[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

PL1656381T3 - Krystalizacja stałych postaci soli addycyjnych klopidogrelu - Google Patents

Krystalizacja stałych postaci soli addycyjnych klopidogrelu

Info

Publication number
PL1656381T3
PL1656381T3 PL04763994T PL04763994T PL1656381T3 PL 1656381 T3 PL1656381 T3 PL 1656381T3 PL 04763994 T PL04763994 T PL 04763994T PL 04763994 T PL04763994 T PL 04763994T PL 1656381 T3 PL1656381 T3 PL 1656381T3
Authority
PL
Poland
Prior art keywords
crystallisation
clopidogrel
addition salts
solid forms
clopidogrel addition
Prior art date
Application number
PL04763994T
Other languages
English (en)
Inventor
Berta Kotar-Jordan
Igor Simonic
Rok Zupet
Milos Ruzic
Marija Grcman
Anica Pecavar
Original Assignee
Krka Torvarna Zdravil D D Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Torvarna Zdravil D D Novo Mesto filed Critical Krka Torvarna Zdravil D D Novo Mesto
Publication of PL1656381T3 publication Critical patent/PL1656381T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
PL04763994T 2003-08-13 2004-08-11 Krystalizacja stałych postaci soli addycyjnych klopidogrelu PL1656381T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10337773A DE10337773A1 (de) 2003-08-13 2003-08-13 Kristallisation von festen Formen von Clopidogrel-Additionssalzen
EP04763994A EP1656381B1 (en) 2003-08-13 2004-08-11 Crystallisation of solid forms of clopidogrel addition salts
PCT/EP2004/008989 WO2005016931A2 (en) 2003-08-13 2004-08-11 Crystallisation of solid forms of clopidogrel addition salts

Publications (1)

Publication Number Publication Date
PL1656381T3 true PL1656381T3 (pl) 2011-08-31

Family

ID=34177655

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04763994T PL1656381T3 (pl) 2003-08-13 2004-08-11 Krystalizacja stałych postaci soli addycyjnych klopidogrelu

Country Status (9)

Country Link
EP (1) EP1656381B1 (pl)
AT (1) ATE501153T1 (pl)
DE (2) DE10337773A1 (pl)
ES (1) ES2362660T3 (pl)
HR (1) HRP20110418T1 (pl)
PL (1) PL1656381T3 (pl)
PT (1) PT1656381E (pl)
SI (1) SI1656381T1 (pl)
WO (1) WO2005016931A2 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7999106B2 (en) * 2004-04-19 2011-08-16 Krka, Tovarna Zdravil, D.D., Novo Mesto Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form I
EP1693375A1 (en) * 2005-02-21 2006-08-23 KRKA, tovarna zdravil, d.d., Novo mesto Process for preparing clopidrogel hydrogen sulfate of form I
EP1931682A2 (en) * 2006-08-03 2008-06-18 Teva Pharmaceutical Industries Ltd. Process for preparing clopidogrel bisulphate
SI22383A (sl) * 2006-09-22 2008-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze klopidogrela in nove oblike njegovih farmacevtsko sprejemljivih soli
KR101378596B1 (ko) 2006-12-27 2014-03-26 경동제약 주식회사 결정성 클로피도그렐 · 황산염 형태 ｉ의 제조방법
PL382055A1 (pl) * 2007-03-23 2008-09-29 Koźluk Tomasz Nobilus Ent Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu
EP2107061A1 (en) 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
CN102083837B (zh) * 2008-06-24 2013-09-18 Zach系统股份公司 硫酸氢氯吡格雷晶型i的制备方法
WO2011010318A1 (en) * 2009-07-23 2011-01-27 Praveen Laboratories Private Limited Process for the preparation of clopidogrel polymorphous form 1 using seed chrystals
WO2011042804A2 (en) 2009-10-08 2011-04-14 Jubliant Life Sciences Limited An improved process for the preparation of clopidogrel hydrogen sulfate form i
CN102432625A (zh) * 2011-11-05 2012-05-02 江南大学 一种制备高纯度i型氯吡格雷硫酸氢盐的结晶方法
CN102358743A (zh) * 2011-11-05 2012-02-22 江南大学 一种制备无定形氯吡格雷硫酸氢盐的简便方法
CN103044444B (zh) * 2013-01-21 2015-04-15 上海现代哈森（商丘）药业有限公司 一种高纯度ⅰ型(+)-(s)-硫酸氢氯吡格雷的合成方法
CN103923100B (zh) * 2014-04-03 2019-05-14 浙江华海药业股份有限公司 一种硫酸氢氯吡格雷的精制方法
CN104478895B (zh) * 2014-12-05 2017-04-12 广东东阳光药业有限公司 氯吡格雷硫酸盐的制备方法
CN107118221B (zh) * 2017-05-24 2021-09-07 常州制药厂有限公司 一种硫酸氢氯吡格雷晶型i制备方法
CN107163060B (zh) * 2017-05-24 2021-03-02 常州制药厂有限公司 一种硫酸氢氯吡格雷晶型ii制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2779726B1 (fr) * 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel
WO2003005162A2 (en) * 2001-07-02 2003-01-16 Wilson Thomas W Method and system for analyzing resource allocation
WO2003051362A2 (en) * 2001-12-18 2003-06-26 Teva Pharmaceutical Industries Ltd. Polymorphs of clopidogrel hydrogensulfate
CZ297472B6 (cs) * 2002-08-27 2006-12-13 Zentiva, A.S. Zpusob výroby clopidogrelu hydrogensulfátu krystalické formy I
WO2004048385A2 (en) * 2002-11-28 2004-06-10 Instytut Farmaceutyczny A process for the preparation of crystalline form 1 or clopidogrel hydrogen sulfate
EP1603920A1 (en) * 2003-03-12 2005-12-14 Cadila Healthcare Ltd. Polymorph and amorphous form of (s)-(+)-clopidogrel bisulfate

Also Published As

Publication number Publication date
DE10337773A1 (de) 2005-03-24
SI1656381T1 (sl) 2011-07-29
EP1656381A2 (en) 2006-05-17
PT1656381E (pt) 2011-06-16
ES2362660T3 (es) 2011-07-11
EP1656381B1 (en) 2011-03-09
WO2005016931A3 (en) 2005-04-28
DE602004031744D1 (de) 2011-04-21
ATE501153T1 (de) 2011-03-15
WO2005016931A2 (en) 2005-02-24
HRP20110418T1 (hr) 2011-06-30

Similar Documents

Publication Publication Date Title
PT1656381E (pt) Cristalização de formas sólidas de sais de adição de clopidogrel
UA93531C2 (en) Novel hydrogen sulfate salt
EP1672077A4 (en) PROCESS FOR PRODUCING SUCCINIC ACID
HK1112238A1 (en) Substituted benzo(d)isoxazol-3-yl amine compounds as analgesics
IS7319A (is) Fjölgervingar klópídógrelvetnissúlfats
BG111461A (en) TECHNICAL METHOD FOR OBTAINING TROPENOL
HK1104817A1 (en) Crystallisation and purification of glycopyrronium bromide
DE602004013405D1 (de) Polymorphe formen von valsartan
GB0308407D0 (en) Method of obtaining 68 GA
IL183700A0 (en) Process for production of (4,5-dihydroisoxazol-3-yl)thio-carboxamidine salts
MX2009005664A (es) D-isoglutamil-d-triptofano cristalino, y la sal monoamonica de d-isoglutamil-d-triptofano.
TW200420541A (en) Crystalline forms
RS20060297A (en) Rearranged pentanols, a method for the production thereof, and their use as antiphlogistics
TW200637832A (en) Process for preparing amorphous valsartan
AU2003285841A1 (en) A process for the preparation of crystalline form 1 or clopidogrel hydrogen sulfate
AU2003267565A8 (en) Process for the production of a fuel composition
MY147404A (en) Process for preparation of n-benzoyl-staurosporine
EP1535931A4 (en) PROCESS FOR THE PRODUCTION OF CRYSTALLINE 1,2-POLYBUTADIENE
ZA200800138B (en) Process for the preparation of crystalline perindopril
GB2422842B (en) Process for the production of multipurpose energy sources and multipurpose energy sources produced by said process
HRP20041017A2 (en) A process for the preparation of clopidogrel
AU2003241149A1 (en) Amorphous clopidogrel hydrogen sulfate composition
SG149005A1 (en) Process for the preparation of thiazolopyrimidines
EP1669458A4 (en) PROCESS FOR PRODUCING 1,4-DIHYDOXY-2-NAPHTHOTIC ACID
WO2007147480A3 (en) Polymorphic forms and process