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PL2268267T3 - Kompozycja sucha transglutaminazy - Google Patents

Kompozycja sucha transglutaminazy

Info

Publication number
PL2268267T3
PL2268267T3 PL09735163T PL09735163T PL2268267T3 PL 2268267 T3 PL2268267 T3 PL 2268267T3 PL 09735163 T PL09735163 T PL 09735163T PL 09735163 T PL09735163 T PL 09735163T PL 2268267 T3 PL2268267 T3 PL 2268267T3
Authority
PL
Poland
Prior art keywords
transglutaminase composition
dry transglutaminase
dry
composition
transglutaminase
Prior art date
Application number
PL09735163T
Other languages
English (en)
Inventor
Mark Brader
Thomas Falck
Gunhild Klarskov Kristiansen
Original Assignee
Novo Nordisk Health Care Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Health Care Ag filed Critical Novo Nordisk Health Care Ag
Publication of PL2268267T3 publication Critical patent/PL2268267T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/104Aminoacyltransferases (2.3.2)
    • C12N9/1044Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/02Aminoacyltransferases (2.3.2)
    • C12Y203/02013Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
PL09735163T 2008-04-21 2009-04-20 Kompozycja sucha transglutaminazy PL2268267T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08103642 2008-04-21
EP09735163.9A EP2268267B1 (en) 2008-04-21 2009-04-20 Dry transglutaminase composition
PCT/EP2009/054657 WO2009130181A2 (en) 2008-04-21 2009-04-20 Dry transglutaminase composition

Publications (1)

Publication Number Publication Date
PL2268267T3 true PL2268267T3 (pl) 2017-12-29

Family

ID=40792660

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09735163T PL2268267T3 (pl) 2008-04-21 2009-04-20 Kompozycja sucha transglutaminazy

Country Status (12)

Country Link
US (1) US10391062B2 (pl)
EP (1) EP2268267B1 (pl)
JP (1) JP6244079B2 (pl)
KR (2) KR101897534B1 (pl)
CN (2) CN102065844A (pl)
AU (1) AU2009240026B2 (pl)
CA (1) CA2722230C (pl)
ES (1) ES2640343T3 (pl)
MX (1) MX349837B (pl)
PL (1) PL2268267T3 (pl)
RU (1) RU2616847C2 (pl)
WO (1) WO2009130181A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5929760B2 (ja) * 2010-12-07 2016-06-08 味の素株式会社 安定化酵素組成物及びその製造方法
US20180169117A1 (en) * 2014-03-20 2018-06-21 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical formulation comprising a substituted phenyl - (1,3-dihydro-isoindol-2-yl) - methanone
CN105462950B (zh) * 2016-02-16 2017-09-26 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
CN106337044B (zh) * 2016-09-30 2018-08-31 迈克生物股份有限公司 凝血酶溶液
SG11201908457WA (en) * 2017-03-15 2019-10-30 Cerecin Inc Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
JPS56135418A (en) 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
US4877608A (en) * 1987-11-09 1989-10-31 Rorer Pharmaceutical Corporation Pharmaceutical plasma protein formulations in low ionic strength media
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
JP2719166B2 (ja) * 1989-02-02 1998-02-25 鐘紡株式会社 毛髪化粧料組成物
DE3939346A1 (de) 1989-11-29 1991-06-06 Behringwerke Ag Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide
JPH03240738A (ja) 1990-02-20 1991-10-28 Hoechst Japan Ltd 糖尿病性壊疽治療剤
JP3281368B2 (ja) 1990-11-30 2002-05-13 味の素株式会社 安定化トランスグルタミナーゼ組成物及び保存法
JP3353383B2 (ja) * 1992-06-02 2002-12-03 味の素株式会社 酵素製剤及び結着成形食品の製造法
DE69326101T2 (de) 1992-06-02 2000-04-20 Ajinomoto Co., Inc. Verfahren zur Herstellung eines geformten gebundenen Nahrungsmittels
US5330974A (en) 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
EP0691850B1 (en) 1993-03-30 2002-09-25 Hoechst Japan Limited Factor xiii for treatment of skin wounds
AT402788B (de) 1993-08-03 1997-08-25 Immuno Ag Virussichere blutgerinnungsfaktor xiii-präparation
US5939385A (en) 1993-08-13 1999-08-17 Zymogenetics, Inc. Transglutaminase cross-linkable polypeptides and methods relating thereto
DE19508192A1 (de) 1995-03-09 1996-09-12 Behringwerke Ag Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung
JPH08333277A (ja) 1995-06-05 1996-12-17 Hoechst Japan Ltd ヒト血液凝固第xiii因子の安定化された水性液製剤
AUPN801296A0 (en) 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
EP1131110B1 (de) 1998-11-18 2006-03-29 ZLB Behring GmbH Stabilisierte proteinzubereitungen für einen gewebekleber
JP4200644B2 (ja) 1999-09-17 2008-12-24 味の素株式会社 食品加工用塩漬剤
ES2254414T3 (es) 2000-05-10 2006-06-16 Novo Nordisk Health Care Ag Composicion farmaceutica comprendiendo un factor vlla y un inhibidor tfpi.
KR20020092469A (ko) 2000-05-10 2002-12-11 노보 노르디스크 에이/에스 인자 VIIa 및 인자 XIII를 포함하는 제약학적조성물
JP2004512374A (ja) 2000-11-03 2004-04-22 ザイモジェネティクス,インコーポレイティド A型血友病の治療のための第xiii血液凝固因子の使用
JP2003055257A (ja) * 2001-08-10 2003-02-26 Nihon Pharmaceutical Co Ltd 安定な血液凝固第xiii因子製剤
GB0207092D0 (en) 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
GB0216001D0 (en) 2002-07-10 2002-08-21 Nat Blood Authority Process and composition
JP2004123566A (ja) 2002-09-30 2004-04-22 Nihon Pharmaceutical Co Ltd ヒト血漿由来血液凝固第xiii因子製剤およびその製造方法
CN101010333B (zh) * 2004-08-27 2013-08-14 诺和诺德医疗保健公司 从生物材料中纯化凝血因子xⅲ多肽
JP5074750B2 (ja) 2005-12-07 2012-11-14 一般財団法人化学及血清療法研究所 シクロデキストリン類を含有する液状フィブリノゲン製剤
JP2011520985A (ja) * 2008-05-22 2011-07-21 バクスター・インターナショナル・インコーポレイテッド 組織壊死を低下させるためのフィブリンシーラントにより送達されるvegf165

Also Published As

Publication number Publication date
CA2722230C (en) 2016-08-23
JP2011518206A (ja) 2011-06-23
CA2722230A1 (en) 2009-10-29
KR101897534B1 (ko) 2018-09-12
ES2640343T3 (es) 2017-11-02
RU2010145064A (ru) 2012-05-27
KR20110015552A (ko) 2011-02-16
RU2616847C2 (ru) 2017-04-18
WO2009130181A3 (en) 2010-07-15
AU2009240026A1 (en) 2009-10-29
MX2010011208A (es) 2010-11-12
EP2268267A2 (en) 2011-01-05
KR101710471B1 (ko) 2017-02-27
US20110165140A1 (en) 2011-07-07
JP6244079B2 (ja) 2017-12-06
US10391062B2 (en) 2019-08-27
KR20160124245A (ko) 2016-10-26
WO2009130181A2 (en) 2009-10-29
CN105925545A (zh) 2016-09-07
EP2268267B1 (en) 2017-06-14
AU2009240026B2 (en) 2014-05-29
MX349837B (es) 2017-08-16
CN102065844A (zh) 2011-05-18

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