PL3501499T3 - Sposoby i kompozycje do wytwarzania aerozoli - Google Patents
Sposoby i kompozycje do wytwarzania aerozoliInfo
- Publication number
- PL3501499T3 PL3501499T3 PL19152522.9T PL19152522T PL3501499T3 PL 3501499 T3 PL3501499 T3 PL 3501499T3 PL 19152522 T PL19152522 T PL 19152522T PL 3501499 T3 PL3501499 T3 PL 3501499T3
- Authority
- PL
- Poland
- Prior art keywords
- aerosols
- compositions
- preparation
- methods
- Prior art date
Links
- 239000000443 aerosol Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30344710P | 2010-02-11 | 2010-02-11 | |
US201061426610P | 2010-12-23 | 2010-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3501499T3 true PL3501499T3 (pl) | 2023-01-09 |
Family
ID=43899571
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL19152522.9T PL3501499T3 (pl) | 2010-02-11 | 2011-02-11 | Sposoby i kompozycje do wytwarzania aerozoli |
PL11705486T PL2533761T3 (pl) | 2010-02-11 | 2011-02-11 | Sposoby i kompozycje do wytwarzania aerozoli |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL11705486T PL2533761T3 (pl) | 2010-02-11 | 2011-02-11 | Sposoby i kompozycje do wytwarzania aerozoli |
Country Status (17)
Country | Link |
---|---|
US (3) | US9713589B2 (pl) |
EP (2) | EP2533761B1 (pl) |
JP (3) | JP5951508B2 (pl) |
CN (2) | CN102753148B (pl) |
AU (1) | AU2011214299B2 (pl) |
CA (1) | CA2787718C (pl) |
CY (1) | CY1122634T1 (pl) |
DK (1) | DK2533761T3 (pl) |
ES (2) | ES2738114T3 (pl) |
HK (1) | HK1222128A1 (pl) |
HR (1) | HRP20191071T1 (pl) |
HU (1) | HUE044292T2 (pl) |
LT (1) | LT2533761T (pl) |
PL (2) | PL3501499T3 (pl) |
PT (2) | PT3501499T (pl) |
SI (1) | SI2533761T1 (pl) |
WO (1) | WO2011098552A2 (pl) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3004707C (en) | 2009-09-02 | 2022-05-31 | Synedgen Inc. | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds |
CN102753148B (zh) | 2010-02-11 | 2018-01-26 | 埃博灵克斯股份有限公司 | 用于制备气雾剂的方法和组合物 |
PT2544663T (pt) | 2010-03-12 | 2018-04-05 | Berg Llc | Formulações intravenosas de coenzima q10 (coq10) e métodos de uso da mesma |
CN107095863A (zh) * | 2011-06-17 | 2017-08-29 | 博格有限责任公司 | 可吸入药物组合物 |
EP2897587A1 (en) * | 2012-09-18 | 2015-07-29 | Adocia | Stable pharmaceutical composition, comprising an aqueous solution of an antibody-derived therapeutically active protein |
AU2014233055B2 (en) | 2013-03-15 | 2018-08-09 | Board Of Regents, The University Of Texas System | Inhibition of pulmonary fibrosis with nutlin-3a and peptides |
NL1040254C2 (en) * | 2013-05-17 | 2014-11-24 | Ablynx Nv | Stable formulations of immunoglobulin single variable domains and uses thereof. |
CA2943376C (en) * | 2014-04-03 | 2022-06-14 | Medizinische Hochschule Hannover | Nebulization of immunoglobulin |
WO2016040899A1 (en) * | 2014-09-11 | 2016-03-17 | Synedgen, Inc. | Compositions and methods of use thereof |
EP3204041A1 (en) * | 2014-10-10 | 2017-08-16 | Ablynx N.V. | Methods of treating rsv infections |
HUE044199T2 (hu) | 2014-10-10 | 2019-10-28 | Ablynx Nv | Inhalációs készülék légúti betegségek aeroszolos terápiájában való alkalmazásra |
WO2016138413A1 (en) * | 2015-02-27 | 2016-09-01 | Board Of Regents, The University Of Texas System | Polypeptide therapeutics and uses thereof |
CA3022697A1 (en) | 2016-05-02 | 2017-11-09 | Ablynx Nv | Treatment of rsv infection |
WO2018099968A1 (en) | 2016-11-29 | 2018-06-07 | Ablynx N.V. | Treatment of infection by respiratory syncytial virus (rsv) |
AU2018277343A1 (en) | 2017-06-02 | 2020-01-02 | Ablynx N.V. | Adamts binding immunoglobulins |
BR112021004404A2 (pt) | 2018-09-10 | 2021-08-03 | Lung Therapeutics, Inc. | fragmentos de peptídeos modificados da proteína cav-1 e o uso destes no tratamento de fibrose |
Family Cites Families (62)
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ES2052027T5 (es) | 1988-11-11 | 2005-04-16 | Medical Research Council | Clonacion de secuencias de dominio variable de inmunoglobulina. |
US5945098A (en) * | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
US5938117A (en) | 1991-04-24 | 1999-08-17 | Aerogen, Inc. | Methods and apparatus for dispensing liquids as an atomized spray |
EP1087013B1 (en) | 1992-08-21 | 2009-01-07 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
AU6796094A (en) | 1993-04-29 | 1994-11-21 | Raymond Hamers | Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of (camelidae) |
FR2708622B1 (fr) | 1993-08-02 | 1997-04-18 | Raymond Hamers | Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides. |
US6014970A (en) | 1998-06-11 | 2000-01-18 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US5586550A (en) | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
US6205999B1 (en) | 1995-04-05 | 2001-03-27 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US6085740A (en) | 1996-02-21 | 2000-07-11 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
EP0739981A1 (en) | 1995-04-25 | 1996-10-30 | Vrije Universiteit Brussel | Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes |
JP2000515002A (ja) | 1996-06-27 | 2000-11-14 | フラームス・インテルウニフェルジテール・インスティテュート・フォール・ビオテヒノロジー・ヴェーゼットウェー | 標的分子の活性部位またはクレフトと特異的に相互作用する認識分子 |
ATE461282T1 (de) | 1997-10-27 | 2010-04-15 | Bac Ip Bv | Multivalente antigenbindende proteine |
WO1999037681A2 (en) | 1998-01-26 | 1999-07-29 | Unilever Plc | Method for producing antibody fragments |
EP1141711A1 (en) | 1999-01-05 | 2001-10-10 | Unilever Plc | Binding of antibody fragments to solid supports |
EP1144616B2 (en) | 1999-01-19 | 2009-01-14 | Unilever Plc | Method for producing antibody fragments |
BR0009866A (pt) | 1999-04-22 | 2002-01-08 | Unilever Nv | Método de inibição de infecção viral, uso de uma proteìna de ligação de antìgeno monovalente, produto alimentìcio, composição farmacêutica ou cosmética, proteìna de ligação de antìgeno monovalente, sequência de nucleotìdeos, vetor de expressão, célula hospedeira, e, métodos de seleção e de indentificação de uma proteìna de ligação de antìgeno |
US6479280B1 (en) | 1999-09-24 | 2002-11-12 | Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw | Recombinant phages capable of entering host cells via specific interaction with an artificial receptor |
DK1233987T3 (da) | 1999-11-29 | 2009-09-28 | Bac Ip B V | Immobiliserede enkelt-domæne antigenbindende molekyler |
WO2001040310A2 (en) | 1999-11-29 | 2001-06-07 | Unilever Plc | Immobilisation of proteins using a polypeptide segment |
ES2324280T3 (es) | 2000-03-14 | 2009-08-04 | Unilever N.V. | Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos. |
US20030190598A1 (en) | 2000-05-26 | 2003-10-09 | Jasmid Tanha | Single-domain antigen-binding antibody fragments derived from llama antibodies |
ATE513854T1 (de) | 2000-12-13 | 2011-07-15 | Bac Ip B V | Proteinraster aus variablen domänen der schweren immunoglobulinkette von kamelen |
US20060073141A1 (en) | 2001-06-28 | 2006-04-06 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
US7371849B2 (en) | 2001-09-13 | 2008-05-13 | Institute For Antibodies Co., Ltd. | Methods of constructing camel antibody libraries |
JP2005289809A (ja) | 2001-10-24 | 2005-10-20 | Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) | 突然変異重鎖抗体 |
EP1456410A2 (en) | 2001-12-11 | 2004-09-15 | AlgoNomics N.V. | Method for displaying loops from immunoglobulin domains in different contexts |
EP1456237A2 (en) | 2001-12-21 | 2004-09-15 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Method for cloning of variable domain sequences |
EP1461085A2 (en) | 2002-01-03 | 2004-09-29 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Immunoconjugates useful for treatment of tumours |
US20050271660A1 (en) | 2002-09-06 | 2005-12-08 | Alexion Pharmaceuticals, Inc. | Nebulization of monoclonal antibodies for treating pulmonary diseases |
NZ540195A (en) | 2002-11-08 | 2009-01-31 | Ablynx Nv | Stabilized single domain antibodies |
AU2003283137B8 (en) | 2002-11-08 | 2010-07-29 | Ablynx N.V. | Camelidae antibodies against immunoglobulin E and use thereof for the treatment of allergic disorders |
CA2512545C (en) | 2003-01-10 | 2015-06-30 | Karen Silence | Recombinant vhh single domain antibody from camelidae against von willebrand factor (vwf) |
US7461263B2 (en) | 2003-01-23 | 2008-12-02 | Unspam, Llc. | Method and apparatus for a non-revealing do-not-contact list system |
AU2003264053A1 (en) | 2003-08-12 | 2005-03-10 | William M. Yarbrough | Treatment for acne vulgaris and method of use |
AU2003283136A1 (en) | 2003-11-07 | 2005-05-26 | Ablynx N.V. | Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor |
US7563443B2 (en) | 2004-09-17 | 2009-07-21 | Domantis Limited | Monovalent anti-CD40L antibody polypeptides and compositions thereof |
JP5113523B2 (ja) | 2004-10-13 | 2013-01-09 | アブリンクス ナームローゼ フェンノートシャップ | アミロイド−βに対するナノ抗体及びアルツハイマー病のような神経変性疾患の治療のためのナノ抗体TMを含むポリペプチド |
JP2008528010A (ja) | 2005-01-31 | 2008-07-31 | アブリンクス ナームローゼ フェンノートシャップ | 重鎖抗体の可変ドメイン配列を作出する方法 |
SI1888640T1 (sl) | 2005-05-18 | 2012-07-31 | Ablynx Nv | Izboljšana nanotelesa proti faktorju nekroze tumorja alfa |
NZ563392A (en) | 2005-05-20 | 2009-12-24 | Ablynx Nv | Improved Nanobodies(TM) for the treatment of aggregation-mediated disorders |
US20110159003A1 (en) * | 2006-01-24 | 2011-06-30 | Domantis Limited | Ligands That Bind Il-4 and/or Il-13 |
JP2009529339A (ja) | 2006-03-13 | 2009-08-20 | アブリンクス エン.ヴェー. | Il−6を標的とするアミノ酸配列およびそれを含みil−6介在シグナル伝達に関連する疾患および疾病を治療するポリペプチド |
WO2008020079A1 (en) | 2006-08-18 | 2008-02-21 | Ablynx N.V. | Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling |
JP2010502208A (ja) | 2006-09-08 | 2010-01-28 | アブリンクス エン.ヴェー. | 半減期の長い血清アルブミン結合タンパク質 |
WO2008049897A1 (en) * | 2006-10-27 | 2008-05-02 | Ablynx N.V. | Intranasal delivery of polypeptides and proteins |
WO2008071447A2 (en) | 2006-12-15 | 2008-06-19 | Ablynx N.V. | Amino acid sequences that modulate the interaction between cells of the immune system |
EP2557090A3 (en) | 2006-12-19 | 2013-05-29 | Ablynx N.V. | Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders |
EP2514767A1 (en) | 2006-12-19 | 2012-10-24 | Ablynx N.V. | Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders |
US20100166734A1 (en) | 2006-12-20 | 2010-07-01 | Edward Dolk | Oral delivery of polypeptides |
EP2097451A2 (en) | 2006-12-22 | 2009-09-09 | Ablynx N.V. | Anti-chemokine (ccl2, ccl3, ccl5, cxcl11, cxcl12) single-domain antibodies |
TW200837080A (en) * | 2007-01-09 | 2008-09-16 | Wyeth Corp | Anti-IL-13 antibody formulations and uses thereof |
JP2010518839A (ja) | 2007-02-21 | 2010-06-03 | アブリンクス エン.ヴェー. | 血管内皮増殖因子に指向性を有するアミノ酸配列、及び過度の及び/もしくは病的な血管形成又は血管新生を特徴とする症状及び疾患を治療するためにこれを含むポリペプチド |
JP5420532B2 (ja) | 2007-05-24 | 2014-02-19 | アブリンクス エン.ヴェー. | 骨疾患及び骨障害の治療のために、rank−lに指向性を有するアミノ酸配列及びこれを含むポリペプチド |
WO2008142165A1 (en) | 2007-05-24 | 2008-11-27 | Ablynx N.V. | Amino acid sequences directed against growth factor receptors and polypeptides comprising the same for the treatment of diseases and disorders associated with growth factors and their receptors |
MX2010005783A (es) | 2007-11-27 | 2010-08-10 | Ablynx Nv | Secuencias de aminoacidos dirigidas contra citoquinas heterodimericas y/o sus receptores y polipeptidos que comprenden las mismas. |
CA2707986A1 (en) * | 2007-12-13 | 2009-06-18 | Glaxo Group Limited | Compositions for pulmonary delivery |
PT2285408T (pt) | 2008-06-05 | 2019-02-01 | Ablynx Nv | Sequências de aminoácidos dirigidas contra proteínas de envelope de um vírus e polipéptidos que as compreendem para o tratamento de doenças virais |
WO2010139808A2 (en) | 2009-06-05 | 2010-12-09 | Ablynx Nv | IMPROVED AMINO ACID SEQUENCES DIRECTED AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS (hRSV) AND POLYPEPTIDES COMPRISING THE SAME FOR THE PREVENTION AND/OR TREATMENT OF RESPIRATORY TRACT INFECTIONS |
PT3438126T (pt) | 2009-09-03 | 2020-11-09 | Ablynx Nv | Formulações estáveis de polipéptidos e seus usos |
CN102753148B (zh) | 2010-02-11 | 2018-01-26 | 埃博灵克斯股份有限公司 | 用于制备气雾剂的方法和组合物 |
-
2011
- 2011-02-11 CN CN201180009097.7A patent/CN102753148B/zh active Active
- 2011-02-11 EP EP11705486.6A patent/EP2533761B1/en active Active
- 2011-02-11 ES ES11705486T patent/ES2738114T3/es active Active
- 2011-02-11 EP EP19152522.9A patent/EP3501499B1/en active Active
- 2011-02-11 PL PL19152522.9T patent/PL3501499T3/pl unknown
- 2011-02-11 WO PCT/EP2011/052024 patent/WO2011098552A2/en active Application Filing
- 2011-02-11 AU AU2011214299A patent/AU2011214299B2/en active Active
- 2011-02-11 CN CN201510824525.1A patent/CN105380904A/zh active Pending
- 2011-02-11 PL PL11705486T patent/PL2533761T3/pl unknown
- 2011-02-11 JP JP2012552404A patent/JP5951508B2/ja active Active
- 2011-02-11 DK DK11705486.6T patent/DK2533761T3/da active
- 2011-02-11 ES ES19152522T patent/ES2931330T3/es active Active
- 2011-02-11 PT PT191525229T patent/PT3501499T/pt unknown
- 2011-02-11 CA CA2787718A patent/CA2787718C/en active Active
- 2011-02-11 HU HUE11705486 patent/HUE044292T2/hu unknown
- 2011-02-11 SI SI201131740T patent/SI2533761T1/sl unknown
- 2011-02-11 US US13/577,961 patent/US9713589B2/en active Active
- 2011-02-11 PT PT11705486T patent/PT2533761T/pt unknown
- 2011-02-11 LT LTEP11705486.6T patent/LT2533761T/lt unknown
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2016
- 2016-06-08 JP JP2016114294A patent/JP6283064B2/ja active Active
- 2016-08-31 HK HK16110367.6A patent/HK1222128A1/zh unknown
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2017
- 2017-04-24 US US15/495,199 patent/US11007146B2/en active Active
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2018
- 2018-01-25 JP JP2018010149A patent/JP7019433B2/ja active Active
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2019
- 2019-06-13 HR HRP20191071TT patent/HRP20191071T1/hr unknown
- 2019-06-26 CY CY20191100668T patent/CY1122634T1/el unknown
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2021
- 2021-04-19 US US17/233,621 patent/US12083219B2/en active Active
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