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LV10268B - Therapeutically active substituted benzimidazole and process for its preparation - Google Patents

Therapeutically active substituted benzimidazole and process for its preparation Download PDF

Info

Publication number
LV10268B
LV10268B LVP-93-692A LV930692A LV10268B LV 10268 B LV10268 B LV 10268B LV 930692 A LV930692 A LV 930692A LV 10268 B LV10268 B LV 10268B
Authority
LV
Latvia
Prior art keywords
compound
benzimidazole
methyl
dimethoxy
pyridinyl
Prior art date
Application number
LVP-93-692A
Other languages
English (en)
Latvian (lv)
Other versions
LV10268A (lv
Inventor
Arne Elof Br Ndstrim
Per Lennart Lindberg
Carl Ingemar Starke
Gunnel Elisabeth Sunden
Original Assignee
H Ssle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Ssle Ab filed Critical H Ssle Ab
Publication of LV10268A publication Critical patent/LV10268A/xx
Publication of LV10268B publication Critical patent/LV10268B/lv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LVP-93-692A 1988-12-22 1993-06-28 Therapeutically active substituted benzimidazole and process for its preparation LV10268B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19888804628A SE8804628D0 (sv) 1988-12-22 1988-12-22 New compounds
PCT/SE1989/000741 WO1990006926A1 (en) 1988-12-22 1989-12-20 Therapeutically active substituted benzimidazole and process for its preparation

Publications (2)

Publication Number Publication Date
LV10268A LV10268A (lv) 1994-10-20
LV10268B true LV10268B (en) 1995-02-20

Family

ID=20374309

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-692A LV10268B (en) 1988-12-22 1993-06-28 Therapeutically active substituted benzimidazole and process for its preparation

Country Status (26)

Country Link
US (1) US5019584A (zh)
EP (1) EP0451188B1 (zh)
JP (1) JP2793907B2 (zh)
CN (1) CN1028232C (zh)
AT (1) ATE110379T1 (zh)
AU (1) AU636866B2 (zh)
CA (1) CA2005987C (zh)
DD (1) DD296077A5 (zh)
DE (1) DE68917738T2 (zh)
DK (1) DK170801B1 (zh)
FI (1) FI913036A0 (zh)
GR (1) GR1000318B (zh)
HU (1) HUT57203A (zh)
IE (1) IE64850B1 (zh)
IL (1) IL92797A (zh)
LT (1) LT3981B (zh)
LV (1) LV10268B (zh)
NO (1) NO178338C (zh)
PH (1) PH27257A (zh)
PT (1) PT92647B (zh)
RO (1) RO110496B1 (zh)
RU (1) RU2070199C1 (zh)
SE (1) SE8804628D0 (zh)
WO (1) WO1990006926A1 (zh)
YU (1) YU242589A (zh)
ZA (1) ZA899796B (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3049367B2 (ja) * 1990-06-20 2000-06-05 アストラゼネカ・アクチエボラーグ ジアルコキシ−ピリジニル−ベンズイミダゾール誘導体、その製造方法およびそれを含む医薬
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
US6016044A (en) * 1995-09-11 2000-01-18 Alaris Medical Systems, Inc. Open-loop step motor control system
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
MXPA04007169A (es) * 2002-01-25 2004-10-29 Santarus Inc Suministro transmucosal de inhibidores de bomba de protones.
AU2003224781A1 (en) * 2002-03-26 2003-10-13 Dr. Reddy's Laboratories Limited Crystalline forms of rabeprazole sodium
JP2006518751A (ja) * 2003-02-20 2006-08-17 サンタラス インコーポレイティッド 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AU2004257864A1 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US20050037070A1 (en) * 2003-07-18 2005-02-17 Santarus, Inc. Pharmaceutical formulatins useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (zh) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4331671A (en) * 1981-01-09 1982-05-25 Sterling Drug Inc. 5-(Pyridinyl)-1H-benzimidazoles and 1-hydroxy-6-(pyridinyl)-1H-benzimidazoles and their cardiotonic use
HU195220B (en) 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
GB8610607D0 (en) * 1986-04-30 1986-06-04 Smith Kline French Lab Chemical compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
HU886738D0 (en) * 1987-10-30 1990-02-28 Haessle Ab Process for the preparation of pharmaceutical compositions against osteoporosis containing 2-pyridinyl-methyl-(sulfinyl or thio)-benzimidazoles

Also Published As

Publication number Publication date
DE68917738T2 (de) 1994-12-22
CA2005987A1 (en) 1990-06-22
FI913036A0 (fi) 1991-06-20
RO110496B1 (ro) 1996-01-30
DE68917738D1 (de) 1994-09-29
DK122391A (da) 1991-06-24
IE64850B1 (en) 1995-09-06
PT92647A (pt) 1990-06-29
NO178338B (no) 1995-11-27
HUT57203A (en) 1991-11-28
HU901085D0 (en) 1991-09-30
LT3981B (en) 1996-06-25
NO912416D0 (no) 1991-06-20
CN1043714A (zh) 1990-07-11
DD296077A5 (de) 1991-11-21
JP2793907B2 (ja) 1998-09-03
IL92797A (en) 1994-12-29
NO178338C (no) 1996-03-06
IL92797A0 (en) 1990-09-17
IE894049L (en) 1990-06-22
EP0451188A1 (en) 1991-10-16
PH27257A (en) 1993-05-04
AU636866B2 (en) 1993-05-13
RU2070199C1 (ru) 1996-12-10
JPH04502462A (ja) 1992-05-07
NO912416L (no) 1991-07-31
DK170801B1 (da) 1996-01-22
GR890100834A (en) 1991-03-15
EP0451188B1 (en) 1994-08-24
SE8804628D0 (sv) 1988-12-22
LTIP1722A (en) 1995-07-25
PT92647B (pt) 1995-09-12
GR1000318B (el) 1992-06-25
CN1028232C (zh) 1995-04-19
YU242589A (en) 1991-04-30
DK122391D0 (da) 1991-06-21
US5019584A (en) 1991-05-28
CA2005987C (en) 1999-04-13
WO1990006926A1 (en) 1990-06-28
ATE110379T1 (de) 1994-09-15
ZA899796B (en) 1990-08-29
AU4817690A (en) 1990-07-10
LV10268A (lv) 1994-10-20

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