (1) PT84187B (pt)
ZA (1) ZA87467B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3670080D1 (de) * 1985-12-23 1990-05-10 Zambeletti Spa L Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika.
DE68910999T2 (de) * 1988-02-19 1994-03-24 Smithkline Beecham Farma 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten.
PT89780A (pt) * 1988-02-23 1989-10-04 Glaxo Group Ltd Processo para a preparacao de derivados da tetrahidroisoquinolina
EP0330467A1 (en) * 1988-02-23 1989-08-30 Glaxo Group Limited Heterocyclic compounds
AU616488B2 (en) * 1988-03-16 1991-10-31 Dr. Lo Zambeletti S.P.A. Heterocyclic derivatives
GB8824291D0 (en) * 1988-10-17 1988-11-23 Zambeletti Spa L Novel use
GB8824400D0 (en) * 1988-10-18 1988-11-23 Glaxo Group Ltd Chemical compounds
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8830219D0 (en) * 1988-12-23 1989-02-22 Zambeletti Spa L Novel compounds
DE3935371A1 (de) * 1988-12-23 1990-07-05 Merck Patent Gmbh Stickstoffhaltige ringverbindungen
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
GB8926560D0 (en) * 1989-11-24 1990-01-17 Zambeletti Spa L Pharmaceuticals
JPH05506650A (ja) * 1990-04-28 1993-09-30 スミスクライン　ビーチャム　ファルマシューティッチ　エッセ　ピ　ア アザ環式誘導体
DE4215213A1 (de) * 1992-05-09 1993-11-11 Merck Patent Gmbh Arylacetamide
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
TW436484B (en) * 1996-04-24 2001-05-28 Dev Center Biotechnology 1,2,3,4-tetrahydroisoquinoline derivatives having a nitrogen-containing heterocyclic methyl substituent, the preparation process and pharmaceutical composition thereof
BRPI0809651A2 (pt) * 2007-03-30 2014-10-07 Tioga Pharmaceuticals Inc Agonistas de kappa-opiato para o tratamento de síndrome do cólon irritável de diarreia predominante ou alternada

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
HU189764B (en) * 1983-10-25 1986-07-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds

Also Published As

Publication number Publication date
EP0232989A3 (en) 1988-06-22
ZA87467B (en) 1987-11-25
EP0232989B1 (en) 1991-08-21
US4806547A (en) 1989-02-21
DK35687D0 (da) 1987-01-22
NZ219030A (en) 1990-06-26
AU595281B2 (en) 1990-03-29
GB8601796D0 (en) 1986-02-26
JPH0780855B2 (ja) 1995-08-30
EP0232989A2 (en) 1987-08-19
DK35687A (da) 1987-07-25
JPS62240665A (ja) 1987-10-21
PT84187A (pt) 1987-02-01
AU6791587A (en) 1987-07-30
DE3772218D1 (de) 1991-09-26

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Legal Events

Date Code Title Description
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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19920831