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PT1691825E - Formulações líquidas de interferão estabilizadas - Google Patents

Formulações líquidas de interferão estabilizadas Download PDF

Info

Publication number
PT1691825E
PT1691825E PT04820468T PT04820468T PT1691825E PT 1691825 E PT1691825 E PT 1691825E PT 04820468 T PT04820468 T PT 04820468T PT 04820468 T PT04820468 T PT 04820468T PT 1691825 E PT1691825 E PT 1691825E
Authority
PT
Portugal
Prior art keywords
interferon
formulations
cyclodextrin
room temperature
stable
Prior art date
Application number
PT04820468T
Other languages
English (en)
Inventor
Maria Dorly Del Curto
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of PT1691825E publication Critical patent/PT1691825E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PT04820468T 2003-12-11 2004-12-10 Formulações líquidas de interferão estabilizadas PT1691825E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03104646 2003-12-11
EP04103349 2004-07-13

Publications (1)

Publication Number Publication Date
PT1691825E true PT1691825E (pt) 2011-10-12

Family

ID=34702349

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04820468T PT1691825E (pt) 2003-12-11 2004-12-10 Formulações líquidas de interferão estabilizadas

Country Status (18)

Country Link
US (1) US7846427B2 (pt)
EP (1) EP1691825B1 (pt)
JP (1) JP4658961B2 (pt)
AT (1) ATE526032T1 (pt)
AU (1) AU2004298781B2 (pt)
BR (1) BRPI0416980A (pt)
CA (1) CA2547822A1 (pt)
CY (1) CY1112193T1 (pt)
DK (1) DK1691825T3 (pt)
ES (1) ES2374530T3 (pt)
HR (1) HRP20110699T1 (pt)
IL (1) IL176021A0 (pt)
NO (1) NO20063108L (pt)
PL (1) PL1691825T3 (pt)
PT (1) PT1691825E (pt)
RS (1) RS52218B (pt)
SI (1) SI1691825T1 (pt)
WO (1) WO2005058346A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI272948B (en) * 2003-05-01 2007-02-11 Ares Trading Sa HSA-free stabilized interferon liquid formulations
CA2566364A1 (en) * 2004-05-17 2005-11-24 Ares Trading S.A. Hydrogel interferon formulations
KR20100019467A (ko) 2007-05-02 2010-02-18 암브룩스, 인코포레이티드 변형된 인터페론 베타 폴리펩티드 및 그의 용도
US7951368B2 (en) 2007-06-25 2011-05-31 Amgen Inc. Compositions of specific binding agents to hepatocyte growth factor
CA2707840A1 (en) 2007-08-20 2009-02-26 Allozyne, Inc. Amino acid substituted molecules
ATE555812T1 (de) * 2007-12-20 2012-05-15 Merck Serono Sa Peg-interferon-beta-formulierungen
US20100203014A1 (en) * 2009-02-04 2010-08-12 Aegis Therapeutics Llc Zwitterionic buffered acidic peptide and protein formulations
KR20150074167A (ko) 2012-10-26 2015-07-01 루핀 리미티드 Peg 인터페론 알파-2b의 안정한 약학 조성물
GB201604124D0 (en) * 2016-03-10 2016-04-27 Ucb Biopharma Sprl Pharmaceutical formulation
BR112020005703A2 (pt) * 2017-09-27 2020-10-20 Novartis Ag formulação parentérica compreendendo siponimod
CN111494611A (zh) * 2020-06-08 2020-08-07 长春生物制品研究所有限责任公司 一种卡式瓶多剂量笔式注射组合包装的干扰素注射液
CN113797317B (zh) * 2021-10-26 2024-01-09 科兴生物制药股份有限公司 一种组合物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997856A (en) 1988-10-05 1999-12-07 Chiron Corporation Method and compositions for solubilization and stabilization of polypeptides, especially proteins
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5814485A (en) * 1995-06-06 1998-09-29 Chiron Corporation Production of interferon-β (IFN-β) in E. coli
ZA9610374B (en) * 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
JP2001526033A (ja) * 1997-12-08 2001-12-18 ジェネンテク・インコーポレイテッド ヒトインターフェロン−イプシロンというi型インターフェロン
US6887462B2 (en) * 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
RU2004102500A (ru) * 2001-06-29 2005-04-10 Максиген Апс (Dk) Композиции интерферонов
TWI272948B (en) * 2003-05-01 2007-02-11 Ares Trading Sa HSA-free stabilized interferon liquid formulations
CA2566364A1 (en) * 2004-05-17 2005-11-24 Ares Trading S.A. Hydrogel interferon formulations
EA010979B1 (ru) * 2004-06-01 2008-12-30 Арес Трейдинг С.А. Стабилизированные жидкие препаративные формы интерферона

Also Published As

Publication number Publication date
HRP20110699T1 (hr) 2011-10-31
PL1691825T3 (pl) 2012-02-29
NO20063108L (no) 2006-07-04
US7846427B2 (en) 2010-12-07
JP4658961B2 (ja) 2011-03-23
US20070104682A1 (en) 2007-05-10
SI1691825T1 (sl) 2011-12-30
DK1691825T3 (da) 2011-12-05
IL176021A0 (en) 2006-10-05
ES2374530T3 (es) 2012-02-17
WO2005058346A1 (en) 2005-06-30
AU2004298781A1 (en) 2005-06-30
CA2547822A1 (en) 2005-06-30
RS52218B (en) 2012-10-31
BRPI0416980A (pt) 2007-02-21
EP1691825B1 (en) 2011-09-28
AU2004298781B2 (en) 2010-04-01
EP1691825A1 (en) 2006-08-23
CY1112193T1 (el) 2015-12-09
ATE526032T1 (de) 2011-10-15
JP2007513925A (ja) 2007-05-31

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