PL2464664T3 - Przeciwciała przeciwko ludzkiemu syncytialnemu wirusowi oddechowemu (RSV) i sposoby zastosowania - Google Patents
Przeciwciała przeciwko ludzkiemu syncytialnemu wirusowi oddechowemu (RSV) i sposoby zastosowaniaInfo
- Publication number
- PL2464664T3 PL2464664T3 PL10747357T PL10747357T PL2464664T3 PL 2464664 T3 PL2464664 T3 PL 2464664T3 PL 10747357 T PL10747357 T PL 10747357T PL 10747357 T PL10747357 T PL 10747357T PL 2464664 T3 PL2464664 T3 PL 2464664T3
- Authority
- PL
- Poland
- Prior art keywords
- rsv
- methods
- antibodies against
- against human
- respiratory syncytial
- Prior art date
Links
- 241000711920 Human orthopneumovirus Species 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/68—Stabilisation of the vector
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27439509P | 2009-08-13 | 2009-08-13 | |
EP10747357.1A EP2464664B1 (en) | 2009-08-13 | 2010-08-13 | Antibodies against human respiratory syncytial virus (rsv) and methods of use |
PCT/US2010/045549 WO2011020079A1 (en) | 2009-08-13 | 2010-08-13 | Antibodies against human respiratory syncytial virus (rsv) and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2464664T3 true PL2464664T3 (pl) | 2016-02-29 |
Family
ID=43014487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL10747357T PL2464664T3 (pl) | 2009-08-13 | 2010-08-13 | Przeciwciała przeciwko ludzkiemu syncytialnemu wirusowi oddechowemu (RSV) i sposoby zastosowania |
Country Status (19)
Country | Link |
---|---|
US (2) | US8568719B2 (pl) |
EP (1) | EP2464664B1 (pl) |
JP (1) | JP5762408B2 (pl) |
KR (1) | KR101778317B1 (pl) |
CN (1) | CN102656189B (pl) |
BR (1) | BR112012003064B8 (pl) |
CA (1) | CA2770737C (pl) |
DK (1) | DK2464664T3 (pl) |
EA (1) | EA023179B1 (pl) |
ES (1) | ES2553440T3 (pl) |
HK (1) | HK1172350A1 (pl) |
IL (1) | IL217977A (pl) |
IN (1) | IN2012DN01328A (pl) |
MX (1) | MX2012001882A (pl) |
NZ (1) | NZ597996A (pl) |
PL (1) | PL2464664T3 (pl) |
SG (1) | SG178335A1 (pl) |
WO (1) | WO2011020079A1 (pl) |
ZA (1) | ZA201201007B (pl) |
Families Citing this family (56)
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PL2464664T3 (pl) | 2009-08-13 | 2016-02-29 | Crucell Holland Bv | Przeciwciała przeciwko ludzkiemu syncytialnemu wirusowi oddechowemu (RSV) i sposoby zastosowania |
CA3062786C (en) | 2010-07-09 | 2022-04-19 | Janssen Vaccines & Prevention B.V. | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
PT2710033T (pt) | 2011-05-17 | 2021-03-11 | Univ Rockefeller | Anticorpos neutralizantes do vírus da imunodeficiência humana e métodos de utilização destes |
JP2014518080A (ja) * | 2011-06-27 | 2014-07-28 | バルネバ | 細胞のスクリーニング方法 |
EP2729488A4 (en) * | 2011-07-06 | 2015-01-14 | Medimmune Llc | PROCESS FOR PREPARING MULTIMANT POLYPEPTIDES |
US20130165638A1 (en) * | 2011-12-27 | 2013-06-27 | Development Center For Biotechnology | Light chain-bridged bispecific antibody |
EP2825560A1 (en) * | 2012-03-13 | 2015-01-21 | Universiteit Utrecht Holding BV | Bi-specific adapters |
EA030319B1 (ru) * | 2012-03-20 | 2018-07-31 | Хумабс Биомед Са | Антитела, нейтрализующие rsv, mpv и pvm, и их применения |
MY181648A (en) | 2012-08-24 | 2020-12-30 | Univ California | Antibodies and vaccines for use in treating ror1 cancers and inhibiting metastasis |
CN103048459B (zh) * | 2012-12-05 | 2014-08-20 | 中国科学院武汉病毒研究所 | 检测呼吸道合胞病毒的免疫检测试剂 |
TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒f蛋白質的人類抗體及其使用方法 |
RU2721707C2 (ru) | 2013-03-14 | 2020-05-21 | Макродженикс, Инк. | Биспецифичные молекулы, иммунореактивные с иммунными эффекторными клетками, экспрессирующими активирующий рецептор |
DK2988780T3 (en) | 2013-04-25 | 2019-04-08 | Janssen Vaccines & Prevention Bv | STABILIZED SOLVEN RSV-F PREFUSION POLYPTIDES |
AP2015008893A0 (en) | 2013-06-17 | 2015-12-31 | Crucell Holland Bv | Stabilized soluble pre-fusion rsv f polypeptides |
EP3012633B1 (en) * | 2013-06-21 | 2018-07-18 | Alfresa Pharma Corporation | Immunochromatography device for detecting rsv |
US10047145B2 (en) | 2013-07-24 | 2018-08-14 | Humabs Biomed Sa | Antibodies that potently neutralize RSV and uses thereof |
RU2707951C1 (ru) * | 2013-11-15 | 2019-12-02 | Дженентек, Инк. | Способы инактивации вируса с использованием экологичных детергентов |
CN103911389A (zh) * | 2014-04-09 | 2014-07-09 | 南昌大学 | 一种检测人呼吸道合胞病毒抗体的g和f蛋白的制备方法 |
SG11201610459XA (en) | 2014-06-26 | 2017-01-27 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
CN105319373B (zh) * | 2014-08-18 | 2017-01-18 | 董俊 | 基于磁性分离和量子点标记的人呼吸道合胞病毒快速检测方法和试剂盒 |
US10717778B2 (en) | 2014-09-29 | 2020-07-21 | Duke University | Bispecific molecules comprising an HIV-1 envelope targeting arm |
RU2017115670A (ru) * | 2014-10-10 | 2018-11-15 | Аблинкс Н.В. | Лечение инфекции рсв |
JP2018519333A (ja) * | 2015-07-02 | 2018-07-19 | スプリング バンク ファーマシューティカルズ,インコーポレイテッド | ウイルス感染の治療のための組成物および方法 |
CA2991540A1 (en) | 2015-07-07 | 2017-01-12 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion respiratory syncytial sirus polypeptides |
KR102638978B1 (ko) | 2015-07-07 | 2024-02-22 | 얀센 백신스 앤드 프리벤션 비.브이. | Rsv에 대한 백신 |
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CN106496324B (zh) * | 2015-11-30 | 2020-01-14 | 天津昊免生物技术有限公司 | 一种抗呼吸道合胞病毒的全人源抗体 |
CN109232737A (zh) * | 2016-03-01 | 2019-01-18 | 苏州博泰神州生物技术有限公司 | 一种针对rsv粘附g蛋白表面抗原的全人源单克隆抗体 |
CN105753981B (zh) * | 2016-03-08 | 2019-10-08 | 湖北工业大学 | 抗人呼吸道合胞病毒n蛋白抗体及应用该抗体的免疫层析试剂盒 |
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WO2017174564A1 (en) | 2016-04-05 | 2017-10-12 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
US11084796B2 (en) * | 2016-05-10 | 2021-08-10 | Georgia State University Research Foundation, Inc. | Heterocyclic derivatives for the treatment of RSV |
DK3464331T3 (da) | 2016-05-30 | 2021-01-18 | Janssen Vaccines & Prevention Bv | Stabiliserede præfusions-rsv f-proteiner |
US10688181B2 (en) | 2016-06-27 | 2020-06-23 | The Regents Of The University Of California | Cancer treatment combinations |
AU2017345759B2 (en) * | 2016-10-21 | 2024-06-20 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
WO2018150029A1 (en) * | 2017-02-17 | 2018-08-23 | Institut Pasteur | Generation of monoclonal antibodies targeting respiratory syncytial virus (rsv) using regulatory b cells from newborns (nbregs) |
EP3624844A1 (en) | 2017-05-17 | 2020-03-25 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
AU2018333566A1 (en) | 2017-09-15 | 2020-02-27 | Janssen Vaccines & Prevention B.V. | Method for the safe induction of immunity against RSV |
BR112021008975A2 (pt) * | 2018-11-13 | 2021-08-17 | Janssen Vaccines & Prevention B.V. | proteínas f do rsv pré-fusão estabilizadas |
CN110016079B (zh) * | 2018-12-18 | 2019-12-24 | 珠海泰诺麦博生物技术有限公司 | 抗呼吸道合胞病毒的中和抗体及其应用 |
CL2018003869A1 (es) * | 2018-12-28 | 2021-01-15 | Univ Pontificia Catolica Chile | Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza humana (piv), secuencias nucleotídicas; método y kit de diagnóstico de infección producida por piv |
US20220273787A1 (en) | 2019-05-15 | 2022-09-01 | Janssen Vaccines & Prevention B.V. | Co-administration of seasonal influenza vaccine and an adenovirus based respiratory syncytial virus vaccine |
KR20220008816A (ko) | 2019-05-15 | 2022-01-21 | 얀센 백신스 앤드 프리벤션 비.브이. | 아데노바이러스 기반 백신을 사용한 호흡기 세포융합 바이러스 감염의 예방적 치료 |
US20220308055A1 (en) * | 2019-08-27 | 2022-09-29 | University Of Central Florida Research Foundation, Inc. | Method and device for pathogen or antibody detection using unmodified signaling substances with or without unlabeled detection reagents |
CN111166881B (zh) * | 2020-01-06 | 2023-03-24 | 国药中生生物技术研究院有限公司 | 一种重组呼吸道合胞病毒多表位嵌合疫苗及其制备方法和应用 |
BR112022019411A2 (pt) | 2020-04-02 | 2022-12-06 | Janssen Vaccines & Prevention Bv | Composições de vacina estabilizadas |
JP2023531554A (ja) | 2020-06-29 | 2023-07-24 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | 呼吸器合胞体ウイルス感染に対するワクチンの組み合わせ |
US20240059763A1 (en) * | 2020-12-18 | 2024-02-22 | Zhuhai Trinomab Pharmaceutical Co., Ltd. | Respiratory syncytial virus-specific binding molecule |
WO2022175479A1 (en) | 2021-02-19 | 2022-08-25 | Janssen Vaccines & Prevention B.V. | Vaccine combinations against respiratory syncytial virus strain a and b infections |
CN113249333B (zh) * | 2021-03-16 | 2023-06-02 | 贵州省人民医院 | 一种分泌抗呼吸道合胞病毒单克隆抗体的杂交瘤细胞株rsvn4c3 |
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Publication number | Publication date |
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EP2464664A1 (en) | 2012-06-20 |
CA2770737A1 (en) | 2011-02-17 |
JP2013501527A (ja) | 2013-01-17 |
NZ597996A (en) | 2014-02-28 |
IN2012DN01328A (pl) | 2015-06-05 |
IL217977A0 (en) | 2012-03-29 |
ZA201201007B (en) | 2019-08-28 |
KR101778317B1 (ko) | 2017-09-13 |
MX2012001882A (es) | 2012-04-11 |
CN102656189B (zh) | 2014-10-08 |
ES2553440T3 (es) | 2015-12-09 |
US20110076268A1 (en) | 2011-03-31 |
EA201200277A1 (ru) | 2012-09-28 |
US20140044719A1 (en) | 2014-02-13 |
BR112012003064B1 (pt) | 2021-03-16 |
BR112012003064B8 (pt) | 2021-05-25 |
JP5762408B2 (ja) | 2015-08-12 |
DK2464664T3 (da) | 2016-01-18 |
KR20120050480A (ko) | 2012-05-18 |
CA2770737C (en) | 2020-05-12 |
EA023179B1 (ru) | 2016-05-31 |
AU2010282312A1 (en) | 2012-02-23 |
EP2464664B1 (en) | 2015-09-23 |
BR112012003064A2 (pt) | 2017-11-14 |
WO2011020079A1 (en) | 2011-02-17 |
US8568719B2 (en) | 2013-10-29 |
HK1172350A1 (zh) | 2013-04-19 |
US9365638B2 (en) | 2016-06-14 |
SG178335A1 (en) | 2012-03-29 |
CN102656189A (zh) | 2012-09-05 |
IL217977A (en) | 2016-06-30 |
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