LT3044211T - Antibakteriniai 2h-indazolo dariniai - Google Patents
Antibakteriniai 2h-indazolo dariniaiInfo
- Publication number
- LT3044211T LT3044211T LTEP14781948.6T LT14781948T LT3044211T LT 3044211 T LT3044211 T LT 3044211T LT 14781948 T LT14781948 T LT 14781948T LT 3044211 T LT3044211 T LT 3044211T
- Authority
- LT
- Lithuania
- Prior art keywords
- antibacterial
- indazole derivatives
- indazole
- derivatives
- Prior art date
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/65031—Five-membered rings having the nitrogen atoms in the positions 1 and 2
- C07F9/65038—Five-membered rings having the nitrogen atoms in the positions 1 and 2 condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2013058537 | 2013-09-13 | ||
| PCT/IB2014/064458 WO2015036964A1 (en) | 2013-09-13 | 2014-09-12 | Antibacterial 2h-indazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3044211T true LT3044211T (lt) | 2018-04-10 |
Family
ID=51688371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP14781948.6T LT3044211T (lt) | 2013-09-13 | 2014-09-12 | Antibakteriniai 2h-indazolo dariniai |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9802901B2 (lt) |
| EP (1) | EP3044211B1 (lt) |
| JP (1) | JP6353909B2 (lt) |
| KR (1) | KR20160055889A (lt) |
| CN (1) | CN105531264B (lt) |
| AR (1) | AR097617A1 (lt) |
| AU (1) | AU2014319966B2 (lt) |
| BR (1) | BR112016007757A8 (lt) |
| CA (1) | CA2923146A1 (lt) |
| CL (1) | CL2016000568A1 (lt) |
| CY (1) | CY1120111T1 (lt) |
| DK (1) | DK3044211T3 (lt) |
| EA (1) | EA031562B1 (lt) |
| ES (1) | ES2662894T3 (lt) |
| HR (1) | HRP20180484T1 (lt) |
| HU (1) | HUE038519T2 (lt) |
| IL (1) | IL244500B (lt) |
| LT (1) | LT3044211T (lt) |
| MA (1) | MA38948B1 (lt) |
| MX (1) | MX361733B (lt) |
| MY (1) | MY179283A (lt) |
| PH (1) | PH12016500480A1 (lt) |
| PL (1) | PL3044211T3 (lt) |
| PT (1) | PT3044211T (lt) |
| SG (1) | SG11201601889YA (lt) |
| SI (1) | SI3044211T1 (lt) |
| TW (1) | TWI646084B (lt) |
| UA (1) | UA116484C2 (lt) |
| WO (1) | WO2015036964A1 (lt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3083567T3 (pl) | 2013-12-19 | 2018-08-31 | Idorsia Pharmaceuticals Ltd | Przeciwbakteryjne pochodne 1h-indazolu i 1h-indolu |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| AU2015261540A1 (en) | 2014-05-16 | 2017-01-12 | Idorsia Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
| EP3221300B1 (en) | 2014-11-19 | 2019-03-20 | Idorsia Pharmaceuticals Ltd | Antibacterial benzothiazole derivatives |
| AR105646A1 (es) * | 2015-08-11 | 2017-10-25 | Actelion Pharmaceuticals Ltd | Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida |
| TW201718484A (zh) * | 2015-08-28 | 2017-06-01 | 艾克泰聯製藥有限公司 | 抗菌環化吡咯啶-2-酮衍生物 |
| AR105848A1 (es) * | 2015-08-31 | 2017-11-15 | Actelion Pharmaceuticals Ltd | Derivados heterocíclicos antibacterianos |
| AR105889A1 (es) | 2015-09-03 | 2017-11-22 | Actelion Pharmaceuticals Ltd | Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos |
| CN109153673A (zh) * | 2016-05-17 | 2019-01-04 | 爱杜西亚药品有限公司 | 6-(丁-1,3-二炔-1-基)苯并[d]噻唑衍生物 |
| WO2019038362A1 (en) | 2017-08-24 | 2019-02-28 | Idorsia Pharmaceuticals Ltd | ANTIBACTERIAL PYRROLOIMIDAZOLONES |
| CN113372276B (zh) * | 2021-05-25 | 2022-04-22 | 三峡大学 | 吲唑类衍生物及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2469304A1 (en) | 2001-12-05 | 2003-06-19 | Ortho-Mcneil Pharmaceutical, Inc. | 6-o acyl ketolide antibacterials |
| US6806279B2 (en) | 2001-12-17 | 2004-10-19 | Sunesis Pharmaceuticals, Inc. | Small-molecule inhibitors of interleukin-2 |
| HUE025767T2 (en) | 2002-03-13 | 2016-05-30 | Array Biopharma Inc | N3-alkylated benzimidazole derivatives as MEK inhibitors |
| DE102004017930A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| AU2005313912A1 (en) | 2004-12-10 | 2006-06-15 | Emory University | 2' and 3' - substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation |
| PL1863818T3 (pl) | 2005-03-23 | 2010-08-31 | Hoffmann La Roche | Pochodne acetylenylo-pirazolo-pirymidyny jako antagoniści MGLUR2 |
| WO2008154642A2 (en) | 2007-06-12 | 2008-12-18 | Achaogen, Inc. | Antibacterial agents |
| DE102008044132A1 (de) | 2008-11-27 | 2010-06-02 | BSH Bosch und Siemens Hausgeräte GmbH | Kältegerät mit zweiseitig anschlagbarer Tür |
| WO2010100475A1 (en) | 2009-03-02 | 2010-09-10 | Astrazeneca Ab | Hydroxamic acid derivatives as gram-negative antibacterial agents |
| US8372807B2 (en) | 2009-05-20 | 2013-02-12 | Ardea Biosciences, Inc. | Methods of modulating uric acid levels |
| EP2451790A4 (en) | 2009-07-07 | 2012-12-26 | Anthem Biosciences Private Ltd | INHIBITORS OF HISTONE DEACETYLASE |
| US8853258B2 (en) * | 2009-10-13 | 2014-10-07 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| DK2512474T3 (en) | 2009-12-16 | 2014-12-01 | Pfizer | N-linked hydroxamic acid derivatives which can be used as antibacterial agents |
| GB2483736B (en) | 2010-09-16 | 2012-08-29 | Aragon Pharmaceuticals Inc | Estrogen receptor modulators and uses thereof |
| AU2011367819A1 (en) | 2010-11-10 | 2013-05-02 | Achaogen, Inc. | Hydroxamic acid derivatives and their use in the treatment of bacterial infections |
| KR20120079015A (ko) | 2011-01-03 | 2012-07-11 | 한미약품 주식회사 | Ｇ 단백질-커플링된 수용체의 조절을 위한 신규한 비사이클릭 화합물 |
| AP3336A (en) * | 2011-03-07 | 2015-07-31 | Pfizer | Fluoro-pyridinone derivatives useful as antibacterial agents |
| JP2014514299A (ja) * | 2011-04-08 | 2014-06-19 | ファイザー・インク | 抗菌剤として有用なイミダゾール、ピラゾールおよびトリアゾール誘導体 |
| AU2012238374B2 (en) | 2011-04-08 | 2015-04-02 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| WO2013170030A1 (en) | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| PL3083567T3 (pl) | 2013-12-19 | 2018-08-31 | Idorsia Pharmaceuticals Ltd | Przeciwbakteryjne pochodne 1h-indazolu i 1h-indolu |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| AU2015261540A1 (en) | 2014-05-16 | 2017-01-12 | Idorsia Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
-
2014
- 2014-09-10 AR ARP140103376A patent/AR097617A1/es unknown
- 2014-09-12 BR BR112016007757A patent/BR112016007757A8/pt not_active Application Discontinuation
- 2014-09-12 KR KR1020167009718A patent/KR20160055889A/ko not_active Application Discontinuation
- 2014-09-12 CA CA2923146A patent/CA2923146A1/en not_active Abandoned
- 2014-09-12 PT PT147819486T patent/PT3044211T/pt unknown
- 2014-09-12 EP EP14781948.6A patent/EP3044211B1/en not_active Not-in-force
- 2014-09-12 HU HUE14781948A patent/HUE038519T2/hu unknown
- 2014-09-12 LT LTEP14781948.6T patent/LT3044211T/lt unknown
- 2014-09-12 CN CN201480049877.8A patent/CN105531264B/zh not_active Expired - Fee Related
- 2014-09-12 MY MYPI2016700850A patent/MY179283A/en unknown
- 2014-09-12 DK DK14781948.6T patent/DK3044211T3/en active
- 2014-09-12 MX MX2016003196A patent/MX361733B/es active IP Right Grant
- 2014-09-12 WO PCT/IB2014/064458 patent/WO2015036964A1/en active Application Filing
- 2014-09-12 SI SI201430662T patent/SI3044211T1/en unknown
- 2014-09-12 MA MA38948A patent/MA38948B1/fr unknown
- 2014-09-12 EA EA201600248A patent/EA031562B1/ru not_active IP Right Cessation
- 2014-09-12 JP JP2016542426A patent/JP6353909B2/ja not_active Expired - Fee Related
- 2014-09-12 US US15/021,649 patent/US9802901B2/en not_active Expired - Fee Related
- 2014-09-12 TW TW103131666A patent/TWI646084B/zh not_active IP Right Cessation
- 2014-09-12 SG SG11201601889YA patent/SG11201601889YA/en unknown
- 2014-09-12 AU AU2014319966A patent/AU2014319966B2/en not_active Ceased
- 2014-09-12 PL PL14781948T patent/PL3044211T3/pl unknown
- 2014-09-12 ES ES14781948.6T patent/ES2662894T3/es active Active
- 2014-12-09 UA UAA201603879A patent/UA116484C2/uk unknown
-
2016
- 2016-03-08 IL IL244500A patent/IL244500B/en not_active IP Right Cessation
- 2016-03-10 CL CL2016000568A patent/CL2016000568A1/es unknown
- 2016-03-11 PH PH12016500480A patent/PH12016500480A1/en unknown
-
2018
- 2018-03-23 HR HRP20180484TT patent/HRP20180484T1/hr unknown
- 2018-03-30 CY CY20181100362T patent/CY1120111T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1215795A1 (zh) | 鵝膏毒素衍生物 | |
| SG11201506100XA (en) | Pyridazinone-amides derivatives | |
| IL244500B (en) | History of h2–indazole antibacterials | |
| HK1221459A1 (zh) | 抗菌雙芳香族衍生物 | |
| ZA201601333B (en) | Oxoquinazolinyl-butanamide derivatives | |
| SG11201605189YA (en) | Imidazopyrazinone derivatives | |
| HK1213566A1 (zh) | 新的四唑酮衍生物 | |
| SG11201604752SA (en) | Antibacterial peptide-inducing agent | |
| HK1221468A1 (zh) | 酞嗪衍生物 | |
| HK1219903A1 (zh) | 抗菌化合物 | |
| EP3009444A4 (en) | ALPHA-oxoacyl-Amino-caprolactam derivative | |
| GB201306609D0 (en) | Antibacterial drug derivatives | |
| GB201306608D0 (en) | Antibacterial drug derivatives | |
| GB201301396D0 (en) | Ar |