LU79087A1 - Procede de preparation de quinazolines - Google Patents

Procede de preparation de quinazolines

Info

Publication number: LU79087A1
Authority: LU; Luxembourg
Prior art keywords: quinazolines; preparing; preparing quinazolines
Prior art date: 1977-02-22

Application number

LU79087A

Other languages

English (en)

Inventor

R Partyka

R Crenshaw

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-22

Filing date

1978-02-20

Publication date

1978-09-28

1978-02-20 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1978-09-28 Publication of LU79087A1 publication Critical patent/LU79087A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

LU79087A 1977-02-22 1978-02-20 Procede de preparation de quinazolines LU79087A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/770,966 US4101548A (en)	1977-02-22	1977-02-22	1,2,3-Thiadiazole amides

Publications (1)

Publication Number	Publication Date
LU79087A1 true LU79087A1 (fr)	1978-09-28

Family

ID=25090261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU79087A LU79087A1 (fr)	1977-02-22	1978-02-20	Procede de preparation de quinazolines

Country Status (19)

Country	Link
US (1)	US4101548A (fr)
JP (1)	JPS53103485A (fr)
AU (1)	AU518108B2 (fr)
BE (1)	BE864095A (fr)
CA (1)	CA1121820A (fr)
CH (1)	CH634318A5 (fr)
DE (1)	DE2807392A1 (fr)
DK (1)	DK75178A (fr)
FI (1)	FI780566A (fr)
FR (1)	FR2381046A1 (fr)
GB (1)	GB1586556A (fr)
GR (1)	GR67024B (fr)
IE (1)	IE46652B1 (fr)
IT (1)	IT1105287B (fr)
LU (1)	LU79087A1 (fr)
NL (1)	NL7801996A (fr)
SE (1)	SE7802022L (fr)
YU (4)	YU32178A (fr)
ZA (1)	ZA78992B (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2728523C2 (de) *	1977-06-23	1986-02-27	Schering AG, 1000 Berlin und 4709 Bergkamen	4-Methyl-1,2,3-thiadiazol-5-carbonsäure-(cyclohexylmethyl)-amid, Mittel mit herbizider und wachstumsregulatorischer Wirkung enthaltend diese Verbindung sowie Verfahren zu seiner Herstellung
US4309541A (en) *	1978-09-20	1982-01-05	Ciba-Geigy Corporation	Piperidinyl-lactams
US4287341A (en) *	1979-11-01	1981-09-01	Pfizer Inc.	Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US4351940A (en) *	1980-03-03	1982-09-28	Pfizer Inc.	Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines
US4377581A (en) *	1980-03-03	1983-03-22	Pfizer Inc.	Chloro- and alkoxy-substituted-2,4-diaminoquinazolines
JPS5791987A (en) *	1980-11-26	1982-06-08	Sankyo Co Ltd	Aminoquinazoline derivative and its preparation
FI70411C (fi) *	1980-12-29	1986-09-19	Pfizer	Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4367335A (en) *	1981-08-03	1983-01-04	Mead Johnson & Company	Thiazolidinylalkylene piperazine derivatives
GB8320958D0 (en) *	1983-08-03	1983-09-07	Pfizer Ltd	Quinazoline cardiac stimulants
US5776962A (en) *	1994-08-03	1998-07-07	Cell Pathways, Inc.	Lactone compounds for treating patient with precancerous lesions
US5696159A (en) *	1994-08-03	1997-12-09	Cell Pathways, Inc.	Lactone compounds for treating patients with precancerous lesions
US6200980B1 (en)	1995-06-07	2001-03-13	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl purinone derivatives
US6262059B1 (en)	1995-06-07	2001-07-17	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with quinazoline derivatives
US6060477A (en) *	1995-06-07	2000-05-09	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives
US6046216A (en) *	1995-06-07	2000-04-04	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl pyridinone derivatives
US6232312B1 (en)	1995-06-07	2001-05-15	Cell Pathways, Inc.	Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides
US5874440A (en) *	1995-06-07	1999-02-23	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl pyrimidinone derivatives
US6046206A (en) *	1995-06-07	2000-04-04	Cell Pathways, Inc.	Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
CA2232138A1 (fr) *	1995-09-29	1997-04-03	William C. Lumma	Antagonistes du recepteur adrenergique alpha 1b
US5858694A (en) *	1997-05-30	1999-01-12	Cell Pathways, Inc.	Method for identifying compounds for inhibition of cancerous lesions
CA2238283C (fr)	1997-05-30	2002-08-20	Cell Pathways, Inc.	Methode d'identification de composes visant a inhiber les lesions neoplasiques, compositions pharmaceutiques a prtir de ces composes et compositions pour traiter les lesions neoplasiques
US5852035A (en) *	1997-12-12	1998-12-22	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to substituted N- arylmethyl and heterocyclmethyl-1H-pyrazolo (3,4-B) quinolin-4-amines
US6046199A (en) *	1998-01-14	2000-04-04	Cell Pathways, Inc.	Method of inhibiting neoplastic cells with tetracyclic pyrido[3,4-B]indole derivatives
US6410584B1 (en) *	1998-01-14	2002-06-25	Cell Pathways, Inc.	Method for inhibiting neoplastic cells with indole derivatives
US5942520A (en) *	1998-01-27	1999-08-24	Cell Pathways, Inc.	Method for inhibiting neoplastic cells by exposure to substituted N-cycloalkylmethyl-1-H-pyrazolo (3,4-B) quinolone-4 amines
US5990117A (en) *	1998-04-15	1999-11-23	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives
US6180629B1 (en)	1998-08-14	2001-01-30	Cell Pathways, Inc.	[4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia
US6124303A (en) *	1998-09-11	2000-09-26	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 9-substituted 2-(2-N-aloxyphenyl) purin-6-ones
US6268372B1 (en)	1998-09-11	2001-07-31	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 2,9-disubstituted purin-6-ones
US6130053A (en) *	1999-08-03	2000-10-10	Cell Pathways, Inc.	Method for selecting compounds for inhibition of neoplastic lesions
US6200771B1 (en)	1998-10-15	2001-03-13	Cell Pathways, Inc.	Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia
US6133271A (en) *	1998-11-19	2000-10-17	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
US6187779B1 (en)	1998-11-20	2001-02-13	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives
US6369092B1 (en)	1998-11-23	2002-04-09	Cell Pathways, Inc.	Method for treating neoplasia by exposure to substituted benzimidazole derivatives
US6077842A (en) *	1998-11-24	2000-06-20	Cell Pathways, Inc.	Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives
US6034099A (en) *	1998-11-24	2000-03-07	Cell Pathways, Inc.	Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones
US6486155B1 (en)	1998-11-24	2002-11-26	Cell Pathways Inc	Method of inhibiting neoplastic cells with isoquinoline derivatives
US6025394A (en)	1999-01-29	2000-02-15	Cell Pathways, Inc.	Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols
US6020379A (en) *	1999-02-19	2000-02-01	Cell Pathways, Inc.	Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia
US6555547B1 (en)	2000-02-28	2003-04-29	Cell Pathways, Inc.	Method for treating a patient with neoplasia by treatment with a vinca alkaloid derivative
US6569638B1 (en)	2000-03-03	2003-05-27	Cell Pathways, Inc	Method for screening compounds for the treatment of neoplasia
US6420400B1 (en)	2000-04-07	2002-07-16	Kinetek Pharmaceuticals, Inc.	Antiproliferative 1,2,3-thiadiazole compounds
US7022702B2 (en)	2000-04-07	2006-04-04	Qlt Inc.	Antiproliferative 1,2,3-thiadiazole compounds
US6962940B2 (en)	2002-03-20	2005-11-08	Celgene Corporation	(+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7893101B2 (en) *	2002-03-20	2011-02-22	Celgene Corporation	Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7276529B2 (en) *	2002-03-20	2007-10-02	Celgene Corporation	Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7208516B2 (en) *	2002-03-20	2007-04-24	Celgene Corporation	Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
ZA200408369B (en) *	2002-04-12	2006-11-29	Celgene Corp	Methods for identification of modulators of angiogenesis, compounds discovered thereby, and methods of treatment using the compounds
KR20050000400A (ko) *	2002-04-12	2005-01-03	셀진 코포레이션	줄기 및 전구 세포 분화의 조절, 측정 및 이들의 용도
US20070155791A1 (en) *	2005-12-29	2007-07-05	Zeldis Jerome B	Methods for treating cutaneous lupus using aminoisoindoline compounds
JP2011515469A (ja) *	2008-03-24	2011-05-19	セルジーンコーポレイション	シクロプロピル−ｎ−｛２−［（１ｓ）−１−（３−エトキシ−４−メトキシフェニル）−２−（メチルスルホニル）エチル］−３−オキソイソインドリン−４−イル｝カルボキサミドを使用した乾癬又は乾癬性関節炎の治療
WO2015200177A1 (fr)	2014-06-23	2015-12-30	Celgene Corporation	Utilisation d'aprémilast pour le traitement d'une maladie hépatique ou d'une anomalie de la fonction hépatique

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE942029C (de) *	1951-06-22	1956-04-26	American Cyanamid Co	Verfahren zur Herstellung von neuen, in 1-Stellung substituierten 4-Aminopiperazinderivaten
US3812127A (en) *	1966-10-31	1974-05-21	Pfizer	4-(quinolin-4-yl)piperazine-1-carboxylic acid esters
US3517005A (en) *	1967-10-26	1970-06-23	Pfizer & Co C	Certain 2- and 4-substituted quinazolines
US3511836A (en) *	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3663706A (en) *	1969-09-29	1972-05-16	Pfizer	Use of 2,4-diaminoquinazolines as hypotensive agents
US3594980A (en) *	1969-10-03	1971-07-27	Charles C Diehl	Treating polluted gases in baffle chamber
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines
US3780040A (en) *	1972-06-02	1973-12-18	R Schnettler	2-substituted-3,4-dihydroquinazolines
JPS4966691A (fr) *	1972-10-30	1974-06-27
US4001237A (en) *	1976-02-18	1977-01-04	Bristol-Myers Company	Oxazole, isoxazole, thiazole and isothiazole amides
US4001238A (en) *	1976-02-18	1977-01-04	Bristol-Myers Company	1,3,4-oxadiazole amides
US4138561A (en) *	1977-09-30	1979-02-06	Bristol-Myers Company	Cyanocarboxamidines and quinazoline process

1977
- 1977-02-22 US US05/770,966 patent/US4101548A/en not_active Expired - Lifetime
1978
- 1978-02-06 CA CA000296307A patent/CA1121820A/fr not_active Expired
- 1978-02-08 GR GR55385A patent/GR67024B/el unknown
- 1978-02-13 AU AU33224/78A patent/AU518108B2/en not_active Expired
- 1978-02-13 YU YU00321/78A patent/YU32178A/xx unknown
- 1978-02-17 JP JP1669078A patent/JPS53103485A/ja active Pending
- 1978-02-17 BE BE185288A patent/BE864095A/fr not_active IP Right Cessation
- 1978-02-20 DK DK75178A patent/DK75178A/da not_active Application Discontinuation
- 1978-02-20 LU LU79087A patent/LU79087A1/fr unknown
- 1978-02-20 ZA ZA00780992A patent/ZA78992B/xx unknown
- 1978-02-21 GB GB6846/78A patent/GB1586556A/en not_active Expired
- 1978-02-21 DE DE19782807392 patent/DE2807392A1/de not_active Withdrawn
- 1978-02-21 FR FR7804955A patent/FR2381046A1/fr active Granted
- 1978-02-21 IT IT48131/78A patent/IT1105287B/it active
- 1978-02-21 IE IE369/78A patent/IE46652B1/en unknown
- 1978-02-21 SE SE7802022A patent/SE7802022L/xx unknown
- 1978-02-21 FI FI780566A patent/FI780566A/fi not_active Application Discontinuation
- 1978-02-22 NL NL7801996A patent/NL7801996A/xx not_active Application Discontinuation
- 1978-02-22 CH CH193778A patent/CH634318A5/fr not_active IP Right Cessation
1982
- 1982-09-02 YU YU01982/82A patent/YU198282A/xx unknown
- 1982-09-02 YU YU01984/82A patent/YU198482A/xx unknown
- 1982-09-02 YU YU01983/82A patent/YU198382A/xx unknown

Also Published As

Publication number	Publication date
YU198282A (en)	1983-01-21
IT7848131A0 (it)	1978-02-21
BE864095A (fr)	1978-08-17
CA1121820A (fr)	1982-04-13
SE7802022L (sv)	1978-08-23
GR67024B (fr)	1981-05-20
IE780369L (en)	1978-08-22
IE46652B1 (en)	1983-08-10
YU198382A (en)	1983-01-21
JPS53103485A (en)	1978-09-08
CH634318A5 (fr)	1983-01-31
DE2807392A1 (de)	1978-08-24
DK75178A (da)	1978-08-23
FI780566A (fi)	1978-08-23
AU518108B2 (en)	1981-09-17
YU198482A (en)	1983-01-21
IT1105287B (it)	1985-10-28
US4101548A (en)	1978-07-18
ZA78992B (en)	1979-09-26
GB1586556A (en)	1981-03-18
NL7801996A (nl)	1978-08-24
FR2381046B1 (fr)	1982-11-12
YU32178A (en)	1983-01-21
AU3322478A (en)	1979-08-23
FR2381046A1 (fr)	1978-09-15

Publication	Publication Date	Title
LU79087A1 (fr)	1978-09-28	Procede de preparation de quinazolines
LU80084A1 (fr)	1979-09-07	Procede de preparation d'oligoimides
BE858771A (fr)	1978-01-16	Procede de preparation de bitumes-polymeres
BE873136A (fr)	1979-06-28	Procede de preparation de la vincadifformine
LU79968A1 (fr)	1979-04-09	Procede de preparation de la meta-trifluoromethylphenyl-piperazine
BE865808A (fr)	1978-10-09	Procede de preparation de l'ethylene-glycol
BE865661A (fr)	1978-10-04	Procede de preparation de 3-alkyl-butene-1-als
BE865201A (fr)	1978-09-22	Procede de preparation de 1-amino-3-aryloxy-2-propanols
BE870162A (fr)	1979-03-01	Procede de preparation de p-benzoquinonediacetals
BE864280A (fr)	1978-08-24	Procede de preparation de m-bromo-alpha,alpha, alpha,-trifluorotoluenes
BE852850A (fr)	1977-09-26	Procede de preparation de la 5-acetoacetyl-amino-benzimidazolone
BE861064A (fr)	1978-03-16	Procede de preparation de siph2nylamine styrenee
BE865532A (fr)	1978-10-02	Procede de preparation de 2,2-dimethylolalcanals
BE862992A (fr)	1978-05-16	Procede de preparation de composes azotes
PT68138A (fr)	1978-07-01	Procede de preparation de methoxy-2 benzamides
BE870104A (fr)	1979-02-28	Procede de preparation de 2-chlorosulfinyl-azetidin-4-ones
BE872842A (fr)	1979-04-17	Procede de preparation de derives de 1-hydroxyaporphine
BE865667A (fr)	1978-07-31	Procede de preparation de trihalogenures de monohydrocarbyletain
BE866904A (fr)	1978-09-01	Procede de preparation de 3-bromophtalide
BE872383A (fr)	1979-05-29	Procede de preparation de phenylbutenones
BE856410A (fr)	1978-01-04	Procede de preparation de cis-hexahydrodibenzopyranones
BE867406A (fr)	1978-11-24	Procede de preparation de revetements
BE861501A (fr)	1978-06-05	Procede de preparation de la 17alpha-hydroxy-21-acetoxy-progesterone
BE871929A (fr)	1979-03-01	Procede de preparation de cyclopentene
BE870978A (fr)	1979-04-03	Procede de preparation de la (-)-vincamine